Conserved subnet 1:
115 conserved interactions between 83 ortholog groups.
This subnet exists in 3 organisms (p<5e-206).

Ortholog Groups
KOG1036	Mitotic spindle checkpoint protein BUB3, WD repeat superfamily
KOG1166	Mitotic checkpoint serine/threonine protein kinase
KOG0668	Casein kinase II, alpha subunit
KOG3092	Casein kinase II, beta subunit
KOG0746	60S ribosomal protein L3 and related proteins
KOG1628	40S ribosomal protein S3A
KOG4212	RNA-binding protein hnRNP-M
KOG0901	60S ribosomal protein L14/L17/L23
KOG0653	Cyclin B and related kinase-activating proteins
KOG3484	Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins
KOG1588	RNA-binding protein Sam68 and related KH domain proteins
KOG0830	40S ribosomal protein SA (P40)/Laminin receptor 1
KOG1350	F0F1-type ATP synthase, beta subunit
KOG0676	Actin and related proteins
KOG0819	Annexin
KOG2309	60s ribosomal protein L2/L8
KOG1475	Ribosomal protein RPL1/RPL2/RL4L4
KOG3544	Collagens (type IV and type XIII), and related proteins
KOG2169	Zn-finger transcription factor
KOG2294	Transcription factor of the Forkhead/HNF3 family
KOG0864	Ran-binding protein RANBP1 and related RanBD domain proteins
KOG1074	Transcriptional repressor SALM
KOG3528	FOG: PDZ domain
KOG3550	Receptor targeting protein Lin-7
KOG0603	Ribosomal protein S6 kinase
KOG3529	Radixin, moesin and related proteins of the ERM family
KOG0580	Serine/threonine protein kinase
KOG4441	Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
KOG4582	Uncharacterized conserved protein, contains ZZ-type Zn-finger
KOG1704	FOG: LIM domain
KOG3002	Zn finger protein
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG3681	Alpha-catenin
HG32204	Homologene family 32204
KOG1218	Proteins containing Ca2+-binding EGF-like domains
KOG4211	Splicing factor hnRNP-F and related RNA-binding proteins
KOG2272	Focal adhesion protein PINCH-1, contains LIM domains
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG1217	Fibrillins and related proteins containing Ca2+-binding EGF-like domains
KOG0815	60S acidic ribosomal protein P0
KOG2165	Anaphase-promoting complex (APC), subunit 2
KOG2332	Ferritin
KOG1215	Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains
KOG0594	Protein kinase PCTAIRE and related kinases
KOG3575	FOG: Hormone receptors
KOG0665	Jun-N-terminal kinase (JNK)
KOG2012	Ubiquitin activating enzyme UBA1
KOG1450	Predicted Rho GTPase-activating protein
KOG1219	Uncharacterized conserved protein, contains laminin, cadherin and EGF domains
KOG2441	mRNA splicing factor/probable chromatin binding snw family nuclear protein
KOG2462	C2H2-type Zn-finger protein
KOG3834	Golgi reassembly stacking protein GRASP65, contains PDZ domain
KOG3667	STAT protein
KOG3119	Basic region leucine zipper transcription factor
KOG2330	Splicing factor 3b, subunit 2
KOG1892	Actin filament-binding protein Afadin
KOG0586	Serine/threonine protein kinase
KOG0841	Multifunctional chaperone (14-3-3 family)
KOG0657	Glyceraldehyde 3-phosphate dehydrogenase
KOG0660	Mitogen-activated protein kinase
KOG3701	TGFbeta receptor signaling protein SMAD and related proteins
KOG4297	C-type lectin
KOG3991	Uncharacterized conserved protein
KOG3780	Thioredoxin binding protein TBP-2/VDUP1
KOG2260	Cell division cycle 37 protein, CDC37
KOG1700	Regulatory protein MLP and related LIM proteins
KOG1721	FOG: Zn-finger
KOG1973	Chromatin remodeling protein, contains PHD Zn-finger
KOG1342	Histone deacetylase complex, catalytic component RPD3
KOG0749	Mitochondrial ADP/ATP carrier proteins
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG1911	Heterochromatin-associated protein HP1 and related CHROMO domain proteins
KOG1923	Rac1 GTPase effector FRL
KOG4228	Protein tyrosine phosphatase
KOG3606	Cell polarity protein PAR6
KOG3070	Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing
KOG2373	Predicted mitochondrial DNA helicase twinkle
KOG1878	Nuclear receptor coregulator SMRT/SMRTER, contains Myb-like domains
KOG3579	Predicted E3 ubiquitin ligase
KOG4333	Nuclear DEAF-1 related transcriptional regulator (suppressin) and related SAND domain proteins
KOG4207	Predicted splicing factor, SR protein superfamily
KOG1554	COP9 signalosome, subunit CSN5
KOG1375	Beta tubulin

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG1036 - KOG1166	Bub3 - Bub1 Bub3 - BubR1	Bub3 - CG14030 Bub3 - Bub1	Y54G9A.6 - R06C7.8 Y54G9A.6 - ZC328.4
KOG0668 - KOG3092	CK2alpha - Casein Kinase Ii CK2-alpha' subunit - Casein Kinase Ii	CKII-alpha - CKII-beta	B0205.7 - T01G9.6
KOG0746 - KOG1628	RPL3 - LOC146053	DIP:17151N - RpS3A DIP:17151N - RpS3A RpL3 - RpS3A RpL3 - RpS3A	F13B10.2 - F56F3.5
KOG0746 - KOG4212	RPL3 - HNRPM	DIP:17151N - CG9373 RpL3 - CG9373	F13B10.2 - C25A1.4
KOG0746 - KOG0901	RPL3 - RPL23	DIP:17151N - RpL17A RpL3 - RpL17A	F13B10.2 - B0336.10
KOG0653 - KOG3484	Cyclin B1 - CKS1B cyclin B2 - CKS1B	DIP:17624N - CG9790 CycG - DIP:102N CycG - CG9790	DIP:24822N - C09G4.3 R02F2.1 - C09G4.3 H31G24.4 - C09G4.3
KOG1166 - KOG1588	BubR1 - KHDRBS1	Bub1 - DIP:17901N	ZC328.4 - E02D9.1 R06C7.8 - E02D9.1
KOG0830 - KOG1350	LAMR1 - ATP5B	sta - ATPsyn-beta	B0393.1 - C34E10.6
KOG0676 - KOG1350	ACTG1 - ATP5B ACTC - ATP5B	Act87E - ATPsyn-beta Act42A - ATPsyn-beta	Y53F4B.22 - C34E10.6
KOG0819 - KOG2309	ANXA2 - RPL8	AnnIX - RpL8	ZC155.1 - B0250.1
KOG1475 - KOG3544	RPL4 - COL4A1 RPL4 - COL6A3 RPL4 - COL6A1 RPL4 - COL5A2 RPL4 - COL1A1 RPL4 - COL6A2 RPL4 - COL12A1 RPL4 - COL5A1 RPL4 - COL1A2	RpL1 - vkg	B0041.4 - M01E10.2 B0041.4 - B0024.1 B0041.4 - C09G5.5
KOG2169 - KOG2294	PIAS1 - FoxO1 PIAS1 - FoxO3 PIAS1 - FoxO4	CG7958 - CG11799 DIP:18140N - CG11799	DIP:26255N - DAF-16
KOG0864 - KOG1074	RanBP2 - SALL1	CG11856 - CG2052	F59A2.1 - F15C11.1
KOG3528 - KOG3550	MAGI-1B - LIN-7B FIG - MAGI-1B FIG - LIN-7B	CG15617 - DIP:18367N Sip1 - scrib	Lin-10 - Lin-7
KOG3528 - KOG3528	PISP - NHERF2 Pals1-Associated Tight Junction Protein - Pals1-Associated Tight Junction Protein MAGI-1B - FIG FIG - MAGI-1B NHERF-2 - EBP50 Ezrin-Radixin-Moesin Binding Phosphoprotein 50 - EBP50 EBP50 - Ezrin-Radixin-Moesin Binding Phosphoprotein 50 EBP50 - NHERF2 EBP50 - NHERF-2 NHERF2 - EBP50 NHERF2 - PISP	CG14168 - INAD CG14168 - X11L CG15617 - DIP:18367N DIP:18367N - CG15617 Patj - Bazooka Sip1 - scrib scrib - Sip1 Bazooka - Bazooka Bazooka - Patj X11L - INAD X11L - CG14168 INAD - CG14168 INAD - X11L	ZK849.2 - F30F8.3 ZK849.2 - ZK849.2 ZK849.2 - DIP:26387N DIP:26387N - F30F8.3 DIP:26387N - DIP:26387N DIP:26387N - ZK849.2 F30F8.3 - DIP:26387N F30F8.3 - ZK849.2 Lin-10 - Lin-10
KOG0603 - KOG3529	Rsk3 - moesin Rsk3 - ezrin	CG30171 - Mer CG30171 - Moe	T01H8.1 - NFM-1
KOG3528 - KOG3529	Ezrin-Radixin-Moesin Binding Phosphoprotein 50 - moesin EBP50 - moesin EBP50 - Merlin EBP50 - radixin EBP50 - ezrin	CG6619 - Mer Patj - Mer Patj - Moe scrib - Moe scrib - Mer Bazooka - Mer	C01F6.6 - C01G8.5
KOG0580 - KOG4441	HsAIRK-2 - ENC1 HsAIRK-2 - KLHL1 HsAIRK-2 - FLJ33790	CG30171 - CG17754	K07C11.2 - DIP:25384N
KOG4441 - KOG4582	FLJ33790 - SQSTM1 KLHL1 - SQSTM1 ENC1 - SQSTM1	Keap1 - CG17492	DIP:25384N - DIP:24408N DIP:25384N - Y40C5A.1 DIP:25384N - C06G3.6 DIP:25384N - T12G3.1
KOG1704 - KOG3002	PINCH-2 - SIAH2 PINCH-2 - hSiah1	Lmpt - CG13030 Lmpt - sina stck - sina stck - CG13030 DIP:17600N - CG13030 DIP:17600N - sina DIP:18649N - CG13030 DIP:18649N - sina Pax - CG13030 Pax - sina	F28F5.3 - Y37E11AR.2
KOG1703 - KOG3681	PXN - VCL CLP-36 - CTNNA1 paxillin - vinculin	DIP:18649N - Vinc Pax - Vinc	EAT-1 - ZC477.9
KOG1703 - HG32204	PXN - GIT1 paxillin - GIT1	stck - CG16728 DIP:17600N - CG16728 CG30084 - cenG1A CG30084 - CG16728 DIP:17944N - CG16728	EAT-1 - F14F3.2
KOG1218 - KOG1703	FLJ90754 - ARA55	trol - stck trol - Pax BG:DS00180.10 - DIP:17944N BG:DS00180.10 - CG30084 BG:DS00180.10 - stck BG:DS00180.10 - DIP:17600N	Y64G10A.7 - Y65B4A.7
KOG1703 - KOG1704	FHL3 - FHL2 FHL3 - FHL1 paxillin - TES ARA55 - PINCH-2	stck - DIP:17600N stck - Lmpt DIP:17600N - Lmpt DIP:17600N - DIP:18649N DIP:17600N - Pax DIP:17600N - stck DIP:18649N - Pax DIP:18649N - DIP:17600N DIP:18649N - Lmpt Pax - DIP:18649N Pax - DIP:17600N Pax - Lmpt	EAT-1 - F28F5.3 C28H8.6 - F28F5.3
KOG1703 - KOG4211	paxillin - HNRPH3 paxillin - HNRPH1	DIP:17944N - CG6946 DIP:17944N - DIP:20250N	EAT-1 - Y73B6BL.33 EAT-1 - W02D3.11 C28H8.6 - Y73B6BL.33 C28H8.6 - W02D3.11
KOG1703 - KOG2272	PXN - paxillin ARA55 - paxillin	stck - DIP:17600N DIP:17600N - DIP:18649N DIP:17600N - Pax DIP:17600N - stck CG30084 - DIP:17944N DIP:17944N - CG30084 DIP:18649N - Pax DIP:18649N - DIP:17600N Pax - DIP:18649N Pax - DIP:17600N	Y65B4A.7 - unc-97 Y65B4A.7 - F14D12.2 EAT-1 - unc-97 EAT-1 - F14D12.2 C28H8.6 - unc-97 C28H8.6 - F14D12.2
KOG0940 - KOG1703	SMURF2 - ARA55 SMURF1 - CLP-36 SMURF1 - ARA55 SMURF1 - ARA55	CG7552 - CG32018 CG7552 - stck Nedd4 - stck	Y65B4BR.4 - EAT-1 F13E6.4 - EAT-1 F13E6.4 - C28H8.6
KOG1217 - KOG1588	FBN2 - KHDRBS1	DIP:17770N - qkr58E-1 CG7447 - DIP:17901N BG:DS00180.10 - qkr58E-1 BG:DS00180.10 - DIP:17901N CG9572 - qkr58E-1	R02F11.1 - E02D9.1
KOG1217 - KOG3528	KIAA0816 - KIAA1526	DIP:17770N - X11L DIP:17770N - INAD DIP:17770N - CG14168 DIP:17770N - Patj DIP:18444N - CG6688 DIP:18444N - INAD BG:DS00180.8 - CG6619 BG:DS00180.8 - DIP:18367N CG31999 - DIP:18367N CG31999 - scrib trol - X11L GI:24584298 - CG6619 GI:24648166 - scrib BG:DS00180.10 - CG6619 BG:DS00180.10 - CG14168 BG:DS00180.10 - X11L Crb - Dlt Crb - Bazooka Crb - Patj CG9572 - DIP:18367N	FBL-1 - ZK849.2 FBL-1 - F30F8.3 fbl-1 - DIP:26387N fbl-1 - F30F8.3 Y69H2.3A - ZK849.2 F58E6.3 - ZK849.2 F58E6.3 - DIP:26387N R02F11.1 - ZK849.2 R02F11.1 - DIP:26387N T06E6.10 - DIP:26387N T06E6.10 - ZK849.2
KOG1217 - KOG1218	FLJ14964 - FLJ90754 FLJ14964 - DKK1 DKFZP761E1824 - FLJ90754 fibulin-1A - FLJ90754	DIP:24016N - CG7526 CG12908 - GI:24584298 SP1070 - trol DIP:17770N - BG:DS00180.10 DIP:17770N - BG:DS00180.8 DIP:17770N - BG:DS00180.14 CG7447 - BG:DS00180.10 CG7447 - BG:DS00180.8 DIP:18444N - BG:DS00180.10 BG:DS00180.8 - BG:DS00180.10 BG:DS00180.8 - BG:DS00180.14 CG31999 - BG:DS00180.10 CG31999 - BG:DS00180.8 CG31999 - BG:DS00180.14 trol - sli GI:24584298 - CG12908 GI:24648166 - BG:DS00180.10 BG:DS00180.10 - BG:DS00180.8 BG:DS00180.10 - BG:DS00180.14 C901 - BG:DS00180.10 C901 - BG:DS00180.8 C901 - BG:DS00180.14 CG5639 - trol CG9572 - BG:DS00180.10 CG9572 - trol CG9572 - BG:DS00180.8 CG9572 - BG:DS00180.14 sli - trol	DIP:24487N - F48E3.8 F48E3.8 - DIP:24487N Y69H2.3A - Y64G10A.7 F58E6.3 - Y64G10A.7 R02F11.1 - Y64G10A.7
KOG0815 - KOG1217	RPLP0 - FLJ90754	RpP0 - DIP:17770N RpP0 - DIP:18444N RpP0 - CG9572 RpP0 - C901 RpP0 - BG:DS00180.10 RpP0 - trol	F25H2.10 - T06E6.10 F25H2.10 - fbl-1 F25H2.10 - Y38C1AA.9 F25H2.10 - FBL-1
KOG1217 - KOG2165	FBN2 - APC2	CG7447 - GI:20130331 DIP:18444N - GI:20130331	FBL-1 - K06H7.6 fbl-1 - K06H7.6 Y69H2.3A - K06H7.6 T06E6.10 - K06H7.6
KOG1217 - KOG2332	FLJ14964 - FTL	CG7447 - Fer1HCH CG7447 - Fer1HCH GI:24648166 - Fer1HCH GI:24648166 - Fer1HCH	FBL-1 - C54F6.14 fbl-1 - C54F6.14 Y69H2.3A - FTN-2 Y69H2.3A - C54F6.14 R02F11.1 - C54F6.14
KOG1217 - KOG2294	FLJ90754 - FoxO3 FLJ90754 - FoxH1 FLJ90754 - FoxO1 FLJ90754 - FoxO4 FBN2 - FoxH1 fibulin-1A - FoxO1 fibulin-1A - FoxO3 fibulin-1A - FoxO4	CG7447 - CG11799 trol - foxo BG:DS00180.10 - fd64A DIP:22303N - fd59A CG9572 - foxo	C08G9.2 - DAF-16
KOG1217 - KOG4582	FLJ90754 - SQSTM1 FBN2 - SQSTM1 fibulin-1A - SQSTM1	GI:24648166 - CG17492	FBL-1 - Y40C5A.1 fbl-1 - DIP:24408N F58E6.3 - C06G3.6 K08E5.3 - DIP:24408N K08E5.3 - Y40C5A.1
KOG1217 - KOG1703	FLJ90754 - ARA55 fibulin-1A - ARA55	SP1070 - Pax DIP:17770N - stck CG7447 - stck CG7447 - DIP:17600N DIP:18444N - DIP:17600N CG31999 - DIP:17944N CG31999 - CG30084 CG31999 - stck trol - stck trol - Pax BG:DS00180.10 - DIP:17944N BG:DS00180.10 - CG30084 BG:DS00180.10 - stck BG:DS00180.10 - DIP:17600N C901 - stck CG5639 - Pax CG9572 - DIP:17944N CG9572 - stck CG9572 - Pax CG9572 - CG32018 CG9572 - DIP:17600N CG9572 - CG30084	Y69H2.3A - Y65B4A.7 F58E6.3 - Y65B4A.7 F58E6.3 - EAT-1 R02F11.1 - Y65B4A.7 R02F11.1 - EAT-1
KOG1215 - KOG1217	LRP1 - fibulin-1A LRP1 - FLJ14964 LRP1 - FLJ90754 EGF - DIP:5762N LRP5 - FLJ14964	CG7526 - DIP:24016N CG12908 - GI:24584298 DIP:17306N - DIP:17770N DIP:18444N - BG:DS00180.10 DIP:18444N - DIP:17770N DIP:18444N - CG9572 DIP:18444N - C901 trol - sli trol - CG9572 trol - CG5639 trol - SP1070 CG12139 - trol CG12139 - sli CG8909 - trol CG8909 - CG9572	T21E3.3 - K07D8.1 T21E3.3 - K08E5.3 T04H1.6 - R02F11.1 T04H1.6 - T06E6.10
KOG0594 - KOG3575	CDC2 - ER-alpha CDC2 - DIP:1044N CDK4 - VDR CDK4 - ER-alpha CDK4 - RARB CDK4 - RXR-alpha CDK4 - GI:21322252 CDK6 - VDR CDK6 - RAR CDK6 - GI:21322252 CDK2 - VDR CDK2 - ER-alpha CDK2 - RARB CDK2 - RXR-alpha CDK2 - GI:21322252	CG30171 - ftz-f1	T05G5.3 - C08F8.8
KOG3575 - KOG3575	DIP:158N - RXR-alpha DIP:158N - VDR DIP:158N - NR1H4 DIP:158N - PPAR-alpha DIP:158N - RAR DIP:158N - PPARG PPAR-gamma-2 - LXR-alpha PPAR-gamma-2 - ER-alpha PPAR-gamma-2 - GI:21322252 PPAR-gamma-2 - ER-beta PPAR-gamma-2 - PPAR-alpha PPAR-gamma-2 - PPARG PPARG - RXR-alpha PPARG - PPARG PPARG - VDR PPARG - NR1H4 PPARG - DIP:158N PPARG - PPAR-alpha PPARG - RAR PPARG - ER-alpha PPARG - GI:21322252 PPARG - ER-beta PPARG - PPAR-gamma-2 RAR - RXR-alpha RAR - PPAR-alpha RAR - VDR RAR - ER-alpha RAR - GI:21322252 RAR - NR1H4 RAR - DIP:158N RAR - PPARG RAR - ER-beta DIP:622N - ER-alpha DIP:622N - ER-beta RXR-alpha - VDR RXR-alpha - RXR-alpha RXR-alpha - NR1H4 RXR-alpha - DIP:158N RXR-alpha - PPAR-alpha RXR-alpha - RAR RXR-alpha - PPARG RXR-alpha - ER-alpha RXR-alpha - GI:21322252 RXR-alpha - RARB RXR-alpha - ER-beta DIP:1044N - ER-alpha RARB - RXR-alpha ER-beta - ER-alpha ER-beta - DIP:622N ER-beta - RAR ER-beta - GI:21322252 ER-beta - PPAR-alpha ER-beta - PPARG ER-beta - PPAR-gamma-2 ER-beta - RXR-alpha VDR - VDR VDR - RXR-alpha VDR - RAR VDR - ER-alpha VDR - GI:21322252 VDR - NR1H4 VDR - DIP:158N VDR - PPAR-alpha VDR - PPARG PPAR-alpha - PPAR-alpha PPAR-alpha - RXR-alpha PPAR-alpha - RAR PPAR-alpha - ER-alpha PPAR-alpha - GI:21322252 PPAR-alpha - ER-beta PPAR-alpha - PPARG PPAR-alpha - PPAR-gamma-2 PPAR-alpha - VDR PPAR-alpha - NR1H4 PPAR-alpha - DIP:158N LXR-alpha - PPAR-gamma-2 RXR-beta - RXR-beta RXR-beta - ER-alpha CAR - ER-alpha GI:21322252 - ER-alpha GI:21322252 - VDR GI:21322252 - RXR-alpha GI:21322252 - RAR GI:21322252 - ER-beta GI:21322252 - PPAR-alpha GI:21322252 - PPARG GI:21322252 - PPAR-gamma-2 NR1H4 - RXR-alpha NR1H4 - VDR NR1H4 - DIP:158N NR1H4 - PPAR-alpha NR1H4 - RAR NR1H4 - PPARG ER-alpha - ER-alpha ER-alpha - DIP:622N ER-alpha - ER-beta ER-alpha - RAR ER-alpha - RXR-beta ER-alpha - LRH-1 ER-alpha - GI:21322252 ER-alpha - VDR ER-alpha - RXR-alpha ER-alpha - CAR ER-alpha - DIP:1044N ER-alpha - PPAR-alpha ER-alpha - PPARG ER-alpha - PPAR-gamma-2 PPARD - PPARD LRH-1 - ER-alpha	DIP:18899N - ftz-f1 Hr39 - tll ftz-f1 - DIP:18899N tll - Hr39 USP - USP	F58G6.5 - nhr-34 nhr-2 - C08F8.8 nhr-2 - F43C1.4 nhr-61 - nhr-4 C08F8.8 - nhr-2 C08F8.8 - F44G3.9 Y45G5AM.1 - F44G3.9 Y45G5AM.1 - R04B5.4 nhr-34 - F58G6.5 nhr-1 - R09G11.2 nhr-4 - nhr-61 nhr-4 - C26B2.3 Y80D3A.4 - C27C7.4 Y80D3A.4 - nhr-71 Y80D3A.4 - nhr-13 Y80D3A.4 - Y38E10A.18 Y80D3A.4 - NHR-22 Y80D3A.4 - ZK1037.5 Y80D3A.4 - ZK697.2 C26B2.3 - R04B5.4 C26B2.3 - nhr-13 C26B2.3 - F44G3.9 C26B2.3 - nhr-4 ZK697.2 - C27C7.4 ZK697.2 - nhr-71 ZK697.2 - nhr-13 ZK697.2 - Y38E10A.18 ZK697.2 - NHR-22 ZK697.2 - ZK1037.5 ZK697.2 - Y80D3A.4 ZK1037.5 - C27C7.4 ZK1037.5 - nhr-71 ZK1037.5 - nhr-13 ZK1037.5 - Y38E10A.18 ZK1037.5 - NHR-22 ZK1037.5 - ZK697.2 ZK1037.5 - Y80D3A.4 NHR-22 - C27C7.4 NHR-22 - nhr-71 NHR-22 - nhr-13 NHR-22 - Y38E10A.18 NHR-22 - ZK1037.5 NHR-22 - ZK697.2 NHR-22 - Y80D3A.4 NHR-22 - R04B5.4 C45E5.6 - F44G3.9 nhr-13 - C27C7.4 nhr-13 - nhr-71 nhr-13 - Y38E10A.18 nhr-13 - NHR-22 nhr-13 - ZK1037.5 nhr-13 - ZK697.2 nhr-13 - Y80D3A.4 nhr-13 - R04B5.4 nhr-13 - F44G3.9 nhr-13 - C26B2.3 F16B4.9 - T06C12.13 F16B4.9 - F44G3.9 nhr-71 - C27C7.4 nhr-71 - nhr-13 nhr-71 - Y38E10A.18 nhr-71 - NHR-22 nhr-71 - ZK1037.5 nhr-71 - ZK697.2 nhr-71 - Y80D3A.4 Y38E10A.18 - C27C7.4 Y38E10A.18 - nhr-71 Y38E10A.18 - nhr-13 Y38E10A.18 - NHR-22 Y38E10A.18 - ZK1037.5 Y38E10A.18 - ZK697.2 Y38E10A.18 - Y80D3A.4 F44G3.9 - F44G3.9 F44G3.9 - T06C12.13 F44G3.9 - F16B4.9 F44G3.9 - R04B5.4 F44G3.9 - nhr-13 F44G3.9 - C26B2.3 F44G3.9 - Y45G5AM.1 F44G3.9 - C45E5.6 F44G3.9 - C08F8.8 F44G3.9 - B0280.8 C11G6.4 - C33G8.6 F43C1.4 - nhr-2 R09G11.2 - nhr-1 B0280.8 - B0280.8 B0280.8 - F44G3.9 R04B5.4 - Y45G5AM.1 R04B5.4 - NHR-22 R04B5.4 - nhr-13 R04B5.4 - F44G3.9 R04B5.4 - C26B2.3 C33G8.6 - C11G6.4 C27C7.4 - nhr-71 C27C7.4 - nhr-13 C27C7.4 - Y38E10A.18 C27C7.4 - NHR-22 C27C7.4 - ZK1037.5 C27C7.4 - ZK697.2 C27C7.4 - Y80D3A.4 T06C12.13 - F44G3.9 T06C12.13 - F16B4.9
KOG0665 - KOG3575	JNK3alpha1 - ER-alpha JNK3alpha2 - ER-alpha JNK1beta1 - ER-alpha JNK1beta2 - ER-alpha JNK1alpha1 - ER-alpha JNK2alpha1 - ER-alpha JNK2alpha1 - GI:21322252 JNK2alpha2 - ER-alpha JNK2beta1 - ER-alpha JNK2beta2 - ER-alpha	CG30171 - ftz-f1	T07A9.3 - nhr-13 B0478.1 - nhr-13
KOG2012 - KOG3575	mop-4 - PPARD	Uba1 - ftz-f1	rfl-1 - F44G3.9
KOG1450 - KOG3575	ARHGAP9 - PPARD	DIP:17235N - Hr96	C38D4.5 - ZK488.4
KOG2165 - KOG3575	APC2 - RARB APC2 - RXR-alpha	GI:20130331 - tll	K06H7.6 - C08F8.8 K06H7.6 - H10E21.3 K06H7.6 - F44G3.9
KOG1219 - KOG3575	PCDH1 - VDR	sli - ftz-f1	ZC101.2E - F44G3.9
KOG2441 - KOG3575	SKIP - VDR	Bx42 - Hr96	T27F2.1 - F44G3.9
KOG0580 - KOG3575	STK6 - ER-alpha STK6 - DIP:1044N	CG30171 - ftz-f1	K07C11.2 - C08F8.8
KOG1217 - KOG3575	FLJ90754 - VDR FLJ14964 - PPARD FBN2 - RARB FBN2 - RXR-alpha	CG7447 - tll CG31999 - DIP:18899N trol - ftz-f1 GI:24648166 - ftz-f1 GI:24648166 - DIP:18899N sli - ftz-f1	FBL-1 - F44G3.9 FBL-1 - C45E5.6 FBL-1 - H10E21.3 Y38C1AA.9 - nhr-4 Y38C1AA.9 - C26B2.3 fbl-1 - H10E21.3 fbl-1 - F44G3.9 fbl-1 - C45E5.6 Y69H2.3A - F43C1.4 Y69H2.3A - H10E21.3 T10E10.4 - ZK488.4 K08E5.3 - R04B5.4 K08E5.3 - Y45G5AM.1 LIN-12 - R04B5.4 LIN-12 - NHR-22 R02F11.1 - K06B4.11 T06E6.10 - Y15E3A.1 T06E6.10 - K06B4.11
KOG1074 - KOG3575	FLJ20765 - PPARD ZF6 - PPARD	CG10274 - ftz-f1 CG10274 - DIP:18899N	F15C11.1 - nhr-13
KOG2462 - KOG3575	FLJ20765 - PPARD ZF6 - PPARD	CG10274 - ftz-f1 CG10274 - DIP:18899N esg - tll sna - tll	F43G9.11 - F44G3.9 F43G9.11 - C45E5.6 F43G9.11 - C08F8.8
KOG3575 - KOG3834	RXR-alpha - FLJ23443 RARB - FLJ23443 NR2F2 - FLJ23443	tll - CG7809	Y45G5AM.1 - DIP:26218N Y45G5AM.1 - Y42H9AR.1 C26B2.3 - DIP:26218N C26B2.3 - Y42H9AR.1 nhr-13 - DIP:26218N nhr-13 - Y42H9AR.1 F44G3.9 - DIP:26218N F44G3.9 - Y42H9AR.1 R04B5.4 - DIP:26218N R04B5.4 - Y42H9AR.1
KOG3575 - KOG3667	DIP:622N - STAT5a ER-beta - STAT5a ER-beta - STAT3 ER-alpha - STAT5a ER-alpha - Stat2 ER-alpha - STAT1-beta ER-alpha - STAT3	svp - Stat92E	C08F8.8 - Y51H4A.17
KOG3119 - KOG3575	HLF - ER-alpha	GI:17977662 - tll CG7786 - tll	K08F8.2 - nhr-13 K08F8.2 - Y15E3A.1 K08F8.2 - F44G3.9 K08F8.2 - Y45G5AM.1 K08F8.2 - R04B5.4 K08F8.2 - C26B2.3 D1005.3 - R04B5.4 D1005.3 - nhr-13 D1005.3 - F44G3.9 D1005.3 - C26B2.3 D1005.3 - Y45G5AM.1
KOG2330 - KOG3575	SF3b2 - VDR	CG3605 - tll	W03F9.10 - F44G3.9 W03F9.10 - Y45G5AM.1
KOG1892 - KOG3575	AF6 - RARB AF6 - RXR-alpha	cno - ftz-f1	W03F11.6 - R04B5.4 W03F11.6 - nhr-13 W03F11.6 - F44G3.9 W03F11.6 - C26B2.3 DIP:25922N - R04B5.4 DIP:25922N - nhr-13 DIP:25922N - F44G3.9 DIP:25922N - C26B2.3
KOG3002 - KOG3575	hSiah1 - NR2F2 SIAH2 - NR2F2	CG13030 - Hr96 CG13030 - DIP:18899N	Y37E11AR.2 - R04B5.4 Y37E11AR.2 - Y45G5AM.1 Y37E11AR.2 - F44G3.9 Y37E11AR.2 - C45E5.6 Y37E11AR.2 - B0280.8
KOG1215 - KOG3575	LRP5 - PPARD	trol - ftz-f1 CG12139 - ftz-f1	T04H1.6 - K06B4.11
KOG0586 - KOG0841	DIP:320N - 14-3-3-beta DIP:320N - 14-3-3-zeta DIP:320N - 14-3-3tau SIK2 - 14-3-3-beta	CG30171 - 14-3-3-epsilon	PAR-1 - PAR-5
KOG0841 - KOG2309	14-3-3-zeta - RPL8	14-3-3-epsilon - RpL8	ftt-2 - B0250.1 F52D10.3 - B0250.1
KOG0657 - KOG0841	GAPDH - 14-3-3-zeta	Gapdh2 - 14-3-3-epsilon	T09F3.3 - PAR-5
KOG0660 - KOG3575	Erk1 - ER-alpha ERK2 - ER-alpha p38-2 - ER-alpha	CG30171 - ftz-f1	B0218.3 - nhr-4 B0218.3 - C08F8.8 B0218.3 - nhr-61 B0218.3 - W01D2.2 MPK-1 - F44G3.9
KOG0660 - KOG0841	ERK2 - 14-3-3-beta ERK2 - 14-3-3-zeta ERK2 - 14-3-3tau p38-alpha - 14-3-3-zeta	CG30171 - 14-3-3-epsilon	MPK-1 - F52D10.3 MPK-1 - ftt-2
KOG2462 - KOG3701	FLJ20765 - Smad8 FLJ20765 - Smad2 IMAGE 3948563 - Smad1 IMAGE 3948563 - SMAD4 IMAGE 3948563 - Smad5 IMAGE 3948563 - Smad3 KIAA0972 - Smad1 KIAA0972 - SMAD4 KIAA0972 - Smad5 KIAA0972 - Smad3 ZF6 - Smad8 ZF6 - Smad2	esg - Smox	F43G9.11 - R13F6.9
KOG2272 - KOG3701	PINCH - SMAD4 PINCH - SMAD7 PINCH - Smad3 PINCH - Smad2 PINCH - Smad6 PINCH - Smad1 paxillin - Smad8 paxillin - SMAD4 paxillin - SMAD7 paxillin - Smad3 paxillin - Smad5 paxillin - Smad2	DIP:17600N - Smox CG30084 - Mad DIP:17944N - Mad DIP:18649N - Mad Pax - Mad	unc-97 - F25E2.5 unc-97 - sma-4 F14D12.2 - F25E2.5 F14D12.2 - sma-4
KOG3529 - KOG3701	Merlin - SMAD4 Merlin - Smad2 Merlin - Smad1	Mer - Smox Mer - Mad	C01G8.5 - R13F6.9
KOG3701 - KOG4297	Smad1 - FLJ90754 Smad2 - FLJ90754 Smad3 - FLJ90754 SMAD4 - FLJ90754	Mad - CG14499	R13F6.9 - Y38H6C.8 R13F6.9 - T05A7.3
KOG3701 - KOG3991	Smad2 - FLJ20113 Smad8 - FLJ20113	Mad - CG4968	R13F6.9 - C25D7.8
KOG3701 - KOG3780	Smad1 - TXNIP Smad2 - TXNIP Smad3 - TXNIP SMAD7 - TXNIP Smad6 - TXNIP Smad5 - TXNIP	Mad - CG2641	sma-4 - Y17G7B.14 sma-4 - R06B9.3 F25E2.5 - F48F7.7 F25E2.5 - Y17G7B.14 F25E2.5 - R06B9.3 R13F6.9 - ZK938.2
KOG1215 - KOG3701	LRP1 - SMAD4 LRP1 - Smad3 LRP1 - Smad2 LRP1 - Smad1 LRP5 - Smad8 LRP5 - Smad2	DIP:18444N - Smox	T04H1.6 - ZK370.2
KOG2260 - KOG3701	Cdc37 - Smad3 Cdc37 - Smad2	Cdc37 - Mad	W08F4.8 - R13F6.9 W08F4.8 - sma-4
KOG1700 - KOG3701	CRP2 - SMAD4 CRP2 - SMAD7 CRP2 - Smad1	Mlp84B - Mad DIP:17600N - Smox	B0496.7 - ZK370.2
KOG0660 - KOG3701	MAPK13 - SMAD4 MAPK13 - Smad5 MAPK13 - Smad3 MAPK13 - Smad2 MAPK13 - Smad1	CG32703 - Mad	B0218.3 - ZK370.2 B0218.3 - R13F6.9 MPK-1 - ZK370.2 MPK-1 - R13F6.9
KOG1703 - KOG3701	CLP-36 - SMAD4 paxillin - Smad8 paxillin - SMAD4 paxillin - SMAD7 paxillin - Smad3 paxillin - Smad5 paxillin - Smad2 ARA55 - SMAD4 ARA55 - Smad3 ARA55 - Smad5 ARA55 - Smad2 ARA55 - Smad1	DIP:17600N - Smox CG30084 - Mad DIP:17944N - Mad CG32018 - Smox DIP:18649N - Mad Pax - Mad	Y65B4A.7 - F25E2.5 Y65B4A.7 - sma-4 EAT-1 - sma-4 EAT-1 - F25E2.5 C34B2.4 - R13F6.9
KOG0841 - KOG3701	14-3-3tau - Smad8 14-3-3tau - Smad2	14-3-3-epsilon - Mad	ftt-2 - R13F6.9 F52D10.3 - R13F6.9
KOG1721 - KOG2330	PLZF - SF3b2 ZNF83 - SF3b2 PRDM4 - SF3b2 FLJ12586 - SF3b2 SIP1 - SF3b2 HIVEP1 - SF3b2 PLAGL1 - SF3b2 PLAG1 - SF3b2	odd - CG3605 bowl - CG3605 CG8159 - CG3605 D19A - CG3605 CG2116 - CG3605 CG10462 - CG3605 CG2889 - CG3605	F53B3.1 - W03F9.10 C27A12.2 - W03F9.10 F57C9.4 - W03F9.10
KOG1721 - KOG2294	PLZF - FoxO3 PLZF - FoxH1 PLZF - FoxO1 PLZF - FoxO4 ZNF83 - FoxO3 ZNF83 - FoxH1 ZNF83 - FoxO1 ZNF83 - FoxO4 PRDM4 - FoxO3 PRDM4 - FoxH1 PRDM4 - FoxO1 PRDM4 - FoxO4 FLJ12586 - FoxO3 FLJ12586 - FoxH1 FLJ12586 - FoxO1 FLJ12586 - FoxO4 SIP1 - FoxO3 SIP1 - FoxH1 SIP1 - FoxO1 SIP1 - FoxO4 HIVEP1 - FoxO3 HIVEP1 - FoxH1 HIVEP1 - FoxO1 HIVEP1 - FoxO4 PLAGL1 - FoxO3 PLAGL1 - FoxH1 PLAGL1 - FoxO1 PLAGL1 - FoxO4 PLAG1 - FoxO3 PLAG1 - FoxH1 PLAG1 - FoxO1 PLAG1 - FoxO4	opa - CG11799 opa - fd59A CG7752 - CG11799 Aef1 - foxo CG10654 - CG11799 D19B - jumu CG14451 - fd59A DIP:17332N - CG11799 DIP:17378N - fd59A GI:24653568 - CG11799 DIP:17897N - CG11799 CG6808 - fd59A CG15710 - fd64A CG10959 - CG11799 CG2129 - fd59A CG7987 - fd59A CG17801 - CG11799 CG11696 - fd64A CkIIalpha-i1 - fd64A l(2)35Ea - CG11799 CG2678 - fd59A CG9797 - fd59A CG9797 - CG11799 CG8301 - CG11799 CG8301 - fd59A Sry-beta - CG11799 CG1647 - fd64A CG4730 - CG11799 CG7928 - CG11799 CG7928 - fd59A CG7386 - fd59A CG10147 - jumu CG8145 - fd59A	F53B3.1 - T28H11.4
KOG1721 - KOG1973	IMAGE 3948563 - ING1L YY1 - p28ING5 YY1 - ING4 ZNF76 - ING1L SIP1 - ING1L Egr1 - p28ING5 Egr1 - ING4 KIAA0972 - ING1L	CG40145 - Bip2 opa - CG7379 CG10274 - CG7379 CG10267 - Bip2 CG17612 - Bip2 CG10543 - Bip2 MTF-1 - DIP:19186N MTF-1 - CG9293 CG4820 - CG6632 D19A - Bip2 D19A - CG7379 CG18476 - Bip2 su(Hw) - Bip2 DIP:19181N - DIP:19186N DIP:19181N - CG9293 CG10309 - Bip2 ken - Bip2 CG17568 - CG7379 CG10462 - Bip2 CG10462 - CG7379 EG:BACR42I17.11 - Bip2 CG2889 - Bip2 CG31365 - Bip2 CG4854 - Bip2 CG4936 - Bip2 Sry-delta - Bip2 CG7386 - Bip2 CG7386 - CG7379 CG10147 - Bip2 CG17806 - Bip2 CG11762 - Bip2 CG11798 - Bip2	EOR-1 - DIP:26104N
KOG1074 - KOG1721	FLJ20765 - E4F1 FLJ20765 - ZF6 FLJ20765 - SIP1 FLJ20765 - ZNF83 IMAGE 3948563 - SIP1 IMAGE 3948563 - KIAA0972 IMAGE 3948563 - ZNF76 KIAA0972 - IMAGE 3948563 KIAA0972 - SIP1 KIAA0972 - ZNF76 ZF6 - E4F1 ZF6 - SIP1 ZF6 - ZNF83 ZF6 - FLJ20765	CG10274 - CG7386 CG10274 - CG8159 CG10274 - CG17568 CG10274 - CG4360 CG10274 - CG4854 CG10274 - CG8388 CG10274 - CG8301 CG10274 - CG3032 CG10274 - CG18764 CG10274 - D19A CG10274 - drm CG10274 - CG10267 CG10274 - Aef1 CG10274 - CG17612 CG10274 - CG1233 CG10274 - DIP:121N CG10274 - DIP:17378N CG10274 - CG7928 CG10274 - CG3281 CG10274 - CG9797 CG10274 - l(2)35Ea CG10274 - CG11696 CG10274 - CG10959 CG10274 - CG17802 CG10274 - CG7204 CG10274 - Sry-beta CG10274 - sug CG10274 - CG7987 CG6254 - DIP:22012N CG6254 - CG17801 CG6254 - CG9797 CG6254 - DIP:17378N CG6254 - CG17802 CG3941 - l(2)35Ea CG3941 - CG9609 CG3941 - CG11696 CG3941 - rgr CG3941 - CG10147 CG3941 - CG8301 CG3941 - CG7386 CG3941 - DIP:17897N CG3941 - CG10309 CG3941 - CG18476 CG3941 - Phol CG3941 - CG10543 CG3941 - D19B CG3941 - CG10654 CG2052 - zfh1 CG2052 - DIP:18586N CG2052 - odd CG2052 - CG8388 CG2052 - wdn CG2052 - CG8301 CG2052 - CG10267 CG6808 - DIP:17378N CG6808 - CG9797 CG6808 - CG7928 CG6808 - CG2116 CG6808 - CG10267 CG6808 - opa CG6808 - Sry-beta CG31782 - CG9797 CG31782 - CG1792 CG31782 - CG7357 CG31782 - CG7386 CG31782 - CG8301 CG31782 - DIP:17897N CG31782 - D19A CG31782 - CG10654 crol - CG1832 crol - CG18262 crol - CG10543 crol - CG11971 crol - D19B crol - CG8301 crol - CG12391 crol - CG2202 crol - DIP:21597N crol - CG4820 crol - CG8319 crol - CG7386 crol - CG10654 DIP:20799N - CG8159 DIP:21597N - CG8301 DIP:21597N - CG12391 DIP:21597N - CG2202 DIP:21597N - crol DIP:21597N - CG8319 DIP:21597N - CG7386 DIP:21597N - CG7987 DIP:21597N - DIP:17897N DIP:21597N - CG4820 DIP:21597N - DIP:121N	F15C11.1 - C07A12.1
KOG1342 - KOG1721	Rpd3p - YY1 Rpd3p - DIP:36N HDAC2 - YY1 HDAC2 - PLZF HDAC2 - Sp1 HDAC2 - DIP:36N HDAC1 - PLZF HDAC1 - DIP:5990N HDAC1 - Miz-1 HDAC1 - AEBP2 HDAC1 - Sp1 HDAC3 - BCL6 HDAC3 - zid HDAC3 - PLZF	dHDAC1 - pho dHDAC1 - Phol	C53A5.3 - F53B3.1
KOG1704 - KOG1721	TES - ZNF510 PINCH-2 - ZFD25 FHL2 - ZNF36	Lmpt - sug Lmpt - CG7368 Lmpt - CG3032 Lmpt - CG17801 Lmpt - CG8145 stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) CG6522 - D19A CG6522 - CG11696 CG6522 - CG11695 CG6522 - su(Hw)	F28F5.3 - EOR-1 F28F5.3 - F54F2.5
KOG0660 - KOG1721	Erk1 - ZNF7 Erk1 - Sp1 Erk1 - YY1 p38-2 - YY1	p38b - Sry-beta p38b - CG8159 p38b - CG3281 p38b - CG17568 p38b - CG18764 p38b - CG10274 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	B0218.3 - ZK892.7 MPK-1 - ZK892.7 MPK-1 - F54F2.5
KOG1703 - KOG1721	paxillin - ZNF510 paxillin - CTCF ARA55 - PLAG1 ARA55 - HIVEP1 ARA55 - SIP1 ARA55 - ZNF83 ARA55 - FLJ12586 ARA55 - PLAGL1 ARA55 - PRDM4 ARA55 - PLZF ARA55 - ZFD25 PINCH-2 - ZFD25 DIP:5931N - DIP:5990N	stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 unc-115 - bowl DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 CG30084 - CG3281 CG30084 - CG7357 CG30084 - DIP:17378N CG30084 - CG18011 CG30084 - CG17801 CG30084 - CG10959 CG30084 - CG8159 DIP:17944N - CG3281 DIP:17944N - CG7357 DIP:17944N - DIP:17378N DIP:17944N - CG18011 DIP:17944N - CG17801 DIP:17944N - CG10959 DIP:17944N - CG8159 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) DIP:21964N - bowl	Y65B4A.7 - ZK892.7 EAT-1 - F54F2.5 EAT-1 - EOR-1 EAT-1 - ZK867.1 EAT-1 - DIP:24379N EAT-1 - R08E3.4 EAT-1 - C27A12.2 EAT-1 - T09F3.1 EAT-1 - Y54E10BR.8 C28H8.6 - F54F2.5
KOG0668 - KOG1721	CK2-alpha' subunit - OSR1	CKII-alpha - CG4820 CKII-alpha - opa CKII-alpha - CG10979 CKII-alpha - CG10654 CKII-alpha - CG8159 CKII-alpha - DIP:17897N CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	B0205.7 - F53F8.1
KOG0676 - KOG1721	ACTG1 - ZNF510 ACTG1 - HIVEP1 ACTG1 - zid ACTC - HIVEP1 ACTC - ZNF510	Arp87C - CG40145 Act87E - CG2678 Act87E - CG1647 Act87E - CG7386 Act87E - CG17801 Act87E - jing Act87E - CG7752 Act87E - CG7357 Act42A - CG33213 Act42A - sug Act42A - l(2)35Ea Act42A - opa Act42A - CG1792 Act42A - DIP:19658N Act42A - hkb Act42A - odd Act42A - CG8159 Act42A - CG17568 Act42A - CG18764 Arp11 - CG9797	T04C12.5 - F53B3.1 T04C12.5 - T09F3.1
KOG0940 - KOG1721	NEDD4 - IMAGE 3948563 NEDD4 - SIP1 NEDD4 - KIAA0972 NEDD4 - ZNF76 KIAA1301 - IMAGE 3948563 KIAA1301 - SIP1 KIAA1301 - KIAA0972 KIAA1301 - ZNF76 FLJ32109 - SIP1 SMURF2 - ZFD25 SMURF2 - ZNF-U69274 SMURF2 - PLAG1 SMURF2 - HIVEP1 SMURF2 - SIP1 SMURF2 - ZNF83 SMURF2 - FLJ12586 SMURF2 - PLAGL1 SMURF2 - PRDM4 SMURF2 - PLZF SMURF2 - IMAGE 3948563 SMURF2 - KIAA0972 SMURF2 - ZNF76 SMURF1 - ZFD25 SMURF1 - ZNF-U69274 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76	CG7552 - DIP:17332N CG7552 - GI:24653568 CG7552 - CG8301 CG7552 - odd CG7552 - CG10267 CG3003 - CG7928 CG3003 - CG9793 CG3099 - DIP:17378N CG3099 - CG6808 CG3099 - CG8319 CG3099 - CG17568 CG3099 - CG2116 CG3099 - CG18476 CG3099 - DIP:19928N CG3099 - CG33213 CG3099 - CG7357 CG3099 - CG9797 CG3099 - CG8301 Nedd4 - CG9817 Nedd4 - CG1832 Nedd4 - CG18262 Nedd4 - crol Nedd4 - CG10543 Nedd4 - CG11971 Nedd4 - D19B Su(dx) - DIP:17332N Su(dx) - CG4820 Su(dx) - GI:24653568	Y65B4BR.4 - ZK867.1 Y65B4BR.4 - DIP:24379N Y65B4BR.4 - F54F2.5 Y65B4BR.4 - R08E3.4 Y65B4BR.4 - C27A12.2 Y65B4BR.4 - T09F3.1 Y65B4BR.4 - Y54E10BR.8 Y65B4BR.4 - ZK892.7 F13E6.4 - ZK867.1 F13E6.4 - DIP:24379N F13E6.4 - F54F2.5 F13E6.4 - R08E3.4 F13E6.4 - C27A12.2 F13E6.4 - T09F3.1 F13E6.4 - Y54E10BR.8
KOG0749 - KOG1721	SLC25A5 - HIVEP1	DIP:19903N - pho Ant2 - CG18476 Ant2 - opa Ant2 - CG8301 Ant2 - DIP:17332N Ant2 - GI:24653568 Ant2 - CG7752 Ant2 - CG5245 Ant2 - CG8319 Ant2 - CG11247 Ant2 - CG10979	DIP:26442N - ZK867.1 DIP:26442N - DIP:24379N DIP:26442N - F54F2.5 DIP:26442N - R08E3.4 DIP:26442N - C27A12.2 DIP:26442N - T09F3.1 DIP:26442N - Y54E10BR.8 F25B4.7 - ZK867.1 F25B4.7 - DIP:24379N F25B4.7 - F54F2.5 F25B4.7 - R08E3.4 F25B4.7 - C27A12.2 F25B4.7 - T09F3.1 F25B4.7 - Y54E10BR.8 T27E9.1 - EOR-1
KOG0841 - KOG1721	14-3-3-epsilon - BCL6 14-3-3-epsilon - PLZF 14-3-3tau - E4F1 14-3-3tau - ZF6 14-3-3tau - SIP1 14-3-3tau - ZNF83 14-3-3tau - FLJ20765	14-3-3-epsilon - CG10979 14-3-3-epsilon - CG9797 14-3-3-epsilon - CG6808 14-3-3-epsilon - CG2889 14-3-3-epsilon - CG10267 14-3-3-epsilon - DIP:22690N 14-3-3-epsilon - EP2237 14-3-3-epsilon - Aef1 14-3-3-epsilon - Sqz	PAR-5 - F47H4.1 PAR-5 - F54H5.4 ftt-2 - F53B3.1 F52D10.3 - F53B3.1
KOG0581 - KOG1721	MEK2 - ZNF7 MEK1 - ZNF7	CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	MEK-2 - F54F2.5
KOG1217 - KOG1721	FLJ90754 - zid FLJ90754 - ZFP106 FLJ90754 - FLJ23392 FLJ90754 - ZNF36 FLJ90754 - PLAG1 FLJ90754 - HIVEP1 FLJ90754 - SIP1 FLJ90754 - ZNF83 FLJ90754 - FLJ12586 FLJ90754 - PLAGL1 FLJ90754 - PRDM4 FLJ90754 - PLZF FLJ14964 - zid FLJ14964 - ZFP106 FLJ14964 - FLJ23392 FLJ14964 - E4F1 FLJ14964 - ZF6 FLJ14964 - SIP1 FLJ14964 - ZNF83 FLJ14964 - FLJ20765 FBN2 - SIP1 LTBP3 - COASTER LTBP3 - RLF DKFZP761E1824 - zid fibulin-1A - zid fibulin-1A - ZFP106 fibulin-1A - FLJ23392	CG12908 - zfh1 CG12908 - CG8145 DIP:17306N - CG2678 DIP:17306N - CG10543 DIP:17306N - CG16779 DIP:17770N - DIP:19658N DIP:17770N - CG8319 DIP:17770N - CG8159 DIP:17770N - CG33213 DIP:17770N - zfh1 DIP:17770N - CG30431 DIP:17770N - CG1792 DIP:17770N - CG7963 DIP:17770N - CG8301 DIP:17770N - CG2116 DIP:17770N - CG10267 DIP:17770N - CG8484 DIP:17770N - CG2678 DIP:17770N - bowl DIP:17770N - CG17568 DIP:17770N - CG18476 DIP:17770N - DIP:19928N CG7447 - DIP:23226N CG7447 - CG8301 CG7447 - CkIIalpha-i1 CG7447 - D19A CG7447 - opa CG7447 - DIP:17332N CG7447 - GI:24653568 CG7447 - CG7752 CG7447 - DIP:19658N CG7447 - DIP:20799N DIP:18444N - DIP:17378N DIP:18444N - CG6808 DIP:18444N - zfh1 DIP:18444N - CG17801 DIP:18444N - CG8145 DIP:18444N - CG15336 DIP:18444N - D19A DIP:18444N - CG2678 DIP:18444N - CG17568 DIP:18444N - CG2116 DIP:18444N - CG18476 DIP:18444N - DIP:19928N DIP:18444N - CG33213 BG:DS00180.8 - DIP:19928N BG:DS00180.8 - CG4820 BG:DS00180.8 - odd BG:DS00180.8 - hkb BG:DS00180.8 - D19A BG:DS00180.8 - opa BG:DS00180.8 - DIP:19658N BG:DS00180.8 - CG7928 BG:DS00180.8 - bowl CG31999 - CG12701 CG31999 - zfh1 CG31999 - CG3281 CG31999 - CG7357 CG31999 - DIP:17378N CG31999 - CG18011 CG31999 - CG17801 CG31999 - CG10959 CG31999 - CG8159 CG31999 - CG33213 CG31999 - CG8301 CG31999 - CG8145 CG31999 - CG11798 CG31999 - CG17568 CG31999 - CG1792 CG31999 - CG7963 CG31999 - CG2116 CG31999 - CG10267 trol - CG10147 trol - CG11971 trol - CG1832 trol - CG18262 trol - crol trol - CG10543 trol - D19B trol - jing trol - CG7752 GI:24584298 - zfh1 GI:24584298 - CG8145 GI:24648166 - CG4730 GI:24648166 - CG7386 GI:24648166 - CG31365 BG:DS00180.10 - hkb BG:DS00180.10 - CG7386 BG:DS00180.10 - DIP:19658N BG:DS00180.10 - CG8319 BG:DS00180.10 - CG18262 BG:DS00180.10 - CG33213 BG:DS00180.10 - CG2116 BG:DS00180.10 - CG7928 BG:DS00180.10 - DIP:17378N BG:DS00180.10 - CG9797 BG:DS00180.10 - CG6808 BG:DS00180.10 - CG10267 BG:DS00180.10 - opa BG:DS00180.10 - CG2889 BG:DS00180.10 - CG4936 BG:DS00180.10 - l(2)35Ea BG:DS00180.10 - EG:95B7.7 BG:DS00180.10 - CG18764 BG:DS00180.10 - CG31365 BG:DS00180.10 - CG10654 BG:DS00180.10 - DIP:23226N BG:DS00180.10 - CG3281 BG:DS00180.10 - CG17568 BG:DS00180.10 - CG11696 BG:DS00180.10 - CG10959 BG:DS00180.10 - D19A BG:DS00180.10 - CG17802 BG:DS00180.10 - CG7204 BG:DS00180.10 - CG10274 BG:DS00180.10 - CG8301 BG:DS00180.10 - CG17801 BG:DS00180.10 - CG18476 BG:DS00180.10 - DIP:19928N BG:DS00180.10 - CG1792 BG:DS00180.10 - CG8159 BG:DS00180.10 - DIP:17897N BG:DS00180.10 - DIP:22012N BG:DS00180.10 - odd BG:DS00180.10 - CG32767 BG:DS00180.10 - CG11695 BG:DS00180.10 - CTCF BG:DS00180.10 - GI:24653568 BG:DS00180.10 - DIP:17332N C901 - CG17568 C901 - CG2116 C901 - CG18476 C901 - DIP:19928N C901 - CG33213 C901 - CG8301 C901 - CG4820 C901 - CG30431 DIP:22303N - CG6808 DIP:22303N - CG7928 Tld - CG2889 CG9572 - CG1792 CG9572 - DIP:19658N CG9572 - hkb CG9572 - odd CG9572 - CG8319 CG9572 - CG9797 CG9572 - CG18764 CG9572 - CG8301 CG9572 - DIP:22012N CG9572 - CG17568 CG9572 - CG2116 CG9572 - CG18476 CG9572 - DIP:19928N CG9572 - CG33213 CG9572 - CG7928 CG9572 - DIP:17378N CG9572 - CG6808 CG9572 - CG10267 CG9572 - opa CG9572 - DIP:18586N CG9572 - CG2052 CG9572 - DIP:23226N CG9572 - CG18262 CG9572 - CG4730 CG9572 - CG32767 CG9572 - CG10979 CG9572 - CG4820 CG9572 - CG11798 CG9572 - CG7963 CG9572 - CG7357 CG9572 - l(2)35Ea CG9572 - CG7386 CG9572 - DIP:17897N CG9572 - CG10654 CG9572 - D19A sli - jing sli - CG7752	FBL-1 - EOR-1 fbl-1 - EOR-1 K08E5.3 - C07A12.1
KOG1721 - KOG3544	FLJ23392 - COL4A2 ZFP106 - COL4A2 zid - COL4A2 ZNF510 - COL5A2 ZNF510 - COL12A1	odd - CG11349 CG8159 - vkg DIP:17378N - Cg25C CG4820 - CG11349 CG14711 - CG11349 CG2116 - Cg25C CG17568 - CG11349 CG8301 - Cg25C	DIP:24379N - M01E10.2 DIP:24379N - B0024.1 Y54E10BR.8 - M01E10.2 Y54E10BR.8 - B0024.1 F54H5.4 - B0024.1 F54H5.4 - C35B8.1 T09F3.1 - M01E10.2 T09F3.1 - B0024.1 F53B3.1 - Y11D7A.11 F47H4.1 - C35B8.1 C27A12.2 - M01E10.2 C27A12.2 - B0024.1 R08E3.4 - M01E10.2 R08E3.4 - B0024.1 R08E3.4 - T05A1.2 F54F2.5 - M01E10.2 F54F2.5 - B0024.1 F54F2.5 - ZK1193.1 F54F2.5 - col-19 F54F2.5 - F11G11.12 ZK892.7 - W05B2.5 ZK892.7 - C53B4.5 ZK867.1 - M01E10.2 ZK867.1 - B0024.1
KOG1721 - KOG1911	CTIP2 - HP1-alpha	CG10654 - HP1b CG10654 - rhi D19B - rhi CG17612 - Su(var)205 CG2052 - Su(var)205 DIP:17332N - HP1b GI:24653568 - HP1b CG4820 - HP1b D19A - rhi DIP:17897N - HP1b DIP:17897N - rhi CG18764 - HP1b CG31782 - rhi DIP:18586N - Su(var)205 CG14441 - rhi CG11696 - rhi CG17568 - HP1b CG17568 - rhi CG10321 - CG18186 CG10321 - rhi CG2678 - rhi CG9797 - rhi CG9797 - HP1b CG9797 - Su(var)205 CG8301 - HP1b CG8301 - rhi CG7928 - Su(var)205 CG7928 - CG15636 CG7386 - HP1b CG7386 - rhi CG7357 - Su(var)205 CG7357 - rhi CG10147 - CG8289 CG1792 - rhi CG1792 - Su(var)205	F37D6.2 - K08H2.6
KOG1721 - KOG4211	FLJ21628 - KIAA0682 HIVEP1 - HNRPH3 HIVEP1 - HNRPH1 ZNF510 - HNRPH3 ZNF510 - HNRPH1	CG4820 - DIP:23802N DIP:19658N - DIP:20250N DIP:19658N - CG6946 hkb - DIP:20250N hkb - CG6946 CG7386 - DIP:20250N CG7386 - CG6946	EOR-1 - Y73B6BL.33 EOR-1 - W02D3.11 F54F2.5 - Y73B6BL.33 F54F2.5 - W02D3.11
KOG1721 - KOG3002	ZFD25 - SIAH2 ZFD25 - hSiah1	opa - CG13030 opa - sina CG7752 - CG13030 CG33213 - CG13030 CG10267 - sina CG10267 - CG13030 CG10654 - CG13030 CG6254 - CG6688 D19B - sina odd - CG13030 CG8159 - sina CG8159 - CG13030 CG11971 - sina DIP:17332N - CG13030 DIP:17378N - CG13030 DIP:17378N - sina GI:24653568 - CG13030 CG10543 - sina DIP:17897N - CG13030 CG14711 - CG13030 CG18476 - CG13030 pho - CG13030 CG10959 - CG13030 CG10959 - sina CG7987 - sina crol - sina CG17801 - CG13030 CG17801 - sina CG2116 - CG13030 CG2116 - sina CG18262 - sina CG11696 - CG13030 CG11696 - sina CG17568 - CG13030 CG2889 - sina CG2889 - CG13030 l(2)35Ea - CG13030 CG31365 - CG13030 CG2678 - CG13030 CG2678 - sina CG18011 - CG13030 CG18011 - sina CG9797 - CG13030 DIP:22012N - CG6688 CG8301 - CG13030 CG8301 - sina CG3281 - CG13030 CG3281 - sina CG4730 - CG13030 CG7928 - CG13030 CG7386 - CG13030 CG7357 - CG13030 CG7357 - sina CG1832 - sina CG8319 - CG13030	EOR-1 - Y37E11AR.2 C07A12.1 - Y37E11AR.2
KOG1721 - KOG3834	ZFD25 - FLJ23443	opa - CG7809 CG33213 - CG7809 CG10267 - CG7809 odd - CG7809 DIP:17378N - CG7809 D19A - CG7809 CG18476 - CG7809 DIP:19658N - CG7809 DIP:19928N - CG7809 CG2116 - CG7809 CG17568 - CG7809 CG9797 - CG7809 CG8301 - CG7809 hkb - CG7809 CG7357 - CG7809 CG11798 - CG7809	DIP:24379N - DIP:26218N DIP:24379N - Y42H9AR.1 Y54E10BR.8 - DIP:26218N Y54E10BR.8 - Y42H9AR.1 T09F3.1 - DIP:26218N T09F3.1 - Y42H9AR.1 C07A12.1 - DIP:26218N C07A12.1 - Y42H9AR.1 C27A12.2 - DIP:26218N C27A12.2 - Y42H9AR.1 R08E3.4 - DIP:26218N R08E3.4 - Y42H9AR.1 F54F2.5 - DIP:26218N F54F2.5 - Y42H9AR.1 ZK892.7 - Y42H9AR.1 ZK892.7 - DIP:26218N ZK867.1 - DIP:26218N ZK867.1 - Y42H9AR.1
KOG1721 - KOG1892	SIP1 - AF6	CG7752 - cno CG16779 - cno jing - cno CG2678 - cno CG11798 - cno CG11798 - cno	DIP:24379N - DIP:25922N DIP:24379N - W03F11.6 Y54E10BR.8 - DIP:25922N Y54E10BR.8 - W03F11.6 T09F3.1 - DIP:25922N T09F3.1 - W03F11.6 C07A12.1 - DIP:25922N C07A12.1 - W03F11.6 C27A12.2 - DIP:25922N C27A12.2 - W03F11.6 R08E3.4 - DIP:25922N R08E3.4 - W03F11.6 F54F2.5 - DIP:25922N F54F2.5 - W03F11.6 ZK867.1 - DIP:25922N ZK867.1 - W03F11.6
KOG1721 - KOG1923	COASTER - KIAA1902 RLF - KIAA1902	wdn - CG13913 CG33213 - CG13913 CG10979 - CG13913 odd - CG13913 CG8159 - CG13913 DIP:17378N - CG13913 CG10543 - CG13913 D19A - CG13913 CG18764 - CG13913 CG18476 - CG13913 CG10959 - CG13913 su(Hw) - CG13913 CG10309 - CG13913 CG17801 - CG13913 CG4360 - CG13913 EG:BACR42I17.11 - CG13913 l(2)35Ea - CG13913 CG18011 - CG13913 CG4854 - CG13913 CG4936 - CG13913 Sry-delta - CG13913 CG3281 - CG13913 CG7357 - CG13913 CG10147 - CG13913 CG11798 - CG13913	C07A12.1 - K01B6.1
KOG1721 - KOG4228	FLJ23392 - PTPRF ZFP106 - PTPRF TIEG - PTPRF zid - PTPRF COASTER - PTPRF RLF - PTPRF ZNF510 - PTPRE	CG7752 - CG30171 CG10267 - Robo CG11247 - Ptp4E D19B - CG30171 CG2052 - Robo CG11971 - CG30171 CG10543 - CG30171 CG10543 - CG30171 D19A - Ptp61F D19A - CG30171 CG18476 - CG30171 DIP:18586N - Robo su(Hw) - CG30171 crol - CG30171 CG10309 - CG30171 CG18262 - CG30171 EG:BACR42I17.11 - CG30171 jing - CG30171 CG8301 - Robo CG4936 - CG30171 Sry-delta - CG30171 CG7386 - DIP:21338N CG10147 - CG30171 CG1832 - CG30171 CG11798 - CG30171 CG11798 - Robo	F54F2.5 - F56D1.2
KOG1721 - KOG3606	OSR1 - PARD6A	CG4820 - par-6 CG15710 - par-6 CG17801 - par-6 CG17568 - par-6 CG1647 - par-6 CG7386 - par-6	EOR-1 - T26E3.3 F53B3.1 - T26E3.3
KOG1721 - KOG4441	OSR1 - ENC1 OSR1 - KLHL1 OSR1 - FLJ33790	opa - CG9426 CG7752 - CG17754 CG10267 - CG9426 CG10267 - CG3962 odd - CG9426 CG2052 - CG9426 CG8159 - CG9426 DIP:17378N - CG9426 CG10543 - CG9426 MTF-1 - CG9426 D19A - CG9426 CG6808 - CG9426 CG6808 - CG3962 CG14711 - CG9426 CG18764 - CG9426 DIP:18586N - CG9426 CG7987 - DIP:23449N CG7987 - CG3571 DIP:19181N - CG9426 CG17803 - CG9426 CG2116 - CG9426 CG15336 - CG9426 CG2889 - CG3962 CG2889 - CG9426 l(2)35Ea - CG9426 jing - CG17754 CG2678 - CG9426 CG9797 - CG9426 CG9797 - kel Sry-beta - CG9426 CTCF - CG9426 CG3281 - CG9426 CG7928 - CG9426 CG7386 - CG9426 CG10147 - CG9426 CG11798 - CG9426 CG8388 - CG9426	C07A12.1 - DIP:25384N ZK892.7 - DIP:25384N
KOG1721 - KOG3070	CTCF - YB-1 ZNF510 - YB-1	odd - yps CG8159 - yps CG2889 - yps CG12701 - yps	F54F2.5 - F46F11.2
KOG1721 - KOG2373	MGC4054 - FLJ21832 SIP1 - FLJ21832	crol - CG5924 CG10543 - CG5924	C27A12.2 - F46G11.1
KOG1721 - KOG1878	FLJ23392 - SMRT Miz-1 - NCOR2 PLZF - SMRT ZFP106 - SMRT zid - SMRT DIP:5990N - NCOR2 BCL6 - SMRT Sp1 - SMRT	CG16779 - Smr CG2678 - Smr	F54F2.5 - C14B9.6 F54F2.5 - gei-8
KOG1721 - KOG3667	YY1 - Stat2 YY1 - STAT1-beta Miz-1 - STAT5a ZNF7 - STAT5a Egr1 - Stat2 Egr1 - STAT1-beta DIP:5990N - STAT5a	CG10979 - Stat92E D19A - Stat92E su(Hw) - Stat92E CG9609 - Stat92E CG31365 - Stat92E CG7386 - Stat92E CG10147 - Stat92E	F54F2.5 - Y51H4A.17
KOG1721 - KOG3119	YY1 - C/EBP-gamma YY1 - CHOP Egr1 - C/EBP-gamma Egr1 - CHOP Egr1 - DDIT3	CG8159 - GI:17977662 DIP:17378N - GI:17977662 D19A - CG7786 CG6808 - CG7786 CG10959 - GI:17977662 CG17801 - GI:17977662 GI:17647565 - GI:17977662 CG10348 - GI:17977662 CG18011 - GI:17977662 CG9797 - CG7786 CG9797 - GI:17977662 sug - GI:17977662 CG3281 - GI:17977662 CG7928 - GI:17977662 CG7357 - GI:17977662	DIP:24379N - D1005.3 DIP:24379N - K08F8.2 Y54E10BR.8 - D1005.3 Y54E10BR.8 - K08F8.2 T09F3.1 - D1005.3 T09F3.1 - K08F8.2 T22C8.3 - ZK909.4 T22C8.3 - Y51H4A.4 T22C8.3 - K08F8.2 F53B3.1 - D1005.3 F53B3.1 - K08F8.2 C07A12.1 - K08F8.2 C27A12.2 - D1005.3 C27A12.2 - K08F8.2 F53F8.1 - K08F8.2 R08E3.4 - D1005.3 R08E3.4 - K08F8.2 F54F2.5 - D1005.3 F54F2.5 - K08F8.2 ZK867.1 - D1005.3 ZK867.1 - K08F8.2 F57C9.4 - D1005.3 F57C9.4 - K08F8.2
KOG1721 - KOG3579	IMAGE 3948563 - FLJ32368 ZNF76 - FLJ32368 SIP1 - FLJ32368 KIAA0972 - FLJ32368	opa - CG11138 opa - DIP:17993N Aef1 - CG11138 Aef1 - DIP:17993N odd - DIP:17993N odd - CG11138 CG2052 - DIP:17993N CG2052 - CG11138 DIP:17378N - CG11138 DIP:17378N - DIP:17993N D19A - CG11138 D19A - DIP:17993N CG18764 - CG11138 CG18764 - DIP:17993N DIP:18586N - DIP:17993N DIP:18586N - CG11138 DIP:19658N - DIP:17993N CG31365 - CG11138 CG31365 - DIP:17993N CG2678 - CG11138 CG2678 - DIP:17993N hkb - DIP:17993N hkb - CG11138 CG7386 - DIP:17993N CG7386 - CG11138 CG7357 - CG11138 CG7357 - DIP:17993N zfh1 - DIP:17993N zfh1 - CG11138 CG8319 - CG11138 CG8319 - DIP:17993N	DIP:24379N - M04G12.1 DIP:24379N - DIP:25625N EOR-1 - M04G12.1 EOR-1 - DIP:25625N Y54E10BR.8 - M04G12.1 Y54E10BR.8 - DIP:25625N T09F3.1 - M04G12.1 T09F3.1 - DIP:25625N F53B3.1 - DIP:25625N F53B3.1 - M04G12.1 C07A12.1 - M04G12.1 C07A12.1 - DIP:25625N C27A12.2 - DIP:25625N C27A12.2 - M04G12.1 R08E3.4 - M04G12.1 R08E3.4 - DIP:25625N F54F2.5 - M04G12.1 F54F2.5 - DIP:25625N ZK867.1 - M04G12.1 ZK867.1 - DIP:25625N F57C9.4 - DIP:25625N F57C9.4 - M04G12.1
KOG1721 - KOG4333	IMAGE 3948563 - GMEB1 PLZF - GMEB1 ZNF76 - GMEB1 ZNF83 - GMEB1 zid - GMEB1 PRDM4 - GMEB1 FLJ12586 - GMEB1 COASTER - GMEB1 SIP1 - GMEB1 KIAA0972 - GMEB1 HIVEP1 - GMEB1 PLAGL1 - GMEB1 PLAG1 - GMEB1	wdn - Deaf1 CG10979 - Deaf1 CG11247 - Deaf1 CG8159 - Deaf1 DIP:17378N - Deaf1 CG10959 - Deaf1 CG17801 - Deaf1 EG:95B7.7 - Deaf1 CG18011 - Deaf1 CG3281 - Deaf1 CG7357 - Deaf1	T09F3.1 - C25G4.4 F53B3.1 - C25G4.4
KOG1721 - KOG4582	IMAGE 3948563 - SQSTM1 PLZF - SQSTM1 ZNF76 - SQSTM1 ZNF83 - SQSTM1 PRDM4 - SQSTM1 FLJ12586 - SQSTM1 OSR1 - SQSTM1 SIP1 - SQSTM1 KIAA0972 - SQSTM1 HIVEP1 - SQSTM1 PLAGL1 - SQSTM1 PLAG1 - SQSTM1	CG33213 - ref(2)P CG7987 - ref(2)P CG2678 - ref(2)P Sqz - DIP:23847N CG11762 - CG17492 CG14962 - ref(2)P	EOR-1 - Y40C5A.1 EOR-1 - DIP:24408N F53B3.1 - DIP:24408N F53B3.1 - C06G3.6 F53B3.1 - Y40C5A.1 C07A12.1 - DIP:24408N C07A12.1 - Y40C5A.1 C27A12.2 - DIP:24408N C27A12.2 - C06G3.6 C27A12.2 - Y40C5A.1 F54F2.5 - C06G3.6 F54F2.5 - DIP:24408N F54F2.5 - Y40C5A.1 ZK867.1 - C06G3.6 F57C9.4 - DIP:24408N F57C9.4 - C06G3.6 F57C9.4 - Y40C5A.1
KOG1721 - KOG4207	FLJ21628 - KIAA0682	opa - SC35 CG7752 - SC35 Aef1 - DIP:17430N Aef1 - SC35 DIP:17332N - SC35 GI:24653568 - SC35 CG6808 - SC35 CG8301 - SC35 CG7928 - SC35	F54F2.5 - EEED8.7
KOG1721 - KOG2332	FLJ20765 - FTL ZNF83 - FTL SIP1 - FTL ZF6 - FTL E4F1 - FTL	opa - Fer1HCH opa - Fer1HCH CG7752 - Fer1HCH CG7752 - Fer1HCH CG10979 - CG4349 DIP:17332N - Fer1HCH DIP:17332N - Fer1HCH GI:24653568 - Fer1HCH GI:24653568 - Fer1HCH CG4820 - CG4349 CG18764 - Fer2LCH CG8301 - Fer1HCH CG8301 - Fer1HCH	T09F3.1 - FTN-2 F53B3.1 - FTN-2
KOG1721 - KOG3575	DIP:36N - VDR FLJ20765 - PPARD YY1 - ER-alpha YY1 - DIP:1044N YY1 - VDR Miz-1 - ER-alpha Miz-1 - ER-beta Miz-1 - DIP:622N PLZF - ER-alpha PLZF - PPARD PLZF - VDR PLZF - ER-beta PLZF - RAR ZNF83 - PPARD ZNF83 - VDR zid - PPARD zid - ER-alpha CTCF - RXR-beta PRDM4 - VDR FLJ12586 - VDR SIP1 - PPARD SIP1 - VDR SIP1 - RARB SIP1 - RXR-alpha Egr1 - ER-beta Egr1 - RAR Egr1 - ER-alpha DIP:5990N - ER-alpha DIP:5990N - DIP:622N DIP:5990N - ER-beta DIP:5990N - DIP:5999N DIP:5990N - RXR-beta ZF6 - PPARD ZFD25 - NR2F2 HIVEP1 - VDR E4F1 - PPARD BCL6 - PPARD BCL6 - ER-alpha PLAGL1 - VDR Sp1 - ER-beta Sp1 - RAR Sp1 - ER-alpha Sp1 - RXR-alpha PLAG1 - VDR	opa - Hr39 opa - DIP:18899N opa - ftz-f1 CG10274 - ftz-f1 CG10274 - DIP:18899N CG7752 - ftz-f1 D19A - svp D19A - tll su(Hw) - svp CG7987 - DIP:18899N CG7987 - ftz-f1 CG17801 - Hr96 GI:17647565 - tll DIP:19928N - DIP:18899N CG10348 - ftz-f1 CG10348 - Hr96 CG10348 - DIP:18899N CG10348 - tll CG17568 - DIP:18899N CG17568 - ftz-f1 CG9609 - svp l(2)35Ea - DIP:18899N l(2)35Ea - ftz-f1 jing - ftz-f1 sug - DIP:18899N sug - tll sug - ftz-f1 CG1647 - Hr96 CG4730 - ftz-f1 CG4730 - DIP:18899N CG7386 - Hr96 CG10147 - svp CG8145 - Hr96 CG8145 - Hr39 CG11762 - Hr39	DIP:24379N - Y15E3A.1 DIP:24379N - R04B5.4 DIP:24379N - nhr-13 DIP:24379N - F44G3.9 DIP:24379N - C26B2.3 EOR-1 - F44G3.9 EOR-1 - C45E5.6 Y54E10BR.8 - R04B5.4 Y54E10BR.8 - nhr-13 Y54E10BR.8 - F44G3.9 Y54E10BR.8 - C26B2.3 F54H5.4 - F44C8.11 F54H5.4 - nhr-2 T09F3.1 - R04B5.4 T09F3.1 - nhr-13 T09F3.1 - F44G3.9 T09F3.1 - C26B2.3 T22C8.3 - F44G3.9 F53B3.1 - F44G3.9 F53B3.1 - Y45G5AM.1 C07A12.1 - Y15E3A.1 C07A12.1 - R04B5.4 C07A12.1 - Y45G5AM.1 C07A12.1 - nhr-13 F47H4.1 - nhr-2 C27A12.2 - F44G3.9 C27A12.2 - Y45G5AM.1 C27A12.2 - R04B5.4 C27A12.2 - nhr-13 C27A12.2 - C26B2.3 R08E3.4 - R04B5.4 R08E3.4 - nhr-13 R08E3.4 - F44G3.9 R08E3.4 - C26B2.3 F54F2.5 - F44G3.9 F54F2.5 - R04B5.4 F54F2.5 - nhr-13 F54F2.5 - C26B2.3 ZK892.7 - F44G3.9 ZK867.1 - Y15E3A.1 ZK867.1 - F44G3.9 ZK867.1 - R04B5.4 ZK867.1 - nhr-13 ZK867.1 - C26B2.3 F57C9.4 - F44G3.9 F57C9.4 - Y45G5AM.1 C46E10.9 - C26B2.3
KOG1721 - KOG3701	ZNF-U69274 - SMAD7 FLJ20765 - Smad8 FLJ20765 - Smad2 FLJ21628 - Smad5 FLJ23392 - SMAD4 FLJ23392 - Smad3 FLJ23392 - Smad2 FLJ23392 - Smad1 TIZ - Smad8 TIZ - Smad8a IMAGE 3948563 - Smad1 IMAGE 3948563 - SMAD4 IMAGE 3948563 - Smad5 IMAGE 3948563 - Smad3 YY1 - Smad3 YY1 - Smad2 PLZF - Smad3 PLZF - SMAD4 PLZF - Smad2 PLZF - Smad1 ZFP106 - SMAD4 ZFP106 - Smad3 ZFP106 - Smad2 ZFP106 - Smad1 ZNF76 - Smad1 ZNF76 - SMAD4 ZNF76 - Smad5 ZNF76 - Smad3 TIEG - Smad1 MGC4054 - Smad8a ZNF83 - Smad8 ZNF83 - Smad3 ZNF83 - Smad2 ZNF83 - SMAD4 ZNF83 - Smad1 zid - SMAD4 zid - Smad3 zid - Smad2 zid - Smad1 PRDM4 - Smad3 PRDM4 - SMAD4 PRDM4 - Smad2 PRDM4 - Smad1 FLJ12586 - Smad3 FLJ12586 - SMAD4 FLJ12586 - Smad2 FLJ12586 - Smad1 OSR1 - SMAD4 OSR1 - SMAD7 OSR1 - Smad3 OSR1 - Smad2 COASTER - SMAD4 SIP1 - Smad8 SIP1 - Smad3 SIP1 - Smad8a SIP1 - Smad2 SIP1 - Smad1 SIP1 - SMAD4 SIP1 - Smad5 Egr1 - Smad3 Egr1 - Smad2 Egr1 - SMAD4 ZNF36 - Smad3 ZNF36 - Smad2 KIAA0972 - Smad1 KIAA0972 - SMAD4 KIAA0972 - Smad5 KIAA0972 - Smad3 ZF6 - Smad8 ZF6 - Smad2 ZFD25 - SMAD7 HIVEP1 - Smad3 HIVEP1 - SMAD4 HIVEP1 - Smad2 HIVEP1 - Smad1 E4F1 - Smad8 E4F1 - Smad2 RLF - SMAD4 BCL6 - Smad8 PLAGL1 - Smad3 PLAGL1 - SMAD4 PLAGL1 - Smad2 PLAGL1 - Smad1 Sp1 - SMAD4 Sp1 - Smad3 Sp1 - Smad2 PLAG1 - Smad3 PLAG1 - SMAD4 PLAG1 - Smad2 PLAG1 - Smad1	wdn - Mad CG2052 - Dad CG2052 - Mad CG6808 - Mad DIP:18586N - Dad DIP:18586N - Mad CG17801 - Smox CG9797 - Mad CG7386 - DIP:21819N CG7386 - Med CG7357 - Mad CG8145 - Smox CG11798 - Smox	R08E3.4 - ZK370.2
KOG0901 - KOG1721	RPL23 - ZNF510	RpL17A - btd RpL17A - CG7386 RpL17A - CG8301 RpL17A - CG17568 RpL17A - CG10654 RpL17A - zfh1 RpL17A - DIP:17897N RpL17A - DIP:18586N RpL17A - CG2052 RpL17A - DIP:17378N	B0336.10 - F57C9.4 B0336.10 - C27A12.2 B0336.10 - F53B3.1
KOG1554 - KOG1721	Jab1 - SIP1	CSN5 - CG2116	CSN-5 - R08E3.4
KOG0830 - KOG1721	LAMR1 - HIVEP1 AAK69721 - ZNF510	sta - CG12701 sta - odd	B0393.1 - EOR-1
KOG1375 - KOG1721	TUBB2 - HIVEP1	DIP:17391N - CG7357 DIP:17391N - CG9797 DIP:17391N - CG2116 DIP:17391N - DIP:17332N DIP:17391N - CG4820 DIP:17391N - GI:24653568 DIP:17391N - CG7386 DIP:17391N - CG11902 DIP:17391N - CG11696 DIP:17391N - Sry-beta DIP:17391N - CG1792 DIP:17391N - CG8301 DIP:17391N - DIP:17897N DIP:17391N - CG31782 DIP:17391N - D19A DIP:17391N - CG10654 DIP:17391N - odd DIP:17391N - l(2)35Ea DIP:17391N - CG10462 DIP:17391N - CG17568 DIP:17391N - CG4360 DIP:17391N - CG4854 DIP:17391N - CG8388 DIP:17391N - CG3032 DIP:17391N - CG18764 DIP:17391N - drm DIP:17391N - CG10267 DIP:17391N - Aef1 DIP:17391N - CG10274 DIP:17391N - CG11695 DIP:17391N - EG:BACR42I17.11 DIP:17391N - Sry-delta DIP:17391N - CG10147 DIP:17391N - CG11798 DIP:17391N - CG4936 DIP:17391N - CG10309 DIP:17391N - su(Hw) DIP:17391N - CG18476 DIP:17391N - CG10543 DIP:17391N - CG1603 DIP:17391N - CG2129 DIP:17391N - CG10979 DIP:17391N - CG12391 DIP:17391N - CG2202 DIP:17391N - crol DIP:17391N - DIP:21597N DIP:17391N - DIP:17378N DIP:17391N - CG14711 DIP:17391N - jim DIP:17391N - CG8159 betaTub56D - CG7357 betaTub56D - CG9797 betaTub56D - CG2116 betaTub56D - DIP:17332N betaTub56D - CG4820 betaTub56D - GI:24653568 betaTub56D - CG7386 betaTub56D - CG11902 betaTub56D - CG11696 betaTub56D - Sry-beta betaTub56D - CG1792 betaTub56D - CG8301 betaTub56D - DIP:17897N betaTub56D - CG31782 betaTub56D - D19A betaTub56D - CG10654 betaTub56D - odd betaTub56D - l(2)35Ea betaTub56D - CG10462 betaTub56D - CG17568 betaTub56D - CG4360 betaTub56D - CG4854 betaTub56D - CG8388 betaTub56D - CG3032 betaTub56D - CG18764 betaTub56D - drm betaTub56D - CG10267 betaTub56D - Aef1 betaTub56D - CG10274 betaTub56D - CG11695 betaTub56D - EG:BACR42I17.11 betaTub56D - Sry-delta betaTub56D - CG10147 betaTub56D - CG11798 betaTub56D - CG4936 betaTub56D - CG10309 betaTub56D - su(Hw) betaTub56D - CG18476 betaTub56D - CG10543 betaTub56D - CG1603 betaTub56D - CG14711 betaTub56D - jim betaTub56D - CG2129 betaTub56D - CG10979 betaTub56D - CG12391 betaTub56D - CG2202 betaTub56D - crol betaTub56D - DIP:21597N betaTub56D - DIP:17378N betaTub56D - CG8159	K01G5.7 - F53B3.1 K01G5.7 - T09F3.1
KOG1721 - KOG3484	KLF6 - CKS1B	opa - CG9790 sug - DIP:102N sug - CG9790 Sqz - CG9790 zfh1 - CG9790	ZK892.7 - Y71G12B.27

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Conserved subnet 2:
81 conserved interactions between 66 ortholog groups.
This subnet exists in 3 organisms (p<3e-152).

Ortholog Groups
KOG2169	Zn-finger transcription factor
KOG2294	Transcription factor of the Forkhead/HNF3 family
KOG2462	C2H2-type Zn-finger protein
KOG4203	Armadillo/beta-Catenin/plakoglobin
KOG2652	RNA polymerase II transcription initiation factor TFIIA, large chain
KOG3463	Transcription initiation factor IIA, gamma subunit
KOG1142	Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA)
KOG3334	Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)
KOG2549	Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA)
KOG3302	TATA-box binding protein (TBP), component of TFIID and TFIIIB
KOG1472	Histone acetyltransferase SAGA/ADA, catalytic subunit PCAF/GCN5 and related proteins
KOG1342	Histone deacetylase complex, catalytic component RPD3
KOG0837	Transcriptional activator of the JUN family
KOG0659	Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7
KOG2496	Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit
KOG3295	60S Ribosomal protein L13
KOG3320	40S ribosomal protein S7
KOG1774	Small nuclear ribonucleoprotein E
KOG3482	Small nuclear ribonucleoprotein (snRNP) SMF
KOG3172	Small nuclear ribonucleoprotein Sm D3
KOG0668	Casein kinase II, alpha subunit
KOG3092	Casein kinase II, beta subunit
KOG0653	Cyclin B and related kinase-activating proteins
KOG3484	Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins
KOG0594	Protein kinase PCTAIRE and related kinases
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG1973	Chromatin remodeling protein, contains PHD Zn-finger
KOG0676	Actin and related proteins
KOG3449	60S acidic ribosomal protein P2
KOG0679	Actin-related protein - Arp4p/Act3p
KOG1922	Rho GTPase effector BNI1 and related formins
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG3780	Thioredoxin binding protein TBP-2/VDUP1
KOG0800	FOG: Predicted E3 ubiquitin ligase
KOG0578	p21-activated serine/threonine protein kinase
KOG0662	Cyclin-dependent kinase CDK5
KOG0841	Multifunctional chaperone (14-3-3 family)
KOG0583	Serine/threonine protein kinase
KOG0580	Serine/threonine protein kinase
KOG1721	FOG: Zn-finger
KOG2330	Splicing factor 3b, subunit 2
KOG1074	Transcriptional repressor SALM
KOG1704	FOG: LIM domain
KOG0660	Mitogen-activated protein kinase
KOG0749	Mitochondrial ADP/ATP carrier proteins
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0601	Cyclin-dependent kinase WEE1
KOG2084	Predicted histone tail methylase containing SET domain
KOG3168	U1 snRNP component
KOG2165	Anaphase-promoting complex (APC), subunit 2
KOG2440	Pyrophosphate-dependent phosphofructo-1-kinase
KOG2441	mRNA splicing factor/probable chromatin binding snw family nuclear protein
KOG4204	Histone deacetylase complex, SIN3 component
KOG3259	Peptidyl-prolyl cis-trans isomerase
KOG0627	Heat shock transcription factor
KOG0643	Translation initiation factor 3, subunit i (eIF-3i)/TGF-beta receptor-interacting protein (TRIP-1)
KOG1113	cAMP-dependent protein kinase types I and II, regulatory subunit
KOG1453	Chimaerin and related Rho GTPase activating proteins
KOG0712	Molecular chaperone (DnaJ superfamily)
KOG1450	Predicted Rho GTPase-activating protein
KOG1463	26S proteasome regulatory complex, subunit RPN6/PSMD11
KOG0929	Guanine nucleotide exchange factor
KOG1076	Translation initiation factor 3, subunit c (eIF-3c)
KOG1597	Transcription initiation factor TFIIB
KOG1124	FOG: TPR repeat
KOG1561	CCAAT-binding factor, subunit B (HAP2)

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2169 - KOG2294	PIAS1 - FoxO1 PIAS1 - FoxO3 PIAS1 - FoxO4	CG7958 - CG11799 DIP:18140N - CG11799	NFI1 - Fhl1
KOG2462 - KOG4203	snail - Beta-catenin	CG10274 - CG4798	Ydr437w - Fur1p
KOG2652 - KOG3463	GTF2A1 - GTF2A2 Transcription Initiation Factor Iia Alpha Chain - GTF2A2	DIP:17546N - TfIIA-S DIP:17546N - TfIIA-S-2 TfIIA-L - TfIIA-S TfIIA-L - TfIIA-S-2	Toa1 - Toa2 Yeast Transcription Factor Iia - Toa2
KOG1142 - KOG2652	TAF12 - GTF2A1	DIP:19086N - TfIIA-L DIP:19086N - DIP:17546N	TAF61 - Toa1
KOG1142 - KOG3334	TAF12 - TAF9	Taf12 - DIP:239N	TAF61 - TAF17
KOG2549 - KOG3334	DIP:493N - TAF9 DIP:773N - TAF9 DIP:773N - DIP:239N TAF6 - TAF9	DIP:772N - DIP:239N DIP:778N - DIP:239N Taf6 - e(y)1	Taf6 - TAF17
KOG1142 - KOG2549	TAF12 - DIP:493N	Taf12 - DIP:778N	TAF61 - Taf6
KOG3302 - KOG3334	TBP - TAF9	Tbp - DIP:239N	DIP:1078N - TAF17 TBP1 - TAF17
KOG2549 - KOG3302	DIP:493N - TBP	DIP:778N - Tbp	Taf6 - TBP1 Taf6 - DIP:1078N Taf6 - DIP:80N
KOG1142 - KOG3302	TAF12 - TBP	Taf12 - Tbp	TAF61 - TBP1 TAF61 - DIP:1078N
KOG1472 - KOG3302	hGCN5L2 - TBP TAFII250 - TBP PCAF - TBP	DIP:147N - Tbp	DIP:147N - TBP1 DIP:147N - DIP:80N Spt7 - TBP1 Gcn5 - TBP1
KOG1342 - KOG1472	HDAC1 - TAFII250 HDAC1 - PCAF	dHDAC1 - Pcaf	Rpd3 - Gcn5
KOG0837 - KOG1472	c-Jun - TAFII250 c-Jun - PCAF	Jra - Pcaf	Gcn4 - Gcn5 Gcn4 - Spt7
KOG0837 - KOG0837	JunD - c-Jun JunD - JUNB C-Jun Homodimer - C-Jun Homodimer JUNB - c-Jun JUNB - JunD c-Jun - c-Jun c-Jun - JUNB c-Jun - JunD	Jra - Jra	Gcn4 - Gcn4
KOG0659 - KOG2496	CAK - DIP:5996N	CG6800 - CycH	KIN28 - CCL1
KOG3295 - KOG3320	RPL13 - RPS7	RpL13 - CG1883	RPL13B - Rps7a
KOG1774 - KOG3482	SmE - SNRPF	CG18591 - DebB	Sme1 - SMX3
KOG1774 - KOG3172	SmE - SmD3	CG18591 - DIP:21162N CG18591 - SmD3	Sme1 - SMD3
KOG3172 - KOG3482	SmD3 - SNRPF	SmD3 - DebB DIP:21162N - DebB	SMD3 - SMX3
KOG0668 - KOG3092	CK2alpha - Casein Kinase Ii CK2-alpha' subunit - Casein Kinase Ii	CKII-alpha - CKII-beta	CKA1 - CKB2 CKA1 - CKB1 CKA2 - CKB2 CKA2 - CKB1
KOG0653 - KOG3484	Cyclin B1 - CKS1B cyclin B2 - CKS1B	DIP:17624N - CG9790 CycG - DIP:102N CycG - CG9790	Clb3 - CKS1 Clb3 - DIP:102N Clb1 - CKS1 Clb1 - DIP:102N Clb6 - DIP:102N Clb6 - CKS1 Clb4 - CKS1 Clb4 - DIP:102N Cln1 - CKS1 Cln1 - DIP:102N Cln2 - CKS1 Cln2 - DIP:102N Clb2 - CKS1 Clb2 - DIP:102N Clb5 - CKS1 Clb5 - DIP:102N Cln3 - CKS1 Cln3 - DIP:102N
KOG0594 - KOG0653	CDC2 - cyclin B2 CDC2 - Cyclin B1 CDK4 - Cyclin B1 CDK2 - DIP:24234N CDK2 - Cyclin B1	Cdk4 - DIP:17624N CG30171 - CycG cdc2 - CycG	Cdc28 - Cln3 Cdc28 - Clb2 Cdc28 - Clb3 Cdc28 - Cln1 Cdc28 - Cln2 Cdc28 - Clb6 Cdc28 - Clb5 Cdc28 - Clb4 Cdc28 - Clb1 Cak1 - Cln3 Cak1 - Clb2 Cak1 - Clb3 Cak1 - Cln1 Cak1 - Cln2 Cak1 - Clb6 Cak1 - Clb5 Cak1 - Clb4 Cak1 - Clb1
KOG0594 - KOG3484	DIP:648N - CKS1B DIP:649N - CKS1B DIP:686N - CKS1B Cdc28p - CKS1B CDC2 - CKS1B CDK4 - CKS1B CDK6 - CKS1B CDK2 - CKS1B	cdc2 - DIP:102N cdc2 - CG9790	Cdc28 - DIP:102N Cdc28 - CKS1 Cak1 - DIP:102N Cak1 - CKS1
KOG1703 - KOG3295	PXN - RPL13 paxillin - RPL13 ARA55 - RPL13	CG32018 - RpL13	LRG - RPL13B
KOG0668 - KOG1973	CK2-alpha' subunit - ING1L	CG30171 - Bip2	CKA1 - Pho23 CKA2 - Pho23
KOG0676 - KOG3449	ACTG1 - RPLP2	Act42A - RpP1	actin - Rpp2b
KOG0676 - KOG0679	Actin - Act1p	Act87E - CG6546	actin - Arp4 actin - Actin
KOG0676 - KOG1922	Actin - Bni1p	Act42A - Capu	actin - Bnr1
KOG0940 - KOG3780	SMURF2 - TXNIP	CG7552 - CG7047 CG3099 - CG14696	Rsp5 - Ygr068c Rsp5 - DIP:4111N Rsp5 - Rod1
KOG0800 - KOG0940	RNF11 - AIP4 RNF11 - AIP2 RNF11 - SMURF1 RNF11 - NEDD4L RNF11 - SMURF2 RNF11 - AIP5 RNF11 - NEDD4 RNF11 - SMURF1	EG:22E5.12 - CG3099	DIP:6628N - Rsp5
KOG0578 - KOG0940	PAK - SMURF1 PAK - SMURF2 PAK - SMURF1 PAK - FLJ32109 PAK - KIAA1301 PAK - NEDD4	CG30171 - Nedd4	Ste20 - Rsp5 Cla4 - Rsp5
KOG0662 - KOG0841	DIP:320N - 14-3-3-beta DIP:320N - 14-3-3-zeta DIP:320N - 14-3-3tau	CG30171 - 14-3-3-epsilon	Pho85 - BMH1
KOG0841 - KOG0841	14-3-3-beta - 14-3-3tau 14-3-3-beta - 14.3.3-gamma 14-3-3-beta - 14-3-3-zeta 14-3-3-beta - 14-3-3-epsilon 14.3.3-gamma - 14-3-3tau 14.3.3-gamma - 14-3-3-zeta 14.3.3-gamma - 14-3-3-beta 14.3.3-gamma - 14-3-3-epsilon 14-3-3-zeta - 14-3-3-zeta 14-3-3-zeta - 14-3-3-epsilon 14-3-3-zeta - 14-3-3-beta 14-3-3-zeta - 14-3-3tau 14-3-3-zeta - 14.3.3-gamma 14-3-3-epsilon - 14-3-3-beta 14-3-3-epsilon - 14-3-3-zeta 14-3-3-epsilon - 14.3.3-gamma 14-3-3-epsilon - 14-3-3tau 14-3-3tau - 14-3-3-zeta 14-3-3tau - 14.3.3-gamma 14-3-3tau - 14-3-3-beta 14-3-3tau - 14-3-3-epsilon	14-3-3-epsilon - 14-3-3-epsilon	Bmh2 - BMH1 Bmh2 - Bmh2 BMH1 - Bmh2
KOG0578 - KOG0841	PAK4 - 14-3-3-zeta	CG30171 - 14-3-3-epsilon	Ste20 - BMH1 Ste20 - Bmh2 Cla4 - BMH1 Cla4 - Bmh2
KOG0676 - KOG0841	ACTG1 - 14-3-3-zeta	Act42A - 14-3-3-epsilon	actin - BMH1 actin - Bmh2 ARP1 - BMH1
KOG0583 - KOG1703	STK22C - ARA55	PNG - DIP:17944N CG30171 - stck	Kin2 - Ykr090w Ptk2p - Ykr090w
KOG0580 - KOG0583	HsAIRK-2 - STK22D	DIP:20399N - Par-1	Ipl1 - Kin2 Ipl1 - Ptk2p Ipl1 - Snf1
KOG1721 - KOG2330	PLZF - SF3b2 ZNF83 - SF3b2 PRDM4 - SF3b2 FLJ12586 - SF3b2 SIP1 - SF3b2 HIVEP1 - SF3b2 PLAGL1 - SF3b2 PLAG1 - SF3b2	odd - CG3605 bowl - CG3605 CG8159 - CG3605 D19A - CG3605 CG2116 - CG3605 CG10462 - CG3605 CG2889 - CG3605	Swi5 - Cus1 MIG1 - Cus1 Nrg1p - Cus1
KOG1721 - KOG2294	PLZF - FoxO3 PLZF - FoxH1 PLZF - FoxO1 PLZF - FoxO4 ZNF83 - FoxO3 ZNF83 - FoxH1 ZNF83 - FoxO1 ZNF83 - FoxO4 PRDM4 - FoxO3 PRDM4 - FoxH1 PRDM4 - FoxO1 PRDM4 - FoxO4 FLJ12586 - FoxO3 FLJ12586 - FoxH1 FLJ12586 - FoxO1 FLJ12586 - FoxO4 SIP1 - FoxO3 SIP1 - FoxH1 SIP1 - FoxO1 SIP1 - FoxO4 HIVEP1 - FoxO3 HIVEP1 - FoxH1 HIVEP1 - FoxO1 HIVEP1 - FoxO4 PLAGL1 - FoxO3 PLAGL1 - FoxH1 PLAGL1 - FoxO1 PLAGL1 - FoxO4 PLAG1 - FoxO3 PLAG1 - FoxH1 PLAG1 - FoxO1 PLAG1 - FoxO4	opa - CG11799 opa - fd59A CG7752 - CG11799 Aef1 - foxo CG10654 - CG11799 D19B - jumu CG14451 - fd59A DIP:17332N - CG11799 DIP:17378N - fd59A GI:24653568 - CG11799 DIP:17897N - CG11799 CG6808 - fd59A CG15710 - fd64A CG10959 - CG11799 CG2129 - fd59A CG7987 - fd59A CG17801 - CG11799 CG11696 - fd64A CkIIalpha-i1 - fd64A l(2)35Ea - CG11799 CG2678 - fd59A CG9797 - fd59A CG9797 - CG11799 CG8301 - CG11799 CG8301 - fd59A Sry-beta - CG11799 CG1647 - fd64A CG4730 - CG11799 CG7928 - CG11799 CG7928 - fd59A CG7386 - fd59A CG10147 - jumu CG8145 - fd59A	Swi5 - Fkh1 Swi5 - Fkh2p Swi5 - Hcm1p ADR1 - Fkh2p ADR1 - Hcm1 Yer028c - Hcm1 Fzf1 - Fkh1 MIG1 - Hcm1 Ygr067c - Hcm1 Ygr067c - Fkh2p RIM101 - Fkh1 Zap1 - Fkh1 Ace2 - Fkh1 Ace2 - Fkh2p Ace2 - Hcm1p
KOG1721 - KOG1973	IMAGE 3948563 - ING1L YY1 - p28ING5 YY1 - ING4 ZNF76 - ING1L SIP1 - ING1L Egr1 - p28ING5 Egr1 - ING4 KIAA0972 - ING1L	CG40145 - Bip2 opa - CG7379 CG10274 - CG7379 CG10267 - Bip2 CG17612 - Bip2 CG10543 - Bip2 MTF-1 - DIP:19186N MTF-1 - CG9293 CG4820 - CG6632 D19A - Bip2 D19A - CG7379 CG18476 - Bip2 su(Hw) - Bip2 DIP:19181N - DIP:19186N DIP:19181N - CG9293 CG10309 - Bip2 ken - Bip2 CG17568 - CG7379 CG10462 - Bip2 CG10462 - CG7379 EG:BACR42I17.11 - Bip2 CG2889 - Bip2 CG31365 - Bip2 CG4854 - Bip2 CG4936 - Bip2 Sry-delta - Bip2 CG7386 - Bip2 CG7386 - CG7379 CG10147 - Bip2 CG17806 - Bip2 CG11762 - Bip2 CG11798 - Bip2	DIP:150N - Pho23 Swi5 - YNG2 ADR1 - Yng1 Ace2 - Yng1
KOG1074 - KOG1721	FLJ20765 - E4F1 FLJ20765 - ZF6 FLJ20765 - SIP1 FLJ20765 - ZNF83 IMAGE 3948563 - SIP1 IMAGE 3948563 - KIAA0972 IMAGE 3948563 - ZNF76 KIAA0972 - IMAGE 3948563 KIAA0972 - SIP1 KIAA0972 - ZNF76 ZF6 - E4F1 ZF6 - SIP1 ZF6 - ZNF83 ZF6 - FLJ20765	CG10274 - CG7386 CG10274 - CG8159 CG10274 - CG17568 CG10274 - CG4360 CG10274 - CG4854 CG10274 - CG8388 CG10274 - CG8301 CG10274 - CG3032 CG10274 - CG18764 CG10274 - D19A CG10274 - drm CG10274 - CG10267 CG10274 - Aef1 CG10274 - CG17612 CG10274 - CG1233 CG10274 - DIP:121N CG10274 - DIP:17378N CG10274 - CG7928 CG10274 - CG3281 CG10274 - CG9797 CG10274 - l(2)35Ea CG10274 - CG11696 CG10274 - CG10959 CG10274 - CG17802 CG10274 - CG7204 CG10274 - Sry-beta CG10274 - sug CG10274 - CG7987 CG6254 - DIP:22012N CG6254 - CG17801 CG6254 - CG9797 CG6254 - DIP:17378N CG6254 - CG17802 CG3941 - l(2)35Ea CG3941 - CG9609 CG3941 - CG11696 CG3941 - rgr CG3941 - CG10147 CG3941 - CG8301 CG3941 - CG7386 CG3941 - DIP:17897N CG3941 - CG10309 CG3941 - CG18476 CG3941 - Phol CG3941 - CG10543 CG3941 - D19B CG3941 - CG10654 CG2052 - zfh1 CG2052 - DIP:18586N CG2052 - odd CG2052 - CG8388 CG2052 - wdn CG2052 - CG8301 CG2052 - CG10267 CG6808 - DIP:17378N CG6808 - CG9797 CG6808 - CG7928 CG6808 - CG2116 CG6808 - CG10267 CG6808 - opa CG6808 - Sry-beta CG31782 - CG9797 CG31782 - CG1792 CG31782 - CG7357 CG31782 - CG7386 CG31782 - CG8301 CG31782 - DIP:17897N CG31782 - D19A CG31782 - CG10654 crol - CG1832 crol - CG18262 crol - CG10543 crol - CG11971 crol - D19B crol - CG8301 crol - CG12391 crol - CG2202 crol - DIP:21597N crol - CG4820 crol - CG8319 crol - CG7386 crol - CG10654 DIP:20799N - CG8159 DIP:21597N - CG8301 DIP:21597N - CG12391 DIP:21597N - CG2202 DIP:21597N - crol DIP:21597N - CG8319 DIP:21597N - CG7386 DIP:21597N - CG7987 DIP:21597N - DIP:17897N DIP:21597N - CG4820 DIP:21597N - DIP:121N	Ydr437w - Msn4p
KOG1342 - KOG1721	Rpd3p - YY1 Rpd3p - DIP:36N HDAC2 - YY1 HDAC2 - PLZF HDAC2 - Sp1 HDAC2 - DIP:36N HDAC1 - PLZF HDAC1 - DIP:5990N HDAC1 - Miz-1 HDAC1 - AEBP2 HDAC1 - Sp1 HDAC3 - BCL6 HDAC3 - zid HDAC3 - PLZF	dHDAC1 - pho dHDAC1 - Phol	Hos2 - MIG1 Hos2 - Nrg1p Rpd3 - DIP:150N Rpd3 - Fzf1 Rpd3 - MIG1 Rpd3 - Nrg1p
KOG1704 - KOG1721	TES - ZNF510 PINCH-2 - ZFD25 FHL2 - ZNF36	Lmpt - sug Lmpt - CG7368 Lmpt - CG3032 Lmpt - CG17801 Lmpt - CG8145 stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) CG6522 - D19A CG6522 - CG11696 CG6522 - CG11695 CG6522 - su(Hw)	RGA1 - Swi5 RGA1 - Ace2 Rga1 - ADR1 Rga1 - Swi5 Rga1 - Ace2
KOG0660 - KOG1721	Erk1 - ZNF7 Erk1 - Sp1 Erk1 - YY1 p38-2 - YY1	p38b - Sry-beta p38b - CG8159 p38b - CG3281 p38b - CG17568 p38b - CG18764 p38b - CG10274 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	Kss1 - Ygr067c Slt2 - Ygr067c Slt2 - MIG1 Slt2 - Yer028c Slt2 - ADR1 Hog1 - DIP:150N Hog1 - MIG1 Smk1 - Ygr067c Smk1 - MIG1 Smk1 - Yer028c Smk1 - ADR1
KOG1703 - KOG1721	paxillin - ZNF510 paxillin - CTCF ARA55 - PLAG1 ARA55 - HIVEP1 ARA55 - SIP1 ARA55 - ZNF83 ARA55 - FLJ12586 ARA55 - PLAGL1 ARA55 - PRDM4 ARA55 - PLZF ARA55 - ZFD25 PINCH-2 - ZFD25 DIP:5931N - DIP:5990N	stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 unc-115 - bowl DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 CG30084 - CG3281 CG30084 - CG7357 CG30084 - DIP:17378N CG30084 - CG18011 CG30084 - CG17801 CG30084 - CG10959 CG30084 - CG8159 DIP:17944N - CG3281 DIP:17944N - CG7357 DIP:17944N - DIP:17378N DIP:17944N - CG18011 DIP:17944N - CG17801 DIP:17944N - CG10959 DIP:17944N - CG8159 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) DIP:21964N - bowl	Ykr090w - Swi5 Ykr090w - Ace2
KOG0668 - KOG1721	CK2-alpha' subunit - OSR1	CKII-alpha - CG4820 CKII-alpha - opa CKII-alpha - CG10979 CKII-alpha - CG10654 CKII-alpha - CG8159 CKII-alpha - DIP:17897N CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	CKA1 - Fzf1 CKA1 - MIG1 CKA1 - DIP:150N CKA1 - Ygr067c CKA1 - RIM101 CKA2 - Crz1p CKA2 - Fzf1 CKA2 - RIM101
KOG0676 - KOG1721	ACTG1 - ZNF510 ACTG1 - HIVEP1 ACTG1 - zid ACTC - HIVEP1 ACTC - ZNF510	Arp87C - CG40145 Act87E - CG2678 Act87E - CG1647 Act87E - CG7386 Act87E - CG17801 Act87E - jing Act87E - CG7752 Act87E - CG7357 Act42A - CG33213 Act42A - sug Act42A - l(2)35Ea Act42A - opa Act42A - CG1792 Act42A - DIP:19658N Act42A - hkb Act42A - odd Act42A - CG8159 Act42A - CG17568 Act42A - CG18764 Arp11 - CG9797	actin - RIM101 actin - Swi5 ARP1 - Fzf1 ARP1 - Nrg2 Arp9p - Swi5
KOG0940 - KOG1721	NEDD4 - IMAGE 3948563 NEDD4 - SIP1 NEDD4 - KIAA0972 NEDD4 - ZNF76 KIAA1301 - IMAGE 3948563 KIAA1301 - SIP1 KIAA1301 - KIAA0972 KIAA1301 - ZNF76 FLJ32109 - SIP1 SMURF2 - ZFD25 SMURF2 - ZNF-U69274 SMURF2 - PLAG1 SMURF2 - HIVEP1 SMURF2 - SIP1 SMURF2 - ZNF83 SMURF2 - FLJ12586 SMURF2 - PLAGL1 SMURF2 - PRDM4 SMURF2 - PLZF SMURF2 - IMAGE 3948563 SMURF2 - KIAA0972 SMURF2 - ZNF76 SMURF1 - ZFD25 SMURF1 - ZNF-U69274 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76	CG7552 - DIP:17332N CG7552 - GI:24653568 CG7552 - CG8301 CG7552 - odd CG7552 - CG10267 CG3003 - CG7928 CG3003 - CG9793 CG3099 - DIP:17378N CG3099 - CG6808 CG3099 - CG8319 CG3099 - CG17568 CG3099 - CG2116 CG3099 - CG18476 CG3099 - DIP:19928N CG3099 - CG33213 CG3099 - CG7357 CG3099 - CG9797 CG3099 - CG8301 Nedd4 - CG9817 Nedd4 - CG1832 Nedd4 - CG18262 Nedd4 - crol Nedd4 - CG10543 Nedd4 - CG11971 Nedd4 - D19B Su(dx) - DIP:17332N Su(dx) - CG4820 Su(dx) - GI:24653568	Rsp5 - Nrg2 Rsp5 - RIM101
KOG0749 - KOG1721	SLC25A5 - HIVEP1	DIP:19903N - pho Ant2 - CG18476 Ant2 - opa Ant2 - CG8301 Ant2 - DIP:17332N Ant2 - GI:24653568 Ant2 - CG7752 Ant2 - CG5245 Ant2 - CG8319 Ant2 - CG11247 Ant2 - CG10979	Pet9p - ADR1 AAC1 - Yer028c
KOG0841 - KOG1721	14-3-3-epsilon - BCL6 14-3-3-epsilon - PLZF 14-3-3tau - E4F1 14-3-3tau - ZF6 14-3-3tau - SIP1 14-3-3tau - ZNF83 14-3-3tau - FLJ20765	14-3-3-epsilon - CG10979 14-3-3-epsilon - CG9797 14-3-3-epsilon - CG6808 14-3-3-epsilon - CG2889 14-3-3-epsilon - CG10267 14-3-3-epsilon - DIP:22690N 14-3-3-epsilon - EP2237 14-3-3-epsilon - Aef1 14-3-3-epsilon - Sqz	Bmh2 - ADR1 BMH1 - ADR1 BMH1 - Fzf1
KOG0581 - KOG1721	MEK2 - ZNF7 MEK1 - ZNF7	CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	Pbs2 - ADR1 Mkk2 - ADR1 Mkk2 - Nrg2
KOG0601 - KOG1721	Wee1A - PLAG1 Wee1A - HIVEP1 Wee1A - SIP1 Wee1A - ZNF83 Wee1A - FLJ12586 Wee1A - PLAGL1 Wee1A - PRDM4 Wee1A - PLZF	wee - CG8301 wee - CkIIalpha-i1 wee - D19A wee - DIP:18586N wee - CG2052 wee - sug wee - CG11695	Swe1 - Ace2 Swe1 - Met31 Swe1 - ADR1 Swe1 - Swi5
KOG1721 - KOG3172	ZNF510 - SmD3	CG14655 - DIP:21162N CG2116 - SmD3	MIG1 - SMD3 Crz1p - SMD3
KOG1721 - KOG2084	ZNF510 - SMYD3	opa - CG9640 CG10274 - CG9640 Aef1 - CG17086 CG7204 - CG9640 CG10267 - CG9640 CG10979 - CG17085 CG10654 - CG17086 CG10654 - CG17085 CG10654 - CG9640 D19B - CG9640 CG3941 - CG9640 CG8159 - Bzd CG8159 - CG9640 CG17802 - CG9640 DIP:17378N - CG9640 CG10543 - CG9640 CG10543 - BG:DS07295.2 Phol - CG9640 D19A - CG9640 D19A - BG:DS07295.2 DIP:17897N - CG17085 DIP:17897N - CG9640 DIP:17897N - CG17086 CG6808 - CG9640 CG18764 - CG9640 CG18476 - CG9640 CG18476 - BG:DS07295.2 CG10959 - CG9640 su(Hw) - BG:DS07295.2 CG7987 - BcDNA:LD29892 CG10309 - CG9640 CG10309 - BG:DS07295.2 CG2116 - CG9640 CG11696 - CG9640 CG17568 - CG17085 CG17568 - CG17086 CG17568 - CG9640 EG:BACR42I17.11 - BG:DS07295.2 CG9609 - CG9640 l(2)35Ea - CG9640 l(2)35Ea - CG17085 CG9797 - CG9640 CG9797 - CG17085 rgr - CG9640 CG8301 - CG17085 CG8301 - CG9640 CG8301 - CG17086 CG4936 - BG:DS07295.2 Sry-delta - BG:DS07295.2 CG3281 - CG9640 CG7928 - CG9640 CG7928 - CG17085 CG7386 - CG9640 CG7386 - CG17086 CG10147 - CG9640 CG10147 - BG:DS07295.2 CG1792 - CG9640 CG11798 - BG:DS07295.2	Crz1p - Yhr207c
KOG1721 - KOG3168	HIVEP1 - SmB	CG10979 - SmB CG10654 - SmB CG11247 - SmB CG8159 - SmB CG4820 - SmB DIP:17897N - SmB CG6808 - SmB CG14711 - SmB CG2116 - SmB CG17568 - SmB CG10462 - SmB CG1603 - SmB CG8301 - SmB CG7386 - SmB	Nrg2 - Smb1 MIG1 - Smb1
KOG1721 - KOG2496	DIP:5990N - DIP:5996N	CG4496 - CycH CG18476 - CycH sug - CycH CTCF - CycH	Swi5 - CCL1 Zms1p - CCL1
KOG1721 - KOG2165	SIP1 - APC2	CG6254 - GI:20130331 CG17802 - GI:20130331 DIP:17378N - GI:20130331 D19A - GI:20130331 CG17801 - GI:20130331 CG9797 - GI:20130331 DIP:22012N - GI:20130331	Swi5 - APC2 ADR1 - APC2
KOG1721 - KOG2440	COASTER - PFKL RLF - PFKL ZNF510 - PFKL	l(2)35Ea - DIP:17602N CG8319 - DIP:17602N	ADR1 - Pfk2 ADR1 - Pfk1
KOG1721 - KOG2441	PLZF - SKIP ZNF83 - SKIP PRDM4 - SKIP FLJ12586 - SKIP SIP1 - SKIP HIVEP1 - SKIP PLAGL1 - SKIP PLAG1 - SKIP	CG10979 - Bx42 CG4820 - Bx42 CG17801 - Bx42 l(2)35Ea - Bx42 CG1647 - Bx42 CG7386 - Bx42	ADR1 - Prp45p Fzf1 - Prp45 Fzf1 - Prp45p
KOG1721 - KOG4203	Miz-1 - Beta-catenin ZNF36 - Beta-catenin ZNF36 - JUP DIP:5990N - Beta-catenin	opa - CG4798 CG10274 - CG4798 Aef1 - CG4798 DIP:17378N - CG4798 CG7987 - CG4798 CG2116 - CG4798 CG17568 - CG4798 CG2678 - CG4798 sug - CG4798 CG8301 - CG4798 CG7357 - CG4798 CG8319 - CG4798	Ydr437w - Fur1p Msn4p - Fur1p
KOG1721 - KOG4204	YY1 - mSin3A PLZF - mSin3A PLZF - DIP:278N zid - DIP:278N BCL6 - DIP:278N Sp1 - mSin3A	opa - Sin3A CG33213 - Sin3A CG8159 - Sin3A su(Hw) - Sin3A DIP:20799N - Sin3A zfh1 - Sin3A	DIP:150N - Sin3 Swi5 - Sin3 ADR1 - Sin3 Fzf1 - Sin3 RIM101 - Sin3
KOG1721 - KOG3259	KLF6 - Pin1	CG14655 - dod opa - dod CG33213 - dod odd - dod D19A - dod CG18764 - dod DIP:19658N - dod CG9797 - dod hkb - dod	ADR1 - ESS1 Ace2 - ESS1
KOG1721 - KOG1721	ZNF-U69274 - ZFD25 DIP:36N - YY1 FLJ20765 - E4F1 FLJ20765 - ZF6 FLJ20765 - SIP1 FLJ20765 - ZNF83 FLJ23392 - zid FLJ23392 - ZFP106 IMAGE 3948563 - SIP1 IMAGE 3948563 - KIAA0972 IMAGE 3948563 - ZNF76 YY1 - DIP:36N YY1 - AEBP2 YY1 - Egr1 Miz-1 - DIP:5990N Miz-1 - Sp1 PLZF - Sp1 PLZF - BCL6 PLZF - PLAG1 PLZF - HIVEP1 PLZF - SIP1 PLZF - ZNF83 PLZF - FLJ12586 PLZF - PLAGL1 PLZF - PRDM4 PLZF - Egr1 PLZF - zid ZFP106 - zid ZFP106 - FLJ23392 ZNF76 - IMAGE 3948563 ZNF76 - SIP1 ZNF76 - KIAA0972 MGC4054 - SIP1 ZNF83 - E4F1 ZNF83 - ZF6 ZNF83 - SIP1 ZNF83 - FLJ20765 ZNF83 - PLAG1 ZNF83 - HIVEP1 ZNF83 - FLJ12586 ZNF83 - PLAGL1 ZNF83 - PRDM4 ZNF83 - PLZF zid - BCL6 zid - ZFP106 zid - FLJ23392 zid - PLZF CTCF - DIP:5990N PRDM4 - PLAG1 PRDM4 - HIVEP1 PRDM4 - SIP1 PRDM4 - ZNF83 PRDM4 - FLJ12586 PRDM4 - PLAGL1 PRDM4 - PLZF AEBP2 - YY1 FLJ12586 - PLAG1 FLJ12586 - HIVEP1 FLJ12586 - SIP1 FLJ12586 - ZNF83 FLJ12586 - PLAGL1 FLJ12586 - PRDM4 FLJ12586 - PLZF COASTER - RLF SIP1 - E4F1 SIP1 - ZF6 SIP1 - ZNF83 SIP1 - FLJ20765 SIP1 - PLAG1 SIP1 - HIVEP1 SIP1 - FLJ12586 SIP1 - PLAGL1 SIP1 - PRDM4 SIP1 - PLZF SIP1 - MGC4054 SIP1 - IMAGE 3948563 SIP1 - KIAA0972 SIP1 - ZNF76 Egr1 - Sp1 Egr1 - PLZF Egr1 - YY1 DIP:5990N - Miz-1 DIP:5990N - CTCF KIAA0972 - IMAGE 3948563 KIAA0972 - SIP1 KIAA0972 - ZNF76 ZF6 - E4F1 ZF6 - SIP1 ZF6 - ZNF83 ZF6 - FLJ20765 ZFD25 - ZNF-U69274 HIVEP1 - PLAG1 HIVEP1 - SIP1 HIVEP1 - ZNF83 HIVEP1 - FLJ12586 HIVEP1 - PLAGL1 HIVEP1 - PRDM4 HIVEP1 - PLZF E4F1 - ZF6 E4F1 - SIP1 E4F1 - ZNF83 E4F1 - FLJ20765 RLF - COASTER BCL6 - BCL6 BCL6 - zid BCL6 - PLZF PLAGL1 - PLAG1 PLAGL1 - HIVEP1 PLAGL1 - SIP1 PLAGL1 - ZNF83 PLAGL1 - FLJ12586 PLAGL1 - PRDM4 PLAGL1 - PLZF Sp1 - Egr1 Sp1 - PLZF Sp1 - Miz-1 PLAG1 - HIVEP1 PLAG1 - SIP1 PLAG1 - ZNF83 PLAG1 - FLJ12586 PLAG1 - PLAGL1 PLAG1 - PRDM4 PLAG1 - PLZF	CG40145 - CG11798 wdn - CG4854 wdn - CG4360 wdn - CG11247 wdn - CG10979 wdn - DIP:18586N wdn - CG2052 wdn - CG9797 EP2237 - CG17568 EP2237 - DIP:22690N EP2237 - CG7386 EP2237 - CG8159 DIP:121N - CG17612 DIP:121N - D19A DIP:121N - CG1233 DIP:121N - CG10274 DIP:121N - CG8319 DIP:121N - CG7386 DIP:121N - CG7987 DIP:121N - DIP:21597N DIP:121N - DIP:17897N DIP:121N - CG4820 CG14655 - CG17568 opa - CG8319 opa - CG8145 opa - CG1792 opa - CG8301 opa - DIP:17332N opa - GI:24653568 opa - CG7752 opa - CG7928 opa - DIP:17378N opa - CG9797 opa - CG2116 opa - CG6808 opa - CG10267 opa - CG18476 opa - hkb opa - D19A opa - odd opa - CG15073 opa - CG17802 opa - DIP:19658N CG10274 - CG7386 CG10274 - CG8159 CG10274 - CG17568 CG10274 - CG4360 CG10274 - CG4854 CG10274 - CG8388 CG10274 - CG8301 CG10274 - CG3032 CG10274 - CG18764 CG10274 - D19A CG10274 - drm CG10274 - CG10267 CG10274 - Aef1 CG10274 - CG17612 CG10274 - CG1233 CG10274 - DIP:121N CG10274 - DIP:17378N CG10274 - CG7928 CG10274 - CG3281 CG10274 - CG9797 CG10274 - l(2)35Ea CG10274 - CG11696 CG10274 - CG10959 CG10274 - CG17802 CG10274 - CG7204 CG10274 - Sry-beta CG10274 - sug CG10274 - CG7987 CG7752 - CG8301 CG7752 - DIP:17332N CG7752 - GI:24653568 CG7752 - opa CG7752 - su(Hw) CG7752 - CG2678 CG7752 - CG10462 CG7752 - jing CG33213 - CG14451 CG33213 - CG14962 CG33213 - CG7987 CG33213 - CG18764 CG33213 - CG10267 CG33213 - CG17568 CG33213 - CG2116 CG33213 - CG18476 CG33213 - DIP:19928N Aef1 - CG17568 Aef1 - CG4360 Aef1 - CG4854 Aef1 - CG8388 Aef1 - CG7386 Aef1 - CG8301 Aef1 - CG3032 Aef1 - CG18764 Aef1 - D19A Aef1 - drm Aef1 - CG10267 Aef1 - CG10274 Aef1 - CG7357 Aef1 - CG2678 CG7204 - CG7386 CG7204 - l(2)35Ea CG7204 - EG:95B7.7 CG7204 - DIP:17378N CG7204 - CG7928 CG7204 - CG3281 CG7204 - CG9797 CG7204 - CG17568 CG7204 - CG11696 CG7204 - CG10959 CG7204 - CG18764 CG7204 - D19A CG7204 - CG17802 CG7204 - CG10267 CG7204 - CG10274 CG7204 - CG8301 CG7204 - CG4936 CG10267 - CG10267 CG10267 - CG7386 CG10267 - CG17568 CG10267 - CG4360 CG10267 - CG4854 CG10267 - CG8388 CG10267 - CG8301 CG10267 - CG3032 CG10267 - CG18764 CG10267 - D19A CG10267 - drm CG10267 - Aef1 CG10267 - CG10274 CG10267 - CG1792 CG10267 - CG7963 CG10267 - CG2116 CG10267 - CG10321 CG10267 - CG17385 CG10267 - CG17802 CG10267 - CG7928 CG10267 - DIP:17378N CG10267 - CG9797 CG10267 - CG6808 CG10267 - opa CG10267 - CG2889 CG10267 - CG33213 CG10267 - CG3281 CG10267 - l(2)35Ea CG10267 - CG11696 CG10267 - CG10959 CG10267 - CG7204 CG10267 - odd CG10267 - CG2052 CG10267 - DIP:18586N CG10979 - CG10462 CG10979 - CG4730 CG10979 - CG32767 CG10979 - CG7101 CG10979 - CG9609 CG10979 - CG13620 CG10979 - CG8319 CG10979 - CG11247 CG10979 - wdn CG10979 - CG17801 CG10979 - l(2)35Ea CG10979 - CG10654 CG10979 - CG8159 CG10979 - CG4820 CG10979 - DIP:17897N CG10654 - CG4730 CG10654 - CG8301 CG10654 - CG9797 CG10654 - CG17801 CG10654 - CG10959 CG10654 - DIP:17897N CG10654 - CG4936 CG10654 - CG6689 CG10654 - CG7386 CG10654 - CG17568 CG10654 - CG7928 CG10654 - l(2)35Ea CG10654 - CG1792 CG10654 - CG7357 CG10654 - CG31782 CG10654 - D19A CG10654 - CG4820 CG10654 - CG9609 CG10654 - CG11696 CG10654 - rgr CG10654 - CG10147 CG10654 - CG10309 CG10654 - CG18476 CG10654 - Phol CG10654 - CG10543 CG10654 - CG3941 CG10654 - D19B CG10654 - CG12942 CG10654 - CG8159 CG10654 - CG11247 CG10654 - crol CG10654 - CG8319 CG10654 - CG10979 CG6254 - DIP:22012N CG6254 - CG17801 CG6254 - CG9797 CG6254 - DIP:17378N CG6254 - CG17802 CG11247 - CG17802 CG11247 - CG10979 CG11247 - wdn CG11247 - CG11696 CG11247 - CG7386 CG11247 - DIP:17897N CG11247 - CG4820 CG11247 - CG10654 CG11247 - CG8319 CG11247 - l(2)35Ea D19B - l(2)35Ea D19B - CG14441 D19B - CG1832 D19B - CG18262 D19B - crol D19B - CG10543 D19B - CG11971 D19B - CG9609 D19B - CG11696 D19B - rgr D19B - CG10147 D19B - CG8301 D19B - CG7386 D19B - DIP:17897N D19B - CG10309 D19B - CG18476 D19B - Phol D19B - CG10543 D19B - CG3941 D19B - CG10654 D19B - D19A D19B - CG18764 D19B - CG8159 drm - CG7101 drm - CG17568 drm - CG4360 drm - CG4854 drm - CG8388 drm - CG7386 drm - CG8301 drm - CG3032 drm - CG18764 drm - D19A drm - CG10267 drm - Aef1 drm - CG10274 odd - D19A odd - CG14711 odd - l(2)35Ea odd - CG7386 odd - CG9797 odd - bowl odd - CG11695 odd - CG8301 odd - CG10267 odd - zfh1 odd - DIP:18586N odd - CG2052 odd - CG1792 odd - DIP:19658N odd - hkb odd - opa odd - CG2889 odd - CG8159 bowl - CG7386 bowl - odd CG14451 - CG33213 jim - CG14711 CG17612 - CG7357 CG17612 - CG7386 CG17612 - CG8159 CG17612 - D19A CG17612 - CG1233 CG17612 - DIP:121N CG17612 - CG10274 CG3941 - l(2)35Ea CG3941 - CG9609 CG3941 - CG11696 CG3941 - rgr CG3941 - CG10147 CG3941 - CG8301 CG3941 - CG7386 CG3941 - DIP:17897N CG3941 - CG10309 CG3941 - CG18476 CG3941 - Phol CG3941 - CG10543 CG3941 - D19B CG3941 - CG10654 CG2052 - zfh1 CG2052 - DIP:18586N CG2052 - odd CG2052 - CG8388 CG2052 - wdn CG2052 - CG8301 CG2052 - CG10267 GI:24645129 - CG13620 CG8159 - CG3281 CG8159 - Sry-beta CG8159 - CG17568 CG8159 - CG18764 CG8159 - CG8159 CG8159 - CG10274 CG8159 - CG7386 CG8159 - CG7357 CG8159 - DIP:17378N CG8159 - CG18011 CG8159 - CG17801 CG8159 - CG10959 CG8159 - CG1647 CG8159 - DIP:20799N CG8159 - DIP:22690N CG8159 - EP2237 CG8159 - CG4730 CG8159 - CG8301 CG8159 - CG12942 CG8159 - DIP:17897N CG8159 - CG10654 CG8159 - CG1792 CG8159 - CG9793 CG8159 - CG17612 CG8159 - D19A CG8159 - D19B CG8159 - CG2889 CG8159 - odd CG8159 - CG10979 CG8159 - CG4820 CG8159 - DIP:23106N CG9793 - CG18764 CG9793 - CG7928 CG9793 - CG1792 CG9793 - CG7386 CG9793 - CG8159 CG9793 - DIP:23106N CG17802 - CG8319 CG17802 - CG7386 CG17802 - l(2)35Ea CG17802 - CG11247 CG17802 - CG7928 CG17802 - CG15073 CG17802 - opa CG17802 - CG18011 CG17802 - CG4820 CG17802 - DIP:17378N CG17802 - CG3281 CG17802 - CG9797 CG17802 - CG17568 CG17802 - CG11696 CG17802 - CG10959 CG17802 - CG18764 CG17802 - D19A CG17802 - CG10267 CG17802 - CG7204 CG17802 - CG10274 CG17802 - CG10321 CG17802 - CG17385 CG17802 - CG8301 CG17802 - CG17801 CG17802 - DIP:22012N CG17802 - CG6254 CG11971 - CG10147 CG11971 - CG1832 CG11971 - CG18262 CG11971 - crol CG11971 - CG10543 CG11971 - D19B CG9650 - DIP:22634N CG16779 - CG2678 CG16779 - CG10543 DIP:17332N - CG7928 DIP:17332N - GI:24653568 DIP:17332N - CG7386 DIP:17332N - CG8319 DIP:17332N - CG8301 DIP:17332N - EG:95B7.7 DIP:17332N - CG4820 DIP:17332N - CG7752 DIP:17332N - opa DIP:17332N - l(2)35Ea DIP:17378N - CG7386 DIP:17378N - CG10462 DIP:17378N - CG6808 DIP:17378N - CG7928 DIP:17378N - CG3281 DIP:17378N - CG9797 DIP:17378N - l(2)35Ea DIP:17378N - CG17568 DIP:17378N - CG11696 DIP:17378N - CG10959 DIP:17378N - CG18764 DIP:17378N - D19A DIP:17378N - CG17802 DIP:17378N - CG10267 DIP:17378N - CG7204 DIP:17378N - CG10274 DIP:17378N - CG2116 DIP:17378N - opa DIP:17378N - CG7357 DIP:17378N - CG18011 DIP:17378N - CG17801 DIP:17378N - CG8159 DIP:17378N - CG4936 DIP:17378N - CTCF DIP:17378N - DIP:22012N DIP:17378N - CG6254 DIP:17378N - CG8301 DIP:17378N - CG4820 DIP:17378N - CG7987 GI:24653568 - CG7928 GI:24653568 - CG7386 GI:24653568 - CG8319 GI:24653568 - DIP:17332N GI:24653568 - CG8301 GI:24653568 - EG:95B7.7 GI:24653568 - CG4820 GI:24653568 - l(2)35Ea GI:24653568 - CG7752 GI:24653568 - opa CG17385 - CG10321 CG17385 - CG17802 CG17385 - CG10267 CG17385 - D19A CG10543 - CG1832 CG10543 - CG18262 CG10543 - crol CG10543 - CG11971 CG10543 - D19B CG10543 - CTCF CG10543 - CG11798 CG10543 - l(2)35Ea CG10543 - CG9609 CG10543 - CG11696 CG10543 - rgr CG10543 - CG10147 CG10543 - CG8301 CG10543 - CG7386 CG10543 - DIP:17897N CG10543 - CG10309 CG10543 - CG18476 CG10543 - Phol CG10543 - CG3941 CG10543 - D19B CG10543 - CG10654 CG10543 - CG2678 CG10543 - CG16779 CG10543 - EG:BACR42I17.11 CG10543 - Sry-delta CG10543 - CG4936 CG10543 - su(Hw) CG10543 - D19A MTF-1 - DIP:19181N CG4496 - CG2116 CG4496 - CTCF CG4496 - sug CG4496 - CG18476 Phol - l(2)35Ea Phol - CG9609 Phol - CG11696 Phol - rgr Phol - CG10147 Phol - CG8301 Phol - CG7386 Phol - DIP:17897N Phol - CG10309 Phol - CG18476 Phol - CG10543 Phol - CG3941 Phol - D19B Phol - CG10654 Phol - pho CG4820 - CG7928 CG4820 - CG7386 CG4820 - CG18011 CG4820 - CG15073 CG4820 - CG17802 CG4820 - CG7987 CG4820 - DIP:17332N CG4820 - GI:24653568 CG4820 - DIP:19928N CG4820 - DIP:17897N CG4820 - CG10654 CG4820 - CG8319 CG4820 - CG8301 CG4820 - EG:95B7.7 CG4820 - CG11247 CG4820 - CG10366 CG4820 - DIP:21597N CG4820 - DIP:121N CG4820 - CG7357 CG4820 - CG4730 CG4820 - l(2)35Ea CG4820 - CG9797 CG4820 - CG2116 CG4820 - DIP:17378N CG4820 - crol CG4820 - CG2678 CG4820 - CG10979 CG4820 - CG8159 CG6689 - CG4730 CG6689 - DIP:17897N CG6689 - CG4936 CG6689 - CG17801 CG6689 - CG10654 D19A - l(2)35Ea D19A - CG7386 D19A - CG9797 D19A - odd D19A - CG17801 D19A - CG17568 D19A - CG4360 D19A - CG4854 D19A - CG8388 D19A - CG8301 D19A - CG3032 D19A - CG18764 D19A - drm D19A - CG10267 D19A - Aef1 D19A - CG10274 D19A - hkb D19A - opa D19A - CG10959 D19A - CG17802 D19A - CG7204 D19A - CkIIalpha-i1 D19A - CG2116 D19A - DIP:17378N D19A - CG7928 D19A - CG3281 D19A - CG11696 D19A - CG17385 D19A - CG15336 D19A - CG1792 D19A - CG7357 D19A - DIP:17897N D19A - CG31782 D19A - CG10654 D19A - EG:BACR42I17.11 D19A - Sry-delta D19A - CG10147 D19A - CG11798 D19A - CG4936 D19A - CG10309 D19A - su(Hw) D19A - CG18476 D19A - CG10543 D19A - CG9609 D19A - DIP:19658N D19A - EG:95B7.7 D19A - CG17612 D19A - CG1233 D19A - DIP:121N D19A - D19B D19A - CG8159 DIP:17897N - CG4730 DIP:17897N - CG8301 DIP:17897N - CG9797 DIP:17897N - CG17801 DIP:17897N - CG10959 DIP:17897N - CG10654 DIP:17897N - CG4936 DIP:17897N - CG6689 DIP:17897N - CG7928 DIP:17897N - l(2)35Ea DIP:17897N - CG7386 DIP:17897N - CG1792 DIP:17897N - CG7357 DIP:17897N - CG31782 DIP:17897N - D19A DIP:17897N - CG4820 DIP:17897N - CG9609 DIP:17897N - CG11696 DIP:17897N - rgr DIP:17897N - CG10147 DIP:17897N - CG10309 DIP:17897N - CG18476 DIP:17897N - Phol DIP:17897N - CG10543 DIP:17897N - CG3941 DIP:17897N - D19B DIP:17897N - CG12942 DIP:17897N - CG8159 DIP:17897N - CG11247 DIP:17897N - CG8319 DIP:17897N - CG7987 DIP:17897N - DIP:21597N DIP:17897N - DIP:121N DIP:17897N - CG17568 DIP:17897N - CG10979 CG6808 - DIP:17378N CG6808 - CG9797 CG6808 - CG7928 CG6808 - CG2116 CG6808 - CG10267 CG6808 - opa CG6808 - Sry-beta CG14711 - CG15710 CG14711 - odd CG14711 - l(2)35Ea CG14711 - jim CG14711 - CG7357 CG18764 - CG1792 CG18764 - CG7386 CG18764 - CG9793 CG18764 - CG8159 CG18764 - CG17568 CG18764 - CG4360 CG18764 - CG4854 CG18764 - CG8388 CG18764 - CG8301 CG18764 - CG3032 CG18764 - D19A CG18764 - drm CG18764 - CG10267 CG18764 - Aef1 CG18764 - CG10274 CG18764 - CG9797 CG18764 - CG4936 CG18764 - l(2)35Ea CG18764 - EG:95B7.7 CG18764 - CG33213 CG18764 - DIP:17378N CG18764 - CG7928 CG18764 - CG3281 CG18764 - CG11696 CG18764 - CG10959 CG18764 - CG17802 CG18764 - CG7204 CG18764 - CG10147 CG18764 - Sry-beta CG18764 - D19B CG18476 - CG9609 CG18476 - CTCF CG18476 - sug CG18476 - CG4496 CG18476 - l(2)35Ea CG18476 - CG11696 CG18476 - rgr CG18476 - CG10147 CG18476 - CG8301 CG18476 - CG7386 CG18476 - DIP:17897N CG18476 - CG10309 CG18476 - Phol CG18476 - CG10543 CG18476 - CG3941 CG18476 - D19B CG18476 - CG10654 CG18476 - EG:BACR42I17.11 CG18476 - Sry-delta CG18476 - CG11798 CG18476 - CG4936 CG18476 - su(Hw) CG18476 - D19A CG18476 - CG17568 CG18476 - CG2116 CG18476 - DIP:19928N CG18476 - CG33213 CG18476 - opa CG15710 - CG14711 CG15710 - CG1647 CG15710 - CkIIalpha-i1 CG15710 - CG11696 CG31782 - CG9797 CG31782 - CG1792 CG31782 - CG7357 CG31782 - CG7386 CG31782 - CG8301 CG31782 - DIP:17897N CG31782 - D19A CG31782 - CG10654 DIP:18586N - zfh1 DIP:18586N - CG2052 DIP:18586N - odd DIP:18586N - CG8388 DIP:18586N - wdn DIP:18586N - CG8301 DIP:18586N - CG10267 pho - Phol pho - CG3032 CG10959 - l(2)35Ea CG10959 - CG7386 CG10959 - DIP:17897N CG10959 - CG10654 CG10959 - CG8301 CG10959 - D19A CG10959 - CG17802 CG10959 - CG7204 CG10959 - CG3281 CG10959 - CG7357 CG10959 - DIP:17378N CG10959 - CG18011 CG10959 - CG17801 CG10959 - CG8159 CG10959 - CG7928 CG10959 - CG9797 CG10959 - CG17568 CG10959 - CG11696 CG10959 - CG18764 CG10959 - CG10267 CG10959 - CG10274 CG10959 - CG4730 CG10959 - CG2129 su(Hw) - CG11696 su(Hw) - CG11695 su(Hw) - EG:BACR42I17.11 su(Hw) - Sry-delta su(Hw) - CG10147 su(Hw) - CG11798 su(Hw) - CG4936 su(Hw) - CG10309 su(Hw) - CG18476 su(Hw) - D19A su(Hw) - CG10543 su(Hw) - CG7752 su(Hw) - CG18262 su(Hw) - CG9609 CG1233 - CG17612 CG1233 - D19A CG1233 - DIP:121N CG1233 - CG10274 CG2129 - CG2129 CG2129 - CG11696 CG2129 - CG10959 CG7987 - CG1832 CG7987 - CG7386 CG7987 - CG17568 CG7987 - CG4820 CG7987 - CG11798 CG7987 - CG2116 CG7987 - CG14962 CG7987 - CG33213 CG7987 - sug CG7987 - CG10274 CG7987 - CG8319 CG7987 - DIP:21597N CG7987 - DIP:17897N CG7987 - DIP:121N CG7987 - CG7928 CG7987 - DIP:17378N CG7987 - CG9797 CG7368 - sug DIP:18917N - ovo crol - CG1832 crol - CG18262 crol - CG10543 crol - CG11971 crol - D19B crol - CG8301 crol - CG12391 crol - CG2202 crol - DIP:21597N crol - CG4820 crol - CG8319 crol - CG7386 crol - CG10654 CG15073 - CG8319 CG15073 - CG7386 CG15073 - CG18011 CG15073 - CG4820 CG15073 - CG17802 CG15073 - CG7928 CG15073 - opa DIP:19181N - MTF-1 CG10309 - l(2)35Ea CG10309 - CG9609 CG10309 - CG11696 CG10309 - rgr CG10309 - CG10147 CG10309 - CG8301 CG10309 - CG7386 CG10309 - DIP:17897N CG10309 - CG18476 CG10309 - Phol CG10309 - CG10543 CG10309 - CG3941 CG10309 - D19B CG10309 - CG10654 CG10309 - EG:BACR42I17.11 CG10309 - Sry-delta CG10309 - CG11798 CG10309 - CG4936 CG10309 - su(Hw) CG10309 - D19A ovo - DIP:18917N CG32767 - CG4730 CG32767 - CG10979 DIP:19658N - CG1792 DIP:19658N - hkb DIP:19658N - odd DIP:19658N - CG7386 DIP:19658N - CG12701 DIP:19658N - D19A DIP:19658N - opa CG17801 - CG4730 CG17801 - DIP:17897N CG17801 - CG10654 CG17801 - CG4936 CG17801 - CG6689 CG17801 - CG3281 CG17801 - CG7357 CG17801 - DIP:17378N CG17801 - CG18011 CG17801 - CG10959 CG17801 - CG8159 CG17801 - CG8301 CG17801 - D19A CG17801 - CG1647 CG17801 - CG7386 CG17801 - CG9797 CG17801 - CG8145 CG17801 - DIP:22012N CG17801 - CG17802 CG17801 - CG6254 CG17801 - CG12942 CG17801 - CG10979 CG17801 - l(2)35Ea GI:17647565 - sug GI:17647565 - CG10348 DIP:19928N - CG4820 DIP:19928N - CG17568 DIP:19928N - CG2116 DIP:19928N - CG18476 DIP:19928N - CG33213 CG14441 - D19B CG3032 - CG17568 CG3032 - CG4360 CG3032 - CG4854 CG3032 - CG8388 CG3032 - CG7386 CG3032 - CG8301 CG3032 - CG18764 CG3032 - D19A CG3032 - drm CG3032 - CG10267 CG3032 - Aef1 CG3032 - CG10274 CG3032 - pho CG10348 - CG8145 CG10348 - sug CG10348 - GI:17647565 CG4360 - CG4854 CG4360 - wdn CG4360 - CG17568 CG4360 - CG8388 CG4360 - CG7386 CG4360 - CG8301 CG4360 - CG3032 CG4360 - CG18764 CG4360 - D19A CG4360 - drm CG4360 - CG10267 CG4360 - Aef1 CG4360 - CG10274 CG2116 - CG10462 CG2116 - CG3281 CG2116 - Sry-beta CG2116 - CG7928 CG2116 - DIP:17378N CG2116 - CG9797 CG2116 - CG6808 CG2116 - CG10267 CG2116 - opa CG2116 - D19A CG2116 - CG17568 CG2116 - CG18476 CG2116 - DIP:19928N CG2116 - CG33213 CG2116 - CG11798 CG2116 - CG7987 CG2116 - CG7357 CG2116 - CG4496 CG2116 - CG1792 CG2116 - CG7963 CG2116 - CG8301 CG2116 - CG4820 CG2120 - CkIIalpha-i1 CG2120 - CG7101 CG2120 - CG8301 CG15336 - D19A CG18262 - CG1832 CG18262 - crol CG18262 - CG10543 CG18262 - CG11971 CG18262 - D19B CG18262 - CG11696 CG18262 - su(Hw) CG11696 - CG7386 CG11696 - CG11902 CG11696 - CG1647 CG11696 - CkIIalpha-i1 CG11696 - CG15710 CG11696 - DIP:17378N CG11696 - CG7928 CG11696 - CG3281 CG11696 - CG9797 CG11696 - l(2)35Ea CG11696 - CG17568 CG11696 - CG10959 CG11696 - CG18764 CG11696 - D19A CG11696 - CG17802 CG11696 - CG10267 CG11696 - CG7204 CG11696 - CG10274 CG11696 - CG18262 CG11696 - su(Hw) CG11696 - CG9609 CG11696 - rgr CG11696 - CG10147 CG11696 - CG8301 CG11696 - DIP:17897N CG11696 - CG10309 CG11696 - CG18476 CG11696 - Phol CG11696 - CG10543 CG11696 - CG3941 CG11696 - D19B CG11696 - CG10654 CG11696 - CG11695 CG11696 - CG2129 CG11696 - CG11247 CG17568 - CG7386 CG17568 - DIP:22690N CG17568 - CG8159 CG17568 - EP2237 CG17568 - CG7987 CG17568 - CG14655 CG17568 - CG8301 CG17568 - CG10654 CG17568 - DIP:17378N CG17568 - CG7928 CG17568 - CG3281 CG17568 - CG9797 CG17568 - l(2)35Ea CG17568 - CG11696 CG17568 - CG10959 CG17568 - CG18764 CG17568 - D19A CG17568 - CG17802 CG17568 - CG10267 CG17568 - CG7204 CG17568 - CG10274 CG17568 - CTCF CG17568 - CG2116 CG17568 - CG18476 CG17568 - DIP:19928N CG17568 - CG33213 CG17568 - DIP:17897N CG17568 - sug CG17568 - CG4360 CG17568 - CG4854 CG17568 - CG8388 CG17568 - CG3032 CG17568 - drm CG17568 - Aef1 CG17568 - CG11798 CG17568 - Sry-beta CG10366 - CG4820 CG10462 - DIP:17378N CG10462 - CG2116 CG10462 - CG10979 CG10462 - CG7386 CG10462 - CG2678 CG10462 - CG7752 CG10631 - CG12391 CG12942 - CG4730 CG12942 - CG8301 CG12942 - CG17801 CG12942 - CG7386 CG12942 - DIP:17897N CG12942 - CG8159 CG12942 - CG10654 EG:BACR42I17.11 - Sry-delta EG:BACR42I17.11 - CG10147 EG:BACR42I17.11 - CG11798 EG:BACR42I17.11 - CG4936 EG:BACR42I17.11 - CG10309 EG:BACR42I17.11 - su(Hw) EG:BACR42I17.11 - CG18476 EG:BACR42I17.11 - D19A EG:BACR42I17.11 - CG10543 CG9609 - CG18476 CG9609 - CG10147 CG9609 - su(Hw) CG9609 - D19A CG9609 - CG2678 CG9609 - l(2)35Ea CG9609 - CG11696 CG9609 - rgr CG9609 - CG8301 CG9609 - CG7386 CG9609 - DIP:17897N CG9609 - CG10309 CG9609 - Phol CG9609 - CG10543 CG9609 - CG3941 CG9609 - D19B CG9609 - CG10654 CG9609 - CG7101 CG9609 - CG10979 EG:95B7.7 - CG4936 EG:95B7.7 - CG7928 EG:95B7.7 - CG7204 EG:95B7.7 - l(2)35Ea EG:95B7.7 - CG18764 EG:95B7.7 - CG4730 EG:95B7.7 - CG7386 EG:95B7.7 - CG8319 EG:95B7.7 - DIP:17332N EG:95B7.7 - CG8301 EG:95B7.7 - CG4820 EG:95B7.7 - GI:24653568 EG:95B7.7 - D19A DIP:20799N - CG8159 CG2889 - CG10267 CG2889 - odd CG2889 - CG8159 CkIIalpha-i1 - CG2120 CkIIalpha-i1 - CG1647 CkIIalpha-i1 - CG11696 CkIIalpha-i1 - CG15710 CkIIalpha-i1 - CG8301 CkIIalpha-i1 - D19A CG2202 - CG8301 CG2202 - CG12391 CG2202 - crol CG2202 - DIP:21597N l(2)35Ea - l(2)35Ea l(2)35Ea - CG7386 l(2)35Ea - CG8301 l(2)35Ea - CG10959 l(2)35Ea - D19A l(2)35Ea - CG17802 l(2)35Ea - CG7204 l(2)35Ea - CG4936 l(2)35Ea - EG:95B7.7 l(2)35Ea - CG18764 l(2)35Ea - CG14711 l(2)35Ea - sug l(2)35Ea - DIP:17378N l(2)35Ea - CG7928 l(2)35Ea - CG3281 l(2)35Ea - CG9797 l(2)35Ea - CG17568 l(2)35Ea - CG11696 l(2)35Ea - CG10267 l(2)35Ea - CG10274 l(2)35Ea - DIP:17897N l(2)35Ea - CG10654 l(2)35Ea - DIP:17332N l(2)35Ea - GI:24653568 l(2)35Ea - CG9609 l(2)35Ea - rgr l(2)35Ea - CG10147 l(2)35Ea - CG10309 l(2)35Ea - CG18476 l(2)35Ea - Phol l(2)35Ea - CG10543 l(2)35Ea - CG3941 l(2)35Ea - D19B l(2)35Ea - CG8319 l(2)35Ea - odd l(2)35Ea - CG7357 l(2)35Ea - CG4730 l(2)35Ea - CG4820 l(2)35Ea - CG11247 l(2)35Ea - CG10979 l(2)35Ea - CG17801 CG31365 - CG7386 CG31365 - CG9797 CG10321 - CG17385 CG10321 - CG17802 CG10321 - CG10267 CG11695 - odd CG11695 - CG11696 CG11695 - su(Hw) CG11695 - sug CG11695 - CG7386 CG11695 - CG7928 CG11695 - CTCF jing - CG7752 CG2678 - CG2678 CG2678 - CG9797 CG2678 - CG16779 CG2678 - CG7386 CG2678 - CG9609 CG2678 - CG10543 CG2678 - CG10462 CG2678 - CG7752 CG2678 - CG4820 CG2678 - CG7357 CG2678 - Aef1 CG18011 - CG7386 CG18011 - CG15073 CG18011 - CG4820 CG18011 - CG17802 CG18011 - CG3281 CG18011 - CG7357 CG18011 - DIP:17378N CG18011 - CG17801 CG18011 - CG10959 CG18011 - CG8159 CG12391 - CG10631 CG12391 - CG8301 CG12391 - CG2202 CG12391 - crol CG12391 - DIP:21597N DIP:21597N - CG8301 DIP:21597N - CG12391 DIP:21597N - CG2202 DIP:21597N - crol DIP:21597N - CG8319 DIP:21597N - CG7386 DIP:21597N - CG7987 DIP:21597N - DIP:17897N DIP:21597N - CG4820 DIP:21597N - DIP:121N CG9797 - CG1792 CG9797 - CG7357 CG9797 - CG7386 CG9797 - CG8301 CG9797 - DIP:17897N CG9797 - CG31782 CG9797 - D19A CG9797 - CG10654 CG9797 - wdn CG9797 - CG18764 CG9797 - CG6808 CG9797 - CG7928 CG9797 - DIP:17378N CG9797 - CG2116 CG9797 - CG10267 CG9797 - opa CG9797 - CG2678 CG9797 - CG3281 CG9797 - l(2)35Ea CG9797 - CG17568 CG9797 - CG11696 CG9797 - CG10959 CG9797 - CG17802 CG9797 - CG7204 CG9797 - CG10274 CG9797 - CG4730 CG9797 - CG17801 CG9797 - CG18555 CG9797 - DIP:22012N CG9797 - CG6254 CG9797 - odd CG9797 - CG4820 CG9797 - CG31365 CG9797 - CG7987 CG13620 - CG10979 CG13620 - GI:24645129 sug - CTCF sug - CG18476 sug - CG4496 sug - l(2)35Ea sug - CG7368 sug - CG17568 sug - CG7987 sug - CG10274 sug - CG11695 sug - CG10348 sug - GI:17647565 rgr - l(2)35Ea rgr - CG9609 rgr - CG11696 rgr - CG10147 rgr - CG8301 rgr - CG7386 rgr - DIP:17897N rgr - CG10309 rgr - CG18476 rgr - Phol rgr - CG10543 rgr - CG3941 rgr - D19B rgr - CG10654 CG11902 - CG11696 DIP:22012N - CG6254 DIP:22012N - CG17801 DIP:22012N - CG9797 DIP:22012N - DIP:17378N DIP:22012N - CG17802 CG8301 - CG7928 CG8301 - DIP:17897N CG8301 - CG9797 CG8301 - l(2)35Ea CG8301 - CG10654 CG8301 - CG7386 CG8301 - CG17568 CG8301 - CkIIalpha-i1 CG8301 - D19A CG8301 - CG8319 CG8301 - DIP:17332N CG8301 - EG:95B7.7 CG8301 - CG4820 CG8301 - GI:24653568 CG8301 - CG4730 CG8301 - CG17801 CG8301 - CG10959 CG8301 - CG7101 CG8301 - CG2120 CG8301 - CG7752 CG8301 - opa CG8301 - CG1792 CG8301 - CG7357 CG8301 - CG31782 CG8301 - CG17802 CG8301 - CG7204 CG8301 - CG9609 CG8301 - CG11696 CG8301 - rgr CG8301 - CG10147 CG8301 - CG10309 CG8301 - CG18476 CG8301 - Phol CG8301 - CG10543 CG8301 - CG3941 CG8301 - D19B CG8301 - CG4360 CG8301 - CG4854 CG8301 - CG8388 CG8301 - CG3032 CG8301 - CG18764 CG8301 - drm CG8301 - CG10267 CG8301 - Aef1 CG8301 - CG10274 CG8301 - CG8145 CG8301 - odd CG8301 - CG7963 CG8301 - CG2116 CG8301 - CG12391 CG8301 - CG2202 CG8301 - crol CG8301 - DIP:21597N CG8301 - CG12942 CG8301 - CG8159 CG8301 - DIP:17378N CG8301 - CG2052 CG8301 - DIP:18586N CG4854 - CG4360 CG4854 - wdn CG4854 - CG17806 CG4854 - CG17568 CG4854 - CG8388 CG4854 - CG7386 CG4854 - CG8301 CG4854 - CG3032 CG4854 - CG18764 CG4854 - D19A CG4854 - drm CG4854 - CG10267 CG4854 - Aef1 CG4854 - CG10274 CG4936 - CG4730 CG4936 - EG:95B7.7 CG4936 - DIP:17897N CG4936 - CG17801 CG4936 - CG6689 CG4936 - CG10654 CG4936 - l(2)35Ea CG4936 - CG18764 CG4936 - CG7928 CG4936 - DIP:17378N CG4936 - CTCF CG4936 - CG7204 CG4936 - EG:BACR42I17.11 CG4936 - Sry-delta CG4936 - CG10147 CG4936 - CG11798 CG4936 - CG10309 CG4936 - su(Hw) CG4936 - CG18476 CG4936 - D19A CG4936 - CG10543 Sry-beta - CG8159 Sry-beta - CG6808 Sry-beta - CG3281 Sry-beta - CG7928 Sry-beta - CG2116 Sry-beta - CG17568 Sry-beta - CG18764 Sry-beta - CG10274 Sry-delta - EG:BACR42I17.11 Sry-delta - CG10147 Sry-delta - CG11798 Sry-delta - CG4936 Sry-delta - CG10309 Sry-delta - su(Hw) Sry-delta - CG18476 Sry-delta - D19A Sry-delta - CG10543 DIP:22634N - CG9650 DIP:22690N - CG17568 DIP:22690N - CG7386 DIP:22690N - CG8159 DIP:22690N - EP2237 CG1647 - CG7386 CG1647 - CG17801 CG1647 - CkIIalpha-i1 CG1647 - CG11696 CG1647 - CG15710 CG1647 - CG8159 CG18555 - CG9797 hkb - CG1792 hkb - DIP:19658N hkb - odd hkb - D19A hkb - opa hkb - CG7386 CTCF - CG17568 CTCF - sug CTCF - CG18476 CTCF - CG4496 CTCF - CG11798 CTCF - CG10543 CTCF - CG4936 CTCF - CG7928 CTCF - DIP:17378N CTCF - CG7386 CTCF - CG11695 CG7101 - drm CG7101 - CG8301 CG7101 - CG2120 CG7101 - CG9609 CG7101 - CG10979 CG3281 - CG7386 CG3281 - CG8159 CG3281 - DIP:17378N CG3281 - CG7928 CG3281 - CG9797 CG3281 - l(2)35Ea CG3281 - CG17568 CG3281 - CG11696 CG3281 - CG10959 CG3281 - CG18764 CG3281 - D19A CG3281 - CG17802 CG3281 - CG10267 CG3281 - CG7204 CG3281 - CG10274 CG3281 - CG7357 CG3281 - CG18011 CG3281 - CG17801 CG3281 - Sry-beta CG3281 - CG2116 CG4730 - DIP:17897N CG4730 - CG4936 CG4730 - CG17801 CG4730 - CG6689 CG4730 - CG10654 CG4730 - CG8301 CG4730 - CG9797 CG4730 - CG10959 CG4730 - EG:95B7.7 CG4730 - CG32767 CG4730 - CG10979 CG4730 - CG12942 CG4730 - CG7386 CG4730 - CG8159 CG4730 - CG7357 CG4730 - l(2)35Ea CG4730 - CG4820 DIP:23106N - CG8159 DIP:23106N - CG9793 CG7928 - CG7386 CG7928 - CG8319 CG7928 - DIP:17332N CG7928 - CG8301 CG7928 - EG:95B7.7 CG7928 - CG4820 CG7928 - GI:24653568 CG7928 - CG9793 CG7928 - DIP:17378N CG7928 - CG3281 CG7928 - CG9797 CG7928 - l(2)35Ea CG7928 - CG17568 CG7928 - CG11696 CG7928 - CG10959 CG7928 - CG18764 CG7928 - D19A CG7928 - CG17802 CG7928 - CG10267 CG7928 - CG7204 CG7928 - CG10274 CG7928 - CG15073 CG7928 - opa CG7928 - CG2116 CG7928 - CG6808 CG7928 - DIP:17897N CG7928 - CG10654 CG7928 - Sry-beta CG7928 - CG4936 CG7928 - CTCF CG7928 - CG11695 CG7928 - CG7987 CG12701 - CG7386 CG12701 - DIP:19658N CG7386 - CG7386 CG7386 - DIP:17378N CG7386 - CG7928 CG7386 - CG3281 CG7386 - CG9797 CG7386 - l(2)35Ea CG7386 - CG17568 CG7386 - CG11696 CG7386 - CG10959 CG7386 - CG18764 CG7386 - D19A CG7386 - CG17802 CG7386 - CG10267 CG7386 - CG7204 CG7386 - CG10274 CG7386 - CG7987 CG7386 - bowl CG7386 - odd CG7386 - CG18011 CG7386 - CG15073 CG7386 - CG4820 CG7386 - CG2678 CG7386 - CG31365 CG7386 - CG10462 CG7386 - CG8301 CG7386 - DIP:17897N CG7386 - CG12701 CG7386 - CG8319 CG7386 - DIP:21597N CG7386 - DIP:121N CG7386 - DIP:17332N CG7386 - EG:95B7.7 CG7386 - GI:24653568 CG7386 - CG8159 CG7386 - CG10654 CG7386 - CG1647 CG7386 - CG17801 CG7386 - CG1792 CG7386 - CG7357 CG7386 - CG31782 CG7386 - hkb CG7386 - DIP:19658N CG7386 - DIP:22690N CG7386 - EP2237 CG7386 - CG9609 CG7386 - rgr CG7386 - CG10147 CG7386 - CG10309 CG7386 - CG18476 CG7386 - Phol CG7386 - CG10543 CG7386 - CG3941 CG7386 - D19B CG7386 - CG4360 CG7386 - CG4854 CG7386 - CG8388 CG7386 - CG3032 CG7386 - drm CG7386 - Aef1 CG7386 - CG11247 CG7386 - CG4730 CG7386 - CG12942 CG7386 - CG9793 CG7386 - CG17612 CG7386 - CG11695 CG7386 - CTCF CG7386 - crol CG7357 - CG9797 CG7357 - CG2116 CG7357 - CG14711 CG7357 - CG3281 CG7357 - DIP:17378N CG7357 - CG18011 CG7357 - CG17801 CG7357 - CG10959 CG7357 - CG8159 CG7357 - CG1792 CG7357 - CG7386 CG7357 - CG8301 CG7357 - DIP:17897N CG7357 - CG31782 CG7357 - D19A CG7357 - CG10654 CG7357 - CG8145 CG7357 - CG17612 CG7357 - CG4730 CG7357 - l(2)35Ea CG7357 - CG4820 CG7357 - CG10147 CG7357 - CG2678 CG7357 - Aef1 CG10147 - CG9609 CG10147 - su(Hw) CG10147 - D19A CG10147 - CG11971 CG10147 - l(2)35Ea CG10147 - CG11696 CG10147 - rgr CG10147 - CG8301 CG10147 - CG7386 CG10147 - DIP:17897N CG10147 - CG10309 CG10147 - CG18476 CG10147 - Phol CG10147 - CG10543 CG10147 - CG3941 CG10147 - D19B CG10147 - CG10654 CG10147 - EG:BACR42I17.11 CG10147 - Sry-delta CG10147 - CG11798 CG10147 - CG4936 CG10147 - CG18764 CG10147 - CG7357 CG1832 - CG7987 CG1832 - CG18262 CG1832 - crol CG1832 - CG10543 CG1832 - CG11971 CG1832 - D19B CG17806 - CG4854 zfh1 - DIP:18586N zfh1 - CG2052 zfh1 - odd zfh1 - CG8145 CG7963 - CG1792 CG7963 - CG8301 CG7963 - CG2116 CG7963 - CG10267 CG8145 - CG10348 CG8145 - CG7357 CG8145 - zfh1 CG8145 - CG8301 CG8145 - CG17801 CG8145 - opa CG1792 - CG1792 CG1792 - CG9797 CG1792 - CG18764 CG1792 - CG8159 CG1792 - DIP:19658N CG1792 - hkb CG1792 - odd CG1792 - opa CG1792 - CG7357 CG1792 - CG7386 CG1792 - CG8301 CG1792 - DIP:17897N CG1792 - CG31782 CG1792 - D19A CG1792 - CG10654 CG1792 - CG7963 CG1792 - CG2116 CG1792 - CG10267 CG1792 - CG9793 CG8319 - CG7928 CG8319 - CG15073 CG8319 - CG17802 CG8319 - opa CG8319 - CG7386 CG8319 - CG7987 CG8319 - DIP:21597N CG8319 - DIP:17897N CG8319 - CG4820 CG8319 - DIP:121N CG8319 - DIP:17332N CG8319 - CG8301 CG8319 - EG:95B7.7 CG8319 - GI:24653568 CG8319 - l(2)35Ea CG8319 - CG11247 CG8319 - crol CG8319 - CG10654 CG8319 - CG10979 CG11798 - CG2116 CG11798 - CG7987 CG11798 - CTCF CG11798 - CG10543 CG11798 - EG:BACR42I17.11 CG11798 - Sry-delta CG11798 - CG10147 CG11798 - CG4936 CG11798 - CG10309 CG11798 - su(Hw) CG11798 - CG18476 CG11798 - D19A CG11798 - CG17568 CG11798 - CG40145 CG14962 - CG7987 CG14962 - CG33213 CG8388 - CG17568 CG8388 - CG4360 CG8388 - CG4854 CG8388 - CG7386 CG8388 - CG8301 CG8388 - CG3032 CG8388 - CG18764 CG8388 - D19A CG8388 - drm CG8388 - CG10267 CG8388 - Aef1 CG8388 - CG10274 CG8388 - DIP:18586N CG8388 - CG2052	Nrg2 - MIG1 Nrg2 - Nrg1p Swi5 - MIG1 Swi5 - Ace2 ADR1 - MIG1 ADR1 - Ace2 ADR1 - Ygr067c ADR1 - Yer028c Ydr437w - Msn4p Yer028c - Ygr067c Yer028c - MIG1 Yer028c - ADR1 MIG1 - ADR1 MIG1 - Ygr067c MIG1 - Yer028c MIG1 - Nrg1p MIG1 - Nrg2 MIG1 - Swi5 Ygr067c - MIG1 Ygr067c - Yer028c Ygr067c - ADR1 Ygr067c - DIP:6487N RIM101 - Zap1 Met32p - Met31 Nrg1p - MIG1 Nrg1p - Nrg2 Zap1 - RIM101 Ace2 - ADR1 Ace2 - Swi5 Met31 - Met32p DIP:6487N - Ygr067c Msn4p - Ydr437w
KOG0594 - KOG1721	CDC2 - KLF6 CDC2 - Sp1 CDC2 - YY1 CDK4 - OSR1 CDK4 - KLF6 CDK4 - PLAG1 CDK4 - HIVEP1 CDK4 - SIP1 CDK4 - ZNF83 CDK4 - FLJ12586 CDK4 - PLAGL1 CDK4 - PRDM4 CDK4 - PLZF CDK4 - Sp1 CDK6 - OSR1 CDK6 - KLF6 CDK2 - KLF6 CDK2 - PLAG1 CDK2 - HIVEP1 CDK2 - SIP1 CDK2 - ZNF83 CDK2 - FLJ12586 CDK2 - PLAGL1 CDK2 - PRDM4 CDK2 - PLZF CDK2 - Sp1 PFTK1 - OSR1	CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543 cdc2 - sug	Cdc28 - Swi5 Cdc28 - Ace2 Cdc28 - Crz1p Cdc28 - DIP:6487N Cdc28 - Ygr067c Cdc28 - RIM101 Cdc28 - Nrg2 Cak1 - Swi5 Cak1 - Ace2
KOG0627 - KOG1721	HSF1 - ZNF7	Hsf - CG12744	MGA1 - Fzf1 Hsf1p - Crz1p SKN7 - Crz1p SFL1 - MIG1 SFL1 - Nrg1p
KOG0643 - KOG1721	FLJ11294 - OSR1 TRIP1 - DIP:5990N TRIP1 - Miz-1	Trip1 - DIP:18586N Trip1 - CG2052	Tif34 - Ace2 Tif34 - ADR1
KOG0578 - KOG1721	PAK - OSR1 PAK - SIP1 PAK - IMAGE 3948563 PAK - KIAA0972 PAK - ZNF76	PAK - CG7386 PAK - CG7928 PAK - DIP:17378N PAK - CG9797 PAK - CG2116 PAK - CG6808 PAK - CG10267 PAK - opa PAK - CG3281 PAK - l(2)35Ea PAK - CG17568 PAK - CG11696 PAK - CG10959 PAK - CG18764 PAK - D19A PAK - CG17802 PAK - CG7204 PAK - CG10274 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	Ste20 - ADR1 Ste20 - Ygr067c Cla4 - Rgm1 Cla4 - Swi5 Cla4 - Ace2
KOG1113 - KOG1721	PRKAR1A - SIP1 PRKAR1A - COASTER PRKAR1A - RLF	DIP:17163N - l(2)35Ea DIP:17163N - DIP:17332N DIP:17163N - GI:24653568 DIP:17163N - EG:BACR42I17.11 DIP:17163N - Sry-delta DIP:17163N - CG10147 DIP:17163N - CG11798 DIP:17163N - CG4936 DIP:17163N - CG10309 DIP:17163N - su(Hw) DIP:17163N - CG18476 DIP:17163N - D19A DIP:17163N - CG10543 Pka-R2 - CG12701 For - l(2)35Ea For - DIP:17332N For - GI:24653568	Bcy1 - Fzf1 Bcy1 - Ace2 Bcy1 - ADR1
KOG1453 - KOG1721	CHN1 - OSR1 CHN2 - OSR1	DIP:18261N - CG8301 DIP:18261N - CG11696 DIP:18261N - CkIIalpha-i1 DIP:18261N - D19A	RGA1 - Swi5 RGA1 - Ace2 Rga1 - ADR1 Rga1 - Swi5 Rga1 - Ace2
KOG0583 - KOG1721	STK22D - OSR1	PNG - CG4730 PNG - DIP:17897N PNG - CG4936 PNG - CG17801 PNG - CG6689 PNG - CG10654 PNG - opa PNG - CG4820 Par-1 - CG10979 SNF1A - CG7752 trbl - CG7386 trbl - CG8301 trbl - CG17568 trbl - CG10654 trbl - CG14655 trbl - DIP:17897N trbl - CG9797 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	Snf1 - MIG1 Snf1 - Nrg1p Snf1 - Nrg2 Kcc4 - Ygr067c Kcc4 - MIG1 Kcc4 - Yer028c Kcc4 - ADR1 Ksp1p - Ace2 Kin2 - Fzf1 Kin2 - ADR1 Kin2 - Swi5 Kin2 - Ace2 Ypl141c - MIG1 Ypl141c - ADR1 Ypl141c - Ygr067c Ypl141c - Yer028c Ptk2p - Swi5 Ptk2p - Ace2
KOG0837 - KOG1721	JunD - YY1 JunD - Sp1 JUNB - Sp1 JUNB - DIP:5990N JUNB - Miz-1 JUNB - YY1 c-Jun - YY1 c-Jun - DIP:5990N c-Jun - Miz-1 c-Jun - Sp1	Jra - CG7357 Jra - CG11798 Jra - CG40145 Jra - Aef1	Gcn4 - Met31 Gcn4 - Swi5 Gcn4 - ADR1
KOG0712 - KOG1721	Ydj1p - DIP:5990N	CG8863 - D19A CG8863 - l(2)35Ea CG8863 - DIP:17332N CG8863 - GI:24653568 CG8863 - CG11696 CG8863 - CG7386 CG8863 - CG11247 CG8863 - CG9797 CG8863 - odd	Xdj1 - MIG1
KOG1450 - KOG1721	ARHGAP9 - E4F1 ARHGAP9 - ZF6 ARHGAP9 - SIP1 ARHGAP9 - ZNF83 ARHGAP9 - FLJ20765	DIP:17235N - CG1647 DIP:17235N - CG7386 DIP:17235N - CG17801 DIP:17235N - CG3281 DIP:17235N - CG7357 DIP:17235N - DIP:17378N DIP:17235N - CG18011 DIP:17235N - CG10959 DIP:17235N - CG8159 DIP:17235N - DIP:18586N DIP:17235N - CG2052	Rgd1 - RIM101
KOG1463 - KOG1721	PSMD11 - PLAG1 PSMD11 - HIVEP1 PSMD11 - SIP1 PSMD11 - ZNF83 PSMD11 - FLJ12586 PSMD11 - PLAGL1 PSMD11 - PRDM4 PSMD11 - PLZF PSMD11 - IMAGE 3948563 PSMD11 - KIAA0972 PSMD11 - ZNF76	Rpn6 - DIP:19658N Rpn6 - CG14451 Rpn6 - CG11247 Rpn6 - DIP:19658N Rpn6 - CG14451	Rpn6 - Ygr067c Rpn6 - Met31
KOG0929 - KOG1721	BIG1 - HIVEP1 BIG1 - ZNF510 BIG2 - COASTER BIG2 - RLF	loner - CG11696 loner - CG11695 loner - su(Hw)	SEC7 - MIG1 SEC7 - Nrg1p SEC7 - Nrg2
KOG1076 - KOG1721	EIF3S8 - COASTER EIF3S8 - E4F1 EIF3S8 - ZF6 EIF3S8 - SIP1 EIF3S8 - ZNF83 EIF3S8 - FLJ20765	eIF3-S8 - jing eIF3-S8 - CG7752 eIF3-S8 - opa	Nip1 - Fzf1 Nip1 - Ace2 Nip1 - ADR1
KOG1597 - KOG1721	TFIIB - DIP:36N TFIIB - YY1 TFIIB - Egr1	TfIIB - CG1832 TfIIB - CG18262 TfIIB - crol TfIIB - CG10543 TfIIB - CG11971 TfIIB - D19B	DIP:1077N - Swi5 TFIIB - Ace2 TFIIB - ADR1
KOG1124 - KOG1721	UTX - E4F1 UTX - ZF6 UTX - SIP1 UTX - ZNF83 UTX - FLJ20765	CG4341 - DIP:121N	Cyc8 - MIG1 Cyc8 - Nrg1p Cyc8 - DIP:150N Tah1 - Ygr067c Tah1 - MIG1 Tah1 - Yer028c Tah1 - ADR1
KOG1561 - KOG1721	NF-YA - Sp1 NF-YA - Egr1 NF-YA - PLZF	CG3891 - opa CG3891 - CG12744	HAP2 - Swi5 HAP2 - DIP:6487N HAP2 - Crz1p
KOG0580 - KOG1721	STK6 - YY1 HsAIRK-2 - OSR1	Pk61C - CG7386 Pk61C - CG10979 DIP:20399N - CG10462 DIP:20399N - CG7386 DIP:20399N - CG10979 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	Ipl1 - Swi5 Ipl1 - Ace2
KOG1721 - KOG3484	KLF6 - CKS1B	opa - CG9790 sug - DIP:102N sug - CG9790 Sqz - CG9790 zfh1 - CG9790	Swi5 - DIP:102N Swi5 - CKS1 Ace2 - DIP:102N Ace2 - CKS1

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Conserved subnet 3:
54 conserved interactions between 40 ortholog groups.
This subnet exists in 3 organisms (p<2e-137).

Ortholog Groups
KOG3863	bZIP transcription factor NRF1
KOG4196	bZIP transcription factor MafK
KOG1636	DNA polymerase delta processivity factor (proliferating cell nuclear antigen)
KOG4743	Cyclin-dependent kinase inhibitor
KOG0653	Cyclin B and related kinase-activating proteins
KOG4047	Docking protein 1 (p62dok)
KOG4271	Rho-GTPase activating protein
KOG0660	Mitogen-activated protein kinase
KOG3960	Myogenic helix-loop-helix transcription factor
KOG3701	TGFbeta receptor signaling protein SMAD and related proteins
KOG0655	G1/S-specific cyclin E
KOG0656	G1/S-specific cyclin D
KOG0578	p21-activated serine/threonine protein kinase
KOG3529	Radixin, moesin and related proteins of the ERM family
KOG2070	Guanine nucleotide exchange factor
KOG0594	Protein kinase PCTAIRE and related kinases
KOG1935	Membrane protein Patched/PTCH
KOG1721	FOG: Zn-finger
KOG4333	Nuclear DEAF-1 related transcriptional regulator (suppressin) and related SAND domain proteins
KOG1048	Neural adherens junction protein Plakophilin and related Armadillo repeat proteins
KOG1500	Protein arginine N-methyltransferase CARM1
KOG0736	Peroxisome assembly factor 2 containing the AAA+-type ATPase domain
KOG2330	Splicing factor 3b, subunit 2
KOG3575	FOG: Hormone receptors
KOG2294	Transcription factor of the Forkhead/HNF3 family
HG10522	Homologene family 10522
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG2052	Activin A type IB receptor, serine/threonine protein kinase
KOG3653	Transforming growth factor beta/activin receptor subfamily of serine/threonine kinases
KOG1214	Nidogen and related basement membrane protein proteins
KOG1215	Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains
KOG1218	Proteins containing Ca2+-binding EGF-like domains
KOG1219	Uncharacterized conserved protein, contains laminin, cadherin and EGF domains
KOG1217	Fibrillins and related proteins containing Ca2+-binding EGF-like domains
KOG3209	WW domain-containing protein
HG8189	Homologene family 8189
KOG3509	Basement membrane-specific heparan sulfate proteoglycan (HSPG) core protein
KOG1836	Extracellular matrix glycoprotein Laminin subunits alpha and gamma
KOG3528	FOG: PDZ domain

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG3863 - KOG4196	NF-E2 p45 - MafK Bach2 - MafK Bach2 - MafG Bach1 - MafK Bach1 - MafG Nrf2 - MafK	NFE2L2 - MafK NFE2L2 - MafG BACH1 - MafG BACH1 - MafK BACH1 - c-Maf BACH1 - MafB p45 - MafK p45 - MafG BACH2 - MafK BACH2 - MafG BACH2 - MafB BACH2 - c-Maf NFE2L1 - MafK NFE2L1 - MafG NFE2L1 - MafB NFE2L1 - c-Maf	DIP:17497N - maf-S cnc - maf-S
KOG1636 - KOG4743	Pcna - p27	PCNA - Waf1 PCNA - p27	mus209 - DIP:22731N
KOG0653 - KOG1636	Cyclin B1 - Pcna	DIP:24234N - PCNA Cyclin B1 - PCNA	DIP:17624N - mus209
KOG4047 - KOG4271	Dok1 - p190-rhoGAP Dok2 - p190-rhoGAP	DOK1 - p190 Dok2 - p190	CG2079 - RhoGAPp190
KOG0660 - KOG3960	Mapk14 - MyoD	MAPK13 - MYOD1	CG30171 - nau
KOG0660 - KOG3701	Mapk14 - Smad3	MAPK13 - SMAD4 MAPK13 - Smad5 MAPK13 - Smad3 MAPK13 - Smad2 MAPK13 - Smad1	CG32703 - Mad
KOG0655 - KOG0656	Ccne1 - Cyclin D1 Ccne1 - Ccnd2	cyclin E - Cyclin D cycE - Cyclin D	CycE - CycD
KOG0578 - KOG3529	PAK1 - Nf2	PAK - Merlin PAK - ezrin	CG30171 - Mer CG30171 - Moe
KOG0578 - KOG4047	PAK1 - Dok2 PAK1 - Dok1	PAK - FRS2-alpha	CG30171 - CG2079
KOG0578 - KOG2070	PAK1 - Arhgef7	PAK - alpha-PIX PAK - Beta-PIX	PAK - rtGEF
KOG0594 - KOG0653	Cdk1 - Cyclin B1	CDC2 - cyclin B2 CDC2 - Cyclin B1 CDK4 - Cyclin B1 CDK2 - DIP:24234N CDK2 - Cyclin B1	Cdk4 - DIP:17624N CG30171 - CycG cdc2 - CycG
KOG0594 - KOG0655	CDK4 - Ccne1	CDC2 - cycE CDK2 - cycE	CG30171 - CycE cdc2 - CycE
KOG0594 - KOG0656	Cdk1 - Cyclin D1 Cdk1 - Ccnd2 Cdk6 - Cyclin D1 Cdk6 - Ccnd2 CDK4 - Cyclin D1 CDK4 - Ccnd2	DIP:648N - Cyclin D DIP:649N - Cyclin D DIP:686N - Cyclin D Cdc28p - Cyclin D CDC2 - Cyclin D CDK4 - CCND2 CDK4 - Cyclin D CDK6 - Cyclin D CDK6 - CCND2 CDK2 - Cyclin D CDK2 - CCND2	Cdk4 - CycD cdc2 - CycD
KOG0594 - KOG1935	Cdk1 - Ptc1	CDC2 - Ptc1	CG30171 - ptc
KOG1721 - KOG4333	ZAC1 - GMEB1	IMAGE 3948563 - GMEB1 PLZF - GMEB1 ZNF76 - GMEB1 ZNF83 - GMEB1 zid - GMEB1 PRDM4 - GMEB1 FLJ12586 - GMEB1 COASTER - GMEB1 SIP1 - GMEB1 KIAA0972 - GMEB1 HIVEP1 - GMEB1 PLAGL1 - GMEB1 PLAG1 - GMEB1	wdn - Deaf1 CG10979 - Deaf1 CG11247 - Deaf1 CG8159 - Deaf1 DIP:17378N - Deaf1 CG10959 - Deaf1 CG17801 - Deaf1 EG:95B7.7 - Deaf1 CG18011 - Deaf1 CG3281 - Deaf1 CG7357 - Deaf1
KOG1721 - KOG1721	Egr1 - Egr1	ZNF-U69274 - ZFD25 DIP:36N - YY1 FLJ20765 - E4F1 FLJ20765 - ZF6 FLJ20765 - SIP1 FLJ20765 - ZNF83 FLJ23392 - zid FLJ23392 - ZFP106 IMAGE 3948563 - SIP1 IMAGE 3948563 - KIAA0972 IMAGE 3948563 - ZNF76 YY1 - DIP:36N YY1 - AEBP2 YY1 - Egr1 Miz-1 - DIP:5990N Miz-1 - Sp1 PLZF - Sp1 PLZF - BCL6 PLZF - PLAG1 PLZF - HIVEP1 PLZF - SIP1 PLZF - ZNF83 PLZF - FLJ12586 PLZF - PLAGL1 PLZF - PRDM4 PLZF - Egr1 PLZF - zid ZFP106 - zid ZFP106 - FLJ23392 ZNF76 - IMAGE 3948563 ZNF76 - SIP1 ZNF76 - KIAA0972 MGC4054 - SIP1 ZNF83 - E4F1 ZNF83 - ZF6 ZNF83 - SIP1 ZNF83 - FLJ20765 ZNF83 - PLAG1 ZNF83 - HIVEP1 ZNF83 - FLJ12586 ZNF83 - PLAGL1 ZNF83 - PRDM4 ZNF83 - PLZF zid - BCL6 zid - ZFP106 zid - FLJ23392 zid - PLZF CTCF - DIP:5990N PRDM4 - PLAG1 PRDM4 - HIVEP1 PRDM4 - SIP1 PRDM4 - ZNF83 PRDM4 - FLJ12586 PRDM4 - PLAGL1 PRDM4 - PLZF AEBP2 - YY1 FLJ12586 - PLAG1 FLJ12586 - HIVEP1 FLJ12586 - SIP1 FLJ12586 - ZNF83 FLJ12586 - PLAGL1 FLJ12586 - PRDM4 FLJ12586 - PLZF COASTER - RLF SIP1 - E4F1 SIP1 - ZF6 SIP1 - ZNF83 SIP1 - FLJ20765 SIP1 - PLAG1 SIP1 - HIVEP1 SIP1 - FLJ12586 SIP1 - PLAGL1 SIP1 - PRDM4 SIP1 - PLZF SIP1 - MGC4054 SIP1 - IMAGE 3948563 SIP1 - KIAA0972 SIP1 - ZNF76 Egr1 - Sp1 Egr1 - PLZF Egr1 - YY1 DIP:5990N - Miz-1 DIP:5990N - CTCF KIAA0972 - IMAGE 3948563 KIAA0972 - SIP1 KIAA0972 - ZNF76 ZF6 - E4F1 ZF6 - SIP1 ZF6 - ZNF83 ZF6 - FLJ20765 ZFD25 - ZNF-U69274 HIVEP1 - PLAG1 HIVEP1 - SIP1 HIVEP1 - ZNF83 HIVEP1 - FLJ12586 HIVEP1 - PLAGL1 HIVEP1 - PRDM4 HIVEP1 - PLZF E4F1 - ZF6 E4F1 - SIP1 E4F1 - ZNF83 E4F1 - FLJ20765 RLF - COASTER BCL6 - BCL6 BCL6 - zid BCL6 - PLZF PLAGL1 - PLAG1 PLAGL1 - HIVEP1 PLAGL1 - SIP1 PLAGL1 - ZNF83 PLAGL1 - FLJ12586 PLAGL1 - PRDM4 PLAGL1 - PLZF Sp1 - Egr1 Sp1 - PLZF Sp1 - Miz-1 PLAG1 - HIVEP1 PLAG1 - SIP1 PLAG1 - ZNF83 PLAG1 - FLJ12586 PLAG1 - PLAGL1 PLAG1 - PRDM4 PLAG1 - PLZF	CG40145 - CG11798 wdn - CG4854 wdn - CG4360 wdn - CG11247 wdn - CG10979 wdn - DIP:18586N wdn - CG2052 wdn - CG9797 EP2237 - CG17568 EP2237 - DIP:22690N EP2237 - CG7386 EP2237 - CG8159 DIP:121N - CG17612 DIP:121N - D19A DIP:121N - CG1233 DIP:121N - CG10274 DIP:121N - CG8319 DIP:121N - CG7386 DIP:121N - CG7987 DIP:121N - DIP:21597N DIP:121N - DIP:17897N DIP:121N - CG4820 CG14655 - CG17568 opa - CG8319 opa - CG8145 opa - CG1792 opa - CG8301 opa - DIP:17332N opa - GI:24653568 opa - CG7752 opa - CG7928 opa - DIP:17378N opa - CG9797 opa - CG2116 opa - CG6808 opa - CG10267 opa - CG18476 opa - hkb opa - D19A opa - odd opa - CG15073 opa - CG17802 opa - DIP:19658N CG10274 - CG7386 CG10274 - CG8159 CG10274 - CG17568 CG10274 - CG4360 CG10274 - CG4854 CG10274 - CG8388 CG10274 - CG8301 CG10274 - CG3032 CG10274 - CG18764 CG10274 - D19A CG10274 - drm CG10274 - CG10267 CG10274 - Aef1 CG10274 - CG17612 CG10274 - CG1233 CG10274 - DIP:121N CG10274 - DIP:17378N CG10274 - CG7928 CG10274 - CG3281 CG10274 - CG9797 CG10274 - l(2)35Ea CG10274 - CG11696 CG10274 - CG10959 CG10274 - CG17802 CG10274 - CG7204 CG10274 - Sry-beta CG10274 - sug CG10274 - CG7987 CG7752 - CG8301 CG7752 - DIP:17332N CG7752 - GI:24653568 CG7752 - opa CG7752 - su(Hw) CG7752 - CG2678 CG7752 - CG10462 CG7752 - jing CG33213 - CG14451 CG33213 - CG14962 CG33213 - CG7987 CG33213 - CG18764 CG33213 - CG10267 CG33213 - CG17568 CG33213 - CG2116 CG33213 - CG18476 CG33213 - DIP:19928N Aef1 - CG17568 Aef1 - CG4360 Aef1 - CG4854 Aef1 - CG8388 Aef1 - CG7386 Aef1 - CG8301 Aef1 - CG3032 Aef1 - CG18764 Aef1 - D19A Aef1 - drm Aef1 - CG10267 Aef1 - CG10274 Aef1 - CG7357 Aef1 - CG2678 CG7204 - CG7386 CG7204 - l(2)35Ea CG7204 - EG:95B7.7 CG7204 - DIP:17378N CG7204 - CG7928 CG7204 - CG3281 CG7204 - CG9797 CG7204 - CG17568 CG7204 - CG11696 CG7204 - CG10959 CG7204 - CG18764 CG7204 - D19A CG7204 - CG17802 CG7204 - CG10267 CG7204 - CG10274 CG7204 - CG8301 CG7204 - CG4936 CG10267 - CG10267 CG10267 - CG7386 CG10267 - CG17568 CG10267 - CG4360 CG10267 - CG4854 CG10267 - CG8388 CG10267 - CG8301 CG10267 - CG3032 CG10267 - CG18764 CG10267 - D19A CG10267 - drm CG10267 - Aef1 CG10267 - CG10274 CG10267 - CG1792 CG10267 - CG7963 CG10267 - CG2116 CG10267 - CG10321 CG10267 - CG17385 CG10267 - CG17802 CG10267 - CG7928 CG10267 - DIP:17378N CG10267 - CG9797 CG10267 - CG6808 CG10267 - opa CG10267 - CG2889 CG10267 - CG33213 CG10267 - CG3281 CG10267 - l(2)35Ea CG10267 - CG11696 CG10267 - CG10959 CG10267 - CG7204 CG10267 - odd CG10267 - CG2052 CG10267 - DIP:18586N CG10979 - CG10462 CG10979 - CG4730 CG10979 - CG32767 CG10979 - CG7101 CG10979 - CG9609 CG10979 - CG13620 CG10979 - CG8319 CG10979 - CG11247 CG10979 - wdn CG10979 - CG17801 CG10979 - l(2)35Ea CG10979 - CG10654 CG10979 - CG8159 CG10979 - CG4820 CG10979 - DIP:17897N CG10654 - CG4730 CG10654 - CG8301 CG10654 - CG9797 CG10654 - CG17801 CG10654 - CG10959 CG10654 - DIP:17897N CG10654 - CG4936 CG10654 - CG6689 CG10654 - CG7386 CG10654 - CG17568 CG10654 - CG7928 CG10654 - l(2)35Ea CG10654 - CG1792 CG10654 - CG7357 CG10654 - CG31782 CG10654 - D19A CG10654 - CG4820 CG10654 - CG9609 CG10654 - CG11696 CG10654 - rgr CG10654 - CG10147 CG10654 - CG10309 CG10654 - CG18476 CG10654 - Phol CG10654 - CG10543 CG10654 - CG3941 CG10654 - D19B CG10654 - CG12942 CG10654 - CG8159 CG10654 - CG11247 CG10654 - crol CG10654 - CG8319 CG10654 - CG10979 CG6254 - DIP:22012N CG6254 - CG17801 CG6254 - CG9797 CG6254 - DIP:17378N CG6254 - CG17802 CG11247 - CG17802 CG11247 - CG10979 CG11247 - wdn CG11247 - CG11696 CG11247 - CG7386 CG11247 - DIP:17897N CG11247 - CG4820 CG11247 - CG10654 CG11247 - CG8319 CG11247 - l(2)35Ea D19B - l(2)35Ea D19B - CG14441 D19B - CG1832 D19B - CG18262 D19B - crol D19B - CG10543 D19B - CG11971 D19B - CG9609 D19B - CG11696 D19B - rgr D19B - CG10147 D19B - CG8301 D19B - CG7386 D19B - DIP:17897N D19B - CG10309 D19B - CG18476 D19B - Phol D19B - CG10543 D19B - CG3941 D19B - CG10654 D19B - D19A D19B - CG18764 D19B - CG8159 drm - CG7101 drm - CG17568 drm - CG4360 drm - CG4854 drm - CG8388 drm - CG7386 drm - CG8301 drm - CG3032 drm - CG18764 drm - D19A drm - CG10267 drm - Aef1 drm - CG10274 odd - D19A odd - CG14711 odd - l(2)35Ea odd - CG7386 odd - CG9797 odd - bowl odd - CG11695 odd - CG8301 odd - CG10267 odd - zfh1 odd - DIP:18586N odd - CG2052 odd - CG1792 odd - DIP:19658N odd - hkb odd - opa odd - CG2889 odd - CG8159 bowl - CG7386 bowl - odd CG14451 - CG33213 jim - CG14711 CG17612 - CG7357 CG17612 - CG7386 CG17612 - CG8159 CG17612 - D19A CG17612 - CG1233 CG17612 - DIP:121N CG17612 - CG10274 CG3941 - l(2)35Ea CG3941 - CG9609 CG3941 - CG11696 CG3941 - rgr CG3941 - CG10147 CG3941 - CG8301 CG3941 - CG7386 CG3941 - DIP:17897N CG3941 - CG10309 CG3941 - CG18476 CG3941 - Phol CG3941 - CG10543 CG3941 - D19B CG3941 - CG10654 CG2052 - zfh1 CG2052 - DIP:18586N CG2052 - odd CG2052 - CG8388 CG2052 - wdn CG2052 - CG8301 CG2052 - CG10267 GI:24645129 - CG13620 CG8159 - CG3281 CG8159 - Sry-beta CG8159 - CG17568 CG8159 - CG18764 CG8159 - CG8159 CG8159 - CG10274 CG8159 - CG7386 CG8159 - CG7357 CG8159 - DIP:17378N CG8159 - CG18011 CG8159 - CG17801 CG8159 - CG10959 CG8159 - CG1647 CG8159 - DIP:20799N CG8159 - DIP:22690N CG8159 - EP2237 CG8159 - CG4730 CG8159 - CG8301 CG8159 - CG12942 CG8159 - DIP:17897N CG8159 - CG10654 CG8159 - CG1792 CG8159 - CG9793 CG8159 - CG17612 CG8159 - D19A CG8159 - D19B CG8159 - CG2889 CG8159 - odd CG8159 - CG10979 CG8159 - CG4820 CG8159 - DIP:23106N CG9793 - CG18764 CG9793 - CG7928 CG9793 - CG1792 CG9793 - CG7386 CG9793 - CG8159 CG9793 - DIP:23106N CG17802 - CG8319 CG17802 - CG7386 CG17802 - l(2)35Ea CG17802 - CG11247 CG17802 - CG7928 CG17802 - CG15073 CG17802 - opa CG17802 - CG18011 CG17802 - CG4820 CG17802 - DIP:17378N CG17802 - CG3281 CG17802 - CG9797 CG17802 - CG17568 CG17802 - CG11696 CG17802 - CG10959 CG17802 - CG18764 CG17802 - D19A CG17802 - CG10267 CG17802 - CG7204 CG17802 - CG10274 CG17802 - CG10321 CG17802 - CG17385 CG17802 - CG8301 CG17802 - CG17801 CG17802 - DIP:22012N CG17802 - CG6254 CG11971 - CG10147 CG11971 - CG1832 CG11971 - CG18262 CG11971 - crol CG11971 - CG10543 CG11971 - D19B CG9650 - DIP:22634N CG16779 - CG2678 CG16779 - CG10543 DIP:17332N - CG7928 DIP:17332N - GI:24653568 DIP:17332N - CG7386 DIP:17332N - CG8319 DIP:17332N - CG8301 DIP:17332N - EG:95B7.7 DIP:17332N - CG4820 DIP:17332N - CG7752 DIP:17332N - opa DIP:17332N - l(2)35Ea DIP:17378N - CG7386 DIP:17378N - CG10462 DIP:17378N - CG6808 DIP:17378N - CG7928 DIP:17378N - CG3281 DIP:17378N - CG9797 DIP:17378N - l(2)35Ea DIP:17378N - CG17568 DIP:17378N - CG11696 DIP:17378N - CG10959 DIP:17378N - CG18764 DIP:17378N - D19A DIP:17378N - CG17802 DIP:17378N - CG10267 DIP:17378N - CG7204 DIP:17378N - CG10274 DIP:17378N - CG2116 DIP:17378N - opa DIP:17378N - CG7357 DIP:17378N - CG18011 DIP:17378N - CG17801 DIP:17378N - CG8159 DIP:17378N - CG4936 DIP:17378N - CTCF DIP:17378N - DIP:22012N DIP:17378N - CG6254 DIP:17378N - CG8301 DIP:17378N - CG4820 DIP:17378N - CG7987 GI:24653568 - CG7928 GI:24653568 - CG7386 GI:24653568 - CG8319 GI:24653568 - DIP:17332N GI:24653568 - CG8301 GI:24653568 - EG:95B7.7 GI:24653568 - CG4820 GI:24653568 - l(2)35Ea GI:24653568 - CG7752 GI:24653568 - opa CG17385 - CG10321 CG17385 - CG17802 CG17385 - CG10267 CG17385 - D19A CG10543 - CG1832 CG10543 - CG18262 CG10543 - crol CG10543 - CG11971 CG10543 - D19B CG10543 - CTCF CG10543 - CG11798 CG10543 - l(2)35Ea CG10543 - CG9609 CG10543 - CG11696 CG10543 - rgr CG10543 - CG10147 CG10543 - CG8301 CG10543 - CG7386 CG10543 - DIP:17897N CG10543 - CG10309 CG10543 - CG18476 CG10543 - Phol CG10543 - CG3941 CG10543 - D19B CG10543 - CG10654 CG10543 - CG2678 CG10543 - CG16779 CG10543 - EG:BACR42I17.11 CG10543 - Sry-delta CG10543 - CG4936 CG10543 - su(Hw) CG10543 - D19A MTF-1 - DIP:19181N CG4496 - CG2116 CG4496 - CTCF CG4496 - sug CG4496 - CG18476 Phol - l(2)35Ea Phol - CG9609 Phol - CG11696 Phol - rgr Phol - CG10147 Phol - CG8301 Phol - CG7386 Phol - DIP:17897N Phol - CG10309 Phol - CG18476 Phol - CG10543 Phol - CG3941 Phol - D19B Phol - CG10654 Phol - pho CG4820 - CG7928 CG4820 - CG7386 CG4820 - CG18011 CG4820 - CG15073 CG4820 - CG17802 CG4820 - CG7987 CG4820 - DIP:17332N CG4820 - GI:24653568 CG4820 - DIP:19928N CG4820 - DIP:17897N CG4820 - CG10654 CG4820 - CG8319 CG4820 - CG8301 CG4820 - EG:95B7.7 CG4820 - CG11247 CG4820 - CG10366 CG4820 - DIP:21597N CG4820 - DIP:121N CG4820 - CG7357 CG4820 - CG4730 CG4820 - l(2)35Ea CG4820 - CG9797 CG4820 - CG2116 CG4820 - DIP:17378N CG4820 - crol CG4820 - CG2678 CG4820 - CG10979 CG4820 - CG8159 CG6689 - CG4730 CG6689 - DIP:17897N CG6689 - CG4936 CG6689 - CG17801 CG6689 - CG10654 D19A - l(2)35Ea D19A - CG7386 D19A - CG9797 D19A - odd D19A - CG17801 D19A - CG17568 D19A - CG4360 D19A - CG4854 D19A - CG8388 D19A - CG8301 D19A - CG3032 D19A - CG18764 D19A - drm D19A - CG10267 D19A - Aef1 D19A - CG10274 D19A - hkb D19A - opa D19A - CG10959 D19A - CG17802 D19A - CG7204 D19A - CkIIalpha-i1 D19A - CG2116 D19A - DIP:17378N D19A - CG7928 D19A - CG3281 D19A - CG11696 D19A - CG17385 D19A - CG15336 D19A - CG1792 D19A - CG7357 D19A - DIP:17897N D19A - CG31782 D19A - CG10654 D19A - EG:BACR42I17.11 D19A - Sry-delta D19A - CG10147 D19A - CG11798 D19A - CG4936 D19A - CG10309 D19A - su(Hw) D19A - CG18476 D19A - CG10543 D19A - CG9609 D19A - DIP:19658N D19A - EG:95B7.7 D19A - CG17612 D19A - CG1233 D19A - DIP:121N D19A - D19B D19A - CG8159 DIP:17897N - CG4730 DIP:17897N - CG8301 DIP:17897N - CG9797 DIP:17897N - CG17801 DIP:17897N - CG10959 DIP:17897N - CG10654 DIP:17897N - CG4936 DIP:17897N - CG6689 DIP:17897N - CG7928 DIP:17897N - l(2)35Ea DIP:17897N - CG7386 DIP:17897N - CG1792 DIP:17897N - CG7357 DIP:17897N - CG31782 DIP:17897N - D19A DIP:17897N - CG4820 DIP:17897N - CG9609 DIP:17897N - CG11696 DIP:17897N - rgr DIP:17897N - CG10147 DIP:17897N - CG10309 DIP:17897N - CG18476 DIP:17897N - Phol DIP:17897N - CG10543 DIP:17897N - CG3941 DIP:17897N - D19B DIP:17897N - CG12942 DIP:17897N - CG8159 DIP:17897N - CG11247 DIP:17897N - CG8319 DIP:17897N - CG7987 DIP:17897N - DIP:21597N DIP:17897N - DIP:121N DIP:17897N - CG17568 DIP:17897N - CG10979 CG6808 - DIP:17378N CG6808 - CG9797 CG6808 - CG7928 CG6808 - CG2116 CG6808 - CG10267 CG6808 - opa CG6808 - Sry-beta CG14711 - CG15710 CG14711 - odd CG14711 - l(2)35Ea CG14711 - jim CG14711 - CG7357 CG18764 - CG1792 CG18764 - CG7386 CG18764 - CG9793 CG18764 - CG8159 CG18764 - CG17568 CG18764 - CG4360 CG18764 - CG4854 CG18764 - CG8388 CG18764 - CG8301 CG18764 - CG3032 CG18764 - D19A CG18764 - drm CG18764 - CG10267 CG18764 - Aef1 CG18764 - CG10274 CG18764 - CG9797 CG18764 - CG4936 CG18764 - l(2)35Ea CG18764 - EG:95B7.7 CG18764 - CG33213 CG18764 - DIP:17378N CG18764 - CG7928 CG18764 - CG3281 CG18764 - CG11696 CG18764 - CG10959 CG18764 - CG17802 CG18764 - CG7204 CG18764 - CG10147 CG18764 - Sry-beta CG18764 - D19B CG18476 - CG9609 CG18476 - CTCF CG18476 - sug CG18476 - CG4496 CG18476 - l(2)35Ea CG18476 - CG11696 CG18476 - rgr CG18476 - CG10147 CG18476 - CG8301 CG18476 - CG7386 CG18476 - DIP:17897N CG18476 - CG10309 CG18476 - Phol CG18476 - CG10543 CG18476 - CG3941 CG18476 - D19B CG18476 - CG10654 CG18476 - EG:BACR42I17.11 CG18476 - Sry-delta CG18476 - CG11798 CG18476 - CG4936 CG18476 - su(Hw) CG18476 - D19A CG18476 - CG17568 CG18476 - CG2116 CG18476 - DIP:19928N CG18476 - CG33213 CG18476 - opa CG15710 - CG14711 CG15710 - CG1647 CG15710 - CkIIalpha-i1 CG15710 - CG11696 CG31782 - CG9797 CG31782 - CG1792 CG31782 - CG7357 CG31782 - CG7386 CG31782 - CG8301 CG31782 - DIP:17897N CG31782 - D19A CG31782 - CG10654 DIP:18586N - zfh1 DIP:18586N - CG2052 DIP:18586N - odd DIP:18586N - CG8388 DIP:18586N - wdn DIP:18586N - CG8301 DIP:18586N - CG10267 pho - Phol pho - CG3032 CG10959 - l(2)35Ea CG10959 - CG7386 CG10959 - DIP:17897N CG10959 - CG10654 CG10959 - CG8301 CG10959 - D19A CG10959 - CG17802 CG10959 - CG7204 CG10959 - CG3281 CG10959 - CG7357 CG10959 - DIP:17378N CG10959 - CG18011 CG10959 - CG17801 CG10959 - CG8159 CG10959 - CG7928 CG10959 - CG9797 CG10959 - CG17568 CG10959 - CG11696 CG10959 - CG18764 CG10959 - CG10267 CG10959 - CG10274 CG10959 - CG4730 CG10959 - CG2129 su(Hw) - CG11696 su(Hw) - CG11695 su(Hw) - EG:BACR42I17.11 su(Hw) - Sry-delta su(Hw) - CG10147 su(Hw) - CG11798 su(Hw) - CG4936 su(Hw) - CG10309 su(Hw) - CG18476 su(Hw) - D19A su(Hw) - CG10543 su(Hw) - CG7752 su(Hw) - CG18262 su(Hw) - CG9609 CG1233 - CG17612 CG1233 - D19A CG1233 - DIP:121N CG1233 - CG10274 CG2129 - CG2129 CG2129 - CG11696 CG2129 - CG10959 CG7987 - CG1832 CG7987 - CG7386 CG7987 - CG17568 CG7987 - CG4820 CG7987 - CG11798 CG7987 - CG2116 CG7987 - CG14962 CG7987 - CG33213 CG7987 - sug CG7987 - CG10274 CG7987 - CG8319 CG7987 - DIP:21597N CG7987 - DIP:17897N CG7987 - DIP:121N CG7987 - CG7928 CG7987 - DIP:17378N CG7987 - CG9797 CG7368 - sug DIP:18917N - ovo crol - CG1832 crol - CG18262 crol - CG10543 crol - CG11971 crol - D19B crol - CG8301 crol - CG12391 crol - CG2202 crol - DIP:21597N crol - CG4820 crol - CG8319 crol - CG7386 crol - CG10654 CG15073 - CG8319 CG15073 - CG7386 CG15073 - CG18011 CG15073 - CG4820 CG15073 - CG17802 CG15073 - CG7928 CG15073 - opa DIP:19181N - MTF-1 CG10309 - l(2)35Ea CG10309 - CG9609 CG10309 - CG11696 CG10309 - rgr CG10309 - CG10147 CG10309 - CG8301 CG10309 - CG7386 CG10309 - DIP:17897N CG10309 - CG18476 CG10309 - Phol CG10309 - CG10543 CG10309 - CG3941 CG10309 - D19B CG10309 - CG10654 CG10309 - EG:BACR42I17.11 CG10309 - Sry-delta CG10309 - CG11798 CG10309 - CG4936 CG10309 - su(Hw) CG10309 - D19A ovo - DIP:18917N CG32767 - CG4730 CG32767 - CG10979 DIP:19658N - CG1792 DIP:19658N - hkb DIP:19658N - odd DIP:19658N - CG7386 DIP:19658N - CG12701 DIP:19658N - D19A DIP:19658N - opa CG17801 - CG4730 CG17801 - DIP:17897N CG17801 - CG10654 CG17801 - CG4936 CG17801 - CG6689 CG17801 - CG3281 CG17801 - CG7357 CG17801 - DIP:17378N CG17801 - CG18011 CG17801 - CG10959 CG17801 - CG8159 CG17801 - CG8301 CG17801 - D19A CG17801 - CG1647 CG17801 - CG7386 CG17801 - CG9797 CG17801 - CG8145 CG17801 - DIP:22012N CG17801 - CG17802 CG17801 - CG6254 CG17801 - CG12942 CG17801 - CG10979 CG17801 - l(2)35Ea GI:17647565 - sug GI:17647565 - CG10348 DIP:19928N - CG4820 DIP:19928N - CG17568 DIP:19928N - CG2116 DIP:19928N - CG18476 DIP:19928N - CG33213 CG14441 - D19B CG3032 - CG17568 CG3032 - CG4360 CG3032 - CG4854 CG3032 - CG8388 CG3032 - CG7386 CG3032 - CG8301 CG3032 - CG18764 CG3032 - D19A CG3032 - drm CG3032 - CG10267 CG3032 - Aef1 CG3032 - CG10274 CG3032 - pho CG10348 - CG8145 CG10348 - sug CG10348 - GI:17647565 CG4360 - CG4854 CG4360 - wdn CG4360 - CG17568 CG4360 - CG8388 CG4360 - CG7386 CG4360 - CG8301 CG4360 - CG3032 CG4360 - CG18764 CG4360 - D19A CG4360 - drm CG4360 - CG10267 CG4360 - Aef1 CG4360 - CG10274 CG2116 - CG10462 CG2116 - CG3281 CG2116 - Sry-beta CG2116 - CG7928 CG2116 - DIP:17378N CG2116 - CG9797 CG2116 - CG6808 CG2116 - CG10267 CG2116 - opa CG2116 - D19A CG2116 - CG17568 CG2116 - CG18476 CG2116 - DIP:19928N CG2116 - CG33213 CG2116 - CG11798 CG2116 - CG7987 CG2116 - CG7357 CG2116 - CG4496 CG2116 - CG1792 CG2116 - CG7963 CG2116 - CG8301 CG2116 - CG4820 CG2120 - CkIIalpha-i1 CG2120 - CG7101 CG2120 - CG8301 CG15336 - D19A CG18262 - CG1832 CG18262 - crol CG18262 - CG10543 CG18262 - CG11971 CG18262 - D19B CG18262 - CG11696 CG18262 - su(Hw) CG11696 - CG7386 CG11696 - CG11902 CG11696 - CG1647 CG11696 - CkIIalpha-i1 CG11696 - CG15710 CG11696 - DIP:17378N CG11696 - CG7928 CG11696 - CG3281 CG11696 - CG9797 CG11696 - l(2)35Ea CG11696 - CG17568 CG11696 - CG10959 CG11696 - CG18764 CG11696 - D19A CG11696 - CG17802 CG11696 - CG10267 CG11696 - CG7204 CG11696 - CG10274 CG11696 - CG18262 CG11696 - su(Hw) CG11696 - CG9609 CG11696 - rgr CG11696 - CG10147 CG11696 - CG8301 CG11696 - DIP:17897N CG11696 - CG10309 CG11696 - CG18476 CG11696 - Phol CG11696 - CG10543 CG11696 - CG3941 CG11696 - D19B CG11696 - CG10654 CG11696 - CG11695 CG11696 - CG2129 CG11696 - CG11247 CG17568 - CG7386 CG17568 - DIP:22690N CG17568 - CG8159 CG17568 - EP2237 CG17568 - CG7987 CG17568 - CG14655 CG17568 - CG8301 CG17568 - CG10654 CG17568 - DIP:17378N CG17568 - CG7928 CG17568 - CG3281 CG17568 - CG9797 CG17568 - l(2)35Ea CG17568 - CG11696 CG17568 - CG10959 CG17568 - CG18764 CG17568 - D19A CG17568 - CG17802 CG17568 - CG10267 CG17568 - CG7204 CG17568 - CG10274 CG17568 - CTCF CG17568 - CG2116 CG17568 - CG18476 CG17568 - DIP:19928N CG17568 - CG33213 CG17568 - DIP:17897N CG17568 - sug CG17568 - CG4360 CG17568 - CG4854 CG17568 - CG8388 CG17568 - CG3032 CG17568 - drm CG17568 - Aef1 CG17568 - CG11798 CG17568 - Sry-beta CG10366 - CG4820 CG10462 - DIP:17378N CG10462 - CG2116 CG10462 - CG10979 CG10462 - CG7386 CG10462 - CG2678 CG10462 - CG7752 CG10631 - CG12391 CG12942 - CG4730 CG12942 - CG8301 CG12942 - CG17801 CG12942 - CG7386 CG12942 - DIP:17897N CG12942 - CG8159 CG12942 - CG10654 EG:BACR42I17.11 - Sry-delta EG:BACR42I17.11 - CG10147 EG:BACR42I17.11 - CG11798 EG:BACR42I17.11 - CG4936 EG:BACR42I17.11 - CG10309 EG:BACR42I17.11 - su(Hw) EG:BACR42I17.11 - CG18476 EG:BACR42I17.11 - D19A EG:BACR42I17.11 - CG10543 CG9609 - CG18476 CG9609 - CG10147 CG9609 - su(Hw) CG9609 - D19A CG9609 - CG2678 CG9609 - l(2)35Ea CG9609 - CG11696 CG9609 - rgr CG9609 - CG8301 CG9609 - CG7386 CG9609 - DIP:17897N CG9609 - CG10309 CG9609 - Phol CG9609 - CG10543 CG9609 - CG3941 CG9609 - D19B CG9609 - CG10654 CG9609 - CG7101 CG9609 - CG10979 EG:95B7.7 - CG4936 EG:95B7.7 - CG7928 EG:95B7.7 - CG7204 EG:95B7.7 - l(2)35Ea EG:95B7.7 - CG18764 EG:95B7.7 - CG4730 EG:95B7.7 - CG7386 EG:95B7.7 - CG8319 EG:95B7.7 - DIP:17332N EG:95B7.7 - CG8301 EG:95B7.7 - CG4820 EG:95B7.7 - GI:24653568 EG:95B7.7 - D19A DIP:20799N - CG8159 CG2889 - CG10267 CG2889 - odd CG2889 - CG8159 CkIIalpha-i1 - CG2120 CkIIalpha-i1 - CG1647 CkIIalpha-i1 - CG11696 CkIIalpha-i1 - CG15710 CkIIalpha-i1 - CG8301 CkIIalpha-i1 - D19A CG2202 - CG8301 CG2202 - CG12391 CG2202 - crol CG2202 - DIP:21597N l(2)35Ea - l(2)35Ea l(2)35Ea - CG7386 l(2)35Ea - CG8301 l(2)35Ea - CG10959 l(2)35Ea - D19A l(2)35Ea - CG17802 l(2)35Ea - CG7204 l(2)35Ea - CG4936 l(2)35Ea - EG:95B7.7 l(2)35Ea - CG18764 l(2)35Ea - CG14711 l(2)35Ea - sug l(2)35Ea - DIP:17378N l(2)35Ea - CG7928 l(2)35Ea - CG3281 l(2)35Ea - CG9797 l(2)35Ea - CG17568 l(2)35Ea - CG11696 l(2)35Ea - CG10267 l(2)35Ea - CG10274 l(2)35Ea - DIP:17897N l(2)35Ea - CG10654 l(2)35Ea - DIP:17332N l(2)35Ea - GI:24653568 l(2)35Ea - CG9609 l(2)35Ea - rgr l(2)35Ea - CG10147 l(2)35Ea - CG10309 l(2)35Ea - CG18476 l(2)35Ea - Phol l(2)35Ea - CG10543 l(2)35Ea - CG3941 l(2)35Ea - D19B l(2)35Ea - CG8319 l(2)35Ea - odd l(2)35Ea - CG7357 l(2)35Ea - CG4730 l(2)35Ea - CG4820 l(2)35Ea - CG11247 l(2)35Ea - CG10979 l(2)35Ea - CG17801 CG31365 - CG7386 CG31365 - CG9797 CG10321 - CG17385 CG10321 - CG17802 CG10321 - CG10267 CG11695 - odd CG11695 - CG11696 CG11695 - su(Hw) CG11695 - sug CG11695 - CG7386 CG11695 - CG7928 CG11695 - CTCF jing - CG7752 CG2678 - CG2678 CG2678 - CG9797 CG2678 - CG16779 CG2678 - CG7386 CG2678 - CG9609 CG2678 - CG10543 CG2678 - CG10462 CG2678 - CG7752 CG2678 - CG4820 CG2678 - CG7357 CG2678 - Aef1 CG18011 - CG7386 CG18011 - CG15073 CG18011 - CG4820 CG18011 - CG17802 CG18011 - CG3281 CG18011 - CG7357 CG18011 - DIP:17378N CG18011 - CG17801 CG18011 - CG10959 CG18011 - CG8159 CG12391 - CG10631 CG12391 - CG8301 CG12391 - CG2202 CG12391 - crol CG12391 - DIP:21597N DIP:21597N - CG8301 DIP:21597N - CG12391 DIP:21597N - CG2202 DIP:21597N - crol DIP:21597N - CG8319 DIP:21597N - CG7386 DIP:21597N - CG7987 DIP:21597N - DIP:17897N DIP:21597N - CG4820 DIP:21597N - DIP:121N CG9797 - CG1792 CG9797 - CG7357 CG9797 - CG7386 CG9797 - CG8301 CG9797 - DIP:17897N CG9797 - CG31782 CG9797 - D19A CG9797 - CG10654 CG9797 - wdn CG9797 - CG18764 CG9797 - CG6808 CG9797 - CG7928 CG9797 - DIP:17378N CG9797 - CG2116 CG9797 - CG10267 CG9797 - opa CG9797 - CG2678 CG9797 - CG3281 CG9797 - l(2)35Ea CG9797 - CG17568 CG9797 - CG11696 CG9797 - CG10959 CG9797 - CG17802 CG9797 - CG7204 CG9797 - CG10274 CG9797 - CG4730 CG9797 - CG17801 CG9797 - CG18555 CG9797 - DIP:22012N CG9797 - CG6254 CG9797 - odd CG9797 - CG4820 CG9797 - CG31365 CG9797 - CG7987 CG13620 - CG10979 CG13620 - GI:24645129 sug - CTCF sug - CG18476 sug - CG4496 sug - l(2)35Ea sug - CG7368 sug - CG17568 sug - CG7987 sug - CG10274 sug - CG11695 sug - CG10348 sug - GI:17647565 rgr - l(2)35Ea rgr - CG9609 rgr - CG11696 rgr - CG10147 rgr - CG8301 rgr - CG7386 rgr - DIP:17897N rgr - CG10309 rgr - CG18476 rgr - Phol rgr - CG10543 rgr - CG3941 rgr - D19B rgr - CG10654 CG11902 - CG11696 DIP:22012N - CG6254 DIP:22012N - CG17801 DIP:22012N - CG9797 DIP:22012N - DIP:17378N DIP:22012N - CG17802 CG8301 - CG7928 CG8301 - DIP:17897N CG8301 - CG9797 CG8301 - l(2)35Ea CG8301 - CG10654 CG8301 - CG7386 CG8301 - CG17568 CG8301 - CkIIalpha-i1 CG8301 - D19A CG8301 - CG8319 CG8301 - DIP:17332N CG8301 - EG:95B7.7 CG8301 - CG4820 CG8301 - GI:24653568 CG8301 - CG4730 CG8301 - CG17801 CG8301 - CG10959 CG8301 - CG7101 CG8301 - CG2120 CG8301 - CG7752 CG8301 - opa CG8301 - CG1792 CG8301 - CG7357 CG8301 - CG31782 CG8301 - CG17802 CG8301 - CG7204 CG8301 - CG9609 CG8301 - CG11696 CG8301 - rgr CG8301 - CG10147 CG8301 - CG10309 CG8301 - CG18476 CG8301 - Phol CG8301 - CG10543 CG8301 - CG3941 CG8301 - D19B CG8301 - CG4360 CG8301 - CG4854 CG8301 - CG8388 CG8301 - CG3032 CG8301 - CG18764 CG8301 - drm CG8301 - CG10267 CG8301 - Aef1 CG8301 - CG10274 CG8301 - CG8145 CG8301 - odd CG8301 - CG7963 CG8301 - CG2116 CG8301 - CG12391 CG8301 - CG2202 CG8301 - crol CG8301 - DIP:21597N CG8301 - CG12942 CG8301 - CG8159 CG8301 - DIP:17378N CG8301 - CG2052 CG8301 - DIP:18586N CG4854 - CG4360 CG4854 - wdn CG4854 - CG17806 CG4854 - CG17568 CG4854 - CG8388 CG4854 - CG7386 CG4854 - CG8301 CG4854 - CG3032 CG4854 - CG18764 CG4854 - D19A CG4854 - drm CG4854 - CG10267 CG4854 - Aef1 CG4854 - CG10274 CG4936 - CG4730 CG4936 - EG:95B7.7 CG4936 - DIP:17897N CG4936 - CG17801 CG4936 - CG6689 CG4936 - CG10654 CG4936 - l(2)35Ea CG4936 - CG18764 CG4936 - CG7928 CG4936 - DIP:17378N CG4936 - CTCF CG4936 - CG7204 CG4936 - EG:BACR42I17.11 CG4936 - Sry-delta CG4936 - CG10147 CG4936 - CG11798 CG4936 - CG10309 CG4936 - su(Hw) CG4936 - CG18476 CG4936 - D19A CG4936 - CG10543 Sry-beta - CG8159 Sry-beta - CG6808 Sry-beta - CG3281 Sry-beta - CG7928 Sry-beta - CG2116 Sry-beta - CG17568 Sry-beta - CG18764 Sry-beta - CG10274 Sry-delta - EG:BACR42I17.11 Sry-delta - CG10147 Sry-delta - CG11798 Sry-delta - CG4936 Sry-delta - CG10309 Sry-delta - su(Hw) Sry-delta - CG18476 Sry-delta - D19A Sry-delta - CG10543 DIP:22634N - CG9650 DIP:22690N - CG17568 DIP:22690N - CG7386 DIP:22690N - CG8159 DIP:22690N - EP2237 CG1647 - CG7386 CG1647 - CG17801 CG1647 - CkIIalpha-i1 CG1647 - CG11696 CG1647 - CG15710 CG1647 - CG8159 CG18555 - CG9797 hkb - CG1792 hkb - DIP:19658N hkb - odd hkb - D19A hkb - opa hkb - CG7386 CTCF - CG17568 CTCF - sug CTCF - CG18476 CTCF - CG4496 CTCF - CG11798 CTCF - CG10543 CTCF - CG4936 CTCF - CG7928 CTCF - DIP:17378N CTCF - CG7386 CTCF - CG11695 CG7101 - drm CG7101 - CG8301 CG7101 - CG2120 CG7101 - CG9609 CG7101 - CG10979 CG3281 - CG7386 CG3281 - CG8159 CG3281 - DIP:17378N CG3281 - CG7928 CG3281 - CG9797 CG3281 - l(2)35Ea CG3281 - CG17568 CG3281 - CG11696 CG3281 - CG10959 CG3281 - CG18764 CG3281 - D19A CG3281 - CG17802 CG3281 - CG10267 CG3281 - CG7204 CG3281 - CG10274 CG3281 - CG7357 CG3281 - CG18011 CG3281 - CG17801 CG3281 - Sry-beta CG3281 - CG2116 CG4730 - DIP:17897N CG4730 - CG4936 CG4730 - CG17801 CG4730 - CG6689 CG4730 - CG10654 CG4730 - CG8301 CG4730 - CG9797 CG4730 - CG10959 CG4730 - EG:95B7.7 CG4730 - CG32767 CG4730 - CG10979 CG4730 - CG12942 CG4730 - CG7386 CG4730 - CG8159 CG4730 - CG7357 CG4730 - l(2)35Ea CG4730 - CG4820 DIP:23106N - CG8159 DIP:23106N - CG9793 CG7928 - CG7386 CG7928 - CG8319 CG7928 - DIP:17332N CG7928 - CG8301 CG7928 - EG:95B7.7 CG7928 - CG4820 CG7928 - GI:24653568 CG7928 - CG9793 CG7928 - DIP:17378N CG7928 - CG3281 CG7928 - CG9797 CG7928 - l(2)35Ea CG7928 - CG17568 CG7928 - CG11696 CG7928 - CG10959 CG7928 - CG18764 CG7928 - D19A CG7928 - CG17802 CG7928 - CG10267 CG7928 - CG7204 CG7928 - CG10274 CG7928 - CG15073 CG7928 - opa CG7928 - CG2116 CG7928 - CG6808 CG7928 - DIP:17897N CG7928 - CG10654 CG7928 - Sry-beta CG7928 - CG4936 CG7928 - CTCF CG7928 - CG11695 CG7928 - CG7987 CG12701 - CG7386 CG12701 - DIP:19658N CG7386 - CG7386 CG7386 - DIP:17378N CG7386 - CG7928 CG7386 - CG3281 CG7386 - CG9797 CG7386 - l(2)35Ea CG7386 - CG17568 CG7386 - CG11696 CG7386 - CG10959 CG7386 - CG18764 CG7386 - D19A CG7386 - CG17802 CG7386 - CG10267 CG7386 - CG7204 CG7386 - CG10274 CG7386 - CG7987 CG7386 - bowl CG7386 - odd CG7386 - CG18011 CG7386 - CG15073 CG7386 - CG4820 CG7386 - CG2678 CG7386 - CG31365 CG7386 - CG10462 CG7386 - CG8301 CG7386 - DIP:17897N CG7386 - CG12701 CG7386 - CG8319 CG7386 - DIP:21597N CG7386 - DIP:121N CG7386 - DIP:17332N CG7386 - EG:95B7.7 CG7386 - GI:24653568 CG7386 - CG8159 CG7386 - CG10654 CG7386 - CG1647 CG7386 - CG17801 CG7386 - CG1792 CG7386 - CG7357 CG7386 - CG31782 CG7386 - hkb CG7386 - DIP:19658N CG7386 - DIP:22690N CG7386 - EP2237 CG7386 - CG9609 CG7386 - rgr CG7386 - CG10147 CG7386 - CG10309 CG7386 - CG18476 CG7386 - Phol CG7386 - CG10543 CG7386 - CG3941 CG7386 - D19B CG7386 - CG4360 CG7386 - CG4854 CG7386 - CG8388 CG7386 - CG3032 CG7386 - drm CG7386 - Aef1 CG7386 - CG11247 CG7386 - CG4730 CG7386 - CG12942 CG7386 - CG9793 CG7386 - CG17612 CG7386 - CG11695 CG7386 - CTCF CG7386 - crol CG7357 - CG9797 CG7357 - CG2116 CG7357 - CG14711 CG7357 - CG3281 CG7357 - DIP:17378N CG7357 - CG18011 CG7357 - CG17801 CG7357 - CG10959 CG7357 - CG8159 CG7357 - CG1792 CG7357 - CG7386 CG7357 - CG8301 CG7357 - DIP:17897N CG7357 - CG31782 CG7357 - D19A CG7357 - CG10654 CG7357 - CG8145 CG7357 - CG17612 CG7357 - CG4730 CG7357 - l(2)35Ea CG7357 - CG4820 CG7357 - CG10147 CG7357 - CG2678 CG7357 - Aef1 CG10147 - CG9609 CG10147 - su(Hw) CG10147 - D19A CG10147 - CG11971 CG10147 - l(2)35Ea CG10147 - CG11696 CG10147 - rgr CG10147 - CG8301 CG10147 - CG7386 CG10147 - DIP:17897N CG10147 - CG10309 CG10147 - CG18476 CG10147 - Phol CG10147 - CG10543 CG10147 - CG3941 CG10147 - D19B CG10147 - CG10654 CG10147 - EG:BACR42I17.11 CG10147 - Sry-delta CG10147 - CG11798 CG10147 - CG4936 CG10147 - CG18764 CG10147 - CG7357 CG1832 - CG7987 CG1832 - CG18262 CG1832 - crol CG1832 - CG10543 CG1832 - CG11971 CG1832 - D19B CG17806 - CG4854 zfh1 - DIP:18586N zfh1 - CG2052 zfh1 - odd zfh1 - CG8145 CG7963 - CG1792 CG7963 - CG8301 CG7963 - CG2116 CG7963 - CG10267 CG8145 - CG10348 CG8145 - CG7357 CG8145 - zfh1 CG8145 - CG8301 CG8145 - CG17801 CG8145 - opa CG1792 - CG1792 CG1792 - CG9797 CG1792 - CG18764 CG1792 - CG8159 CG1792 - DIP:19658N CG1792 - hkb CG1792 - odd CG1792 - opa CG1792 - CG7357 CG1792 - CG7386 CG1792 - CG8301 CG1792 - DIP:17897N CG1792 - CG31782 CG1792 - D19A CG1792 - CG10654 CG1792 - CG7963 CG1792 - CG2116 CG1792 - CG10267 CG1792 - CG9793 CG8319 - CG7928 CG8319 - CG15073 CG8319 - CG17802 CG8319 - opa CG8319 - CG7386 CG8319 - CG7987 CG8319 - DIP:21597N CG8319 - DIP:17897N CG8319 - CG4820 CG8319 - DIP:121N CG8319 - DIP:17332N CG8319 - CG8301 CG8319 - EG:95B7.7 CG8319 - GI:24653568 CG8319 - l(2)35Ea CG8319 - CG11247 CG8319 - crol CG8319 - CG10654 CG8319 - CG10979 CG11798 - CG2116 CG11798 - CG7987 CG11798 - CTCF CG11798 - CG10543 CG11798 - EG:BACR42I17.11 CG11798 - Sry-delta CG11798 - CG10147 CG11798 - CG4936 CG11798 - CG10309 CG11798 - su(Hw) CG11798 - CG18476 CG11798 - D19A CG11798 - CG17568 CG11798 - CG40145 CG14962 - CG7987 CG14962 - CG33213 CG8388 - CG17568 CG8388 - CG4360 CG8388 - CG4854 CG8388 - CG7386 CG8388 - CG8301 CG8388 - CG3032 CG8388 - CG18764 CG8388 - D19A CG8388 - drm CG8388 - CG10267 CG8388 - Aef1 CG8388 - CG10274 CG8388 - DIP:18586N CG8388 - CG2052
KOG1048 - KOG1721	Catns - Zfp145	PKP2 - E4F1 PKP2 - ZF6 PKP2 - SIP1 PKP2 - ZNF83 PKP2 - FLJ20765	p120ctn - CG10147
KOG0594 - KOG1721	CDK4 - ZAC1	CDC2 - KLF6 CDC2 - Sp1 CDC2 - YY1 CDK4 - OSR1 CDK4 - KLF6 CDK4 - PLAG1 CDK4 - HIVEP1 CDK4 - SIP1 CDK4 - ZNF83 CDK4 - FLJ12586 CDK4 - PLAGL1 CDK4 - PRDM4 CDK4 - PLZF CDK4 - Sp1 CDK6 - OSR1 CDK6 - KLF6 CDK2 - KLF6 CDK2 - PLAG1 CDK2 - HIVEP1 CDK2 - SIP1 CDK2 - ZNF83 CDK2 - FLJ12586 CDK2 - PLAGL1 CDK2 - PRDM4 CDK2 - PLZF CDK2 - Sp1 PFTK1 - OSR1	CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543 cdc2 - sug
KOG1500 - KOG1721	CARM1 - ZAC1	CARM1 - Egr1 CARM1 - YY1	CG5358 - CG1792 CG5358 - DIP:19658N CG5358 - hkb CG5358 - odd CG5358 - DIP:17378N CG5358 - D19A CG6563 - CG11798
KOG0736 - KOG2330	Pex6 - SF3b2	Pex6 - SF3b2	DIP:18011N - CG3605
KOG1721 - KOG3575	ZAC1 - DIP:125N ZAC1 - GI:6679695 ZAC1 - GI:7304901 BCL-6 - PPAR-delta	DIP:36N - VDR FLJ20765 - PPARD YY1 - ER-alpha YY1 - DIP:1044N YY1 - VDR Miz-1 - ER-alpha Miz-1 - ER-beta Miz-1 - DIP:622N PLZF - ER-alpha PLZF - PPARD PLZF - VDR PLZF - ER-beta PLZF - RAR ZNF83 - PPARD ZNF83 - VDR zid - PPARD zid - ER-alpha CTCF - RXR-beta PRDM4 - VDR FLJ12586 - VDR SIP1 - PPARD SIP1 - VDR SIP1 - RARB SIP1 - RXR-alpha Egr1 - ER-beta Egr1 - RAR Egr1 - ER-alpha DIP:5990N - ER-alpha DIP:5990N - DIP:622N DIP:5990N - ER-beta DIP:5990N - DIP:5999N DIP:5990N - RXR-beta ZF6 - PPARD ZFD25 - NR2F2 HIVEP1 - VDR E4F1 - PPARD BCL6 - PPARD BCL6 - ER-alpha PLAGL1 - VDR Sp1 - ER-beta Sp1 - RAR Sp1 - ER-alpha Sp1 - RXR-alpha PLAG1 - VDR	opa - Hr39 opa - DIP:18899N opa - ftz-f1 CG10274 - ftz-f1 CG10274 - DIP:18899N CG7752 - ftz-f1 D19A - svp D19A - tll su(Hw) - svp CG7987 - DIP:18899N CG7987 - ftz-f1 CG17801 - Hr96 GI:17647565 - tll DIP:19928N - DIP:18899N CG10348 - ftz-f1 CG10348 - Hr96 CG10348 - DIP:18899N CG10348 - tll CG17568 - DIP:18899N CG17568 - ftz-f1 CG9609 - svp l(2)35Ea - DIP:18899N l(2)35Ea - ftz-f1 jing - ftz-f1 sug - DIP:18899N sug - tll sug - ftz-f1 CG1647 - Hr96 CG4730 - ftz-f1 CG4730 - DIP:18899N CG7386 - Hr96 CG10147 - svp CG8145 - Hr96 CG8145 - Hr39 CG11762 - Hr39
KOG0594 - KOG3575	CDK4 - GI:6679695 CDK4 - GI:7304901	CDC2 - ER-alpha CDC2 - DIP:1044N CDK4 - VDR CDK4 - ER-alpha CDK4 - RARB CDK4 - RXR-alpha CDK4 - GI:21322252 CDK6 - VDR CDK6 - RAR CDK6 - GI:21322252 CDK2 - VDR CDK2 - ER-alpha CDK2 - RARB CDK2 - RXR-alpha CDK2 - GI:21322252	CG30171 - ftz-f1
KOG3575 - KOG3575	RXRA - RXRA GI:7304901 - GI:6679695 GI:6679695 - GI:7304901 Esrrg - Esrrg	DIP:158N - RXR-alpha DIP:158N - VDR DIP:158N - NR1H4 DIP:158N - PPAR-alpha DIP:158N - RAR DIP:158N - PPARG PPAR-gamma-2 - LXR-alpha PPAR-gamma-2 - ER-alpha PPAR-gamma-2 - GI:21322252 PPAR-gamma-2 - ER-beta PPAR-gamma-2 - PPAR-alpha PPAR-gamma-2 - PPARG PPARG - RXR-alpha PPARG - PPARG PPARG - VDR PPARG - NR1H4 PPARG - DIP:158N PPARG - PPAR-alpha PPARG - RAR PPARG - ER-alpha PPARG - GI:21322252 PPARG - ER-beta PPARG - PPAR-gamma-2 RAR - RXR-alpha RAR - PPAR-alpha RAR - VDR RAR - ER-alpha RAR - GI:21322252 RAR - NR1H4 RAR - DIP:158N RAR - PPARG RAR - ER-beta DIP:622N - ER-alpha DIP:622N - ER-beta RXR-alpha - VDR RXR-alpha - RXR-alpha RXR-alpha - NR1H4 RXR-alpha - DIP:158N RXR-alpha - PPAR-alpha RXR-alpha - RAR RXR-alpha - PPARG RXR-alpha - ER-alpha RXR-alpha - GI:21322252 RXR-alpha - RARB RXR-alpha - ER-beta DIP:1044N - ER-alpha RARB - RXR-alpha ER-beta - ER-alpha ER-beta - DIP:622N ER-beta - RAR ER-beta - GI:21322252 ER-beta - PPAR-alpha ER-beta - PPARG ER-beta - PPAR-gamma-2 ER-beta - RXR-alpha VDR - VDR VDR - RXR-alpha VDR - RAR VDR - ER-alpha VDR - GI:21322252 VDR - NR1H4 VDR - DIP:158N VDR - PPAR-alpha VDR - PPARG PPAR-alpha - PPAR-alpha PPAR-alpha - RXR-alpha PPAR-alpha - RAR PPAR-alpha - ER-alpha PPAR-alpha - GI:21322252 PPAR-alpha - ER-beta PPAR-alpha - PPARG PPAR-alpha - PPAR-gamma-2 PPAR-alpha - VDR PPAR-alpha - NR1H4 PPAR-alpha - DIP:158N LXR-alpha - PPAR-gamma-2 RXR-beta - RXR-beta RXR-beta - ER-alpha CAR - ER-alpha GI:21322252 - ER-alpha GI:21322252 - VDR GI:21322252 - RXR-alpha GI:21322252 - RAR GI:21322252 - ER-beta GI:21322252 - PPAR-alpha GI:21322252 - PPARG GI:21322252 - PPAR-gamma-2 NR1H4 - RXR-alpha NR1H4 - VDR NR1H4 - DIP:158N NR1H4 - PPAR-alpha NR1H4 - RAR NR1H4 - PPARG ER-alpha - ER-alpha ER-alpha - DIP:622N ER-alpha - ER-beta ER-alpha - RAR ER-alpha - RXR-beta ER-alpha - LRH-1 ER-alpha - GI:21322252 ER-alpha - VDR ER-alpha - RXR-alpha ER-alpha - CAR ER-alpha - DIP:1044N ER-alpha - PPAR-alpha ER-alpha - PPARG ER-alpha - PPAR-gamma-2 PPARD - PPARD LRH-1 - ER-alpha	DIP:18899N - ftz-f1 Hr39 - tll ftz-f1 - DIP:18899N tll - Hr39 USP - USP
KOG3575 - KOG3960	VDR - MyoD	RAR - MYOG RAR - MyoD ER-alpha - MyoD	ftz-f1 - nau
KOG1500 - KOG3575	CARM1 - GI:6679695 CARM1 - GI:7304901	CARM1 - ER-alpha CARM1 - DIP:1044N	CG5358 - tll
KOG2330 - KOG3575	SF3b2 - VDR	SF3b2 - VDR	CG3605 - tll
KOG2294 - KOG3575	Foxh1 - VDR Foxo1 - LXR-alpha	FoxO4 - VDR FoxH1 - VDR FoxH1 - RARB FoxH1 - RXR-alpha FoxO3 - VDR FoxO1 - VDR	fd59A - Hr39 fd64A - tll
KOG3575 - HG10522	VDR - 4-ET	VDR - 4-ET	DIP:18899N - CG32016 DIP:18899N - Cup Hr39 - Cup ftz-f1 - CG32016 ftz-f1 - Cup tll - CG32016
KOG2330 - HG10522	SF3b2 - 4-ET	SF3b2 - 4-ET	CG3605 - CG32016
KOG3701 - HG10522	Smad1 - 4-ET Smad3 - 4-ET Smad4 - 4-ET Smad7 - 4-ET Smad2 - 4-ET	Smad1 - 4-ET Smad2 - 4-ET Smad3 - 4-ET SMAD4 - 4-ET	Smox - CG32016
KOG2294 - HG10522	Foxh1 - 4-ET	FoxO4 - 4-ET FoxH1 - 4-ET FoxO3 - 4-ET FoxO1 - 4-ET	fd59A - CG32016
KOG0940 - HG10522	Itch - 4-ET	SMURF2 - 4-ET SMURF1 - 4-ET SMURF1 - 4-ET	CG3099 - Cup
KOG0940 - KOG2294	Itch - Foxh1	FLJ32109 - FoxH1 SMURF2 - FoxO3 SMURF2 - FoxH1 SMURF2 - FoxO1 SMURF2 - FoxO4 SMURF1 - FoxO3 SMURF1 - FoxH1 SMURF1 - FoxO1 SMURF1 - FoxO4 SMURF1 - FoxO3 SMURF1 - FoxH1 SMURF1 - FoxO1 SMURF1 - FoxO4	CG7552 - fd59A CG3099 - fd64A
KOG0940 - KOG3701	Itch - Smad2	NEDD4 - Smad5 NEDD4 - Smad1 NEDD4 - SMAD4 NEDD4 - Smad3 KIAA1301 - Smad1 KIAA1301 - SMAD4 KIAA1301 - Smad5 KIAA1301 - Smad3 AIP5 - Smad5 AIP5 - SMAD4 AIP5 - Smad1 FLJ32109 - Smad2 FLJ32109 - SMAD4 FLJ32109 - Smad3 FLJ32109 - Smad8 SMURF2 - Smad5 SMURF2 - SMAD7 SMURF2 - Smad6 SMURF2 - Smad3 SMURF2 - Smad2 SMURF2 - Smad1 SMURF2 - SMAD4 SMURF2 - Smad8 SMURF2 - Smad8a SMURF1 - Smad6 SMURF1 - SMAD7 SMURF1 - Smad3 SMURF1 - Smad1 SMURF1 - SMAD4 SMURF1 - Smad2 SMURF1 - Smad8 SMURF1 - Smad5 SMURF1 - Smad5 SMURF1 - Smad3 SMURF1 - Smad2 SMURF1 - Smad1 SMURF1 - SMAD4 SMURF1 - Smad8	CG7552 - Smox CG7552 - Mad lack - Mad
KOG0940 - KOG4196	Itch - Mafb	NEDD4 - MafK NEDD4 - MafG hYAP - MafK hYAP - MafG	CG3099 - CG10034
KOG0578 - KOG0940	PAK1 - Itch	PAK - SMURF1 PAK - SMURF2 PAK - SMURF1 PAK - FLJ32109 PAK - KIAA1301 PAK - NEDD4	CG30171 - Nedd4
KOG0940 - KOG1703	Smurf1 - Cypher1	SMURF2 - ARA55 SMURF1 - CLP-36 SMURF1 - ARA55 SMURF1 - ARA55	CG7552 - CG32018 CG7552 - stck Nedd4 - stck
KOG0578 - KOG2052	PAK1 - TGF-beta R PAK1 - Acvrl1	PAK - TGF-beta-R-I PAK - BMPR1B PAK - ACVR1 PAK - ALK1	CG30171 - babo
KOG0940 - KOG2052	Itch - TGF-beta R Itch - Acvrl1 Smurf1 - TGF-beta R	FLJ32109 - TGF-beta-R-I SMURF2 - TGF-beta-R-I SMURF2 - BMPR1B SMURF2 - ACVR1 SMURF1 - TGF-beta-R-I SMURF1 - BMPR1B SMURF1 - ACVR1 SMURF1 - TGF-beta-R-I	Nedd4 - babo
KOG2052 - KOG3653	ACVR1 - Acvr2b BMPR1B - DIP:5794N BMPR1B - Acvr2 BMPR1B - Acvr2b DIP:5793N - DIP:5794N DIP:5793N - Acvr2	DIP:427N - ACVR2 ALK1 - ACVR2 ACVR1 - ACVR2 BMPR1B - BMPR2 TGF-beta-R-I - ACVR2	babo - put
KOG1703 - KOG2052	Paxillin - TGF-beta R	CLP-36 - TGF-beta-R-I CLP-36 - BMPR1B ARA55 - TGF-beta-R-I	stck - babo
KOG1214 - KOG1215	DIP:5N - DIP:214N DIP:214N - DIP:5N Nidogen-1 - Perlecan	DIP:5762N - EGF NID - LRP1 NID2 - LRP1	DIP:17770N - DIP:18444N DIP:17770N - DIP:17306N sli - CG12139 sli - trol
KOG1218 - KOG1219	DIP:214N - DIP:5N DLK1 - DIP:6008N	FLJ90754 - PCDH1	CG12908 - GI:17352473 trol - sli GI:24584298 - GI:17352473
KOG1217 - KOG1218	DIP:5N - DIP:214N Fibulin-2 - Perlecan DLK1 - DLK1 DIP:6008N - DLK1	FLJ14964 - FLJ90754 FLJ14964 - DKK1 DKFZP761E1824 - FLJ90754 fibulin-1A - FLJ90754	DIP:24016N - CG7526 CG12908 - GI:24584298 SP1070 - trol DIP:17770N - BG:DS00180.10 DIP:17770N - BG:DS00180.8 DIP:17770N - BG:DS00180.14 CG7447 - BG:DS00180.10 CG7447 - BG:DS00180.8 DIP:18444N - BG:DS00180.10 BG:DS00180.8 - BG:DS00180.10 BG:DS00180.8 - BG:DS00180.14 CG31999 - BG:DS00180.10 CG31999 - BG:DS00180.8 CG31999 - BG:DS00180.14 trol - sli GI:24584298 - CG12908 GI:24648166 - BG:DS00180.10 BG:DS00180.10 - BG:DS00180.8 BG:DS00180.10 - BG:DS00180.14 C901 - BG:DS00180.10 C901 - BG:DS00180.8 C901 - BG:DS00180.14 CG5639 - trol CG9572 - BG:DS00180.10 CG9572 - trol CG9572 - BG:DS00180.8 CG9572 - BG:DS00180.14 sli - trol
KOG1215 - KOG1217	DIP:5N - DIP:214N DIP:214N - DIP:5N Perlecan - Fibulin-2 DIP:6008N - DLK1	LRP1 - fibulin-1A LRP1 - FLJ14964 LRP1 - FLJ90754 EGF - DIP:5762N LRP5 - FLJ14964	CG7526 - DIP:24016N CG12908 - GI:24584298 DIP:17306N - DIP:17770N DIP:18444N - BG:DS00180.10 DIP:18444N - DIP:17770N DIP:18444N - CG9572 DIP:18444N - C901 trol - sli trol - CG9572 trol - CG5639 trol - SP1070 CG12139 - trol CG12139 - sli CG8909 - trol CG8909 - CG9572
KOG1214 - KOG1217	DIP:5N - DIP:214N DIP:214N - DIP:5N DIP:6008N - DLK1 Nidogen-1 - Fibulin-2 Nidogen-1 - Perlecan	NID - fibulin-1A NID - FLJ14964 NID - FLJ90754 NID2 - fibulin-1A NID2 - FLJ14964 NID2 - FLJ90754	CG7526 - DIP:24016N CG12908 - GI:24584298 DIP:17770N - CG7447 DIP:17770N - DIP:18444N DIP:17770N - CG9572 DIP:17770N - C901 DIP:17770N - BG:DS00180.10 DIP:17770N - CG31999 DIP:17770N - BG:DS00180.8 DIP:17770N - DIP:17306N sli - trol
KOG1217 - KOG3209	Delta1 - MAGI-1	Delta1 - MAGI-1	CG31999 - GI:24657721 GI:24648166 - GI:24657721 BG:DS00180.10 - GI:24657721 Crb - Dlt
KOG1217 - HG8189	Delta1 - MAGI-2	KIAA0816 - KIAA1526	CG12908 - Nedd4 BG:DS00180.8 - DIP:18367N CG31999 - DIP:18367N CG31999 - GI:24657721 CG31999 - scrib GI:24648166 - GI:24657721 GI:24648166 - scrib BG:DS00180.10 - GI:24657721 Crb - Dlt CG9572 - DIP:18367N
KOG1217 - KOG3509	DIP:5N - DIP:214N DIP:214N - DIP:5N DLK1 - DIP:6008N	FLJ90754 - HSPG2 LTBP3 - HSPG2 DKFZP761E1824 - HSPG2	CG12908 - GI:24584298 SP1070 - trol SP1070 - Robo SP1070 - Ppn DIP:17770N - sls DIP:17770N - DIP:17668N CG7447 - DIP:17668N CG7447 - Ppn CG31999 - DIP:17668N CG31999 - Ppn trol - Ppn trol - Robo BG:DS00180.10 - DIP:17668N BG:DS00180.10 - Ppn C901 - DIP:17668N C901 - Ppn CG5639 - trol CG5639 - Robo CG5639 - Ppn CG9572 - trol CG9572 - Robo CG9572 - Ppn sli - trol
KOG1217 - KOG1219	DIP:5N - DIP:214N DIP:214N - DIP:5N DLK1 - DIP:6008N	FLJ90754 - PCDH1 DKFZP761E1824 - PCDH1	CG12908 - GI:17352473 trol - sli GI:24584298 - GI:17352473
KOG1217 - KOG1217	DIP:5N - DIP:214N DIP:214N - DIP:5N Perlecan - Fibulin-2 Fibulin-2 - Perlecan Fbn1 - Fbn2 Fbn1 - Delta1 DLK1 - DLK1 DLK1 - DIP:6008N DIP:6008N - DLK1 Delta1 - Fbn2 Delta1 - Fbn1 Fbn2 - Delta1 Fbn2 - Fbn1	Fibrillin-1 - Fibulin-2 Fibrillin-1 - FBN2 FLJ90754 - fibulin-1A FLJ90754 - FLJ14964 FLJ90754 - DKFZP761E1824 FLJ14964 - fibulin-1A FLJ14964 - FLJ90754 Fibulin-2 - Fibrillin-1 Fibulin-2 - FBN2 FBN2 - Fibrillin-1 FBN2 - Fibulin-2 DKFZP761E1824 - FLJ90754 fibulin-1A - FLJ14964 fibulin-1A - FLJ90754	DIP:24016N - CG7526 CG7526 - DIP:24016N CG12908 - GI:24584298 DIP:17306N - DIP:17770N SP1070 - CG9572 SP1070 - CG5639 SP1070 - trol DIP:17770N - CG7447 DIP:17770N - DIP:18444N DIP:17770N - CG9572 DIP:17770N - C901 DIP:17770N - BG:DS00180.10 DIP:17770N - CG31999 DIP:17770N - BG:DS00180.8 DIP:17770N - DIP:17306N CG7447 - DIP:17770N CG7447 - CG9572 CG7447 - BG:DS00180.10 CG7447 - BG:DS00180.8 CG7447 - C901 CG7447 - CG31999 DIP:18444N - BG:DS00180.10 DIP:18444N - DIP:17770N DIP:18444N - CG9572 DIP:18444N - C901 BG:DS00180.8 - DIP:17770N BG:DS00180.8 - CG7447 BG:DS00180.8 - BG:DS00180.10 BG:DS00180.8 - C901 BG:DS00180.8 - CG9572 BG:DS00180.8 - CG31999 CG31999 - CG9572 CG31999 - DIP:17770N CG31999 - BG:DS00180.10 CG31999 - C901 CG31999 - BG:DS00180.8 CG31999 - CG7447 trol - sli trol - CG9572 trol - CG5639 trol - SP1070 GI:24584298 - CG12908 GI:24648166 - BG:DS00180.10 GI:24648166 - CG9572 BG:DS00180.10 - DIP:17770N BG:DS00180.10 - DIP:18444N BG:DS00180.10 - CG9572 BG:DS00180.10 - C901 BG:DS00180.10 - CG31999 BG:DS00180.10 - CG7447 BG:DS00180.10 - GI:24648166 BG:DS00180.10 - BG:DS00180.8 C901 - DIP:17770N C901 - DIP:18444N C901 - CG9572 C901 - BG:DS00180.10 C901 - CG31999 C901 - CG7447 C901 - BG:DS00180.8 CG5639 - CG9572 CG5639 - trol CG5639 - SP1070 CG9572 - BG:DS00180.10 CG9572 - DIP:17770N CG9572 - DIP:18444N CG9572 - C901 CG9572 - CG31999 CG9572 - CG7447 CG9572 - GI:24648166 CG9572 - CG5639 CG9572 - trol CG9572 - SP1070 CG9572 - BG:DS00180.8 sli - trol
KOG1217 - KOG1836	DIP:5N - DIP:214N DIP:214N - DIP:5N Fibulin-2 - Lamc1 Fibulin-2 - Perlecan DLK1 - DIP:6008N	FLJ90754 - LAMA4 FLJ90754 - LAMC1 FLJ90754 - laminin 5 FBN2 - laminin 5 DKFZP761E1824 - LAMA4 DKFZP761E1824 - LAMC1 DKFZP761E1824 - laminin 5	CG12908 - GI:24584298 SP1070 - LanA SP1070 - LanB2 SP1070 - trol CG31999 - DIP:20672N trol - LanA trol - sli trol - LanB2 CG5639 - LanA CG5639 - LanB2 CG5639 - trol CG9572 - LanA CG9572 - LanB2 CG9572 - trol sli - trol
KOG1217 - KOG2052	Ltbp3 - TGF-beta R	FLJ90754 - TGF-beta-R-I FBN2 - TGF-beta-R-I fibulin-1A - TGF-beta-R-I	DIP:17306N - DIP:17304N trol - babo
KOG1217 - KOG3528	Delta1 - MUPP1	KIAA0816 - KIAA1526	DIP:17770N - X11L DIP:17770N - INAD DIP:17770N - CG14168 DIP:17770N - Patj DIP:18444N - CG6688 DIP:18444N - INAD BG:DS00180.8 - CG6619 BG:DS00180.8 - DIP:18367N CG31999 - DIP:18367N CG31999 - scrib trol - X11L GI:24584298 - CG6619 GI:24648166 - scrib BG:DS00180.10 - CG6619 BG:DS00180.10 - CG14168 BG:DS00180.10 - X11L Crb - Dlt Crb - Bazooka Crb - Patj CG9572 - DIP:18367N

---

Conserved subnet 4:
47 conserved interactions between 42 ortholog groups.
This subnet exists in 3 organisms (p<4e-56).

Ortholog Groups
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG2220	Predicted signal transduction protein
KOG2169	Zn-finger transcription factor
KOG2294	Transcription factor of the Forkhead/HNF3 family
KOG0653	Cyclin B and related kinase-activating proteins
KOG3484	Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins
KOG1279	Chromatin remodeling factor subunit and related transcription factors
KOG1649	SWI-SNF chromatin remodeling complex, Snf5 subunit
KOG0946	ER-Golgi vesicle-tethering protein p115
KOG3092	Casein kinase II, beta subunit
KOG1074	Transcriptional repressor SALM
KOG0668	Casein kinase II, alpha subunit
KOG0890	Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination
KOG1164	Casein kinase (serine/threonine/tyrosine protein kinase)
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0714	Molecular chaperone (DnaJ superfamily)
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG1721	FOG: Zn-finger
KOG1994	Predicted RNA binding protein, contains G-patch and Zn-finger domains
KOG2166	Cullins
KOG2330	Splicing factor 3b, subunit 2
KOG3565	Cdc42-interacting protein CIP4
KOG1844	PHD Zn-finger proteins
KOG2005	26S proteasome regulatory complex, subunit RPN1/PSMD2
KOG2151	Predicted transcriptional regulator
KOG3320	40S ribosomal protein S7
KOG3780	Thioredoxin binding protein TBP-2/VDUP1
KOG1973	Chromatin remodeling protein, contains PHD Zn-finger
KOG1342	Histone deacetylase complex, catalytic component RPD3
KOG1507	Nucleosome assembly protein NAP-1
KOG1704	FOG: LIM domain
KOG0864	Ran-binding protein RANBP1 and related RanBD domain proteins
KOG0694	Serine/threonine protein kinase
KOG0676	Actin and related proteins
KOG0749	Mitochondrial ADP/ATP carrier proteins
KOG0841	Multifunctional chaperone (14-3-3 family)
KOG0740	AAA+-type ATPase
KOG1290	Serine/threonine protein kinase
KOG1466	Translation initiation factor 2B, alpha subunit (eIF-2Balpha/GCN3)
KOG0660	Mitogen-activated protein kinase
KOG0960	Mitochondrial processing peptidase, beta subunit, and related enzymes (insulinase superfamily)
KOG0867	Glutathione S-transferase

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1703 - KOG2220	DIP:17600N - CG12876	C34B2.4 - R10E12.1	LRG - Vps31
KOG2169 - KOG2294	CG7958 - CG11799 DIP:18140N - CG11799	DIP:26255N - DAF-16	NFI1 - Fhl1
KOG0653 - KOG3484	DIP:17624N - CG9790 CycG - DIP:102N CycG - CG9790	DIP:24822N - C09G4.3 R02F2.1 - C09G4.3 H31G24.4 - C09G4.3	Clb3 - CKS1 Clb3 - DIP:102N Clb1 - CKS1 Clb1 - DIP:102N Clb6 - DIP:102N Clb6 - CKS1 Clb4 - CKS1 Clb4 - DIP:102N Cln1 - CKS1 Cln1 - DIP:102N Cln2 - CKS1 Cln2 - DIP:102N Clb2 - CKS1 Clb2 - DIP:102N Clb5 - CKS1 Clb5 - DIP:102N Cln3 - CKS1 Cln3 - DIP:102N
KOG1279 - KOG1649	mor - Snr1	Y113G7B.23 - R07E5.3	RSC8 - SFH1 RSC8 - Snf5 SWI3 - Snf5
KOG0946 - KOG3092	p115 - CKII-beta	K09B11.9 - T01G9.6 K09B11.9 - DIP:24683N C14H10.2 - T01G9.6 C14H10.2 - DIP:24683N DIP:25932N - T01G9.6 DIP:25932N - DIP:24683N	Uso1p - CKB1
KOG1074 - KOG3092	CG10274 - CKII-beta CG6254 - CKII-beta CG6808 - CKII-beta	F15C11.1 - T01G9.6 F15C11.1 - DIP:24683N	DIP:150N - CKB2
KOG0668 - KOG3092	CKII-alpha - CKII-beta	B0205.7 - T01G9.6	CKA1 - CKB2 CKA1 - CKB1 CKA2 - CKB2 CKA2 - CKB1
KOG0890 - KOG1164	mei-41 - dco	T06E4.3 - F46F2.2	Mec1 - Hrr25
KOG0581 - KOG0714	DIP:23499N - DnaJ-1	MEK-2 - F54D5.7	Mkk1 - Sis1p Mkk2 - Sis1p
KOG0581 - KOG0940	CG30171 - Nedd4	MEK-2 - F13E6.4	Mkk2 - Rsp5
KOG1721 - KOG3484	opa - CG9790 sug - DIP:102N sug - CG9790 Sqz - CG9790 zfh1 - CG9790	ZK892.7 - Y71G12B.27	Swi5 - DIP:102N Swi5 - CKS1 Ace2 - DIP:102N Ace2 - CKS1
KOG1721 - KOG1994	CG6808 - CG10053 CG17801 - CG10053 CG9797 - CG10053 CG7928 - CG10053 CG8145 - CG10053	C07A12.1 - T04H1.5	ADR1 - DIP:6448N
KOG1721 - KOG2166	CG10543 - lin19 D19A - lin19 CG18476 - lin19 su(Hw) - lin19 CG10309 - lin19 EG:BACR42I17.11 - lin19 CG4936 - lin19 Sry-delta - lin19 CG7386 - lin19 CG10147 - lin19 CG11798 - lin19	R08E3.4 - CUL-3 ZK892.7 - CUL-3	Nrg2 - RTT101 ADR1 - RTT101 ADR1 - CUL3 ADR1 - Cdc53 Ygr067c - RTT101 Met31 - Cdc53
KOG1721 - KOG2330	odd - CG3605 bowl - CG3605 CG8159 - CG3605 D19A - CG3605 CG2116 - CG3605 CG10462 - CG3605 CG2889 - CG3605	F53B3.1 - W03F9.10 C27A12.2 - W03F9.10 F57C9.4 - W03F9.10	Swi5 - Cus1 MIG1 - Cus1 Nrg1p - Cus1
KOG1721 - KOG3092	opa - CKII-beta CG10274 - CKII-beta CG10979 - CKII-beta CG10654 - CKII-beta CG6254 - CKII-beta odd - CKII-beta CG8159 - CKII-beta CG17802 - CKII-beta DIP:17378N - CKII-beta CG4496 - CkIIbeta2 CG4820 - CKII-beta DIP:17897N - CKII-beta CG6808 - CKII-beta CG18764 - CKII-beta CG18476 - CkIIbeta2 CG10959 - CKII-beta CG2129 - CKII-beta CG17801 - CKII-beta CG2116 - CKII-beta CG11696 - CKII-beta CG17568 - CKII-beta CG2678 - CKII-beta CG18011 - CKII-beta CG9797 - CKII-beta sug - CkIIbeta2 DIP:22012N - CKII-beta CG8301 - CKII-beta Sry-beta - CKII-beta CTCF - CkIIbeta2 CG3281 - CKII-beta CG4730 - CKII-beta CG7928 - CKII-beta CG7357 - CKII-beta CG8145 - CKII-beta	DIP:24379N - T01G9.6 DIP:24379N - DIP:24683N EOR-1 - T01G9.6 EOR-1 - DIP:24683N Y54E10BR.8 - T01G9.6 Y54E10BR.8 - DIP:24683N T09F3.1 - T01G9.6 T09F3.1 - DIP:24683N C07A12.1 - T01G9.6 C07A12.1 - DIP:24683N C27A12.2 - T01G9.6 C27A12.2 - DIP:24683N F53F8.1 - T01G9.6 R08E3.4 - T01G9.6 R08E3.4 - DIP:24683N F54F2.5 - T01G9.6 F54F2.5 - DIP:24683N ZK867.1 - T01G9.6 ZK867.1 - DIP:24683N	DIP:150N - CKB2 ADR1 - CKB1 Yer028c - CKB1 Fzf1 - CKB2 Fzf1 - CKB1 MIG1 - CKB1 Ygr067c - CKB1 RIM101 - CKB2 RIM101 - CKB1 Zap1 - CKB2
KOG1721 - KOG2294	opa - CG11799 opa - fd59A CG7752 - CG11799 Aef1 - foxo CG10654 - CG11799 D19B - jumu CG14451 - fd59A DIP:17332N - CG11799 DIP:17378N - fd59A GI:24653568 - CG11799 DIP:17897N - CG11799 CG6808 - fd59A CG15710 - fd64A CG10959 - CG11799 CG2129 - fd59A CG7987 - fd59A CG17801 - CG11799 CG11696 - fd64A CkIIalpha-i1 - fd64A l(2)35Ea - CG11799 CG2678 - fd59A CG9797 - fd59A CG9797 - CG11799 CG8301 - CG11799 CG8301 - fd59A Sry-beta - CG11799 CG1647 - fd64A CG4730 - CG11799 CG7928 - CG11799 CG7928 - fd59A CG7386 - fd59A CG10147 - jumu CG8145 - fd59A	F53B3.1 - T28H11.4	Swi5 - Fkh1 Swi5 - Fkh2p Swi5 - Hcm1p ADR1 - Fkh2p ADR1 - Hcm1 Yer028c - Hcm1 Fzf1 - Fkh1 MIG1 - Hcm1 Ygr067c - Hcm1 Ygr067c - Fkh2p RIM101 - Fkh1 Zap1 - Fkh1 Ace2 - Fkh1 Ace2 - Fkh2p Ace2 - Hcm1p
KOG1721 - KOG3565	DIP:121N - Cip4 CG10274 - Cip4 CG17612 - Cip4 D19A - Cip4 CG1233 - Cip4	C46E10.9 - F12F6.5	Ydr437w - BZZ1 Rgm1 - BZZ1 Msn4p - BZZ1
KOG1721 - KOG1844	DIP:121N - MBD-R2	F53B3.1 - DIP:24876N C27A12.2 - DIP:24876N F57C9.4 - DIP:24876N	DIP:150N - Cti6 ADR1 - Cti6 MIG1 - Cti6 RIM101 - Cti6 Nrg1p - Cti6
KOG1721 - KOG2005	DIP:121N - Rpn1	ZK892.7 - T22D1.9	Swi5 - Rpn1 ADR1 - Rpn1 Yer028c - Rpn1 MIG1 - Rpn1 Ygr067c - Rpn1 Ace2 - Rpn1
KOG1721 - KOG2151	wdn - CG6576 opa - CG6576 CG2052 - CG6576 DIP:17378N - CG6576 CG18764 - CG6576 DIP:18586N - CG6576 CG17801 - CG6576 CG9797 - CG6576 CG7386 - CG6576	C07A12.1 - B0286.4 C07A12.1 - DIP:26381N C07A12.1 - F44A2.1 ZK892.7 - B0286.4	ADR1 - Cdc36
KOG1721 - KOG3320	wdn - CG1883 CG10979 - CG1883 CG11247 - CG1883 odd - CG1883 DIP:17378N - CG1883 crol - CG1883 CG6792 - CG1883 CG11696 - CG1883 CG10462 - CG1883 CG2202 - CG1883 CG12391 - CG1883 DIP:21597N - CG1883 CG8301 - CG1883 CG7386 - CG1883 Sqz - CG1883	F54F2.5 - ZC434.2	ADR1 - Rps7b Yer028c - Rps7b MIG1 - Rps7b Ygr067c - Rps7b Ace2 - Rps7b
KOG1721 - KOG3780	CG40145 - CG3014 opa - CG14696 CG10267 - CG14696 odd - CG14696 DIP:17378N - CG14696 CG4820 - CG7047 D19A - CG14696 DIP:19658N - CG14696 CG2116 - CG14696 CG8301 - CG14696 hkb - CG14696 CG7386 - CG14696 CG7963 - CG14696 CG1792 - CG14696	ZK892.7 - Y17G7B.14 ZK892.7 - F48F7.7	Swi5 - Csr2 Swi5 - Yjl084c ADR1 - Csr2 Ace2 - Csr2 Ace2 - Yjl084c
KOG1721 - KOG1973	CG40145 - Bip2 opa - CG7379 CG10274 - CG7379 CG10267 - Bip2 CG17612 - Bip2 CG10543 - Bip2 MTF-1 - DIP:19186N MTF-1 - CG9293 CG4820 - CG6632 D19A - Bip2 D19A - CG7379 CG18476 - Bip2 su(Hw) - Bip2 DIP:19181N - DIP:19186N DIP:19181N - CG9293 CG10309 - Bip2 ken - Bip2 CG17568 - CG7379 CG10462 - Bip2 CG10462 - CG7379 EG:BACR42I17.11 - Bip2 CG2889 - Bip2 CG31365 - Bip2 CG4854 - Bip2 CG4936 - Bip2 Sry-delta - Bip2 CG7386 - Bip2 CG7386 - CG7379 CG10147 - Bip2 CG17806 - Bip2 CG11762 - Bip2 CG11798 - Bip2	EOR-1 - DIP:26104N	DIP:150N - Pho23 Swi5 - YNG2 ADR1 - Yng1 Ace2 - Yng1
KOG1074 - KOG1721	CG10274 - CG7386 CG10274 - CG8159 CG10274 - CG17568 CG10274 - CG4360 CG10274 - CG4854 CG10274 - CG8388 CG10274 - CG8301 CG10274 - CG3032 CG10274 - CG18764 CG10274 - D19A CG10274 - drm CG10274 - CG10267 CG10274 - Aef1 CG10274 - CG17612 CG10274 - CG1233 CG10274 - DIP:121N CG10274 - DIP:17378N CG10274 - CG7928 CG10274 - CG3281 CG10274 - CG9797 CG10274 - l(2)35Ea CG10274 - CG11696 CG10274 - CG10959 CG10274 - CG17802 CG10274 - CG7204 CG10274 - Sry-beta CG10274 - sug CG10274 - CG7987 CG6254 - DIP:22012N CG6254 - CG17801 CG6254 - CG9797 CG6254 - DIP:17378N CG6254 - CG17802 CG3941 - l(2)35Ea CG3941 - CG9609 CG3941 - CG11696 CG3941 - rgr CG3941 - CG10147 CG3941 - CG8301 CG3941 - CG7386 CG3941 - DIP:17897N CG3941 - CG10309 CG3941 - CG18476 CG3941 - Phol CG3941 - CG10543 CG3941 - D19B CG3941 - CG10654 CG2052 - zfh1 CG2052 - DIP:18586N CG2052 - odd CG2052 - CG8388 CG2052 - wdn CG2052 - CG8301 CG2052 - CG10267 CG6808 - DIP:17378N CG6808 - CG9797 CG6808 - CG7928 CG6808 - CG2116 CG6808 - CG10267 CG6808 - opa CG6808 - Sry-beta CG31782 - CG9797 CG31782 - CG1792 CG31782 - CG7357 CG31782 - CG7386 CG31782 - CG8301 CG31782 - DIP:17897N CG31782 - D19A CG31782 - CG10654 crol - CG1832 crol - CG18262 crol - CG10543 crol - CG11971 crol - D19B crol - CG8301 crol - CG12391 crol - CG2202 crol - DIP:21597N crol - CG4820 crol - CG8319 crol - CG7386 crol - CG10654 DIP:20799N - CG8159 DIP:21597N - CG8301 DIP:21597N - CG12391 DIP:21597N - CG2202 DIP:21597N - crol DIP:21597N - CG8319 DIP:21597N - CG7386 DIP:21597N - CG7987 DIP:21597N - DIP:17897N DIP:21597N - CG4820 DIP:21597N - DIP:121N	F15C11.1 - C07A12.1	Ydr437w - Msn4p
KOG1342 - KOG1721	dHDAC1 - pho dHDAC1 - Phol	C53A5.3 - F53B3.1	Hos2 - MIG1 Hos2 - Nrg1p Rpd3 - DIP:150N Rpd3 - Fzf1 Rpd3 - MIG1 Rpd3 - Nrg1p
KOG1507 - KOG1721	EG:BACR7A4.18 - hkb	D2096.8 - C07A12.1	NAP1 - Ygr067c
KOG1704 - KOG1721	Lmpt - sug Lmpt - CG7368 Lmpt - CG3032 Lmpt - CG17801 Lmpt - CG8145 stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) CG6522 - D19A CG6522 - CG11696 CG6522 - CG11695 CG6522 - su(Hw)	F28F5.3 - EOR-1 F28F5.3 - F54F2.5	RGA1 - Swi5 RGA1 - Ace2 Rga1 - ADR1 Rga1 - Swi5 Rga1 - Ace2
KOG0864 - KOG1721	CG11856 - CG10147 CG11856 - CG9609 CG11856 - su(Hw) CG11856 - D19A CG11856 - CG11696 CG11856 - CG11695 CG11856 - CG8301 CG11856 - CG10267 CG11856 - CG2052 CG11856 - DIP:18586N	F59A2.1 - C07A12.1	Yrb1 - Yer028c Yrb1 - Ace2 Yrb1 - ADR1 YRB2 - Nrg2 YRB2 - Ace2 NUP2 - Fzf1 NUP2 - MIG1 NUP2 - ADR1 NUP2 - Crz1p NUP2 - Swi5
KOG1703 - KOG1721	stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 unc-115 - bowl DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 CG30084 - CG3281 CG30084 - CG7357 CG30084 - DIP:17378N CG30084 - CG18011 CG30084 - CG17801 CG30084 - CG10959 CG30084 - CG8159 DIP:17944N - CG3281 DIP:17944N - CG7357 DIP:17944N - DIP:17378N DIP:17944N - CG18011 DIP:17944N - CG17801 DIP:17944N - CG10959 DIP:17944N - CG8159 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) DIP:21964N - bowl	Y65B4A.7 - ZK892.7 EAT-1 - F54F2.5 EAT-1 - EOR-1 EAT-1 - ZK867.1 EAT-1 - DIP:24379N EAT-1 - R08E3.4 EAT-1 - C27A12.2 EAT-1 - T09F3.1 EAT-1 - Y54E10BR.8 C28H8.6 - F54F2.5	Ykr090w - Swi5 Ykr090w - Ace2
KOG0668 - KOG1721	CKII-alpha - CG4820 CKII-alpha - opa CKII-alpha - CG10979 CKII-alpha - CG10654 CKII-alpha - CG8159 CKII-alpha - DIP:17897N CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	B0205.7 - F53F8.1	CKA1 - Fzf1 CKA1 - MIG1 CKA1 - DIP:150N CKA1 - Ygr067c CKA1 - RIM101 CKA2 - Crz1p CKA2 - Fzf1 CKA2 - RIM101
KOG0694 - KOG1721	Pk61C - CG7386 Pk61C - CG10979 DIP:20399N - CG10462 DIP:20399N - CG7386 DIP:20399N - CG10979 CG31140 - D19A CG31140 - CG8319 CG31140 - CG32767 CG31140 - l(2)35Ea CG31140 - CG7386 CG31140 - CG9797 CG31140 - odd Pkc98E - opa Pkc98E - zfh1 Pkc98E - DIP:18586N Pkc98E - CG2052 Pkc98E - odd CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	E01H11.1 - F53B3.1	Pkc1 - ADR1 Pkc1 - Swi5 Pkc1 - Ace2
KOG0676 - KOG1721	Arp87C - CG40145 Act87E - CG2678 Act87E - CG1647 Act87E - CG7386 Act87E - CG17801 Act87E - jing Act87E - CG7752 Act87E - CG7357 Act42A - CG33213 Act42A - sug Act42A - l(2)35Ea Act42A - opa Act42A - CG1792 Act42A - DIP:19658N Act42A - hkb Act42A - odd Act42A - CG8159 Act42A - CG17568 Act42A - CG18764 Arp11 - CG9797	T04C12.5 - F53B3.1 T04C12.5 - T09F3.1	actin - RIM101 actin - Swi5 ARP1 - Fzf1 ARP1 - Nrg2 Arp9p - Swi5
KOG0940 - KOG1721	CG7552 - DIP:17332N CG7552 - GI:24653568 CG7552 - CG8301 CG7552 - odd CG7552 - CG10267 CG3003 - CG7928 CG3003 - CG9793 CG3099 - DIP:17378N CG3099 - CG6808 CG3099 - CG8319 CG3099 - CG17568 CG3099 - CG2116 CG3099 - CG18476 CG3099 - DIP:19928N CG3099 - CG33213 CG3099 - CG7357 CG3099 - CG9797 CG3099 - CG8301 Nedd4 - CG9817 Nedd4 - CG1832 Nedd4 - CG18262 Nedd4 - crol Nedd4 - CG10543 Nedd4 - CG11971 Nedd4 - D19B Su(dx) - DIP:17332N Su(dx) - CG4820 Su(dx) - GI:24653568	Y65B4BR.4 - ZK867.1 Y65B4BR.4 - DIP:24379N Y65B4BR.4 - F54F2.5 Y65B4BR.4 - R08E3.4 Y65B4BR.4 - C27A12.2 Y65B4BR.4 - T09F3.1 Y65B4BR.4 - Y54E10BR.8 Y65B4BR.4 - ZK892.7 F13E6.4 - ZK867.1 F13E6.4 - DIP:24379N F13E6.4 - F54F2.5 F13E6.4 - R08E3.4 F13E6.4 - C27A12.2 F13E6.4 - T09F3.1 F13E6.4 - Y54E10BR.8	Rsp5 - Nrg2 Rsp5 - RIM101
KOG0749 - KOG1721	DIP:19903N - pho Ant2 - CG18476 Ant2 - opa Ant2 - CG8301 Ant2 - DIP:17332N Ant2 - GI:24653568 Ant2 - CG7752 Ant2 - CG5245 Ant2 - CG8319 Ant2 - CG11247 Ant2 - CG10979	DIP:26442N - ZK867.1 DIP:26442N - DIP:24379N DIP:26442N - F54F2.5 DIP:26442N - R08E3.4 DIP:26442N - C27A12.2 DIP:26442N - T09F3.1 DIP:26442N - Y54E10BR.8 F25B4.7 - ZK867.1 F25B4.7 - DIP:24379N F25B4.7 - F54F2.5 F25B4.7 - R08E3.4 F25B4.7 - C27A12.2 F25B4.7 - T09F3.1 F25B4.7 - Y54E10BR.8 T27E9.1 - EOR-1	Pet9p - ADR1 AAC1 - Yer028c
KOG0841 - KOG1721	14-3-3-epsilon - CG10979 14-3-3-epsilon - CG9797 14-3-3-epsilon - CG6808 14-3-3-epsilon - CG2889 14-3-3-epsilon - CG10267 14-3-3-epsilon - DIP:22690N 14-3-3-epsilon - EP2237 14-3-3-epsilon - Aef1 14-3-3-epsilon - Sqz	PAR-5 - F47H4.1 PAR-5 - F54H5.4 ftt-2 - F53B3.1 F52D10.3 - F53B3.1	Bmh2 - ADR1 BMH1 - ADR1 BMH1 - Fzf1
KOG0740 - KOG1721	CG12010 - CG8159 CG12010 - CkIIalpha-i1	F32D1.1 - F57C9.4 F32D1.1 - C27A12.2 F32D1.1 - F53B3.1	SAP1 - RIM101
KOG1279 - KOG1721	mor - EG:BACR42I17.11 mor - Sry-delta mor - CG10147 mor - CG11798 mor - CG4936 mor - CG10309 mor - su(Hw) mor - CG18476 mor - D19A mor - CG10543 mor - CG8301 mor - CG10267 mor - CG2052 mor - DIP:18586N	Y113G7B.23 - C07A12.1 Y113G7B.23 - F47H4.1 Y113G7B.23 - F54H5.4 Y113G7B.23 - EOR-1	RSC8 - Swi5 SWI3 - Swi5
KOG0581 - KOG1721	CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	MEK-2 - F54F2.5	Pbs2 - ADR1 Mkk2 - ADR1 Mkk2 - Nrg2
KOG1290 - KOG1721	Doa - CG2678 BEST:CK01209 - CG8301 BEST:CK01209 - zfh1 BEST:CK01209 - DIP:18586N BEST:CK01209 - CG2052 BEST:CK01209 - odd BEST:CK01209 - CG7987 BEST:CK01209 - opa BEST:CK01209 - D19A BEST:CK01209 - CG2116 BEST:CK01209 - CG6792 BEST:CK01209 - EG:BACR42I17.11 BEST:CK01209 - Sry-delta BEST:CK01209 - CG10147 BEST:CK01209 - CG11798 BEST:CK01209 - CG4936 BEST:CK01209 - CG10309 BEST:CK01209 - su(Hw) BEST:CK01209 - CG18476 BEST:CK01209 - CG10543 BEST:CK01209 - Sry-beta BEST:CK01209 - CG6808 DIP:21245N - su(Hw) mnb - su(Hw)	B0464.5 - F57C9.4 B0464.5 - C27A12.2 B0464.5 - F53B3.1 B0464.5 - ZK867.1 B0464.5 - DIP:24379N B0464.5 - F54F2.5 B0464.5 - R08E3.4 B0464.5 - T09F3.1 B0464.5 - Y54E10BR.8 B0464.5 - ZK892.7 spk-1 - F57C9.4 spk-1 - C27A12.2 spk-1 - F53B3.1 spk-1 - ZK867.1 spk-1 - DIP:24379N spk-1 - F54F2.5 spk-1 - R08E3.4 spk-1 - T09F3.1 spk-1 - Y54E10BR.8 spk-1 - ZK892.7	Pho85p - ADR1 Pho85p - Swi5
KOG1466 - KOG1721	eIF2B-delta - jing eIF2B-delta - CG7752 eIF2B-delta - Sry-beta	ZK1098.4 - C07A12.1 ZK1098.4 - F57C9.4 ZK1098.4 - C27A12.2 ZK1098.4 - F53B3.1 ZK1098.4 - F54F2.5 ZK1098.4 - ZK892.7	Gcn3 - Crz1p Gcn3 - Ygr067c Gcn3 - Yer028c Gcn3 - RIM101
KOG1164 - KOG1721	BcDNA:LD23371 - CG5245 dco - jing dco - CG7752	F46F2.2 - F54F2.5 K04C1.5 - F54H5.4	Hrr25 - Crz1p
KOG0660 - KOG1290	CG30171 - BEST:CK01209	MPK-1 - spk-1 MPK-1 - B0464.5	Slt2 - Sky1
KOG0660 - KOG1164	CG30171 - dco	MPK-1 - F46F2.2	Kss1 - Hrr25 Slt2 - Hrr25 Smk1 - Hrr25
KOG0660 - KOG1466	CG30171 - eIF2B-delta	MPK-1 - ZK1098.4	Kss1 - Gcn3 Slt2 - Gcn3 Smk1 - Gcn3
KOG0660 - KOG1721	p38b - Sry-beta p38b - CG8159 p38b - CG3281 p38b - CG17568 p38b - CG18764 p38b - CG10274 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	B0218.3 - ZK892.7 MPK-1 - ZK892.7 MPK-1 - F54F2.5	Kss1 - Ygr067c Slt2 - Ygr067c Slt2 - MIG1 Slt2 - Yer028c Slt2 - ADR1 Hog1 - DIP:150N Hog1 - MIG1 Smk1 - Ygr067c Smk1 - MIG1 Smk1 - Yer028c Smk1 - ADR1
KOG0660 - KOG0960	CG30171 - CG3731	MPK-1 - F56D2.1	Slt2 - COR1 Smk1 - COR1
KOG0867 - KOG0960	GstD9 - CG3731	F17C11.9 - F56D2.1	URE2 - COR1 Tef4p - COR1

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Conserved subnet 5:
28 conserved interactions between 26 ortholog groups.
This subnet exists in 3 organisms (p<6e-34).

Ortholog Groups
KOG0668	Casein kinase II, alpha subunit
KOG3092	Casein kinase II, beta subunit
KOG2169	Zn-finger transcription factor
KOG2294	Transcription factor of the Forkhead/HNF3 family
KOG0653	Cyclin B and related kinase-activating proteins
KOG3484	Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins
KOG0580	Serine/threonine protein kinase
KOG0594	Protein kinase PCTAIRE and related kinases
KOG2996	Rho guanine nucleotide exchange factor VAV3
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG3320	40S ribosomal protein S7
KOG0676	Actin and related proteins
KOG0749	Mitochondrial ADP/ATP carrier proteins
KOG1721	FOG: Zn-finger
KOG2330	Splicing factor 3b, subunit 2
KOG1973	Chromatin remodeling protein, contains PHD Zn-finger
KOG1074	Transcriptional repressor SALM
KOG1342	Histone deacetylase complex, catalytic component RPD3
KOG1704	FOG: LIM domain
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG0841	Multifunctional chaperone (14-3-3 family)
KOG2177	Predicted E3 ubiquitin ligase
KOG1947	Leucine rich repeat proteins, some proteins contain F-box
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0660	Mitogen-activated protein kinase
KOG0658	Glycogen synthase kinase-3

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0668 - KOG3092	CK2alpha - Casein Kinase Ii CK2-alpha' subunit - Casein Kinase Ii	B0205.7 - T01G9.6	CKA1 - CKB2 CKA1 - CKB1 CKA2 - CKB2 CKA2 - CKB1
KOG2169 - KOG2294	PIAS1 - FoxO1 PIAS1 - FoxO3 PIAS1 - FoxO4	DIP:26255N - DAF-16	NFI1 - Fhl1
KOG0653 - KOG3484	Cyclin B1 - CKS1B cyclin B2 - CKS1B	DIP:24822N - C09G4.3 R02F2.1 - C09G4.3 H31G24.4 - C09G4.3	Clb3 - CKS1 Clb3 - DIP:102N Clb1 - CKS1 Clb1 - DIP:102N Clb6 - DIP:102N Clb6 - CKS1 Clb4 - CKS1 Clb4 - DIP:102N Cln1 - CKS1 Cln1 - DIP:102N Cln2 - CKS1 Cln2 - DIP:102N Clb2 - CKS1 Clb2 - DIP:102N Clb5 - CKS1 Clb5 - DIP:102N Cln3 - CKS1 Cln3 - DIP:102N
KOG0580 - KOG0594	STK6 - CDC2 HsAIRK-2 - PFTK1 HsAIRK-2 - CDK6 HsAIRK-2 - CDK4	K07C11.2 - T05G5.3	Ipl1 - Cdc28 Ipl1 - Cak1
KOG0594 - KOG2996	DIP:133N - Vav CDK4 - p55alpha CDK6 - p55alpha CDK2 - p55alpha	T05G5.3 - C35B8.2	Cdc28 - Cdc24p
KOG0594 - KOG1703	CDK4 - ARA55 CDK2 - ARA55	T05G5.3 - C34B2.4	Cdc28 - Ykr090w Cak1 - Ykr090w
KOG1703 - KOG3320	PXN - RPS7 paxillin - RPS7 ARA55 - RPS7	Y65B4A.7 - ZC434.2 EAT-1 - ZC434.2 C28H8.6 - ZC434.2	LRG - Rps7a
KOG0676 - KOG0749	ACTG1 - SLC25A5 ACTC - SLC25A5	Y53F4B.22 - T27E9.1	actin - Aac3p
KOG1721 - KOG3484	KLF6 - CKS1B	ZK892.7 - Y71G12B.27	Swi5 - DIP:102N Swi5 - CKS1 Ace2 - DIP:102N Ace2 - CKS1
KOG1721 - KOG2330	PLZF - SF3b2 ZNF83 - SF3b2 PRDM4 - SF3b2 FLJ12586 - SF3b2 SIP1 - SF3b2 HIVEP1 - SF3b2 PLAGL1 - SF3b2 PLAG1 - SF3b2	F53B3.1 - W03F9.10 C27A12.2 - W03F9.10 F57C9.4 - W03F9.10	Swi5 - Cus1 MIG1 - Cus1 Nrg1p - Cus1
KOG1721 - KOG2294	PLZF - FoxO3 PLZF - FoxH1 PLZF - FoxO1 PLZF - FoxO4 ZNF83 - FoxO3 ZNF83 - FoxH1 ZNF83 - FoxO1 ZNF83 - FoxO4 PRDM4 - FoxO3 PRDM4 - FoxH1 PRDM4 - FoxO1 PRDM4 - FoxO4 FLJ12586 - FoxO3 FLJ12586 - FoxH1 FLJ12586 - FoxO1 FLJ12586 - FoxO4 SIP1 - FoxO3 SIP1 - FoxH1 SIP1 - FoxO1 SIP1 - FoxO4 HIVEP1 - FoxO3 HIVEP1 - FoxH1 HIVEP1 - FoxO1 HIVEP1 - FoxO4 PLAGL1 - FoxO3 PLAGL1 - FoxH1 PLAGL1 - FoxO1 PLAGL1 - FoxO4 PLAG1 - FoxO3 PLAG1 - FoxH1 PLAG1 - FoxO1 PLAG1 - FoxO4	F53B3.1 - T28H11.4	Swi5 - Fkh1 Swi5 - Fkh2p Swi5 - Hcm1p ADR1 - Fkh2p ADR1 - Hcm1 Yer028c - Hcm1 Fzf1 - Fkh1 MIG1 - Hcm1 Ygr067c - Hcm1 Ygr067c - Fkh2p RIM101 - Fkh1 Zap1 - Fkh1 Ace2 - Fkh1 Ace2 - Fkh2p Ace2 - Hcm1p
KOG1721 - KOG1973	IMAGE 3948563 - ING1L YY1 - p28ING5 YY1 - ING4 ZNF76 - ING1L SIP1 - ING1L Egr1 - p28ING5 Egr1 - ING4 KIAA0972 - ING1L	EOR-1 - DIP:26104N	DIP:150N - Pho23 Swi5 - YNG2 ADR1 - Yng1 Ace2 - Yng1
KOG1074 - KOG1721	FLJ20765 - E4F1 FLJ20765 - ZF6 FLJ20765 - SIP1 FLJ20765 - ZNF83 IMAGE 3948563 - SIP1 IMAGE 3948563 - KIAA0972 IMAGE 3948563 - ZNF76 KIAA0972 - IMAGE 3948563 KIAA0972 - SIP1 KIAA0972 - ZNF76 ZF6 - E4F1 ZF6 - SIP1 ZF6 - ZNF83 ZF6 - FLJ20765	F15C11.1 - C07A12.1	Ydr437w - Msn4p
KOG1342 - KOG1721	Rpd3p - YY1 Rpd3p - DIP:36N HDAC2 - YY1 HDAC2 - PLZF HDAC2 - Sp1 HDAC2 - DIP:36N HDAC1 - PLZF HDAC1 - DIP:5990N HDAC1 - Miz-1 HDAC1 - AEBP2 HDAC1 - Sp1 HDAC3 - BCL6 HDAC3 - zid HDAC3 - PLZF	C53A5.3 - F53B3.1	Hos2 - MIG1 Hos2 - Nrg1p Rpd3 - DIP:150N Rpd3 - Fzf1 Rpd3 - MIG1 Rpd3 - Nrg1p
KOG1704 - KOG1721	TES - ZNF510 PINCH-2 - ZFD25 FHL2 - ZNF36	F28F5.3 - EOR-1 F28F5.3 - F54F2.5	RGA1 - Swi5 RGA1 - Ace2 Rga1 - ADR1 Rga1 - Swi5 Rga1 - Ace2
KOG1703 - KOG1721	paxillin - ZNF510 paxillin - CTCF ARA55 - PLAG1 ARA55 - HIVEP1 ARA55 - SIP1 ARA55 - ZNF83 ARA55 - FLJ12586 ARA55 - PLAGL1 ARA55 - PRDM4 ARA55 - PLZF ARA55 - ZFD25 PINCH-2 - ZFD25 DIP:5931N - DIP:5990N	Y65B4A.7 - ZK892.7 EAT-1 - F54F2.5 EAT-1 - EOR-1 EAT-1 - ZK867.1 EAT-1 - DIP:24379N EAT-1 - R08E3.4 EAT-1 - C27A12.2 EAT-1 - T09F3.1 EAT-1 - Y54E10BR.8 C28H8.6 - F54F2.5	Ykr090w - Swi5 Ykr090w - Ace2
KOG0668 - KOG1721	CK2-alpha' subunit - OSR1	B0205.7 - F53F8.1	CKA1 - Fzf1 CKA1 - MIG1 CKA1 - DIP:150N CKA1 - Ygr067c CKA1 - RIM101 CKA2 - Crz1p CKA2 - Fzf1 CKA2 - RIM101
KOG0676 - KOG1721	ACTG1 - ZNF510 ACTG1 - HIVEP1 ACTG1 - zid ACTC - HIVEP1 ACTC - ZNF510	T04C12.5 - F53B3.1 T04C12.5 - T09F3.1	actin - RIM101 actin - Swi5 ARP1 - Fzf1 ARP1 - Nrg2 Arp9p - Swi5
KOG0940 - KOG1721	NEDD4 - IMAGE 3948563 NEDD4 - SIP1 NEDD4 - KIAA0972 NEDD4 - ZNF76 KIAA1301 - IMAGE 3948563 KIAA1301 - SIP1 KIAA1301 - KIAA0972 KIAA1301 - ZNF76 FLJ32109 - SIP1 SMURF2 - ZFD25 SMURF2 - ZNF-U69274 SMURF2 - PLAG1 SMURF2 - HIVEP1 SMURF2 - SIP1 SMURF2 - ZNF83 SMURF2 - FLJ12586 SMURF2 - PLAGL1 SMURF2 - PRDM4 SMURF2 - PLZF SMURF2 - IMAGE 3948563 SMURF2 - KIAA0972 SMURF2 - ZNF76 SMURF1 - ZFD25 SMURF1 - ZNF-U69274 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76	Y65B4BR.4 - ZK867.1 Y65B4BR.4 - DIP:24379N Y65B4BR.4 - F54F2.5 Y65B4BR.4 - R08E3.4 Y65B4BR.4 - C27A12.2 Y65B4BR.4 - T09F3.1 Y65B4BR.4 - Y54E10BR.8 Y65B4BR.4 - ZK892.7 F13E6.4 - ZK867.1 F13E6.4 - DIP:24379N F13E6.4 - F54F2.5 F13E6.4 - R08E3.4 F13E6.4 - C27A12.2 F13E6.4 - T09F3.1 F13E6.4 - Y54E10BR.8	Rsp5 - Nrg2 Rsp5 - RIM101
KOG0749 - KOG1721	SLC25A5 - HIVEP1	DIP:26442N - ZK867.1 DIP:26442N - DIP:24379N DIP:26442N - F54F2.5 DIP:26442N - R08E3.4 DIP:26442N - C27A12.2 DIP:26442N - T09F3.1 DIP:26442N - Y54E10BR.8 F25B4.7 - ZK867.1 F25B4.7 - DIP:24379N F25B4.7 - F54F2.5 F25B4.7 - R08E3.4 F25B4.7 - C27A12.2 F25B4.7 - T09F3.1 F25B4.7 - Y54E10BR.8 T27E9.1 - EOR-1	Pet9p - ADR1 AAC1 - Yer028c
KOG0841 - KOG1721	14-3-3-epsilon - BCL6 14-3-3-epsilon - PLZF 14-3-3tau - E4F1 14-3-3tau - ZF6 14-3-3tau - SIP1 14-3-3tau - ZNF83 14-3-3tau - FLJ20765	PAR-5 - F47H4.1 PAR-5 - F54H5.4 ftt-2 - F53B3.1 F52D10.3 - F53B3.1	Bmh2 - ADR1 BMH1 - ADR1 BMH1 - Fzf1
KOG1721 - KOG2177	FLJ23392 - FLJ10759 YY1 - cPML PLZF - cPML ZFP106 - FLJ10759 ZNF83 - cPML zid - FLJ10759 PRDM4 - cPML FLJ12586 - cPML OSR1 - cPML COASTER - Sp100 SIP1 - cPML SIP1 - FLJ10759 HIVEP1 - cPML CTIP2 - Sp100 PLAGL1 - cPML Sp1 - cPML PLAG1 - cPML	DIP:24379N - C06A5.9 Y54E10BR.8 - C06A5.9 T09F3.1 - C06A5.9 F53B3.1 - ZK112.2 F53B3.1 - C06A5.9 F53B3.1 - F26G5.9 C27A12.2 - ZK112.2 C27A12.2 - C06A5.9 C27A12.2 - F26G5.9 R08E3.4 - C06A5.9 F54F2.5 - C06A5.9 F54F2.5 - ZK112.2 ZK892.7 - ZK112.2 ZK867.1 - C06A5.9 F57C9.4 - ZK112.2 F57C9.4 - C06A5.9 F57C9.4 - F26G5.9	Ygr067c - Psh1p DIP:6487N - Psh1p
KOG1721 - KOG1947	ZNF-U69274 - FBXL11 IMAGE 3948563 - FBXL12 PLZF - FBXL11 ZNF76 - FBXL12 TIEG - FBXL11 ZNF83 - FBXL11 PRDM4 - FBXL11 FLJ12586 - FBXL11 OSR1 - FBXL12 SIP1 - FBXL11 SIP1 - FBXL12 KIAA0972 - FBXL12 ZFD25 - FBXL11 HIVEP1 - FBXL11 PLAGL1 - FBXL11 PLAG1 - FBXL11	T09F3.1 - B0393.3 F53B3.1 - B0393.3	Swi5 - Grr1 ADR1 - Grr1 Ygr067c - Grr1 RIM101 - Grr1 Ace2 - Grr1
KOG0581 - KOG1721	MEK2 - ZNF7 MEK1 - ZNF7	MEK-2 - F54F2.5	Pbs2 - ADR1 Mkk2 - ADR1 Mkk2 - Nrg2
KOG0581 - KOG0660	MKK5 - ERK5 MEK2 - ERK2 MEK2 - Erk1 MEK1 - ERK2 MEK1 - Erk1	MEK-2 - MPK-1	Ste7 - Kss1 Ste7 - Fus3 Ste7 - Slt2 Pbs2 - Hog1 Pbs2 - Kss1 Pbs2 - Fus3 Mkk1 - Slt2 Mkk1 - Smk1 Mkk2 - Slt2 Mkk2 - Kss1 Mkk2 - Smk1
KOG0660 - KOG1721	Erk1 - ZNF7 Erk1 - Sp1 Erk1 - YY1 p38-2 - YY1	B0218.3 - ZK892.7 MPK-1 - ZK892.7 MPK-1 - F54F2.5	Kss1 - Ygr067c Slt2 - Ygr067c Slt2 - MIG1 Slt2 - Yer028c Slt2 - ADR1 Hog1 - DIP:150N Hog1 - MIG1 Smk1 - Ygr067c Smk1 - MIG1 Smk1 - Yer028c Smk1 - ADR1
KOG0660 - KOG2996	ERK2 - Vav	B0218.3 - C35B8.2	Fus3 - Cdc24p Slt2 - Cdc24p
KOG0658 - KOG0660	DIP:878N - p38-2 DIP:878N - ERK2 GSK3-alpha - Erk1 GSK3-beta - Erk1	Y18D10A.5 - B0218.3 Y18D10A.5 - MPK-1	RIM11 - Kss1 Yol128c - Slt2

---

Conserved subnet 6:
19 conserved interactions between 17 ortholog groups.
This subnet exists in 3 organisms (p<3e-35).

Ortholog Groups
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG0676	Actin and related proteins
KOG0819	Annexin
KOG1721	FOG: Zn-finger
KOG4333	Nuclear DEAF-1 related transcriptional regulator (suppressin) and related SAND domain proteins
KOG3575	FOG: Hormone receptors
KOG0594	Protein kinase PCTAIRE and related kinases
KOG2330	Splicing factor 3b, subunit 2
KOG3302	TATA-box binding protein (TBP), component of TFIID and TFIIIB
KOG2996	Rho guanine nucleotide exchange factor VAV3
KOG4637	Adaptor for phosphoinositide 3-kinase
KOG3701	TGFbeta receptor signaling protein SMAD and related proteins
KOG3544	Collagens (type IV and type XIII), and related proteins
KOG0660	Mitogen-activated protein kinase
KOG0603	Ribosomal protein S6 kinase
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Caenorhabditis elegans
KOG0940 - KOG1703	Smurf1 - Cypher1	SMURF2 - ARA55 SMURF1 - CLP-36 SMURF1 - ARA55 SMURF1 - ARA55	Y65B4BR.4 - EAT-1 F13E6.4 - EAT-1 F13E6.4 - C28H8.6
KOG0676 - KOG1703	Actin beta - Cypher1	ACTG1 - paxillin ACTG1 - ARA55 ACTG1 - PXN ACTC - paxillin	T04C12.5 - Y65B4A.7
KOG0819 - KOG1703	Annexin II - Cypher1	ANXA2 - paxillin ANXA2 - ARA55 ANXA2 - PXN	ZC155.1 - EAT-1
KOG1721 - KOG4333	ZAC1 - GMEB1	IMAGE 3948563 - GMEB1 PLZF - GMEB1 ZNF76 - GMEB1 ZNF83 - GMEB1 zid - GMEB1 PRDM4 - GMEB1 FLJ12586 - GMEB1 COASTER - GMEB1 SIP1 - GMEB1 KIAA0972 - GMEB1 HIVEP1 - GMEB1 PLAGL1 - GMEB1 PLAG1 - GMEB1	T09F3.1 - C25G4.4 F53B3.1 - C25G4.4
KOG1721 - KOG3575	ZAC1 - DIP:125N ZAC1 - GI:6679695 ZAC1 - GI:7304901 BCL-6 - PPAR-delta	DIP:36N - VDR FLJ20765 - PPARD YY1 - ER-alpha YY1 - DIP:1044N YY1 - VDR Miz-1 - ER-alpha Miz-1 - ER-beta Miz-1 - DIP:622N PLZF - ER-alpha PLZF - PPARD PLZF - VDR PLZF - ER-beta PLZF - RAR ZNF83 - PPARD ZNF83 - VDR zid - PPARD zid - ER-alpha CTCF - RXR-beta PRDM4 - VDR FLJ12586 - VDR SIP1 - PPARD SIP1 - VDR SIP1 - RARB SIP1 - RXR-alpha Egr1 - ER-beta Egr1 - RAR Egr1 - ER-alpha DIP:5990N - ER-alpha DIP:5990N - DIP:622N DIP:5990N - ER-beta DIP:5990N - DIP:5999N DIP:5990N - RXR-beta ZF6 - PPARD ZFD25 - NR2F2 HIVEP1 - VDR E4F1 - PPARD BCL6 - PPARD BCL6 - ER-alpha PLAGL1 - VDR Sp1 - ER-beta Sp1 - RAR Sp1 - ER-alpha Sp1 - RXR-alpha PLAG1 - VDR	DIP:24379N - Y15E3A.1 DIP:24379N - R04B5.4 DIP:24379N - nhr-13 DIP:24379N - F44G3.9 DIP:24379N - C26B2.3 EOR-1 - F44G3.9 EOR-1 - C45E5.6 Y54E10BR.8 - R04B5.4 Y54E10BR.8 - nhr-13 Y54E10BR.8 - F44G3.9 Y54E10BR.8 - C26B2.3 F54H5.4 - F44C8.11 F54H5.4 - nhr-2 T09F3.1 - R04B5.4 T09F3.1 - nhr-13 T09F3.1 - F44G3.9 T09F3.1 - C26B2.3 T22C8.3 - F44G3.9 F53B3.1 - F44G3.9 F53B3.1 - Y45G5AM.1 C07A12.1 - Y15E3A.1 C07A12.1 - R04B5.4 C07A12.1 - Y45G5AM.1 C07A12.1 - nhr-13 F47H4.1 - nhr-2 C27A12.2 - F44G3.9 C27A12.2 - Y45G5AM.1 C27A12.2 - R04B5.4 C27A12.2 - nhr-13 C27A12.2 - C26B2.3 R08E3.4 - R04B5.4 R08E3.4 - nhr-13 R08E3.4 - F44G3.9 R08E3.4 - C26B2.3 F54F2.5 - F44G3.9 F54F2.5 - R04B5.4 F54F2.5 - nhr-13 F54F2.5 - C26B2.3 ZK892.7 - F44G3.9 ZK867.1 - Y15E3A.1 ZK867.1 - F44G3.9 ZK867.1 - R04B5.4 ZK867.1 - nhr-13 ZK867.1 - C26B2.3 F57C9.4 - F44G3.9 F57C9.4 - Y45G5AM.1 C46E10.9 - C26B2.3
KOG0594 - KOG3575	CDK4 - GI:6679695 CDK4 - GI:7304901	CDC2 - ER-alpha CDC2 - DIP:1044N CDK4 - VDR CDK4 - ER-alpha CDK4 - RARB CDK4 - RXR-alpha CDK4 - GI:21322252 CDK6 - VDR CDK6 - RAR CDK6 - GI:21322252 CDK2 - VDR CDK2 - ER-alpha CDK2 - RARB CDK2 - RXR-alpha CDK2 - GI:21322252	T05G5.3 - C08F8.8
KOG3575 - KOG3575	RXRA - RXRA GI:7304901 - GI:6679695 GI:6679695 - GI:7304901 Esrrg - Esrrg	DIP:158N - RXR-alpha DIP:158N - VDR DIP:158N - NR1H4 DIP:158N - PPAR-alpha DIP:158N - RAR DIP:158N - PPARG PPAR-gamma-2 - LXR-alpha PPAR-gamma-2 - ER-alpha PPAR-gamma-2 - GI:21322252 PPAR-gamma-2 - ER-beta PPAR-gamma-2 - PPAR-alpha PPAR-gamma-2 - PPARG PPARG - RXR-alpha PPARG - PPARG PPARG - VDR PPARG - NR1H4 PPARG - DIP:158N PPARG - PPAR-alpha PPARG - RAR PPARG - ER-alpha PPARG - GI:21322252 PPARG - ER-beta PPARG - PPAR-gamma-2 RAR - RXR-alpha RAR - PPAR-alpha RAR - VDR RAR - ER-alpha RAR - GI:21322252 RAR - NR1H4 RAR - DIP:158N RAR - PPARG RAR - ER-beta DIP:622N - ER-alpha DIP:622N - ER-beta RXR-alpha - VDR RXR-alpha - RXR-alpha RXR-alpha - NR1H4 RXR-alpha - DIP:158N RXR-alpha - PPAR-alpha RXR-alpha - RAR RXR-alpha - PPARG RXR-alpha - ER-alpha RXR-alpha - GI:21322252 RXR-alpha - RARB RXR-alpha - ER-beta DIP:1044N - ER-alpha RARB - RXR-alpha ER-beta - ER-alpha ER-beta - DIP:622N ER-beta - RAR ER-beta - GI:21322252 ER-beta - PPAR-alpha ER-beta - PPARG ER-beta - PPAR-gamma-2 ER-beta - RXR-alpha VDR - VDR VDR - RXR-alpha VDR - RAR VDR - ER-alpha VDR - GI:21322252 VDR - NR1H4 VDR - DIP:158N VDR - PPAR-alpha VDR - PPARG PPAR-alpha - PPAR-alpha PPAR-alpha - RXR-alpha PPAR-alpha - RAR PPAR-alpha - ER-alpha PPAR-alpha - GI:21322252 PPAR-alpha - ER-beta PPAR-alpha - PPARG PPAR-alpha - PPAR-gamma-2 PPAR-alpha - VDR PPAR-alpha - NR1H4 PPAR-alpha - DIP:158N LXR-alpha - PPAR-gamma-2 RXR-beta - RXR-beta RXR-beta - ER-alpha CAR - ER-alpha GI:21322252 - ER-alpha GI:21322252 - VDR GI:21322252 - RXR-alpha GI:21322252 - RAR GI:21322252 - ER-beta GI:21322252 - PPAR-alpha GI:21322252 - PPARG GI:21322252 - PPAR-gamma-2 NR1H4 - RXR-alpha NR1H4 - VDR NR1H4 - DIP:158N NR1H4 - PPAR-alpha NR1H4 - RAR NR1H4 - PPARG ER-alpha - ER-alpha ER-alpha - DIP:622N ER-alpha - ER-beta ER-alpha - RAR ER-alpha - RXR-beta ER-alpha - LRH-1 ER-alpha - GI:21322252 ER-alpha - VDR ER-alpha - RXR-alpha ER-alpha - CAR ER-alpha - DIP:1044N ER-alpha - PPAR-alpha ER-alpha - PPARG ER-alpha - PPAR-gamma-2 PPARD - PPARD LRH-1 - ER-alpha	F58G6.5 - nhr-34 nhr-2 - C08F8.8 nhr-2 - F43C1.4 nhr-61 - nhr-4 C08F8.8 - nhr-2 C08F8.8 - F44G3.9 Y45G5AM.1 - F44G3.9 Y45G5AM.1 - R04B5.4 nhr-34 - F58G6.5 nhr-1 - R09G11.2 nhr-4 - nhr-61 nhr-4 - C26B2.3 Y80D3A.4 - C27C7.4 Y80D3A.4 - nhr-71 Y80D3A.4 - nhr-13 Y80D3A.4 - Y38E10A.18 Y80D3A.4 - NHR-22 Y80D3A.4 - ZK1037.5 Y80D3A.4 - ZK697.2 C26B2.3 - R04B5.4 C26B2.3 - nhr-13 C26B2.3 - F44G3.9 C26B2.3 - nhr-4 ZK697.2 - C27C7.4 ZK697.2 - nhr-71 ZK697.2 - nhr-13 ZK697.2 - Y38E10A.18 ZK697.2 - NHR-22 ZK697.2 - ZK1037.5 ZK697.2 - Y80D3A.4 ZK1037.5 - C27C7.4 ZK1037.5 - nhr-71 ZK1037.5 - nhr-13 ZK1037.5 - Y38E10A.18 ZK1037.5 - NHR-22 ZK1037.5 - ZK697.2 ZK1037.5 - Y80D3A.4 NHR-22 - C27C7.4 NHR-22 - nhr-71 NHR-22 - nhr-13 NHR-22 - Y38E10A.18 NHR-22 - ZK1037.5 NHR-22 - ZK697.2 NHR-22 - Y80D3A.4 NHR-22 - R04B5.4 C45E5.6 - F44G3.9 nhr-13 - C27C7.4 nhr-13 - nhr-71 nhr-13 - Y38E10A.18 nhr-13 - NHR-22 nhr-13 - ZK1037.5 nhr-13 - ZK697.2 nhr-13 - Y80D3A.4 nhr-13 - R04B5.4 nhr-13 - F44G3.9 nhr-13 - C26B2.3 F16B4.9 - T06C12.13 F16B4.9 - F44G3.9 nhr-71 - C27C7.4 nhr-71 - nhr-13 nhr-71 - Y38E10A.18 nhr-71 - NHR-22 nhr-71 - ZK1037.5 nhr-71 - ZK697.2 nhr-71 - Y80D3A.4 Y38E10A.18 - C27C7.4 Y38E10A.18 - nhr-71 Y38E10A.18 - nhr-13 Y38E10A.18 - NHR-22 Y38E10A.18 - ZK1037.5 Y38E10A.18 - ZK697.2 Y38E10A.18 - Y80D3A.4 F44G3.9 - F44G3.9 F44G3.9 - T06C12.13 F44G3.9 - F16B4.9 F44G3.9 - R04B5.4 F44G3.9 - nhr-13 F44G3.9 - C26B2.3 F44G3.9 - Y45G5AM.1 F44G3.9 - C45E5.6 F44G3.9 - C08F8.8 F44G3.9 - B0280.8 C11G6.4 - C33G8.6 F43C1.4 - nhr-2 R09G11.2 - nhr-1 B0280.8 - B0280.8 B0280.8 - F44G3.9 R04B5.4 - Y45G5AM.1 R04B5.4 - NHR-22 R04B5.4 - nhr-13 R04B5.4 - F44G3.9 R04B5.4 - C26B2.3 C33G8.6 - C11G6.4 C27C7.4 - nhr-71 C27C7.4 - nhr-13 C27C7.4 - Y38E10A.18 C27C7.4 - NHR-22 C27C7.4 - ZK1037.5 C27C7.4 - ZK697.2 C27C7.4 - Y80D3A.4 T06C12.13 - F44G3.9 T06C12.13 - F16B4.9
KOG2330 - KOG3575	SF3b2 - VDR	SF3b2 - VDR	W03F9.10 - F44G3.9 W03F9.10 - Y45G5AM.1
KOG3302 - KOG3575	TBP - GI:7304901 DIP:24197N - GI:7304901 DIP:1078N - GI:7304901	TBP - VDR TBP - ER-alpha TBP - GI:21322252	T20B12.2 - T06C12.13 T20B12.2 - F44G3.9 T20B12.2 - F16B4.9
KOG3575 - KOG4333	GI:7304901 - GMEB1 GI:6679695 - GMEB1	VDR - GMEB1	F44G3.9 - C25G4.4
KOG2996 - KOG4637	PI3K p85-alpha - Pik3r3 Vav - PI3K p85-alpha	DIP:1061N - PI3K p85-beta Vav2 - PI3K p85-beta Vav - Vav Proto-Oncogene Vav - PI3K p85-beta	C35B8.2 - Y110A7A.10
KOG2996 - KOG3575	PI3K p85-alpha - mSHP	p55alpha - GI:21322252	C35B8.2 - C08F8.8
KOG3575 - KOG3701	VDR - Smad3	DIP:158N - Smad2 PPARG - Smad2 RAR - Smad2 RAR - Smad8 RXR-alpha - Smad2 RXR-alpha - Smad3 RXR-alpha - SMAD4 RXR-alpha - Smad8 RARB - Smad2 RARB - SMAD4 RARB - Smad3 RARB - Smad8 ER-beta - SMAD4 ER-beta - SMAD7 ER-beta - Smad1 VDR - Smad3 VDR - SMAD4 VDR - Smad2 VDR - Smad1 PPAR-alpha - Smad2 GI:21322252 - SMAD4 GI:21322252 - Smad3 NR1H4 - Smad2 ER-alpha - Smad3 ER-alpha - Smad2 ER-alpha - SMAD4 ER-alpha - Smad8 ER-alpha - SMAD7 ER-alpha - Smad1 PPARD - Smad8 PPARD - Smad2	C08F8.8 - R13F6.9 C08F8.8 - sma-4 F44G3.9 - sma-4
KOG3544 - KOG3701	Type V Collagen - Smad2 Type V Collagen - Smad7 Type V Collagen - Smad3 Type III Collagen - Smad7 Type III Collagen - Smad3	COL4A2 - SMAD4 COL4A2 - Smad3 COL4A2 - Smad2 COL4A2 - Smad1 Collagen VII - Smad2	T05A1.2 - ZK370.2 F26F12.1 - sma-4 F14F7.1 - R13F6.9 W03G11.1 - sma-4 F23H12.4 - sma-4 T15B7.3 - sma-4
KOG0660 - KOG2996	Erk1 - PI3K p85-alpha Mapk1 - PI3K p85-alpha	ERK2 - Vav	B0218.3 - C35B8.2
KOG0660 - KOG3701	Mapk14 - Smad3	MAPK13 - SMAD4 MAPK13 - Smad5 MAPK13 - Smad3 MAPK13 - Smad2 MAPK13 - Smad1	B0218.3 - ZK370.2 B0218.3 - R13F6.9 MPK-1 - ZK370.2 MPK-1 - R13F6.9
KOG0603 - KOG0660	Rsk2 - Mapk1	Rsk3 - ERK2 RSK2 - Erk1	T01H8.1 - MPK-1
KOG0660 - KOG1703	Mapk14 - Cypher1 Erk1 - Paxillin Mapk1 - Paxillin	MAPK13 - ARA55	B0218.3 - C34B2.4 B0218.3 - EAT-1 MPK-1 - EAT-1 MPK-1 - C28H8.6 MPK-1 - Y65B4A.7
KOG0581 - KOG0660	erk2 - Mapk1 erk2 - Erk1 erk2 - Mapk14 MEK - Mapk1 MEK - Erk1	MKK5 - ERK5 MEK2 - ERK2 MEK2 - Erk1 MEK1 - ERK2 MEK1 - Erk1	MEK-2 - MPK-1

---

Conserved subnet 7:
13 conserved interactions between 14 ortholog groups.
This subnet exists in 4 organisms (p<6e-16).

Ortholog Groups
KOG2169	Zn-finger transcription factor
KOG2294	Transcription factor of the Forkhead/HNF3 family
KOG0653	Cyclin B and related kinase-activating proteins
KOG3484	Cyclin-dependent protein kinase CDC28, regulatory subunit CKS1, and related proteins
KOG1721	FOG: Zn-finger
KOG2330	Splicing factor 3b, subunit 2
KOG1973	Chromatin remodeling protein, contains PHD Zn-finger
KOG1342	Histone deacetylase complex, catalytic component RPD3
KOG1704	FOG: LIM domain
KOG0676	Actin and related proteins
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG0749	Mitochondrial ADP/ATP carrier proteins
KOG0841	Multifunctional chaperone (14-3-3 family)
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG2169 - KOG2294	PIAS1 - FoxO1 PIAS1 - FoxO3 PIAS1 - FoxO4	CG7958 - CG11799 DIP:18140N - CG11799	DIP:26255N - DAF-16	NFI1 - Fhl1
KOG0653 - KOG3484	Cyclin B1 - CKS1B cyclin B2 - CKS1B	DIP:17624N - CG9790 CycG - DIP:102N CycG - CG9790	DIP:24822N - C09G4.3 R02F2.1 - C09G4.3 H31G24.4 - C09G4.3	Clb3 - CKS1 Clb3 - DIP:102N Clb1 - CKS1 Clb1 - DIP:102N Clb6 - DIP:102N Clb6 - CKS1 Clb4 - CKS1 Clb4 - DIP:102N Cln1 - CKS1 Cln1 - DIP:102N Cln2 - CKS1 Cln2 - DIP:102N Clb2 - CKS1 Clb2 - DIP:102N Clb5 - CKS1 Clb5 - DIP:102N Cln3 - CKS1 Cln3 - DIP:102N
KOG1721 - KOG2330	PLZF - SF3b2 ZNF83 - SF3b2 PRDM4 - SF3b2 FLJ12586 - SF3b2 SIP1 - SF3b2 HIVEP1 - SF3b2 PLAGL1 - SF3b2 PLAG1 - SF3b2	odd - CG3605 bowl - CG3605 CG8159 - CG3605 D19A - CG3605 CG2116 - CG3605 CG10462 - CG3605 CG2889 - CG3605	F53B3.1 - W03F9.10 C27A12.2 - W03F9.10 F57C9.4 - W03F9.10	Swi5 - Cus1 MIG1 - Cus1 Nrg1p - Cus1
KOG1721 - KOG2294	PLZF - FoxO3 PLZF - FoxH1 PLZF - FoxO1 PLZF - FoxO4 ZNF83 - FoxO3 ZNF83 - FoxH1 ZNF83 - FoxO1 ZNF83 - FoxO4 PRDM4 - FoxO3 PRDM4 - FoxH1 PRDM4 - FoxO1 PRDM4 - FoxO4 FLJ12586 - FoxO3 FLJ12586 - FoxH1 FLJ12586 - FoxO1 FLJ12586 - FoxO4 SIP1 - FoxO3 SIP1 - FoxH1 SIP1 - FoxO1 SIP1 - FoxO4 HIVEP1 - FoxO3 HIVEP1 - FoxH1 HIVEP1 - FoxO1 HIVEP1 - FoxO4 PLAGL1 - FoxO3 PLAGL1 - FoxH1 PLAGL1 - FoxO1 PLAGL1 - FoxO4 PLAG1 - FoxO3 PLAG1 - FoxH1 PLAG1 - FoxO1 PLAG1 - FoxO4	opa - CG11799 opa - fd59A CG7752 - CG11799 Aef1 - foxo CG10654 - CG11799 D19B - jumu CG14451 - fd59A DIP:17332N - CG11799 DIP:17378N - fd59A GI:24653568 - CG11799 DIP:17897N - CG11799 CG6808 - fd59A CG15710 - fd64A CG10959 - CG11799 CG2129 - fd59A CG7987 - fd59A CG17801 - CG11799 CG11696 - fd64A CkIIalpha-i1 - fd64A l(2)35Ea - CG11799 CG2678 - fd59A CG9797 - fd59A CG9797 - CG11799 CG8301 - CG11799 CG8301 - fd59A Sry-beta - CG11799 CG1647 - fd64A CG4730 - CG11799 CG7928 - CG11799 CG7928 - fd59A CG7386 - fd59A CG10147 - jumu CG8145 - fd59A	F53B3.1 - T28H11.4	Swi5 - Fkh1 Swi5 - Fkh2p Swi5 - Hcm1p ADR1 - Fkh2p ADR1 - Hcm1 Yer028c - Hcm1 Fzf1 - Fkh1 MIG1 - Hcm1 Ygr067c - Hcm1 Ygr067c - Fkh2p RIM101 - Fkh1 Zap1 - Fkh1 Ace2 - Fkh1 Ace2 - Fkh2p Ace2 - Hcm1p
KOG1721 - KOG1973	IMAGE 3948563 - ING1L YY1 - p28ING5 YY1 - ING4 ZNF76 - ING1L SIP1 - ING1L Egr1 - p28ING5 Egr1 - ING4 KIAA0972 - ING1L	CG40145 - Bip2 opa - CG7379 CG10274 - CG7379 CG10267 - Bip2 CG17612 - Bip2 CG10543 - Bip2 MTF-1 - DIP:19186N MTF-1 - CG9293 CG4820 - CG6632 D19A - Bip2 D19A - CG7379 CG18476 - Bip2 su(Hw) - Bip2 DIP:19181N - DIP:19186N DIP:19181N - CG9293 CG10309 - Bip2 ken - Bip2 CG17568 - CG7379 CG10462 - Bip2 CG10462 - CG7379 EG:BACR42I17.11 - Bip2 CG2889 - Bip2 CG31365 - Bip2 CG4854 - Bip2 CG4936 - Bip2 Sry-delta - Bip2 CG7386 - Bip2 CG7386 - CG7379 CG10147 - Bip2 CG17806 - Bip2 CG11762 - Bip2 CG11798 - Bip2	EOR-1 - DIP:26104N	DIP:150N - Pho23 Swi5 - YNG2 ADR1 - Yng1 Ace2 - Yng1
KOG1342 - KOG1721	Rpd3p - YY1 Rpd3p - DIP:36N HDAC2 - YY1 HDAC2 - PLZF HDAC2 - Sp1 HDAC2 - DIP:36N HDAC1 - PLZF HDAC1 - DIP:5990N HDAC1 - Miz-1 HDAC1 - AEBP2 HDAC1 - Sp1 HDAC3 - BCL6 HDAC3 - zid HDAC3 - PLZF	dHDAC1 - pho dHDAC1 - Phol	C53A5.3 - F53B3.1	Hos2 - MIG1 Hos2 - Nrg1p Rpd3 - DIP:150N Rpd3 - Fzf1 Rpd3 - MIG1 Rpd3 - Nrg1p
KOG1704 - KOG1721	TES - ZNF510 PINCH-2 - ZFD25 FHL2 - ZNF36	Lmpt - sug Lmpt - CG7368 Lmpt - CG3032 Lmpt - CG17801 Lmpt - CG8145 stck - CG1832 stck - CG18262 stck - crol stck - CG10543 stck - CG11971 stck - D19B stck - CG8159 stck - odd stck - EG:95B7.7 stck - CG7386 stck - CG7928 stck - DIP:17378N stck - CG9797 stck - CG2116 stck - CG6808 stck - CG10267 stck - opa stck - CG14451 stck - CG33213 stck - CG7987 stck - CG12701 stck - CG18764 DIP:17600N - sug DIP:17600N - CG7368 DIP:17600N - CG3032 DIP:17600N - CG17801 DIP:17600N - CG8145 DIP:18649N - CG7357 DIP:18649N - CG11247 DIP:18649N - CG8159 Pax - CG11247 Pax - CG7357 Pax - CG8159 Lmpt - su(Hw) CG6522 - D19A CG6522 - CG11696 CG6522 - CG11695 CG6522 - su(Hw)	F28F5.3 - EOR-1 F28F5.3 - F54F2.5	RGA1 - Swi5 RGA1 - Ace2 Rga1 - ADR1 Rga1 - Swi5 Rga1 - Ace2
KOG0676 - KOG1721	ACTG1 - ZNF510 ACTG1 - HIVEP1 ACTG1 - zid ACTC - HIVEP1 ACTC - ZNF510	Arp87C - CG40145 Act87E - CG2678 Act87E - CG1647 Act87E - CG7386 Act87E - CG17801 Act87E - jing Act87E - CG7752 Act87E - CG7357 Act42A - CG33213 Act42A - sug Act42A - l(2)35Ea Act42A - opa Act42A - CG1792 Act42A - DIP:19658N Act42A - hkb Act42A - odd Act42A - CG8159 Act42A - CG17568 Act42A - CG18764 Arp11 - CG9797	T04C12.5 - F53B3.1 T04C12.5 - T09F3.1	actin - RIM101 actin - Swi5 ARP1 - Fzf1 ARP1 - Nrg2 Arp9p - Swi5
KOG0940 - KOG1721	NEDD4 - IMAGE 3948563 NEDD4 - SIP1 NEDD4 - KIAA0972 NEDD4 - ZNF76 KIAA1301 - IMAGE 3948563 KIAA1301 - SIP1 KIAA1301 - KIAA0972 KIAA1301 - ZNF76 FLJ32109 - SIP1 SMURF2 - ZFD25 SMURF2 - ZNF-U69274 SMURF2 - PLAG1 SMURF2 - HIVEP1 SMURF2 - SIP1 SMURF2 - ZNF83 SMURF2 - FLJ12586 SMURF2 - PLAGL1 SMURF2 - PRDM4 SMURF2 - PLZF SMURF2 - IMAGE 3948563 SMURF2 - KIAA0972 SMURF2 - ZNF76 SMURF1 - ZFD25 SMURF1 - ZNF-U69274 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76 SMURF1 - PLAG1 SMURF1 - HIVEP1 SMURF1 - SIP1 SMURF1 - ZNF83 SMURF1 - FLJ12586 SMURF1 - PLAGL1 SMURF1 - PRDM4 SMURF1 - PLZF SMURF1 - IMAGE 3948563 SMURF1 - KIAA0972 SMURF1 - ZNF76	CG7552 - DIP:17332N CG7552 - GI:24653568 CG7552 - CG8301 CG7552 - odd CG7552 - CG10267 CG3003 - CG7928 CG3003 - CG9793 CG3099 - DIP:17378N CG3099 - CG6808 CG3099 - CG8319 CG3099 - CG17568 CG3099 - CG2116 CG3099 - CG18476 CG3099 - DIP:19928N CG3099 - CG33213 CG3099 - CG7357 CG3099 - CG9797 CG3099 - CG8301 Nedd4 - CG9817 Nedd4 - CG1832 Nedd4 - CG18262 Nedd4 - crol Nedd4 - CG10543 Nedd4 - CG11971 Nedd4 - D19B Su(dx) - DIP:17332N Su(dx) - CG4820 Su(dx) - GI:24653568	Y65B4BR.4 - ZK867.1 Y65B4BR.4 - DIP:24379N Y65B4BR.4 - F54F2.5 Y65B4BR.4 - R08E3.4 Y65B4BR.4 - C27A12.2 Y65B4BR.4 - T09F3.1 Y65B4BR.4 - Y54E10BR.8 Y65B4BR.4 - ZK892.7 F13E6.4 - ZK867.1 F13E6.4 - DIP:24379N F13E6.4 - F54F2.5 F13E6.4 - R08E3.4 F13E6.4 - C27A12.2 F13E6.4 - T09F3.1 F13E6.4 - Y54E10BR.8	Rsp5 - Nrg2 Rsp5 - RIM101
KOG0749 - KOG1721	SLC25A5 - HIVEP1	DIP:19903N - pho Ant2 - CG18476 Ant2 - opa Ant2 - CG8301 Ant2 - DIP:17332N Ant2 - GI:24653568 Ant2 - CG7752 Ant2 - CG5245 Ant2 - CG8319 Ant2 - CG11247 Ant2 - CG10979	DIP:26442N - ZK867.1 DIP:26442N - DIP:24379N DIP:26442N - F54F2.5 DIP:26442N - R08E3.4 DIP:26442N - C27A12.2 DIP:26442N - T09F3.1 DIP:26442N - Y54E10BR.8 F25B4.7 - ZK867.1 F25B4.7 - DIP:24379N F25B4.7 - F54F2.5 F25B4.7 - R08E3.4 F25B4.7 - C27A12.2 F25B4.7 - T09F3.1 F25B4.7 - Y54E10BR.8 T27E9.1 - EOR-1	Pet9p - ADR1 AAC1 - Yer028c
KOG0841 - KOG1721	14-3-3-epsilon - BCL6 14-3-3-epsilon - PLZF 14-3-3tau - E4F1 14-3-3tau - ZF6 14-3-3tau - SIP1 14-3-3tau - ZNF83 14-3-3tau - FLJ20765	14-3-3-epsilon - CG10979 14-3-3-epsilon - CG9797 14-3-3-epsilon - CG6808 14-3-3-epsilon - CG2889 14-3-3-epsilon - CG10267 14-3-3-epsilon - DIP:22690N 14-3-3-epsilon - EP2237 14-3-3-epsilon - Aef1 14-3-3-epsilon - Sqz	PAR-5 - F47H4.1 PAR-5 - F54H5.4 ftt-2 - F53B3.1 F52D10.3 - F53B3.1	Bmh2 - ADR1 BMH1 - ADR1 BMH1 - Fzf1
KOG0581 - KOG1721	MEK2 - ZNF7 MEK1 - ZNF7	CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543	MEK-2 - F54F2.5	Pbs2 - ADR1 Mkk2 - ADR1 Mkk2 - Nrg2
KOG1721 - KOG3484	KLF6 - CKS1B	opa - CG9790 sug - DIP:102N sug - CG9790 Sqz - CG9790 zfh1 - CG9790	ZK892.7 - Y71G12B.27	Swi5 - DIP:102N Swi5 - CKS1 Ace2 - DIP:102N Ace2 - CKS1

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Conserved subnet 8:
10 conserved interactions between 6 ortholog groups.
This subnet exists in 3 organisms (p<6e-66).

Ortholog Groups
KOG0677	Actin-related protein Arp2/3 complex, subunit Arp2
KOG3380	Actin-related protein Arp2/3 complex, subunit ARPC5
KOG1876	Actin-related protein Arp2/3 complex, subunit ARPC4
KOG0678	Actin-related protein Arp2/3 complex, subunit Arp3
KOG2826	Actin-related protein Arp2/3 complex, subunit ARPC2
KOG1523	Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC

Conserved Interactions
Interaction	Bos taurus	Homo sapiens	Saccharomyces cerevisiae
KOG0677 - KOG3380	Actin-Like Protein 2 - Arp23 COMPLEX 16 KDA SUBUNIT	Arp2 - p16-Arc	ARP2 - ARC15
KOG1876 - KOG3380	Arp23 COMPLEX 20 KDA SUBUNIT - Arp23 COMPLEX 16 KDA SUBUNIT	p20 - p16-Arc	Arc19 - ARC15
KOG0678 - KOG2826	Actin-Like Protein 3 - Arp23 COMPLEX 34 KDA SUBUNIT	Arp3 - p34	ARP3 - ARC35
KOG0678 - KOG1876	Actin-Like Protein 3 - Arp23 COMPLEX 20 KDA SUBUNIT	Arp3 - p20	ARP3 - Arc19
KOG1876 - KOG2826	Arp23 COMPLEX 20 KDA SUBUNIT - Arp23 COMPLEX 34 KDA SUBUNIT	p20 - p34	Arc19 - ARC35
KOG0677 - KOG1523	Actin-Like Protein 2 - Arp23 COMPLEX 41 KDA SUBUNIT	Arp2 - p41	ARP2 - Arc40
KOG1523 - KOG3380	Arp23 COMPLEX 41 KDA SUBUNIT - Arp23 COMPLEX 16 KDA SUBUNIT	p41 - p16-Arc	Arc40 - ARC15
KOG1523 - KOG2826	Arp23 COMPLEX 41 KDA SUBUNIT - Arp23 COMPLEX 34 KDA SUBUNIT	p41 - p34	Arc40 - ARC35
KOG1523 - KOG1876	Arp23 COMPLEX 41 KDA SUBUNIT - Arp23 COMPLEX 20 KDA SUBUNIT	p41 - p20	Arc40 - Arc19
KOG0678 - KOG1523	Actin-Like Protein 3 - Arp23 COMPLEX 41 KDA SUBUNIT	Arp3 - p41	ARP3 - Arc40

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Conserved subnet 9:
9 conserved interactions between 6 ortholog groups.
This subnet exists in 3 organisms (p<1e-78).

Ortholog Groups
KOG1656	Protein involved in glucose derepression and pre-vacuolar endosome protein sorting
KOG3229	Vacuolar sorting protein VPS24
KOG2760	Vacuolar sorting protein VPS36
KOG4068	Uncharacterized conserved protein
KOG3341	RNA polymerase II transcription factor complex subunit
KOG2910	Uncharacterized conserved protein predicted to be involved in protein sorting

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1656 - KOG3229	CHMP4B - CHMP3 CHMP4C - CHMP3	CG8055 - CG9779	Vps32 - Vps24
KOG1656 - KOG1656	CHMP4A - CHMP4B CHMP4A - CHMP4B CHMP4A - CHMP4C CHMP4B - CHMP4C CHMP4B - CHMP4B CHMP4B - CHMP4A CHMP4C - CHMP4B CHMP4C - CHMP4C CHMP4C - CHMP4B CHMP4C - CHMP4A CHMP4B - CHMP4C CHMP4B - CHMP4B CHMP4B - CHMP4A	CG8055 - CG8055	Vps32 - Vps32
KOG2760 - KOG4068	EAP45 - EAP20	CG10711 - CG14750	Vps36 - Vps25
KOG2760 - KOG3341	EAP45 - EAP30	CG10711 - CG6637	Vps36 - Vps22
KOG3341 - KOG4068	EAP30 - EAP20	CG6637 - CG14750	Vps22 - Vps25
KOG2760 - KOG2910	EAP45 - CHMP6	CG10711 - CG4071	Vps36 - Vps20
KOG2910 - KOG3341	CHMP6 - EAP30	CG4071 - CG6637	Vps20 - Vps22
KOG2910 - KOG4068	CHMP6 - EAP20	CG4071 - CG14750	Vps20 - Vps25
KOG1656 - KOG2910	CHMP4C - CHMP6 CHMP4B - CHMP6	CG8055 - CG4071	Vps32 - Vps20

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Conserved subnet 10:
9 conserved interactions between 7 ortholog groups.
This subnet exists in 3 organisms (p<1e-47).

Ortholog Groups
KOG3302	TATA-box binding protein (TBP), component of TFIID and TFIIIB
HG1793	Homologene family 1793
KOG1744	Histone H2B
KOG2393	Transcription initiation factor IIF, large subunit (RAP74)
KOG3334	Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)
KOG2549	Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA)
KOG1142	Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA)

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG3302 - HG1793	TBP - MDM2 DIP:24197N - MDM2 DIP:1078N - MDM2	TBP - HDM2	TBP1 - DIP:24196N
KOG1744 - KOG3302	DIP:421N - DIP:1078N	DIP:421N - TBP	Htb2 - TBP1
KOG2393 - KOG3302	DIP:677N - DIP:1078N	GTF2F1 - TBP	Tfg1 - TBP1
KOG3302 - KOG3334	DIP:1078N - DIP:435N	TBP - TAF9	DIP:1078N - TAF17 TBP1 - TAF17
KOG2549 - KOG3334	DIP:493N - DIP:435N	DIP:493N - TAF9 DIP:773N - TAF9 DIP:773N - DIP:239N TAF6 - TAF9	Taf6 - TAF17
KOG2549 - KOG3302	DIP:493N - DIP:1078N	DIP:493N - TBP	Taf6 - TBP1 Taf6 - DIP:1078N Taf6 - DIP:80N
KOG1142 - KOG3302	DIP:496N - DIP:1078N	TAF12 - TBP	TAF61 - TBP1 TAF61 - DIP:1078N
KOG1142 - KOG2549	DIP:496N - DIP:493N	TAF12 - DIP:493N	TAF61 - Taf6
KOG1142 - KOG3334	DIP:496N - DIP:435N	TAF12 - TAF9	TAF61 - TAF17

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Conserved subnet 11:
8 conserved interactions between 8 ortholog groups.
This subnet exists in 3 organisms (p<2e-16).

Ortholog Groups
KOG0594	Protein kinase PCTAIRE and related kinases
KOG3575	FOG: Hormone receptors
KOG2330	Splicing factor 3b, subunit 2
KOG0619	FOG: Leucine rich repeat
KOG0985	Vesicle coat protein clathrin, heavy chain
KOG1721	FOG: Zn-finger
KOG0603	Ribosomal protein S6 kinase
KOG4333	Nuclear DEAF-1 related transcriptional regulator (suppressin) and related SAND domain proteins

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG0594 - KOG3575	CDK4 - GI:6679695 CDK4 - GI:7304901	CG30171 - ftz-f1	T05G5.3 - C08F8.8
KOG3575 - KOG3575	RXRA - RXRA GI:7304901 - GI:6679695 GI:6679695 - GI:7304901 Esrrg - Esrrg	DIP:18899N - ftz-f1 Hr39 - tll ftz-f1 - DIP:18899N tll - Hr39 USP - USP	F58G6.5 - nhr-34 nhr-2 - C08F8.8 nhr-2 - F43C1.4 nhr-61 - nhr-4 C08F8.8 - nhr-2 C08F8.8 - F44G3.9 Y45G5AM.1 - F44G3.9 Y45G5AM.1 - R04B5.4 nhr-34 - F58G6.5 nhr-1 - R09G11.2 nhr-4 - nhr-61 nhr-4 - C26B2.3 Y80D3A.4 - C27C7.4 Y80D3A.4 - nhr-71 Y80D3A.4 - nhr-13 Y80D3A.4 - Y38E10A.18 Y80D3A.4 - NHR-22 Y80D3A.4 - ZK1037.5 Y80D3A.4 - ZK697.2 C26B2.3 - R04B5.4 C26B2.3 - nhr-13 C26B2.3 - F44G3.9 C26B2.3 - nhr-4 ZK697.2 - C27C7.4 ZK697.2 - nhr-71 ZK697.2 - nhr-13 ZK697.2 - Y38E10A.18 ZK697.2 - NHR-22 ZK697.2 - ZK1037.5 ZK697.2 - Y80D3A.4 ZK1037.5 - C27C7.4 ZK1037.5 - nhr-71 ZK1037.5 - nhr-13 ZK1037.5 - Y38E10A.18 ZK1037.5 - NHR-22 ZK1037.5 - ZK697.2 ZK1037.5 - Y80D3A.4 NHR-22 - C27C7.4 NHR-22 - nhr-71 NHR-22 - nhr-13 NHR-22 - Y38E10A.18 NHR-22 - ZK1037.5 NHR-22 - ZK697.2 NHR-22 - Y80D3A.4 NHR-22 - R04B5.4 C45E5.6 - F44G3.9 nhr-13 - C27C7.4 nhr-13 - nhr-71 nhr-13 - Y38E10A.18 nhr-13 - NHR-22 nhr-13 - ZK1037.5 nhr-13 - ZK697.2 nhr-13 - Y80D3A.4 nhr-13 - R04B5.4 nhr-13 - F44G3.9 nhr-13 - C26B2.3 F16B4.9 - T06C12.13 F16B4.9 - F44G3.9 nhr-71 - C27C7.4 nhr-71 - nhr-13 nhr-71 - Y38E10A.18 nhr-71 - NHR-22 nhr-71 - ZK1037.5 nhr-71 - ZK697.2 nhr-71 - Y80D3A.4 Y38E10A.18 - C27C7.4 Y38E10A.18 - nhr-71 Y38E10A.18 - nhr-13 Y38E10A.18 - NHR-22 Y38E10A.18 - ZK1037.5 Y38E10A.18 - ZK697.2 Y38E10A.18 - Y80D3A.4 F44G3.9 - F44G3.9 F44G3.9 - T06C12.13 F44G3.9 - F16B4.9 F44G3.9 - R04B5.4 F44G3.9 - nhr-13 F44G3.9 - C26B2.3 F44G3.9 - Y45G5AM.1 F44G3.9 - C45E5.6 F44G3.9 - C08F8.8 F44G3.9 - B0280.8 C11G6.4 - C33G8.6 F43C1.4 - nhr-2 R09G11.2 - nhr-1 B0280.8 - B0280.8 B0280.8 - F44G3.9 R04B5.4 - Y45G5AM.1 R04B5.4 - NHR-22 R04B5.4 - nhr-13 R04B5.4 - F44G3.9 R04B5.4 - C26B2.3 C33G8.6 - C11G6.4 C27C7.4 - nhr-71 C27C7.4 - nhr-13 C27C7.4 - Y38E10A.18 C27C7.4 - NHR-22 C27C7.4 - ZK1037.5 C27C7.4 - ZK697.2 C27C7.4 - Y80D3A.4 T06C12.13 - F44G3.9 T06C12.13 - F16B4.9
KOG2330 - KOG3575	SF3b2 - VDR	CG3605 - tll	W03F9.10 - F44G3.9 W03F9.10 - Y45G5AM.1
KOG0619 - KOG3575	Erbin - VDR	Sur-8 - ftz-f1 wdp - ftz-f1 sli - ftz-f1	F33G12.4 - nhr-4 F33G12.4 - C26B2.3 SUR-8 - C08F8.8
KOG0985 - KOG3575	Clathrin - mSHP	Chc - ftz-f1	T20G5.1 - F44G3.9 T20G5.1 - nhr-4 T20G5.1 - C26B2.3
KOG1721 - KOG3575	ZAC1 - DIP:125N ZAC1 - GI:6679695 ZAC1 - GI:7304901 BCL-6 - PPAR-delta	opa - Hr39 opa - DIP:18899N opa - ftz-f1 CG10274 - ftz-f1 CG10274 - DIP:18899N CG7752 - ftz-f1 D19A - svp D19A - tll su(Hw) - svp CG7987 - DIP:18899N CG7987 - ftz-f1 CG17801 - Hr96 GI:17647565 - tll DIP:19928N - DIP:18899N CG10348 - ftz-f1 CG10348 - Hr96 CG10348 - DIP:18899N CG10348 - tll CG17568 - DIP:18899N CG17568 - ftz-f1 CG9609 - svp l(2)35Ea - DIP:18899N l(2)35Ea - ftz-f1 jing - ftz-f1 sug - DIP:18899N sug - tll sug - ftz-f1 CG1647 - Hr96 CG4730 - ftz-f1 CG4730 - DIP:18899N CG7386 - Hr96 CG10147 - svp CG8145 - Hr96 CG8145 - Hr39 CG11762 - Hr39	DIP:24379N - Y15E3A.1 DIP:24379N - R04B5.4 DIP:24379N - nhr-13 DIP:24379N - F44G3.9 DIP:24379N - C26B2.3 EOR-1 - F44G3.9 EOR-1 - C45E5.6 Y54E10BR.8 - R04B5.4 Y54E10BR.8 - nhr-13 Y54E10BR.8 - F44G3.9 Y54E10BR.8 - C26B2.3 F54H5.4 - F44C8.11 F54H5.4 - nhr-2 T09F3.1 - R04B5.4 T09F3.1 - nhr-13 T09F3.1 - F44G3.9 T09F3.1 - C26B2.3 T22C8.3 - F44G3.9 F53B3.1 - F44G3.9 F53B3.1 - Y45G5AM.1 C07A12.1 - Y15E3A.1 C07A12.1 - R04B5.4 C07A12.1 - Y45G5AM.1 C07A12.1 - nhr-13 F47H4.1 - nhr-2 C27A12.2 - F44G3.9 C27A12.2 - Y45G5AM.1 C27A12.2 - R04B5.4 C27A12.2 - nhr-13 C27A12.2 - C26B2.3 R08E3.4 - R04B5.4 R08E3.4 - nhr-13 R08E3.4 - F44G3.9 R08E3.4 - C26B2.3 F54F2.5 - F44G3.9 F54F2.5 - R04B5.4 F54F2.5 - nhr-13 F54F2.5 - C26B2.3 ZK892.7 - F44G3.9 ZK867.1 - Y15E3A.1 ZK867.1 - F44G3.9 ZK867.1 - R04B5.4 ZK867.1 - nhr-13 ZK867.1 - C26B2.3 F57C9.4 - F44G3.9 F57C9.4 - Y45G5AM.1 C46E10.9 - C26B2.3
KOG0603 - KOG1721	p90RSK - KLF5	Pk61C - CG7386 Pk61C - CG10979 DIP:20399N - CG10462 DIP:20399N - CG7386 DIP:20399N - CG10979 CG30171 - jing CG30171 - CG7752 CG30171 - CG1832 CG30171 - CG18262 CG30171 - crol CG30171 - CG10543 CG30171 - CG11971 CG30171 - D19B CG30171 - EG:BACR42I17.11 CG30171 - Sry-delta CG30171 - CG10147 CG30171 - CG11798 CG30171 - CG4936 CG30171 - CG10309 CG30171 - su(Hw) CG30171 - CG18476 CG30171 - D19A CG30171 - CG10543 S6kII - CG11798 S6kII - CG2116 S6kII - CG7987 S6kII - GI:24653568 S6kII - DIP:17332N	E01H11.1 - F53B3.1
KOG1721 - KOG4333	ZAC1 - GMEB1	wdn - Deaf1 CG10979 - Deaf1 CG11247 - Deaf1 CG8159 - Deaf1 DIP:17378N - Deaf1 CG10959 - Deaf1 CG17801 - Deaf1 EG:95B7.7 - Deaf1 CG18011 - Deaf1 CG3281 - Deaf1 CG7357 - Deaf1	T09F3.1 - C25G4.4 F53B3.1 - C25G4.4

---

Conserved subnet 12:
7 conserved interactions between 6 ortholog groups.
This subnet exists in 3 organisms (p<1e-43).

Ortholog Groups
HG924	Homologene family 924
HG7242	Homologene family 7242
KOG4728	Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel
HG7413	Homologene family 7413
KOG0841	Multifunctional chaperone (14-3-3 family)
HG3189	Homologene family 3189

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
HG924 - HG7242	Biklk - Bax	Biklk - Bax	Bik - Bax Bik - DIP:231N
KOG4728 - HG924	Bcl2a1 - Biklk Bak1 - Biklk Bcl-w - Biklk	Bcl-2 - Biklk	Bcl-xL - Bik Bcl-2 - Bik Bak - Bik GI:4757840 - Bik Bcl-w - Bik
KOG4728 - HG7413	Bcl2a1 - Mcl1 Bak1 - Mcl1 Bcl-w - Mcl1 Bcl2 - Mcl1 Bcl2l1 - Mcl1	Bcl-w - Mcl-1 Bcl-2 - Mcl-1	Bcl-xL - DIP:231N Bcl-2 - DIP:231N Bak - DIP:231N
KOG0841 - KOG4728	Ywhaq - Bcl-w	14-3-3-tau - Bcl-2 14-3-3-tau - Bcl-w 14-3-3-tau - DIP:328N	14-3-3-beta - Bcl-2 14-3-3-zeta - Bcl-2 14-3-3tau - Bcl-2
KOG4728 - HG7242	Bcl2a1 - Bax Bak1 - Bax Bcl-w - Bax Bcl2 - Bax	Bcl-2 - Bax	Bcl-xL - Bax Bcl-xL - DIP:231N Bcl-2 - DIP:231N Bcl-2 - Bax Bcl-2 - Bax Bak - Bax Bak - DIP:231N GI:4757840 - Bax Bcl-w - Bax
HG3189 - HG7242	Bad-alpha - Bax	BAD - Bax	DIP:273N - Bax DIP:273N - DIP:231N Bad - DIP:231N Bad - Bax
KOG4728 - HG3189	Bcl2a1 - Bad-alpha Bak1 - Bad-alpha Bcl-w - Bad-beta Bcl-w - Bad-alpha	DIP:328N - BAD Bcl-w - BAD Bcl-2 - BAD	Bcl-xL - Bad Bcl-xL - DIP:273N Bcl-2 - Bad Bcl-2 - DIP:273N Bak - Bad Bak - DIP:273N Bcl-Xs - Bad GI:4757840 - Bad Bcl-w - Bad

---

Conserved subnet 13:
7 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<3e-49).

Ortholog Groups
KOG3302	TATA-box binding protein (TBP), component of TFIID and TFIIIB
HG460	Homologene family 460
KOG3334	Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)
KOG2549	Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA)
KOG1142	Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA)

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG3302 - HG460	TBP - p53 DIP:24197N - p53 DIP:1078N - p53	TBP - TP53	Tbp - p53
KOG3302 - KOG3334	DIP:1078N - DIP:435N	TBP - TAF9	Tbp - DIP:239N
KOG2549 - KOG3334	DIP:493N - DIP:435N	DIP:493N - TAF9 DIP:773N - TAF9 DIP:773N - DIP:239N TAF6 - TAF9	DIP:772N - DIP:239N DIP:778N - DIP:239N Taf6 - e(y)1
KOG2549 - KOG3302	DIP:493N - DIP:1078N	DIP:493N - TBP	DIP:778N - Tbp
KOG1142 - KOG3302	DIP:496N - DIP:1078N	TAF12 - TBP	Taf12 - Tbp
KOG1142 - KOG2549	DIP:496N - DIP:493N	TAF12 - DIP:493N	Taf12 - DIP:778N
KOG1142 - KOG3334	DIP:496N - DIP:435N	TAF12 - TAF9	Taf12 - DIP:239N

---

Conserved subnet 14:
6 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<8e-37).

Ortholog Groups
HG180	Homologene family 180
HG32049	Homologene family 32049
HG32064	Homologene family 32064
HG2971	Homologene family 2971
HG12734	Homologene family 12734

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
HG180 - HG180	Jag1 - DIP:6008N DIP:6008N - Jag1	Factor Ix - Factor Ix	DIP:17770N - CG7447 CG7447 - DIP:17770N
HG32049 - HG32049	DLK1 - DLK1	Factor Ix - Factor Ix	CG12908 - Notch CG12908 - GI:24584298 DIP:17770N - CG7447 DIP:17770N - Notch CG7447 - DIP:17770N trol - sli trol - Notch Notch - CG12908 Notch - trol Notch - DIP:17770N GI:24584298 - CG12908 sli - trol
HG180 - HG32049	Jag1 - DLK1 DIP:6008N - DLK1	Factor Ix - Factor Ix	DIP:214N - Notch CG12908 - Notch CG12908 - GI:24584298 DIP:17770N - CG7447 DIP:17770N - Notch CG7447 - DIP:17770N trol - sli trol - Notch
HG32049 - HG32064	Notch1 - p65	DIP:27583N - NF-kappa-B	DIP:17770N - GI:24584826 CG7447 - GI:24584826
HG2971 - HG32064	p50 - p65	p50 - NF-kappa-B DIP:27583N - NF-kappa-B	CG17419 - GI:24584826
HG12734 - HG32064	I-kappa-B-zeta - p65	DIP:27583N - NF-kappa-B	CG17419 - GI:24584826

---

Conserved subnet 15:
6 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<1e-36).

Ortholog Groups
KOG1636	DNA polymerase delta processivity factor (proliferating cell nuclear antigen)
KOG0989	Replication factor C, subunit RFC4
KOG1970	Checkpoint RAD17-RFC complex, RAD17/RAD24 component
KOG2035	Replication factor C, subunit RFC3

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1636 - KOG1636	PCNA - PCNA	W03D2.4 - W03D2.4	Pol30 - Pol30 Pol30 - POL30 POL30 - Pol30
KOG0989 - KOG1970	RFC37 - Rad17p	F31E3.3 - F32A11.2	Rfc2 - Rad24
KOG0989 - KOG1636	RFC37 - PCNA	F31E3.3 - W03D2.4	Rfc2 - Pol30 Rfc2 - POL30
KOG0989 - KOG2035	RFC37 - RFC3	F31E3.3 - C39E9.13	Rfc2 - Rfc5
KOG1636 - KOG2035	PCNA - RFC3	W03D2.4 - C39E9.13	Pol30 - Rfc5 POL30 - Rfc5
KOG1970 - KOG2035	Rad17p - RFC3	F32A11.2 - C39E9.13	Rad24 - Rfc5

---

Conserved subnet 16:
6 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<2e-23).

Ortholog Groups
KOG0810	SNARE protein Syntaxin 1 and related proteins
KOG0860	Synaptobrevin/VAMP-like protein
KOG1586	Protein required for fusion of vesicles in vesicular transport, alpha-SNAP
KOG3065	SNAP-25 (synaptosome-associated protein) component of SNARE complex

Conserved Interactions
Interaction	Rattus norvegicus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0810 - KOG0860	syntaxin III - Synaptobrevin 2 syntaxin IV - Synaptobrevin 2 Syntaxin 1A - Synaptobrevin 2 syntaxin II - Synaptobrevin 2	Syx1A - Syb	SSO2 - SNC1 SSO2 - SNC2 Sso1 - SNC2 Sso1 - SNC1
KOG0810 - KOG1586	Syntaxin 1A - alpha-SNAP	Syx1A - Snap	SSO2 - Sec17 Sso1 - Sec17
KOG0810 - KOG3065	syntaxin III - Snap-25B[1-83] syntaxin IV - Snap-25B[1-83] Syntaxin 1A - Snap-25B[1-83] syntaxin II - Snap-25B[1-83]	Syx1A - usnp Syx1A - Snap24	SSO2 - Sec9 Sso1 - Spo20 Sso1 - Sec9
KOG1586 - KOG3065	alpha-SNAP - Snap-25B[1-83]	Snap - usnp	Sec17 - Sec9 Sec17 - Spo20
KOG0860 - KOG3065	Synaptobrevin 2 - Snap-25B[1-83]	Syb - Snap24 Syb - usnp	Nyv1p - Sec9 SNC2 - Spo20 SNC2 - Sec9 SNC1 - Sec9
KOG0860 - KOG1586	Synaptobrevin 2 - alpha-SNAP	Syb - Snap	Nyv1p - Sec17 SNC2 - Sec17 NYV1 - Sec17 SNC1 - Sec17

---

Conserved subnet 17:
5 conserved interactions between 6 ortholog groups.
This subnet exists in 3 organisms (p<5e-20).

Ortholog Groups
KOG1053	Glutamate-gated NMDA-type ion channel receptor subunit GRIN2A and related subunits
HG12938	Homologene family 12938
KOG3528	FOG: PDZ domain
KOG3209	WW domain-containing protein
KOG3550	Receptor targeting protein Lin-7
KOG0708	Membrane-associated guanylate kinase MAGUK (contains PDZ, SH3, HOOK and GUK domains)

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG1053 - HG12938	NR2B - PSD-95	NR2A - CIPP NR2B - CIPP	NMDA receptor 2B - MAGI3
KOG1053 - KOG3528	NR2B - PSD-95	NR2A - CIPP NR2B - CIPP	NMDA receptor 2B - MAGI3
KOG1053 - KOG3209	NR2B - PSD-95	NR2A - CIPP NR2B - CIPP	NMDA receptor 2B - MAGI3
KOG1053 - KOG3550	NR2B - PSD-95	NR2A - CIPP NR2B - CIPP	NMDA receptor 2B - MAGI3
KOG0708 - KOG3550	Dlgh1 - Veli-3 Dlgh1 - PSD-95 Dlgh2 - PSD-95	Dlgh1 - Lin-7 PSD-95 - CIPP DLG2 - CIPP DLG2 - Lin-7	MAGI-1B - LIN-7B PSD-95 - MAGI-1B PSD-95 - LIN-7B

---

Conserved subnet 18:
5 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<1e-16).

Ortholog Groups
KOG0583	Serine/threonine protein kinase
KOG1947	Leucine rich repeat proteins, some proteins contain F-box
KOG1724	SCF ubiquitin ligase, Skp1 component
KOG2166	Cullins
KOG2930	SCF ubiquitin ligase, Rbx1 component

Conserved Interactions
Interaction	Homo sapiens	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0583 - KOG0583	LKB1 - AMPK-alpha LKB1 - LKB1 AMPK-alpha - LKB1	Tpk1p - Tpk1p Snf1 - Kin2 Kcc4 - Ypl141c Kcc4 - Ypl150w Ksp1p - Kin2 Kin2 - Ksp1p Kin2 - Snf1 Kin2 - Ptk2p Ypl150w - Kcc4 Ypl141c - Kcc4 Ptk2p - Kin2	PKS3 - PKS3
KOG0583 - KOG1947	STK22D - FBXL12	Snf1 - Grr1 Snf1 - RAD7 Kin2 - Grr1 Ptk2p - Grr1	ASK1 - SKIP18 ASK1 - SKIP19
KOG1724 - KOG2166	SKP1A - Cul1 [15-410]	Skp1 - Cdc53 Skp1 - RTT101 Skp1 - CUL3	ASK2 - CUL1 ASK2 - AtCUL1 ASK3 - CUL1 ASK11 - CUL1 ASK11 - AtCUL1 ASK12 - CUL1 ASK4 - CUL1 ASK1 - CUL1 ASK1 - AtCUL1 ASK9 - CUL1 ASK9 - AtCUL1 ASK19 - CUL1 ASK14 - CUL1
KOG2166 - KOG2930	Cul1 [15-410] - RBX1	Cdc53 - HRT1 CUL3 - HRT1 RTT101 - HRT1	CUL1 - RBX1
KOG1947 - KOG2166	Fbl3a - Cul1 [15-410]	Grr1 - Cdc53 Grr1 - RTT101 Grr1 - CUL3	TIR1 - AtCUL1 SKIP19 - CUL1 SKIP18 - CUL1

---

Conserved subnet 19:
5 conserved interactions between 6 ortholog groups.
This subnet exists in 3 organisms (p<1e-07).

Ortholog Groups
KOG1217	Fibrillins and related proteins containing Ca2+-binding EGF-like domains
KOG1218	Proteins containing Ca2+-binding EGF-like domains
KOG1215	Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains
KOG1226	Integrin beta subunit (N-terminal portion of extracellular region)
KOG3743	Recombination signal binding protein-J kappa(CBF1, Su(H), HS2NF5)
KOG3528	FOG: PDZ domain

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG1217 - KOG1218	DIP:5N - DIP:214N Fibulin-2 - Perlecan DLK1 - DLK1 DIP:6008N - DLK1	DIP:24016N - CG7526 CG12908 - GI:24584298 SP1070 - trol DIP:17770N - BG:DS00180.10 DIP:17770N - BG:DS00180.8 DIP:17770N - BG:DS00180.14 CG7447 - BG:DS00180.10 CG7447 - BG:DS00180.8 DIP:18444N - BG:DS00180.10 BG:DS00180.8 - BG:DS00180.10 BG:DS00180.8 - BG:DS00180.14 CG31999 - BG:DS00180.10 CG31999 - BG:DS00180.8 CG31999 - BG:DS00180.14 trol - sli GI:24584298 - CG12908 GI:24648166 - BG:DS00180.10 BG:DS00180.10 - BG:DS00180.8 BG:DS00180.10 - BG:DS00180.14 C901 - BG:DS00180.10 C901 - BG:DS00180.8 C901 - BG:DS00180.14 CG5639 - trol CG9572 - BG:DS00180.10 CG9572 - trol CG9572 - BG:DS00180.8 CG9572 - BG:DS00180.14 sli - trol	DIP:24487N - F48E3.8 F48E3.8 - DIP:24487N Y69H2.3A - Y64G10A.7 F58E6.3 - Y64G10A.7 R02F11.1 - Y64G10A.7
KOG1215 - KOG1217	DIP:5N - DIP:214N DIP:214N - DIP:5N Perlecan - Fibulin-2 DIP:6008N - DLK1	CG7526 - DIP:24016N CG12908 - GI:24584298 DIP:17306N - DIP:17770N DIP:18444N - BG:DS00180.10 DIP:18444N - DIP:17770N DIP:18444N - CG9572 DIP:18444N - C901 trol - sli trol - CG9572 trol - CG5639 trol - SP1070 CG12139 - trol CG12139 - sli CG8909 - trol CG8909 - CG9572	T21E3.3 - K07D8.1 T21E3.3 - K08E5.3 T04H1.6 - R02F11.1 T04H1.6 - T06E6.10
KOG1217 - KOG1226	DIP:5N - DIP:214N DIP:214N - DIP:5N DLK1 - DIP:6008N	trol - mys	K08E5.3 - ZK1058.2 K07D8.1 - ZK1058.2
KOG1217 - KOG3743	DIP:214N - DIP:177N	DIP:214N - Su(H) CG12908 - Su(H) BG:DS00180.10 - Su(H)	Y69H2.3A - LAG-1 GLP-1 - LAG-1
KOG1217 - KOG3528	Delta1 - MUPP1	DIP:17770N - X11L DIP:17770N - INAD DIP:17770N - CG14168 DIP:17770N - Patj DIP:18444N - CG6688 DIP:18444N - INAD BG:DS00180.8 - CG6619 BG:DS00180.8 - DIP:18367N CG31999 - DIP:18367N CG31999 - scrib trol - X11L GI:24584298 - CG6619 GI:24648166 - scrib BG:DS00180.10 - CG6619 BG:DS00180.10 - CG14168 BG:DS00180.10 - X11L Crb - Dlt Crb - Bazooka Crb - Patj CG9572 - DIP:18367N	FBL-1 - ZK849.2 FBL-1 - F30F8.3 fbl-1 - DIP:26387N fbl-1 - F30F8.3 Y69H2.3A - ZK849.2 F58E6.3 - ZK849.2 F58E6.3 - DIP:26387N R02F11.1 - ZK849.2 R02F11.1 - DIP:26387N T06E6.10 - DIP:26387N T06E6.10 - ZK849.2

---

Conserved subnet 20:
5 conserved interactions between 4 ortholog groups.
This subnet exists in 4 organisms (p<8e-44).

Ortholog Groups
KOG2549	Transcription initiation factor TFIID, subunit TAF6 (also component of histone acetyltransferase SAGA)
KOG3334	Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA)
KOG3302	TATA-box binding protein (TBP), component of TFIID and TFIIIB
KOG1142	Transcription initiation factor TFIID, subunit TAF12 (also component of histone acetyltransferase SAGA)

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2549 - KOG3334	DIP:493N - DIP:435N	DIP:493N - TAF9 DIP:773N - TAF9 DIP:773N - DIP:239N TAF6 - TAF9	DIP:772N - DIP:239N DIP:778N - DIP:239N Taf6 - e(y)1	Taf6 - TAF17
KOG2549 - KOG3302	DIP:493N - DIP:1078N	DIP:493N - TBP	DIP:778N - Tbp	Taf6 - TBP1 Taf6 - DIP:1078N Taf6 - DIP:80N
KOG3302 - KOG3334	DIP:1078N - DIP:435N	TBP - TAF9	Tbp - DIP:239N	DIP:1078N - TAF17 TBP1 - TAF17
KOG1142 - KOG3302	DIP:496N - DIP:1078N	TAF12 - TBP	Taf12 - Tbp	TAF61 - TBP1 TAF61 - DIP:1078N
KOG1142 - KOG3334	DIP:496N - DIP:435N	TAF12 - TAF9	Taf12 - DIP:239N	TAF61 - TAF17

---

Conserved subnet 21:
5 conserved interactions between 6 ortholog groups.
This subnet exists in 3 organisms (p<2e-43).

Ortholog Groups
KOG1782	Small Nuclear ribonucleoprotein splicing factor
KOG3448	Predicted snRNP core protein
KOG3482	Small nuclear ribonucleoprotein (snRNP) SMF
KOG1781	Small Nuclear ribonucleoprotein splicing factor
KOG3293	Small nuclear ribonucleoprotein (snRNP)
KOG3459	Small nuclear ribonucleoprotein (snRNP) Sm core protein

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1782 - KOG3448	CG4279 - CG10418	F40F8.9 - T10G3.6	LSM1 - Lsm2
KOG3448 - KOG3482	CG10418 - DebB	T10G3.6 - ZK652.1	Lsm2 - SMX3
KOG1781 - KOG3293	CG13277 - DIP:21162N CG13277 - CG31990	ZK593.7 - F32A5.7	LSM7 - LSM4
KOG1781 - KOG3459	CG13277 - CG1249	ZK593.7 - C52E4.3	LSM7 - Smd2
KOG3459 - KOG3482	CG1249 - DebB	C52E4.3 - ZK652.1	Smd2 - SMX3

---

Conserved subnet 22:
4 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<2e-19).

Ortholog Groups
KOG1300	Vesicle trafficking protein Sec1
KOG1983	Tomosyn and related SNARE-interacting proteins
KOG0810	SNARE protein Syntaxin 1 and related proteins
KOG0860	Synaptobrevin/VAMP-like protein

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Saccharomyces cerevisiae
KOG1300 - KOG1983	Munc-18-2 - M-Tomosyn Isoform Munc-18 - M-Tomosyn Isoform	Stxbp3 - Mlg1	SEC1 - Sro7 SEC1 - Sro77
KOG0810 - KOG1300	syntaxin III - Munc-18 syntaxin III - Munc-18-2 Syntaxin 1A - Munc-18 Syntaxin 1A - Munc-18-2 syntaxin II - Munc-18 syntaxin II - Munc-18-2	syntaxin 4 - Stxbp3	SSO2 - SEC1 Sso1 - SEC1
KOG0860 - KOG1300	Synaptobrevin 2 - Munc-18 Synaptobrevin 2 - Munc-18-2	VAMP2 - Stxbp3	SNC2 - SEC1 SNC1 - SEC1
KOG0810 - KOG0860	syntaxin III - Synaptobrevin 2 syntaxin IV - Synaptobrevin 2 Syntaxin 1A - Synaptobrevin 2 syntaxin II - Synaptobrevin 2	syntaxin 4 - VAMP2	SSO2 - SNC1 SSO2 - SNC2 Sso1 - SNC2 Sso1 - SNC1

---

Conserved subnet 23:
4 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<2e-07).

Ortholog Groups
KOG1217	Fibrillins and related proteins containing Ca2+-binding EGF-like domains
KOG3510	FOG: Immunoglobulin C-2 Type/fibronectin type III domains
KOG0708	Membrane-associated guanylate kinase MAGUK (contains PDZ, SH3, HOOK and GUK domains)
KOG0694	Serine/threonine protein kinase
KOG3550	Receptor targeting protein Lin-7

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Drosophila melanogaster
KOG1217 - KOG3510	Fibrillin-2 - Big-2	FLJ90754 - FN1 FLJ14964 - FN1 LTBP3 - FN1 fibulin-1A - FN1	DIP:17306N - Ama SP1070 - CG31738 SP1070 - trol SP1070 - Robo DIP:17770N - DIP:20795N CG7447 - DIP:20795N DIP:18444N - Lac CG31999 - ImpL2 trol - CG31738 trol - CG30171 trol - Lac trol - Robo CG5639 - CG31738 CG5639 - trol CG5639 - Robo CG9572 - CG31738 CG9572 - trol CG9572 - Robo sli - CG30171 sli - trol
KOG0708 - KOG1217	Dlgh1 - Fibrillin-2	KIAA1526 - KIAA0816	pyd - DIP:18444N Dlt - Crb DIP:18367N - CG9572 DIP:18367N - CG31999 DIP:18367N - BG:DS00180.8 DIP:19213N - DIP:18444N dlg1 - CG9572 dlg1 - CG31999 dlg1 - BG:DS00180.8 GI:24657721 - BG:DS00180.10 GI:24657721 - CG31999 GI:24657721 - GI:24648166 scrib - CG31999 scrib - GI:24648166
KOG0694 - KOG0708	PKC-alpha - Dlgh1	PKN2 - CARD11 PRKCZ - CARD11	CG31140 - DIP:18367N CG31140 - dlg1
KOG0708 - KOG3550	Dlgh1 - Veli-3 Dlgh1 - PSD-95 Dlgh2 - PSD-95	MAGI-1B - LIN-7B PSD-95 - MAGI-1B PSD-95 - LIN-7B	cno - scrib dlg1 - DIP:18367N GI:24657721 - DIP:18367N

---

Conserved subnet 24:
4 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<6e-40).

Ortholog Groups
KOG1068	Exosomal 3'-5' exoribonuclease complex, subunit Rrp41 and related exoribonucleases
KOG1069	Exosomal 3'-5' exoribonuclease complex, subunit Rrp46
KOG3409	Exosomal 3'-5' exoribonuclease complex, subunit ski4 (Csl4)
KOG3013	Exosomal 3'-5' exoribonuclease complex, subunit Rrp4

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1068 - KOG1069	hRrp41p - hRrp46p hMtr3p - hRrp46p	Ski6 - Rrp46 Mtr3 - Rrp46	Mtr3 - Rrp46p SKI6 - Rrp46p
KOG1068 - KOG3409	hRrp41p - hCsl4p hMtr3p - hCsl4p	Ski6 - Csl4 Mtr3 - Csl4	Mtr3 - Csl4p SKI6 - Csl4p
KOG3013 - KOG3409	hRrp4p - hCsl4p	Rrp4 - Csl4	RRP4 - Csl4p
KOG1069 - KOG3409	hRrp46p - hCsl4p	Rrp46 - Csl4	Rrp46p - Csl4p

---

Conserved subnet 25:
4 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<2e-08).

Ortholog Groups
KOG0660	Mitogen-activated protein kinase
KOG3686	Rap1-GTPase-activating protein (Rap1GAP)
KOG3528	FOG: PDZ domain
KOG4177	Ankyrin
KOG3529	Radixin, moesin and related proteins of the ERM family

Conserved Interactions
Interaction	Rattus norvegicus	Drosophila melanogaster	Caenorhabditis elegans
KOG0660 - KOG3686	Mapk1 - Sipa1l1 Mapk13 - Sipa1l1	CG30171 - Rapgap1	MPK-1 - T27F2.2
KOG0660 - KOG3528	Mapk1 - PSD-95 Mapk13 - PSD-95	CG30171 - X11L CG30171 - Patj	MPK-1 - DIP:26387N MPK-1 - ZK849.2
KOG3528 - KOG4177	PSD-95 - Shank1 PSD-95 - ProSAP1	CG6619 - rols DIP:18367N - DIP:20678N DIP:18367N - DIP:18260N DIP:18367N - DIP:17228N DIP:18367N - CG17419 DIP:18367N - CG4719 Patj - Mbs Sip1 - DIP:18029N CG6688 - CG17419 CG6688 - DIP:18029N scrib - DIP:18029N INAD - DIP:23847N	ZK849.2 - unc-44 ZK849.2 - B0350.2 DIP:26387N - unc-44 DIP:26387N - B0350.2
KOG3528 - KOG3529	MUPP1 - Rdx	CG6619 - Mer Patj - Mer Patj - Moe scrib - Moe scrib - Mer Bazooka - Mer	C01F6.6 - C01G8.5

---

Conserved subnet 26:
4 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<5e-18).

Ortholog Groups
KOG3656	FOG: 7 transmembrane receptor
HG20215	Homologene family 20215
KOG3528	FOG: PDZ domain
KOG3529	Radixin, moesin and related proteins of the ERM family

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Drosophila melanogaster
KOG3656 - HG20215	D2R - D4R D3R - D4R	D4.2 - D4.4 beta-1-AR - D4.4 GI:4503387 - D4.4 D4.7 - D4.4	Rh1 - DIP:769N
KOG3528 - KOG3656	PSD-95 - beta-1-AR PSD-95 - Drd1a MUPP1 - D3R MUPP1 - D2R	NHERF-2 - beta-2-AR EBP50 - beta-2-AR	DIP:18367N - Rh1 scrib - DIP:17278N X11L - Rh1 INAD - Rh1
KOG3529 - KOG3656	Rdx - D3R	radixin - beta-2-AR Merlin - beta-2-AR moesin - beta-2-AR	Mer - CG18553
KOG3528 - KOG3529	MUPP1 - Rdx	Ezrin-Radixin-Moesin Binding Phosphoprotein 50 - moesin EBP50 - moesin EBP50 - Merlin EBP50 - radixin EBP50 - ezrin	CG6619 - Mer Patj - Mer Patj - Moe scrib - Moe scrib - Mer Bazooka - Mer

---

Conserved subnet 27:
4 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<5e-08).

Ortholog Groups
KOG0586	Serine/threonine protein kinase
KOG3417	Ras1 guanine nucleotide exchange factor
KOG0578	p21-activated serine/threonine protein kinase
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG0940	Ubiquitin protein ligase RSP5/NEDD4

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG0586 - KOG3417	DIP:320N - mSos1	DIP:133N - Sos1	Ykl116c - Lte1p
KOG0578 - KOG1703	PAK1 - Paxillin	PAK - ARA55	Ste20 - Ykr090w Cla4 - Ykr090w
KOG0578 - KOG3417	PAK1 - mSos1	PAK - Sos1	Cla4 - Lte1p Skm1 - Lte1p
KOG0578 - KOG0940	PAK1 - Itch	PAK - SMURF1 PAK - SMURF2 PAK - SMURF1 PAK - FLJ32109 PAK - KIAA1301 PAK - NEDD4	Ste20 - Rsp5 Cla4 - Rsp5

---

Conserved subnet 28:
4 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<2e-05).

Ortholog Groups
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins
KOG3529	Radixin, moesin and related proteins of the ERM family
KOG0940	Ubiquitin protein ligase RSP5/NEDD4
KOG0660	Mitogen-activated protein kinase
KOG3701	TGFbeta receptor signaling protein SMAD and related proteins

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG1703 - KOG3529	Paxillin - Nf2	stck - Mer unc-115 - Mer DIP:17600N - Moe DIP:17600N - Mer DIP:17944N - Moe CG32018 - Mer DIP:21964N - Mer	EAT-1 - NFM-1 C34B2.4 - C01G8.5
KOG0940 - KOG1703	Smurf1 - Cypher1	CG7552 - CG32018 CG7552 - stck Nedd4 - stck	Y65B4BR.4 - EAT-1 F13E6.4 - EAT-1 F13E6.4 - C28H8.6
KOG0660 - KOG0940	Mapk14 - Smurf1	CG30171 - Nedd4	MPK-1 - Y65B4BR.4 MPK-1 - F13E6.4
KOG0660 - KOG3701	Mapk14 - Smad3	CG32703 - Mad	B0218.3 - ZK370.2 B0218.3 - R13F6.9 MPK-1 - ZK370.2 MPK-1 - R13F6.9

---

Conserved subnet 29:
4 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<1e-03).

Ortholog Groups
KOG0594	Protein kinase PCTAIRE and related kinases
KOG0653	Cyclin B and related kinase-activating proteins
KOG1636	DNA polymerase delta processivity factor (proliferating cell nuclear antigen)
KOG1721	FOG: Zn-finger

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG0594 - KOG0653	Cdk1 - Cyclin B1	CDC2 - cyclin B2 CDC2 - Cyclin B1 CDK4 - Cyclin B1 CDK2 - DIP:24234N CDK2 - Cyclin B1	Cdc28 - Cln3 Cdc28 - Clb2 Cdc28 - Clb3 Cdc28 - Cln1 Cdc28 - Cln2 Cdc28 - Clb6 Cdc28 - Clb5 Cdc28 - Clb4 Cdc28 - Clb1 Cak1 - Cln3 Cak1 - Clb2 Cak1 - Clb3 Cak1 - Cln1 Cak1 - Cln2 Cak1 - Clb6 Cak1 - Clb5 Cak1 - Clb4 Cak1 - Clb1
KOG0594 - KOG1636	Cdk1 - Pcna CDK4 - Pcna	CDC2 - PCNA CDK2 - PCNA	Cdc28 - Pol30
KOG0594 - KOG1721	CDK4 - ZAC1	CDC2 - KLF6 CDC2 - Sp1 CDC2 - YY1 CDK4 - OSR1 CDK4 - KLF6 CDK4 - PLAG1 CDK4 - HIVEP1 CDK4 - SIP1 CDK4 - ZNF83 CDK4 - FLJ12586 CDK4 - PLAGL1 CDK4 - PRDM4 CDK4 - PLZF CDK4 - Sp1 CDK6 - OSR1 CDK6 - KLF6 CDK2 - KLF6 CDK2 - PLAG1 CDK2 - HIVEP1 CDK2 - SIP1 CDK2 - ZNF83 CDK2 - FLJ12586 CDK2 - PLAGL1 CDK2 - PRDM4 CDK2 - PLZF CDK2 - Sp1 PFTK1 - OSR1	Cdc28 - Swi5 Cdc28 - Ace2 Cdc28 - Crz1p Cdc28 - DIP:6487N Cdc28 - Ygr067c Cdc28 - RIM101 Cdc28 - Nrg2 Cak1 - Swi5 Cak1 - Ace2
KOG1721 - KOG1721	Egr1 - Egr1	ZNF-U69274 - ZFD25 DIP:36N - YY1 FLJ20765 - E4F1 FLJ20765 - ZF6 FLJ20765 - SIP1 FLJ20765 - ZNF83 FLJ23392 - zid FLJ23392 - ZFP106 IMAGE 3948563 - SIP1 IMAGE 3948563 - KIAA0972 IMAGE 3948563 - ZNF76 YY1 - DIP:36N YY1 - AEBP2 YY1 - Egr1 Miz-1 - DIP:5990N Miz-1 - Sp1 PLZF - Sp1 PLZF - BCL6 PLZF - PLAG1 PLZF - HIVEP1 PLZF - SIP1 PLZF - ZNF83 PLZF - FLJ12586 PLZF - PLAGL1 PLZF - PRDM4 PLZF - Egr1 PLZF - zid ZFP106 - zid ZFP106 - FLJ23392 ZNF76 - IMAGE 3948563 ZNF76 - SIP1 ZNF76 - KIAA0972 MGC4054 - SIP1 ZNF83 - E4F1 ZNF83 - ZF6 ZNF83 - SIP1 ZNF83 - FLJ20765 ZNF83 - PLAG1 ZNF83 - HIVEP1 ZNF83 - FLJ12586 ZNF83 - PLAGL1 ZNF83 - PRDM4 ZNF83 - PLZF zid - BCL6 zid - ZFP106 zid - FLJ23392 zid - PLZF CTCF - DIP:5990N PRDM4 - PLAG1 PRDM4 - HIVEP1 PRDM4 - SIP1 PRDM4 - ZNF83 PRDM4 - FLJ12586 PRDM4 - PLAGL1 PRDM4 - PLZF AEBP2 - YY1 FLJ12586 - PLAG1 FLJ12586 - HIVEP1 FLJ12586 - SIP1 FLJ12586 - ZNF83 FLJ12586 - PLAGL1 FLJ12586 - PRDM4 FLJ12586 - PLZF COASTER - RLF SIP1 - E4F1 SIP1 - ZF6 SIP1 - ZNF83 SIP1 - FLJ20765 SIP1 - PLAG1 SIP1 - HIVEP1 SIP1 - FLJ12586 SIP1 - PLAGL1 SIP1 - PRDM4 SIP1 - PLZF SIP1 - MGC4054 SIP1 - IMAGE 3948563 SIP1 - KIAA0972 SIP1 - ZNF76 Egr1 - Sp1 Egr1 - PLZF Egr1 - YY1 DIP:5990N - Miz-1 DIP:5990N - CTCF KIAA0972 - IMAGE 3948563 KIAA0972 - SIP1 KIAA0972 - ZNF76 ZF6 - E4F1 ZF6 - SIP1 ZF6 - ZNF83 ZF6 - FLJ20765 ZFD25 - ZNF-U69274 HIVEP1 - PLAG1 HIVEP1 - SIP1 HIVEP1 - ZNF83 HIVEP1 - FLJ12586 HIVEP1 - PLAGL1 HIVEP1 - PRDM4 HIVEP1 - PLZF E4F1 - ZF6 E4F1 - SIP1 E4F1 - ZNF83 E4F1 - FLJ20765 RLF - COASTER BCL6 - BCL6 BCL6 - zid BCL6 - PLZF PLAGL1 - PLAG1 PLAGL1 - HIVEP1 PLAGL1 - SIP1 PLAGL1 - ZNF83 PLAGL1 - FLJ12586 PLAGL1 - PRDM4 PLAGL1 - PLZF Sp1 - Egr1 Sp1 - PLZF Sp1 - Miz-1 PLAG1 - HIVEP1 PLAG1 - SIP1 PLAG1 - ZNF83 PLAG1 - FLJ12586 PLAG1 - PLAGL1 PLAG1 - PRDM4 PLAG1 - PLZF	Nrg2 - MIG1 Nrg2 - Nrg1p Swi5 - MIG1 Swi5 - Ace2 ADR1 - MIG1 ADR1 - Ace2 ADR1 - Ygr067c ADR1 - Yer028c Ydr437w - Msn4p Yer028c - Ygr067c Yer028c - MIG1 Yer028c - ADR1 MIG1 - ADR1 MIG1 - Ygr067c MIG1 - Yer028c MIG1 - Nrg1p MIG1 - Nrg2 MIG1 - Swi5 Ygr067c - MIG1 Ygr067c - Yer028c Ygr067c - ADR1 Ygr067c - DIP:6487N RIM101 - Zap1 Met32p - Met31 Nrg1p - MIG1 Nrg1p - Nrg2 Zap1 - RIM101 Ace2 - ADR1 Ace2 - Swi5 Met31 - Met32p DIP:6487N - Ygr067c Msn4p - Ydr437w

---

Conserved subnet 30:
4 conserved interactions between 5 ortholog groups.
This subnet exists in 3 organisms (p<5e-18).

Ortholog Groups
KOG0603	Ribosomal protein S6 kinase
KOG0660	Mitogen-activated protein kinase
KOG0578	p21-activated serine/threonine protein kinase
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
HG48145	Homologene family 48145

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Arabidopsis thaliana
KOG0603 - KOG0660	Rsk2 - Mapk1	Rsk3 - ERK2 RSK2 - Erk1	MPK5 - MPK4 MPK5 - MPK6
KOG0578 - KOG0660	PAK1 - Mapk1 PAK1 - Erk1	PAK - MAPK13 PAK - p38-alpha	MPK5 - MPK4 MPK5 - MPK6
KOG0581 - HG48145	erk2 - Raf1 MEK - Raf1	MEK2 - c-Raf MEK1 - c-Raf	MKK2 - MPK5
KOG0581 - KOG0660	erk2 - Mapk1 erk2 - Erk1 erk2 - Mapk14 MEK - Mapk1 MEK - Erk1	MKK5 - ERK5 MEK2 - ERK2 MEK2 - Erk1 MEK1 - ERK2 MEK1 - Erk1	MPK5 - MPK4 MPK5 - MPK6 MKK2 - MPK4 MKK2 - MPK6 MKK2 - MPK5

---

Conserved subnet 31:
4 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<7e-15).

Ortholog Groups
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0603	Ribosomal protein S6 kinase
KOG0660	Mitogen-activated protein kinase
KOG0658	Glycogen synthase kinase-3

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Arabidopsis thaliana
KOG0581 - KOG0603	MEK2 - Rsk3 MEK1 - Rsk3	MEK-2 - T01H8.1	MKK2 - MPK5
KOG0581 - KOG0660	MKK5 - ERK5 MEK2 - ERK2 MEK2 - Erk1 MEK1 - ERK2 MEK1 - Erk1	MEK-2 - MPK-1	MPK5 - MPK4 MPK5 - MPK6 MKK2 - MPK4 MKK2 - MPK6 MKK2 - MPK5
KOG0603 - KOG0660	Rsk3 - ERK2 RSK2 - Erk1	T01H8.1 - MPK-1	MPK5 - MPK4 MPK5 - MPK6
KOG0658 - KOG0660	DIP:878N - p38-2 DIP:878N - ERK2 GSK3-alpha - Erk1 GSK3-beta - Erk1	Y18D10A.5 - B0218.3 Y18D10A.5 - MPK-1	MPK5 - MPK4 MPK5 - MPK6

---

Conserved subnet 32:
3 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<1e-13).

Ortholog Groups
KOG1025	Epidermal growth factor receptor EGFR and related tyrosine kinases
KOG2996	Rho guanine nucleotide exchange factor VAV3
HG4049	Homologene family 4049

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG1025 - KOG2996	ErbB-3 - PI3K p85	GI:6754360 - PI3K p85-alpha	DIP:133N - Vav DIP:320N - Vav DIP:491N - Vav EGFR - Vav2 EGFR - Vav EGFR - DIP:1061N
KOG2996 - HG4049	PI3K p85 - IRS-1	PI3K p85-alpha - IRS-1	Vav - IRS-1
KOG1025 - HG4049	ErbB-3 - IRS-1	GI:6754360 - IRS-1	DIP:133N - IRS-1 EGFR - IRS-1

---

Conserved subnet 33:
3 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<2e-16).

Ortholog Groups
KOG0708	Membrane-associated guanylate kinase MAGUK (contains PDZ, SH3, HOOK and GUK domains)
KOG3550	Receptor targeting protein Lin-7
HG41157	Homologene family 41157
KOG0609	Calcium/calmodulin-dependent serine protein kinase/membrane-associated guanylate kinase

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG0708 - KOG3550	Dlgh1 - Lin-7 PSD-95 - CIPP DLG2 - CIPP DLG2 - Lin-7	MAGI-1B - LIN-7B PSD-95 - MAGI-1B PSD-95 - LIN-7B	cno - scrib dlg1 - DIP:18367N GI:24657721 - DIP:18367N
KOG0708 - HG41157	Dlgh1 - SAP102 PSD-95 - SAP102 DLG2 - SAP102	CHAPSYN-110 - SAP-102 PSD-95 - SAP-102 DLG1 - SAP-102	cno - scrib pyd - pyd pyd - pyd DIP:19213N - pyd dlg1 - DIP:18367N GI:24657721 - DIP:18367N scrib - cno
KOG0609 - KOG0708	Pals1 - Dlgh1	Lin-2 - DLG1	CG9326 - veli

---

Conserved subnet 34:
3 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<4e-22).

Ortholog Groups
KOG1299	Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
KOG3202	SNARE protein TLG1/Syntaxin 6
KOG0811	SNARE protein PEP12/VAM3/Syntaxin 7/Syntaxin 17

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG1299 - KOG3202	Vps45 - Stx8 Vps45 - Stx6	VPS45A - STX8 VPS45A - Syntaxin 6	VPS45 - TLG1 VPS45 - VAM7
KOG0811 - KOG1299	Stx7 - Vps45	STX7 - VPS45A	Pep12 - VPS45 Vam3 - VPS45
KOG0811 - KOG3202	Stx7 - Stx8 Stx7 - Stx6 Syntaxin 7 - Stx8	STX7 - STX8 STX7 - Syntaxin 6	Pep12 - TLG1 Pep12 - VAM7 Vam3 - VAM7 Vam3 - TLG1

---

Conserved subnet 35:
3 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<9e-19).

Ortholog Groups
KOG0989	Replication factor C, subunit RFC4
KOG0990	Replication factor C, subunit RFC5
KOG0991	Replication factor C, subunit RFC2

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0989 - KOG0990	RFC37 - RFC5	CG8142 - RfC3	Rfc2 - Rfc3
KOG0989 - KOG0991	RFC37 - RFC2	CG8142 - RfC40	Rfc2 - Rfc4
KOG0990 - KOG0991	RFC5 - RFC2	RfC3 - RfC40	Rfc3 - Rfc4

---

Conserved subnet 36:
3 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<8e-09).

Ortholog Groups
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0660	Mitogen-activated protein kinase
KOG0594	Protein kinase PCTAIRE and related kinases
KOG0658	Glycogen synthase kinase-3

Conserved Interactions
Interaction	Caenorhabditis elegans	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0581 - KOG0660	MEK-2 - MPK-1	Ste7 - Kss1 Ste7 - Fus3 Ste7 - Slt2 Pbs2 - Hog1 Pbs2 - Kss1 Pbs2 - Fus3 Mkk1 - Slt2 Mkk1 - Smk1 Mkk2 - Slt2 Mkk2 - Kss1 Mkk2 - Smk1	MPK5 - MPK4 MPK5 - MPK6 MKK2 - MPK4 MKK2 - MPK6 MKK2 - MPK5
KOG0594 - KOG0660	T05G5.3 - B0218.3	Cdc28 - Kss1 Cdc28 - Fus3 Cdc28 - Smk1 Cdc28 - Hog1 Cdc28 - Slt2 Cak1 - Smk1 Cak1 - Slt2	MPK5 - MPK4 MPK5 - MPK6
KOG0658 - KOG0660	Y18D10A.5 - B0218.3 Y18D10A.5 - MPK-1	RIM11 - Kss1 Yol128c - Slt2	MPK5 - MPK4 MPK5 - MPK6

---

Conserved subnet 37:
3 conserved interactions between 4 ortholog groups.
This subnet exists in 3 organisms (p<5e-10).

Ortholog Groups
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0660	Mitogen-activated protein kinase
KOG0590	Checkpoint kinase and related serine/threonine protein kinases
KOG0658	Glycogen synthase kinase-3

Conserved Interactions
Interaction	Homo sapiens	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0581 - KOG0660	MKK5 - ERK5 MEK2 - ERK2 MEK2 - Erk1 MEK1 - ERK2 MEK1 - Erk1	Ste7 - Kss1 Ste7 - Fus3 Ste7 - Slt2 Pbs2 - Hog1 Pbs2 - Kss1 Pbs2 - Fus3 Mkk1 - Slt2 Mkk1 - Smk1 Mkk2 - Slt2 Mkk2 - Kss1 Mkk2 - Smk1	MPK5 - MPK4 MPK5 - MPK6 MKK2 - MPK4 MKK2 - MPK6 MKK2 - MPK5
KOG0590 - KOG0660	CHEK1 - MAPK13	Chk1 - Mlp1 Chk1 - Kss1	MPK5 - MPK4 MPK5 - MPK6
KOG0658 - KOG0660	DIP:878N - p38-2 DIP:878N - ERK2 GSK3-alpha - Erk1 GSK3-beta - Erk1	RIM11 - Kss1 Yol128c - Slt2	MPK5 - MPK4 MPK5 - MPK6

---

Conserved subnet 38:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<1e-09).

Ortholog Groups
KOG3594	FOG: Cadherin repeats
KOG4203	Armadillo/beta-Catenin/plakoglobin
KOG0658	Glycogen synthase kinase-3

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG3594 - KOG4203	N-cadherin - beta-catenin	CDH1 - Beta-catenin	E-cadherin - Beta-catenin
KOG0658 - KOG4203	GSK-3-beta - beta-catenin	GSK3-beta - Beta-catenin	GSK3-alpha - Beta-catenin GSK3-beta - Beta-catenin

---

Conserved subnet 39:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<4e-13).

Ortholog Groups
KOG1466	Translation initiation factor 2B, alpha subunit (eIF-2Balpha/GCN3)
KOG1467	Translation initiation factor 2B, delta subunit (eIF-2Bdelta/GCD2)
KOG1465	Translation initiation factor 2B, beta subunit (eIF-2Bbeta/GCD7)

Conserved Interactions
Interaction	Rattus norvegicus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1466 - KOG1467	EIF2B1 - EIF2B4	eIF2B-delta - DIP:17444N	Gcn3 - Gcd2
KOG1465 - KOG1467	EIF2B2 - EIF2B4	eIF2B-beta - eIF2B-delta eIF2B-beta - DIP:17444N	Gcd7 - Gcd2

---

Conserved subnet 40:
2 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-11).

Ortholog Groups
KOG0985	Vesicle coat protein clathrin, heavy chain
KOG3771	Amphiphysin

Conserved Interactions
Interaction	Rattus norvegicus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0985 - KOG3771	clathrin - amphiphysin 1 clathrin - amphiphysin 2	Chc - Amph	Chc1 - Rvs167 Chc1 - Rvs161
KOG3771 - KOG3771	amphiphysin 2 - amphiphysin 1 amphiphysin 1 - amphiphysin 1 amphiphysin 1 - amphiphysin 2	Amph - Amph	Rvs161 - Rvs167 Rvs167 - Rvs167 Rvs167 - Rvs161

---

Conserved subnet 41:
2 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<5e-19).

Ortholog Groups
KOG2660	Locus-specific chromosome binding proteins
HG68400	Homologene family 68400

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG2660 - HG68400	Bmi1 - Mph1	BMI1 - HPH1 BMI1 - HPH2	l(3)73Ah - ph-d
KOG2660 - KOG2660	Bmi1 - Bmi1	BMI1 - BMI1	Psc - Psc Psc - l(3)73Ah l(3)73Ah - Psc

---

Conserved subnet 42:
2 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-10).

Ortholog Groups
KOG0639	Transducin-like enhancer of split protein (contains WD40 repeats)
KOG4119	G protein gamma subunit

Conserved Interactions
Interaction	Mus musculus	Bos taurus	Homo sapiens
KOG0639 - KOG4119	DIP:604N - DIP:587N DIP:604N - DIP:586N DIP:604N - DIP:494N DIP:604N - DIP:471N DIP:604N - DIP:324N DIP:604N - DIP:203N	Transducin - G Protein Gi Gamma 2 Transducin - Transducin	DIP:604N - DIP:471N
KOG0639 - KOG0639	Tle1 - Tle1	Transducin - Transducin	TLE1 - TLE1 TLE1 - AES TLE1 - TLE3 TLE3 - AES TLE3 - TLE1 AES - AES AES - TLE3 AES - TLE1

---

Conserved subnet 43:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<1e-07).

Ortholog Groups
KOG3601	Adaptor protein GRB2, contains SH2 and SH3 domains
KOG4226	Adaptor protein NCK/Dock, contains SH2 and SH3 domains
KOG1264	Phospholipase C

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG3601 - KOG4226	Grb2 - Sorbs1 Grb2 - Nck Gads - Nck	Grap - Nck Grb2 - Nck Gads - Nck	dock - dock Dap160 - dock drk - Dap160
KOG1264 - KOG3601	Plcg1 - Gads Plcg1 - Grb2	PLCG1 - Grb2 PLC-gamma - Grb2 PLC-gamma - Grap PLC-gamma - Gads PLCG2 - Gads	Gap1 - drk

---

Conserved subnet 44:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<9e-11).

Ortholog Groups
KOG0678	Actin-related protein Arp2/3 complex, subunit Arp3
KOG1755	Profilin
KOG1523	Actin-related protein Arp2/3 complex, subunit ARPC1/p41-ARC

Conserved Interactions
Interaction	Bos taurus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0678 - KOG1755	Actin-Like Protein 3 - 2BTF_P Actin-Like Protein 3 - Profilin	Arp66B - Profilin	Actin - Pfy1
KOG0678 - KOG1523	Actin-Like Protein 3 - Arp23 COMPLEX 41 KDA SUBUNIT	Arp66B - Sop2	ARP3 - Arc40

---

Conserved subnet 45:
2 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-07).

Ortholog Groups
KOG0837	Transcriptional activator of the JUN family
KOG1414	Transcriptional activator FOSB/c-Fos and related bZIP transcription factors

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG0837 - KOG1414	JunB - c-Fos JunB - DIP:1067N c-Jun - DIP:1067N c-Jun - c-Fos	JunD - p21SNFT JunD - Fra2 JunD - Fra1 JunD - c-Fos JunD - FosB JunD - ATFa2 JunD - B-ATF JunD - ATF-3 JUNB - ATF-3 JUNB - B-ATF JUNB - ATFa2 JUNB - FosB JUNB - c-Fos JUNB - Fra1 JUNB - Fra2 JUNB - p21SNFT c-Jun - p21SNFT c-Jun - Fra2 c-Jun - Fra1 c-Jun - c-Fos c-Jun - FosB c-Jun - ATFa2 c-Jun - B-ATF c-Jun - ATF-3	Jra - A3-3
KOG0837 - KOG0837	JunB - c-Jun c-Jun - c-Jun c-Jun - JunB	JunD - c-Jun JunD - JUNB C-Jun Homodimer - C-Jun Homodimer JUNB - c-Jun JUNB - JunD c-Jun - c-Jun c-Jun - JUNB c-Jun - JunD	Jra - Jra

---

Conserved subnet 46:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<3e-13).

Ortholog Groups
KOG0811	SNARE protein PEP12/VAM3/Syntaxin 7/Syntaxin 17
KOG3202	SNARE protein TLG1/Syntaxin 6
KOG0809	SNARE protein TLG2/Syntaxin 16

Conserved Interactions
Interaction	Mus musculus	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0811 - KOG3202	Stx7 - Stx8 Stx7 - Stx6 Syntaxin 7 - Stx8	Pep12 - TLG1 Pep12 - VAM7 Vam3 - VAM7 Vam3 - TLG1	SYP21 - SYP51 SYP21 - SYP61 SYP22 - SYP51 SYP22 - SYP61
KOG0809 - KOG3202	Stx16 - Stx6	TLG2 - TLG1 TLG2 - VAM7	SYP42 - SYP61 SYP42 - SYP51 SYP41 - SYP61 SYP41 - SYP51

---

Conserved subnet 47:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<8e-14).

Ortholog Groups
KOG1299	Vacuolar sorting protein VPS45/Stt10 (Sec1 family)
KOG3202	SNARE protein TLG1/Syntaxin 6
KOG0809	SNARE protein TLG2/Syntaxin 16

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1299 - KOG3202	Vps45 - Stx8 Vps45 - Stx6	CG8228 - DIP:21890N	VPS45 - TLG1 VPS45 - VAM7
KOG0809 - KOG3202	Stx16 - Stx6	Syx16 - DIP:21890N	TLG2 - TLG1 TLG2 - VAM7

---

Conserved subnet 48:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<3e-06).

Ortholog Groups
KOG0836	F-actin capping protein, alpha subunit
KOG0901	60S ribosomal protein L14/L17/L23
KOG0746	60S ribosomal protein L3 and related proteins

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0836 - KOG0901	CAPZA2 - RPL23	CG10540 - RpL17A	Cap1 - RPL23B
KOG0746 - KOG0901	RPL3 - RPL23	DIP:17151N - RpL17A RpL3 - RpL17A	60s Ribosomal Protein L3 - RPL23B

---

Conserved subnet 49:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<3e-15).

Ortholog Groups
KOG4787	Uncharacterized conserved protein
HG68224	Homologene family 68224
KOG4674	Uncharacterized conserved coiled-coil protein

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Oryza sativa
KOG4787 - HG68224	CG18304 - CG3493	DIP:25932N - C14H10.2 DIP:25932N - F01G10.5 DIP:25932N - LIN-5 LFI-1 - LIN-5	myosin heavy chain-like protein - putative CCAAT displacement protein myosin heavy chain-like protein - Kinesin-like calmodulin-binding protein-like protein Putative myosin - OSJNBB0073N24.16 OSJNBB0073N24.16 - Putative myosin OSJNBB0073N24.16 - centromere protein-like protein
KOG4674 - HG68224	Bx34 - CG3493 Mhc - Mhc	C14H10.2 - DIP:25932N DIP:25932N - C14H10.2 DIP:25932N - F01G10.5 DIP:25932N - LIN-5 MYO-2 - UNC-54 LFI-1 - LIN-5 UNC-54 - MYO-2 F01G10.5 - LIN-5 F01G10.5 - DIP:25932N	putative CCAAT displacement protein - myosin heavy chain-like protein putative CCAAT displacement protein - Kinesin-like calmodulin-binding protein-like protein myosin heavy chain-like protein - putative CCAAT displacement protein myosin heavy chain-like protein - Kinesin-like calmodulin-binding protein-like protein centromere protein-like protein - OSJNBB0073N24.16 Putative myosin - OSJNBB0073N24.16 OSJNBB0073N24.16 - Putative myosin OSJNBB0073N24.16 - centromere protein-like protein

---

Conserved subnet 50:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<6e-11).

Ortholog Groups
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
HG8056	Homologene family 8056
KOG0660	Mitogen-activated protein kinase

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Arabidopsis thaliana
KOG0581 - HG8056	Map2k2 - MEKK1 Map2k1 - MEKK1	MEK - MEKK1	MKK2 - MPK5
KOG0581 - KOG0660	Map2k2 - Mapk1 Map2k1 - Mapk1	erk2 - Mapk1 erk2 - Erk1 erk2 - Mapk14 MEK - Mapk1 MEK - Erk1	MPK5 - MPK4 MPK5 - MPK6 MKK2 - MPK4 MKK2 - MPK6 MKK2 - MPK5

---

Conserved subnet 51:
2 conserved interactions between 3 ortholog groups.
This subnet exists in 3 organisms (p<4e-04).

Ortholog Groups
KOG0660	Mitogen-activated protein kinase
KOG1241	Karyopherin (importin) beta 1
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Saccharomyces cerevisiae
KOG0660 - KOG1241	Mapk1 - Kpnb1	Erk1 - Imp-beta Mapk1 - Imp-beta	Kss1 - Kap95 Slt2 - Kap95
KOG0581 - KOG0660	Map2k2 - Mapk1 Map2k1 - Mapk1	erk2 - Mapk1 erk2 - Erk1 erk2 - Mapk14 MEK - Mapk1 MEK - Erk1	Ste7 - Kss1 Ste7 - Fus3 Ste7 - Slt2 Pbs2 - Hog1 Pbs2 - Kss1 Pbs2 - Fus3 Mkk1 - Slt2 Mkk1 - Smk1 Mkk2 - Slt2 Mkk2 - Kss1 Mkk2 - Smk1

---

Conserved subnet 52:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-09).

Ortholog Groups
KOG1461	Translation initiation factor 2B, epsilon subunit (eIF-2Bepsilon/GCD6)
KOG1462	Translation initiation factor 2B, gamma subunit (eIF-2Bgamma/GCD1)

Conserved Interactions
Interaction	Rattus norvegicus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1461 - KOG1462	EIF2B5 - EIF2B3	eIF2B-epsilon - eIF2B-gamma	Gcd6 - Gcd1

---

Conserved subnet 53:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-12).

Ortholog Groups
KOG3202	SNARE protein TLG1/Syntaxin 6
HG37846	Homologene family 37846

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Saccharomyces cerevisiae
KOG3202 - HG37846	Stx8 - Vamp8	Stx8 - VAMP8	TLG1 - Nyv1p VAM7 - Nyv1p

---

Conserved subnet 54:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-08).

Ortholog Groups
KOG0869	CCAAT-binding factor, subunit A (HAP3)
KOG1657	CCAAT-binding factor, subunit C (HAP5)

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Saccharomyces cerevisiae
KOG0869 - KOG1657	CFB-A - CBF-C	NF-YB - NF-YC	HAP3 - HAP5

---

Conserved subnet 55:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-09).

Ortholog Groups
KOG3573	Caspase, apoptotic cysteine protease
HG7653	Homologene family 7653

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG3573 - HG7653	procaspase 8 - procaspase 1	procaspase-8 - procaspase 1	CASP1 - caspase 1 caspase 4 - caspase 1 Caspase 6 - caspase 1 CASP1 - caspase 1 Casp-3 - caspase 1 CASP8 - caspase 1

---

Conserved subnet 56:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<3e-04).

Ortholog Groups
KOG1164	Casein kinase (serine/threonine/tyrosine protein kinase)

Conserved Interactions
Interaction	Rattus norvegicus	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1164 - KOG1164	Csnk1d - Csnk1d	F46F2.2 - F46F2.2	Hrr25 - Hrr25

---

Conserved subnet 57:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-10).

Ortholog Groups
KOG0662	Cyclin-dependent kinase CDK5
KOG3932	CDK5 kinase activator p35/Nck5a

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG0662 - KOG3932	Cdk5 - p25	Cdk5 - p25	Cdk5 - p35

---

Conserved subnet 58:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<3e-10).

Ortholog Groups
KOG3006	Transthyretin and related proteins

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Caenorhabditis elegans
KOG3006 - KOG3006	Ttr - Ttr	TTR - TTR TTR - TTR TTR - TTR TTR - TTR	R09H10.3 - R09H10.3 DIP:25455N - DIP:25455N

---

Conserved subnet 59:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-09).

Ortholog Groups
KOG3589	G protein signaling regulators
KOG3938	RGS-GAIP interacting protein GIPC, contains PDZ domain

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG3589 - KOG3938	GAIP - GIPC	Rgs19 - Rgs19ip1	GAIP - GIPC

---

Conserved subnet 60:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-03).

Ortholog Groups
KOG3528	FOG: PDZ domain
HG8189	Homologene family 8189

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Drosophila melanogaster
KOG3528 - HG8189	PSD-95 - Acvrip1 S-SCAM-beta - Acvrip1	MUPP1 - MAGI-2	CG14168 - GI:24657721 CG15617 - DIP:18367N DIP:18367N - GI:24657721 Sip1 - Ima Sip1 - scrib scrib - Ima

---

Conserved subnet 61:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<1e-08).

Ortholog Groups
KOG2371	Molybdopterin biosynthesis protein

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Arabidopsis thaliana
KOG2371 - KOG2371	Gephyrin - Gephyrin	GPHN - GPHN	Molybdopterin Biosynthesis Cnx1 Protein - Molybdopterin Biosynthesis Cnx1 Protein

---

Conserved subnet 62:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-02).

Ortholog Groups
KOG0594	Protein kinase PCTAIRE and related kinases
KOG1163	Casein kinase (serine/threonine/tyrosine protein kinase)

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Drosophila melanogaster
KOG0594 - KOG1163	CDK1 - Csnk1a1	CDK4 - CSNK1A1 CDK6 - CSNK1A1 PFTK1 - CSNK1A1	CG30171 - CK1-alpha

---

Conserved subnet 63:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-08).

Ortholog Groups
HG1423	Homologene family 1423

Conserved Interactions
Interaction	Rattus norvegicus	Bos taurus	Homo sapiens
HG1423 - HG1423	Crybb3 - Crybb3	Gammas Crystallin - Gammas Crystallin Gamma-D Crystallin - Gamma-D Crystallin	CRYBB1 - CRYBB1

---

Conserved subnet 64:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-04).

Ortholog Groups
KOG1025	Epidermal growth factor receptor EGFR and related tyrosine kinases
KOG3601	Adaptor protein GRB2, contains SH2 and SH3 domains

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Caenorhabditis elegans
KOG1025 - KOG3601	Erbb2 - Grb-2	DIP:133N - Grb2 EGFR - Grb2	DIP:1014N - sem-5

---

Conserved subnet 65:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-05).

Ortholog Groups
KOG0741	AAA+-type ATPase
KOG1586	Protein required for fusion of vesicles in vesicular transport, alpha-SNAP

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Saccharomyces cerevisiae
KOG0741 - KOG1586	NSF - alpha-SNAP	NSF - alpha-SNAP	Sec18p - Sec17

---

Conserved subnet 66:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-05).

Ortholog Groups
KOG1892	Actin filament-binding protein Afadin
KOG3516	Neurexin IV

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Drosophila melanogaster
KOG1892 - KOG3516	l-afadin - Neurexin II l-afadin - Neurexin III	KIAA0300 - KIAA0578	cno - Nrx cno - trol

---

Conserved subnet 67:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-07).

Ortholog Groups
KOG4292	Cubilin, multiligand receptor mediating cobalamin absorption
HG32049	Homologene family 32049

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Drosophila melanogaster
KOG4292 - HG32049	Cubilin - Megalin	DIP:6008N - DLK1	DIP:214N - Notch CG12908 - Notch CG12908 - GI:24584298

---

Conserved subnet 68:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-07).

Ortholog Groups
KOG3430	Dynein light chain type 1

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG3430 - KOG3430	PIN - PIN PIN - Dlc-2 Dlc-2 - PIN	DLC2 - DLC2	LC8 - LC8

---

Conserved subnet 69:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<6e-07).

Ortholog Groups
KOG1353	F0F1-type ATP synthase, alpha subunit
KOG1531	F0F1-type ATP synthase, gamma subunit

Conserved Interactions
Interaction	Rattus norvegicus	Bos taurus	Saccharomyces cerevisiae
KOG1353 - KOG1531	F1-Atpase Alpha Chain - F1-Atpase Gamma Chain	F1-Atpase - F1-Atpase	Atp1p - Atp3p

---

Conserved subnet 70:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-04).

Ortholog Groups
KOG0694	Serine/threonine protein kinase
KOG1703	Adaptor protein Enigma and related PDZ-LIM proteins

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Saccharomyces cerevisiae
KOG0694 - KOG1703	PKC-epsilon - ENH	PKC-delta - Cypher1 PKC-epsilon - Cypher1 PKC-epsilon - Paxillin	Pkc1 - LRG Pkc1 - Ykr090w

---

Conserved subnet 71:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<1e-10).

Ortholog Groups
HG55473	Homologene family 55473

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
HG55473 - HG55473	nNOS - nNOS	Nos2 - Nos2	NOS2A - NOS2A

---

Conserved subnet 72:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-07).

Ortholog Groups
KOG3656	FOG: 7 transmembrane receptor
KOG3938	RGS-GAIP interacting protein GIPC, contains PDZ domain

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Caenorhabditis elegans
KOG3656 - KOG3938	D2R - GIPC D3R - GIPC	beta-1-AR - GIPC alpha-2A-AR - GIPC	T23C6.5 - C35D10.2

---

Conserved subnet 73:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<5e-03).

Ortholog Groups
KOG0708	Membrane-associated guanylate kinase MAGUK (contains PDZ, SH3, HOOK and GUK domains)
KOG3209	WW domain-containing protein

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Caenorhabditis elegans
KOG0708 - KOG3209	Dlgh1 - PSD-95 Dlgh1 - S-SCAM-beta Dlgh2 - PSD-95	PSD-95 - MAGI-1B	dsh-1 - DIP:26963N dlg-1 - DIP:26963N C25F6.2 - DIP:26963N C34F11.9 - DIP:26963N F44D12.1 - DIP:26963N

---

Conserved subnet 74:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<4e-09).

Ortholog Groups
KOG2104	Nuclear transport factor 2

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Saccharomyces cerevisiae
KOG2104 - KOG2104	Nuclear Transport Factor 2 - Nuclear Transport Factor 2	NUTF2 - NUTF2	NTF2 - NTF2

---

Conserved subnet 75:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-05).

Ortholog Groups
KOG0665	Jun-N-terminal kinase (JNK)
KOG0837	Transcriptional activator of the JUN family

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens
KOG0665 - KOG0837	JNK - Jun	MAPK8 - c-Jun MAPK8 - JunB	JNK3alpha1 - c-Jun JNK3alpha1 - JUNB JNK3alpha1 - JunD JNK3alpha2 - c-Jun JNK3alpha2 - JUNB JNK3alpha2 - JunD JNK1beta1 - c-Jun JNK1beta1 - JUNB JNK1beta1 - JunD JNK1beta2 - c-Jun JNK1beta2 - JUNB JNK1beta2 - JunD JNK1alpha1 - c-Jun JNK1alpha1 - JUNB JNK1alpha1 - JunD JNK2alpha1 - c-Jun JNK2alpha1 - JUNB JNK2alpha1 - JunD JNK2alpha2 - c-Jun JNK2alpha2 - JUNB JNK2alpha2 - JunD JNK2beta1 - c-Jun JNK2beta1 - JUNB JNK2beta1 - JunD JNK2beta2 - c-Jun JNK2beta2 - JUNB JNK2beta2 - JunD

---

Conserved subnet 76:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<8e-08).

Ortholog Groups
KOG1775	U6 snRNA-associated Sm-like protein
KOG1781	Small Nuclear ribonucleoprotein splicing factor

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1775 - KOG1781	2310034K10Rik - 0910001B06Rik	CG6610 - CG13277	LSM5 - LSM7

---

Conserved subnet 77:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-05).

Ortholog Groups
KOG1025	Epidermal growth factor receptor EGFR and related tyrosine kinases
KOG4637	Adaptor for phosphoinositide 3-kinase

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG1025 - KOG4637	GI:6754360 - PI3K p85-alpha	DIP:133N - Vav Proto-Oncogene EGFR - PI3K p85-beta EGFR - Vav Proto-Oncogene EGFR - DIP:1061N	DER - Pi3K21B

---

Conserved subnet 78:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-03).

Ortholog Groups
KOG0616	cAMP-dependent protein kinase catalytic subunit (PKA)
KOG0841	Multifunctional chaperone (14-3-3 family)

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0616 - KOG0841	PKA - 14-3-3-tau	DIP:20399N - 14-3-3-epsilon CG30171 - 14-3-3-epsilon	TPK2 - Bmh2

---

Conserved subnet 79:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<8e-09).

Ortholog Groups
KOG1167	Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination
KOG4139	Protein kinase essential for the initiation of DNA replication

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG1167 - KOG4139	CDC7L1 - ASK	HsCdc7 - ASK	Cdc7 - Dbf4

---

Conserved subnet 80:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-09).

Ortholog Groups
KOG1785	Tyrosine kinase negative regulator CBL
HG74545	Homologene family 74545

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG1785 - HG74545	Cbl - EGFR	Cbl - DER BEST:GH09876 - DIP:18156N	SLI-1 - DIP:1014N

---

Conserved subnet 81:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<9e-09).

Ortholog Groups
KOG3124	Pyrroline-5-carboxylate reductase

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG3124 - KOG3124	1110058B13Rik - 1110058B13Rik	CG5840 - CG5840 CG5840 - DIP:19717N DIP:19717N - DIP:19717N DIP:19717N - CG5840 P5cr - P5cr	Pro3 - Pro3

---

Conserved subnet 82:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<7e-05).

Ortholog Groups
KOG2294	Transcription factor of the Forkhead/HNF3 family
KOG2684	Sirtuin 5 and related class III sirtuins (SIR2 family)

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG2294 - KOG2684	Foxo1 - Sirt1	FoxO3 - Sirt1 FoxO1 - Sirt1	Fkh1 - Sir2 Fhl1 - Sir2

---

Conserved subnet 83:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<3e-11).

Ortholog Groups
KOG4105	6-pyruvoyl tetrahydrobiopterin synthase

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG4105 - KOG4105	Pts - Pts	GI:24585378 - GI:24585378	DIP:25287N - DIP:25287N B0041.6 - B0041.6

---

Conserved subnet 84:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<7e-08).

Ortholog Groups
KOG4203	Armadillo/beta-Catenin/plakoglobin

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG4203 - KOG4203	Beta-catenin - Beta-catenin	UCK2 - UCK2 JUP - Beta-catenin Beta-catenin - JUP	Ydr020c - Urk1 Ydr020c - Ydr020c Ydr020c - Fur1p Fur1p - Urk1 Fur1p - Ydr020c Urk1 - Urk1 Urk1 - Fur1p Urk1 - Ydr020c

---

Conserved subnet 85:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 4 organisms (p<7e-08).

Ortholog Groups
KOG0852	Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG0852 - KOG0852	Thioredoxin Peroxidase 2 - Thioredoxin Peroxidase 2	Prdx3 - Prdx3	PRDX2 - PRDX2	cTPx II - cTPx II cTPx II - Tsa1 Tsa1 - cTPx II

---

Conserved subnet 86:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-05).

Ortholog Groups
KOG0695	Serine/threonine protein kinase
KOG3606	Cell polarity protein PAR6

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG0695 - KOG3606	aPKC-lambda - mPAR-6 aPKC-lambda - mPar-6A	aPKC - par-6 aPKC - SdtB	F09E5.1 - T26E3.3 E01H11.1 - T26E3.3

---

Conserved subnet 87:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<1e-10).

Ortholog Groups
KOG3367	Hypoxanthine-guanine phosphoribosyltransferase

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Caenorhabditis elegans
KOG3367 - KOG3367	Hprt - Hprt	HPRT1 - HPRT1	Y105E8B.5 - Y105E8B.5

---

Conserved subnet 88:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-06).

Ortholog Groups
KOG2332	Ferritin

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG2332 - KOG2332	Ftl1 - Ftl1	CG4349 - CG4349 Fer1HCH - Fer2LCH Fer1HCH - Fer1HCH Fer1HCH - Fer2LCH Fer1HCH - Fer1HCH Fer2LCH - Fer1HCH Fer2LCH - Fer1HCH	C54F6.14 - FTN-2 C54F6.14 - C54F6.14 FTN-2 - FTN-2 FTN-2 - C54F6.14

---

Conserved subnet 89:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-03).

Ortholog Groups
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0841	Multifunctional chaperone (14-3-3 family)

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG0581 - KOG0841	MEK - 14-3-3	DIP:27558N - 14-3-3-epsilon DIP:27558N - 14-3-3-beta DIP:27558N - 14.3.3-gamma DIP:27558N - 14-3-3tau MEK2 - 14-3-3-beta MEK2 - 14-3-3-zeta MEK2 - 14-3-3tau MEK1 - 14-3-3-beta MEK1 - 14-3-3-zeta MEK1 - 14-3-3tau	CG30171 - 14-3-3-epsilon

---

Conserved subnet 90:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-08).

Ortholog Groups
KOG2483	Upstream transcription factor 2/L-myc-2 protein
HG31092	Homologene family 31092

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG2483 - HG31092	dMax - c-Myc Max - c-Myc Mad4 - c-Myc Mad - c-Myc	C-Myc-Max Heterodimeric Leucine Zipper - C-Myc-Max Heterodimeric Leucine Zipper Max - c-Myc MAX - c-Myc Mad1 - c-Myc	Max - GI:24639496

---

Conserved subnet 91:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<9e-05).

Ortholog Groups
KOG3417	Ras1 guanine nucleotide exchange factor
KOG3601	Adaptor protein GRB2, contains SH2 and SH3 domains

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Caenorhabditis elegans
KOG3417 - KOG3601	mSos1 - Grb2	Sos1 - Grb2	SOS-1 - sem-5

---

Conserved subnet 92:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-08).

Ortholog Groups
KOG2093	Translesion DNA polymerase - REV1 deoxycytidyl transferase
KOG3186	Mitotic spindle checkpoint protein

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG2093 - KOG3186	Rev1 - Rev7	REV1 - MAD2B	Rev1 - CG2948

---

Conserved subnet 93:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<1e-08).

Ortholog Groups
KOG3804	Transcription factor NERF and related proteins, contain ETS domain

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG3804 - KOG3804	Ets1 - Ets1	ETV6 - ETV6	Yan - Yan

---

Conserved subnet 94:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-06).

Ortholog Groups
KOG0730	AAA+-type ATPase
KOG2042	Ubiquitin fusion degradation protein-2

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0730 - KOG2042	Vcp - Ube4b	DIP:20323N - CG2218 CG12010 - CG2218	Cdc48 - Ufd2

---

Conserved subnet 95:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<3e-08).

Ortholog Groups
KOG3067	Translin family protein

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG3067 - KOG3067	TB-RBP - TB-RBP	Translin - Translin	CG11761 - CG11761

---

Conserved subnet 96:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<9e-05).

Ortholog Groups
KOG3667	STAT protein

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Caenorhabditis elegans
KOG3667 - KOG3667	Stat5A - Stat5B Stat5B - Stat5A Stat6 - Stat6	Stat4 - Stat5b Stat4 - STAT5a Stat4 - Stat3 Stat4 - STAT6 Stat4 - STAT1-beta STAT1-beta - Stat5b STAT1-beta - STAT5a STAT1-beta - Stat3 STAT1-beta - STAT6 STAT1-beta - Stat4 STAT1-beta - Stat2 STAT6 - STAT6 STAT6 - Stat5b STAT6 - STAT5a STAT6 - Stat3 STAT6 - STAT1-beta STAT6 - Stat4 Stat3 - Stat5b Stat3 - STAT5a Stat3 - STAT6 Stat3 - STAT1-beta Stat3 - Stat4 STAT5a - STAT5a STAT5a - Stat5b STAT5a - Stat3 STAT5a - STAT6 STAT5a - STAT1-beta STAT5a - Stat4 Stat5b - Stat5b Stat5b - STAT5a Stat5b - Stat3 Stat5b - STAT6 Stat5b - STAT1-beta Stat5b - Stat4 Stat2 - STAT1-beta	Y51H4A.17 - Y51H4A.17

---

Conserved subnet 97:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-08).

Ortholog Groups
KOG3430	Dynein light chain type 1
KOG4081	Dynein light chain

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG3430 - KOG4081	Dnclc1 - tctex1	LC8 - Tctex-1	ctp - Dlc90F

---

Conserved subnet 98:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-06).

Ortholog Groups
KOG0775	Transcription factor SIX and related HOX domain proteins
KOG3107	Predicted haloacid dehalogenase-like hydrolase (eyes absent)

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans
KOG0775 - KOG3107	Six1 - Eya3 Six1 - Eya4 Six2 - Eya4	GI:17136492 - eya	C10G8.7 - C49A1.4 F56A12.1 - C49A1.4

---

Conserved subnet 99:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-06).

Ortholog Groups
KOG0639	Transducin-like enhancer of split protein (contains WD40 repeats)
KOG0775	Transcription factor SIX and related HOX domain proteins

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG0639 - KOG0775	Grg4 - Six6	TLE1 - SIX3 TLE1 - SIX2 TLE1 - SIX1 TLE1 - SIX6 TLE3 - SIX3 AES - SIX3 AES - SIX2 AES - SIX1 AES - SIX6	Groucho - GI:17136492 Groucho - Optix

---

Conserved subnet 100:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-06).

Ortholog Groups
KOG1010	Rb (Retinoblastoma tumor suppressor)-related protein
KOG2829	E2F-like protein

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG1010 - KOG2829	DIP:582N - DIP:724N	pRB - DIP:294N pRB - DP1 RB1 - DP1 RB1 - DIP:294N RB1 - DIP:724N RB1 - TFDP2 p107 - DP1 p107 - DIP:294N p107 - TFDP2 p130 - DIP:294N p130 - TFDP2 p130 - DP1	RBF - GI:24653311 RBF - dDP

---

Conserved subnet 101:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<8e-05).

Ortholog Groups
KOG0789	Protein tyrosine phosphatase

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG0789 - KOG0789	RPTP-alpha - RPTP-alpha	CD45 - CD45	Ptp3 - Ptp2 Ptp2 - Ptp3

---

Conserved subnet 102:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-08).

Ortholog Groups
KOG0603	Ribosomal protein S6 kinase
HG48302	Homologene family 48302

Conserved Interactions
Interaction	Mus musculus	Drosophila melanogaster	Oryza sativa
KOG0603 - HG48302	Rsk2 - Msk1	Pk61C - DIP:20399N DIP:20399N - Pk61C DIP:23499N - DIP:17324N	putative protein kinase - OsMAP3

---

Conserved subnet 103:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<8e-05).

Ortholog Groups
KOG0676	Actin and related proteins
KOG4261	Talin

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG0676 - KOG4261	Act1p - Talin Acta1 - Talin	Actin - Talin2 ACTG1 - Talin 1 Actin-like 7A - Talin 1 ACTC - Talin 1	actin - TLN1

---

Conserved subnet 104:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<8e-07).

Ortholog Groups
KOG3119	Basic region leucine zipper transcription factor

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Caenorhabditis elegans
KOG3119 - KOG3119	Tef - Tef	TEF - HLF TEF - C/EBP-gamma TEF - CHOP TEF - TEF CHOP - HLF CHOP - C/EBP-gamma CHOP - CHOP CHOP - TEF CHOP - DDIT3 C/EBP-gamma - HLF C/EBP-gamma - CHOP C/EBP-gamma - TEF C/EBP-gamma - DDIT3 HLF - HLF HLF - C/EBP-gamma HLF - CHOP HLF - TEF DDIT3 - C/EBP-gamma DDIT3 - CHOP	K08F8.2 - ZK909.4 K08F8.2 - Y51H4A.4 K08F8.2 - D1005.3 D1005.3 - K08F8.2 Y51H4A.4 - ZK909.4 Y51H4A.4 - K08F8.2 ZK909.4 - Y51H4A.4 ZK909.4 - K08F8.2

---

Conserved subnet 105:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<9e-04).

Ortholog Groups
KOG1118	Lysophosphatidic acid acyltransferase endophilin/SH3GL, involved in synaptic vesicle formation
KOG3601	Adaptor protein GRB2, contains SH2 and SH3 domains

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Saccharomyces cerevisiae
KOG1118 - KOG3601	Sorbs1 - Grb2 SORBS1 - Grb2	Endophilin A2 - Grb2 endophilin A1 - Grb2 Endophilin A3 - Grb2	Ysc84p - Lsb2 Ysc84p - Lsb1

---

Conserved subnet 106:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-07).

Ortholog Groups
KOG1226	Integrin beta subunit (N-terminal portion of extracellular region)
KOG3637	Vitronectin receptor, alpha subunit

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster
KOG1226 - KOG3637	Itgb1 - Itga6 Itgb1 - Itga3 Itgb1 - ITGA5 integrin-beta2 - Integrin-alphaL	integrin-beta-1 - ITGAV integrin-beta-1 - VLA5-alpha5 integrin-beta-1 - integrin alpha-4 integrin-beta-1 - ITGA3 integrin-beta-1 - VLA2-alpha2 integrin-beta-1 - VLA6-alpha6 integrin-beta-1 - VLA3-alpha3 integrin-beta-1 - DIP:206N Integrin-beta6 - ITGAV integrin-beta-5 - ITGAV Integrin-beta4 - VLA6-alpha6 Integrin-beta7 - integrin alpha-4 Integrin-beta7 - integrin alpha-E Integrin-beta8 - ITGAV	mys - scb

---

Conserved subnet 107:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-09).

Ortholog Groups
HG14229	Homologene family 14229
HG68224	Homologene family 68224

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Oryza sativa
HG14229 - HG68224	KIAA0465 - p230	DIP:25932N - C14H10.2 DIP:25932N - F01G10.5 DIP:25932N - LIN-5 MYO-2 - UNC-54 LFI-1 - LIN-5	putative CCAAT displacement protein - myosin heavy chain-like protein putative CCAAT displacement protein - Kinesin-like calmodulin-binding protein-like protein myosin heavy chain-like protein - putative CCAAT displacement protein myosin heavy chain-like protein - Kinesin-like calmodulin-binding protein-like protein centromere protein-like protein - OSJNBB0073N24.16

---

Conserved subnet 108:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-08).

Ortholog Groups
KOG2351	RNA polymerase II, fourth largest subunit
KOG3497	DNA-directed RNA polymerase, subunit RPB10

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2351 - KOG3497	hRPB4 - hRPB10-beta	Rpb4 - Rpb10 DIP:17797N - Rpb10	RPB4 - Rpb10

---

Conserved subnet 109:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-06).

Ortholog Groups
KOG1818	Membrane trafficking and cell signaling protein HRS, contains VHS and FYVE domains
KOG2391	Vacuolar sorting protein/ubiquitin receptor VPS23

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1818 - KOG2391	HRS - TSG101	Hrs - TSG101	Vps27 - Vps23

---

Conserved subnet 110:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-07).

Ortholog Groups
KOG2519	5'-3' exonuclease
KOG2520	5'-3' exonuclease

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2519 - KOG2520	FEN1 - DIP:750N	DIP:18807N - CG32956	Rad27 - Yen1p

---

Conserved subnet 111:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<9e-08).

Ortholog Groups
KOG1557	Fructose-biphosphate aldolase

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG1557 - KOG1557	ALDOB - ALDOB	DIP:19378N - DIP:19378N DIP:19378N - Ald Ald - Ald Ald - Ald Ald - DIP:19378N	CE01225 - CE01225 T05D4.1 - T05D4.1

---

Conserved subnet 112:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-10).

Ortholog Groups
KOG0804	Cytoplasmic Zn-finger protein BRAP2 (BRCA1 associated protein)

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0804 - KOG0804	IMP - IMP	CG5555 - CG5555	DIP:2987N - DIP:2987N

---

Conserved subnet 113:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-03).

Ortholog Groups
KOG0595	Serine/threonine-protein kinase involved in autophagy
KOG0660	Mitogen-activated protein kinase

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Arabidopsis thaliana
KOG0595 - KOG0660	CLIK1 - MAPK13	CG10967 - CG32703	MPK5 - MPK4 MPK5 - MPK6

---

Conserved subnet 114:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-09).

Ortholog Groups
KOG0595	Serine/threonine-protein kinase involved in autophagy

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0595 - KOG0595	CLIK1 - CLIK1	UNC-51 - UNC-51	Apg1 - Apg1

---

Conserved subnet 115:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 4 organisms (p<4e-12).

Ortholog Groups
KOG0833	Cytidine deaminase

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0833 - KOG0833	2210401N16Rik - 2210401N16Rik	CDA - CDA	CG8360 - CG8360 CG8349 - CG8349	CDD1 - CDD1

---

Conserved subnet 116:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 4 organisms (p<9e-14).

Ortholog Groups
KOG2698	GTP cyclohydrolase I

Conserved Interactions
Interaction	Rattus norvegicus	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2698 - KOG2698	Gch - Gch	GCH1 - GCH1	DIP:24104N - DIP:24104N GI:24656796 - GI:24656796	Fol2 - Fol2

---

Conserved subnet 117:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-11).

Ortholog Groups
KOG3304	Surfeit family protein 5
KOG4057	Uncharacterized conserved protein

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG3304 - KOG4057	Surf5 - HSPC296	Med24 - Med21	ZK970.3 - R144.9

---

Conserved subnet 118:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 5 organisms (p<4e-14).

Ortholog Groups
KOG1695	Glutathione S-transferase

Conserved Interactions
Interaction	Rattus norvegicus	Mus musculus	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG1695 - KOG1695	Ptgds2 - Ptgds2	Gstp2 - Gstp2	GSTM1 - GSTM1 GSTM3 - GSTM2 GSTA4 - GSTA4 GSTM2 - GSTM2 GSTM2 - GSTM3 GSTM4 - GSTM4 GSTP1 - GSTP1 Hematopoietic Prostagladin D Synthase - Hematopoietic Prostagladin D Synthase	GstS1 - GstS1	T28A11.11 - R107.7 R107.7 - T28A11.11

---

Conserved subnet 119:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<5e-07).

Ortholog Groups
KOG0871	Class 2 transcription repressor NC2, beta subunit (Dr1)
KOG1659	Class 2 transcription repressor NC2, alpha subunit (DRAP1)

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0871 - KOG1659	DR1 - NC2	NC2beta - NC2alpha NC2beta - DIP:17583N	Ncb2 - Bur6

---

Conserved subnet 120:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<3e-06).

Ortholog Groups
KOG3591	Alpha crystallins

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG3591 - KOG3591	HalphaA-crystallin - HalphaB-crystallin HalphaB-crystallin - HalphaA-crystallin Hsp27 - HSP22 HSP22 - HSP22 HSP22 - Hsp27	CG7409 - CG32041 CG32041 - Hsp27 CG32041 - CG7409 DIP:18793N - DIP:18793N Hsp26 - Hsp23 Hsp26 - Hsp27 Hsp27 - CG32041 Hsp27 - Hsp26 Hsp27 - Hsp23 Hsp67Bc - Hsp23 Hsp23 - Hsp26 Hsp23 - Hsp67Bc Hsp23 - Hsp27	T22A3.2 - F52E1.7 F38E11.2 - C14B9.1 F52E1.7 - F52E1.7 F52E1.7 - T22A3.2 C14B9.1 - F38E11.2

---

Conserved subnet 121:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-13).

Ortholog Groups
KOG3886	GTP-binding protein
KOG3887	Predicted small GTPase involved in nuclear protein import

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG3886 - KOG3887	RRAGA - RRAGC RRAGA - RRAGD	CG11968 - CG8707	GTR1 - GTR2

---

Conserved subnet 122:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-11).

Ortholog Groups
KOG1522	RNA polymerase II, subunit POLR2C/RPB3
KOG4392	RNA polymerase, subunit L

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1522 - KOG4392	hRPB3 - hHRPB11	DIP:18234N - Rpb11 RpII33 - Rpb11	Rpb3 - Rpb11

---

Conserved subnet 123:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 4 organisms (p<3e-06).

Ortholog Groups
KOG0888	Nucleoside diphosphate kinase

Conserved Interactions
Interaction	Bos taurus	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0888 - KOG0888	Nucleoside Diphosphate Transferase - Nucleoside Diphosphate Transferase Nucleoside Diphosphate Transferase - Nucleoside Diphosphate Transferase Nucleoside Diphosphate Transferase - Nucleoside Diphosphate Transferase Nucleoside Diphosphate Transferase - Nucleoside Diphosphate Transferase	NME4 - NME4 NME1 - NME1 nm23-H2 - nm23-H2	awd - awd awd - awd awd - awd	Ynk1 - Ynk1

---

Conserved subnet 124:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-08).

Ortholog Groups
KOG1068	Exosomal 3'-5' exoribonuclease complex, subunit Rrp41 and related exoribonucleases
KOG3013	Exosomal 3'-5' exoribonuclease complex, subunit Rrp4

Conserved Interactions
Interaction	Homo sapiens	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG1068 - KOG3013	hRrp41p - hRrp4p hMtr3p - hRrp4p	Mtr3 - RRP4 SKI6 - RRP4	AtRrp41p - AtRrp4p

---

Conserved subnet 125:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-07).

Ortholog Groups
KOG1125	TPR repeat-containing protein
KOG2629	Peroxisomal membrane anchor protein (peroxin)

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG1125 - KOG2629	PEX5 - PEX14	DIP:17101N - CG4289 EG:63B12.5 - CG4289	Pex5 - Pex14

---

Conserved subnet 126:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<7e-10).

Ortholog Groups
KOG3473	RNA polymerase II transcription elongation factor Elongin/SIII, subunit elongin C
KOG4495	RNA polymerase II transcription elongation factor Elongin/SIII, subunit elongin B

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG3473 - KOG4495	Elongin C - Elongin B	Elongin-C - Elongin-B	Y82E9BR.15 - Y41C4A.10

---

Conserved subnet 127:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<1e-12).

Ortholog Groups
KOG3219	Transcription initiation factor TFIID, subunit TAF11
KOG3901	Transcription initiation factor IID subunit

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG3219 - KOG3901	1110038O14Rik - 1810004N01Rik	TAF11 - Tafii18 TAF11 - DIP:900N	Taf11 - Taf13	Taf40 - Taf19

---

Conserved subnet 128:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-03).

Ortholog Groups
KOG0977	Nuclear envelope protein lamin, intermediate filament superfamily
KOG2577	Transcription factor E2F/dimerization partner (TDP)

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans
KOG0977 - KOG2577	Lamin C - E2F2	Mhc - E2f2	IFB-2 - efl-2 ifp-1 - efl-2

---

Conserved subnet 129:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<6e-10).

Ortholog Groups
KOG2015	NEDD8-activating complex, catalytic component UBA3
KOG2016	NEDD8-activating complex, APP-BP1/UBA5 component

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2015 - KOG2016	UBE1C - APP-BP1	CG13343 - CG7828	Uba3 - Ula1

---

Conserved subnet 130:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<6e-09).

Ortholog Groups
KOG0934	Clathrin adaptor complex, small subunit
KOG1062	Vesicle coat complex AP-1, gamma subunit

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0934 - KOG1062	sigma-1A - gamma-1	AP-1sigma - DIP:20066N AP-1sigma - AP-1gamma	Aps1 - Apl4

---

Conserved subnet 131:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 4 organisms (p<4e-15).

Ortholog Groups
KOG2794	Delta-aminolevulinic acid dehydratase

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2794 - KOG2794	Alad - Alad	ALAD - ALAD	CG10335 - CG10335	Hem2 - Hem2

---

Conserved subnet 132:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<5e-12).

Ortholog Groups
KOG1643	Triosephosphate isomerase

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1643 - KOG1643	TPI1 - TPI1	tpi-1 - tpi-1	TPI1 - TPI1

---

Conserved subnet 133:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-03).

Ortholog Groups
KOG0658	Glycogen synthase kinase-3
KOG0890	Protein kinase of the PI-3 kinase family involved in mitotic growth, DNA repair and meiotic recombination

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG0658 - KOG0890	GSK3-beta - ATR	CG30171 - mei-41	Yol128c - Mec1

---

Conserved subnet 134:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<6e-08).

Ortholog Groups
KOG0851	Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins
KOG3108	Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit

Conserved Interactions
Interaction	Mus musculus	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0851 - KOG3108	RPA1 - RPA2	RPA - RPA2 RPA - DIP:24241N	F18A1.5 - M04F3.1	Rfa1 - Rfa2

---

Conserved subnet 135:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<6e-09).

Ortholog Groups
KOG2841	Structure-specific endonuclease ERCC1-XPF, ERCC1 component
KOG4017	DNA excision repair protein XPA/XPAC/RAD14

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG2841 - KOG4017	DIP:24235N - DIP:24191N	Ercc1 - Xpac	Rad10 - Rad14

---

Conserved subnet 136:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<6e-09).

Ortholog Groups
KOG3133	40 kDa farnesylated protein associated with peroxisomes
KOG3875	Peroxisomal biogenesis protein peroxin

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae
KOG3133 - KOG3875	PEX19 - PEX13	DIP:19768N - CG4663	PEX19 - Pex13

---

Conserved subnet 137:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<3e-06).

Ortholog Groups
KOG2577	Transcription factor E2F/dimerization partner (TDP)
KOG2829	E2F-like protein

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Oryza sativa
KOG2577 - KOG2829	E2F1 - DP1 E2F1 - DIP:724N E2F1 - DIP:294N E2F3 - DP1 E2F3 - DIP:294N E2F3 - DIP:724N E2F-5 - DP1 E2F2 - DIP:294N E2F2 - DP1 E2F2 - DIP:724N E2F4 - DIP:294N E2F4 - TFDP2 E2F4 - DP1 E2F4 - DIP:724N	E2f2 - GI:24653311 E2f2 - dDP dE2F - GI:24653311 dE2F - dDP	OSE2F1 - DP TF OSE2F1 - DP protein

---

Conserved subnet 138:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<5e-01).

Ortholog Groups
KOG0581	Mitogen-activated protein kinase kinase (MAP2K)
KOG0598	Ribosomal protein S6 kinase and related proteins

Conserved Interactions
Interaction	Drosophila melanogaster	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0581 - KOG0598	DIP:23499N - Bin4 CG30171 - Bin4	Mkk1 - Ybr028c Mkk2 - Ypk2	MKK2 - MPK5

---

Conserved subnet 139:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<9e-04).

Ortholog Groups
KOG0604	MAP kinase-activated protein kinase 2
KOG0660	Mitogen-activated protein kinase

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Arabidopsis thaliana
KOG0604 - KOG0660	MAPk-Ak2 - p38b	C44C8.6 - B0218.3	MPK5 - MPK4 MPK5 - MPK6

---

Conserved subnet 140:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<4e-13).

Ortholog Groups
KOG1816	Ubiquitin fusion-degradation protein
KOG2834	Nuclear pore complex, rNpl4 component (sc Npl4)

Conserved Interactions
Interaction	Rattus norvegicus	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1816 - KOG2834	Ufd1 - Npl4	Ufd1-like - DIP:23771N	F19B6.2 - DIP:25816N F19B6.2 - F59E12.4	UFD1 - Npl4

---

Conserved subnet 141:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-10).

Ortholog Groups
KOG2638	UDP-glucose pyrophosphorylase

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG2638 - KOG2638	DIP:22334N - DIP:22334N	DIP:24939N - DIP:24939N K08E3.5 - K08E3.5	Ugp1 - Ugp1

---

Conserved subnet 142:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-10).

Ortholog Groups
KOG3048	Molecular chaperone Prefoldin, subunit 5
KOG4098	Molecular chaperone Prefoldin, subunit 2

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG3048 - KOG4098	CG7048 - l(3)01239	R151.9 - H20J04.5	GIM5 - GIM4

---

Conserved subnet 143:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<6e-07).

Ortholog Groups
KOG1555	26S proteasome regulatory complex, subunit RPN11
KOG1556	26S proteasome regulatory complex, subunit RPN8/PSMD7

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1555 - KOG1556	Rpn11 - Mov34	K07D4.3 - R12E2.3	RPN11 - Rpn8

---

Conserved subnet 144:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 3 organisms (p<2e-08).

Ortholog Groups
KOG2835	Phosphoribosylamidoimidazole-succinocarboxamide synthase

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG2835 - KOG2835	ade5 - ade5	B0286.3 - B0286.3	Ade2 - Ade2

---

Conserved subnet 145:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-02).

Ortholog Groups
KOG0594	Protein kinase PCTAIRE and related kinases
KOG1374	Gamma tubulin

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0594 - KOG1374	CG30171 - betaTub56D cdc2 - betaTub56D	T05G5.3 - F58A4.8	Cdc28 - Tub4

---

Conserved subnet 146:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<4e-07).

Ortholog Groups
KOG1309	Suppressor of G2 allele of skp1
KOG1474	Transcription initiation factor TFIID, subunit BDF1 and related bromodomain proteins

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1309 - KOG1474	CG9617 - CG13597	D1054.3 - F13C5.2	Sgt1 - Bdf1

---

Conserved subnet 147:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<9e-03).

Ortholog Groups
KOG0583	Serine/threonine protein kinase
KOG2166	Cullins

Conserved Interactions
Interaction	Drosophila melanogaster	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0583 - KOG2166	CG30171 - lin19	Snf1 - Cdc53	ASK1 - CUL1

---

Conserved subnet 148:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<9e-13).

Ortholog Groups
KOG1654	Microtubule-associated anchor protein involved in autophagy and membrane trafficking
KOG2674	Cysteine protease required for autophagy - Apg4p/Aut2p

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1654 - KOG2674	CG12334 - CG4428	ZK593.6 - Y87G2A.3 C32D5.9 - Y87G2A.3	AUT7 - Aut2p

---

Conserved subnet 149:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-03).

Ortholog Groups
KOG0580	Serine/threonine protein kinase
KOG2260	Cell division cycle 37 protein, CDC37

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0580 - KOG2260	Aurora - Cdc37	K07C11.2 - W08F4.8	Ipl1 - Cdc37

---

Conserved subnet 150:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-10).

Ortholog Groups
KOG1942	DNA helicase, TBP-interacting protein
KOG2680	DNA helicase TIP49, TBP-interacting protein

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1942 - KOG2680	pont - rept	C27H6.2 - T22D1.10	Rvb1 - Rvb2

---

Conserved subnet 151:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<5e-10).

Ortholog Groups
KOG1978	DNA mismatch repair protein - MLH2/PMS1/Pms2 family
KOG1979	DNA mismatch repair protein - MLH1 family

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG1978 - KOG1979	hPMS1 - MLH1 PMS2 - MLH1	Pms2 - Mlh1	mlh-1 - T28A8.7 H12C20.2 - mlh-1 H12C20.2 - T28A8.7	Pms1p - Mlh1 MLH2 - Mlh1 Pms1 - Mlh1

---

Conserved subnet 152:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<1e-03).

Ortholog Groups
KOG1724	SCF ubiquitin ligase, Skp1 component
KOG1947	Leucine rich repeat proteins, some proteins contain F-box

Conserved Interactions
Interaction	Drosophila melanogaster	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG1724 - KOG1947	skpA - ppa skpB - CG8272	Skp1 - Grr1	ASK2 - FBL6 ASK2 - SKIP1 ASK2 - SKIP18 ASK2 - COI1 ASK2 - SKIP19 ASK2 - TIR1 ASK11 - FBL6 ASK11 - SKIP1 ASK11 - SKIP18 ASK11 - COI1 ASK11 - SKIP19 ASK11 - TIR1 ASK12 - FBL6 ASK12 - COI1 ASK4 - SKIP18 ASK1 - FBL6 ASK1 - SKIP1 ASK1 - COI1 ASK1 - SKIP19 ASK1 - TIR1 ASK9 - TIR1 ASK19 - SKIP18

---

Conserved subnet 153:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<7e-04).

Ortholog Groups
KOG0616	cAMP-dependent protein kinase catalytic subunit (PKA)
KOG1113	cAMP-dependent protein kinase types I and II, regulatory subunit

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0616 - KOG1113	CG30171 - DIP:17163N	kin-1 - R07E4.6	Tpk1 - Bcy1 Tpk3 - Bcy1 TPK2 - Bcy1

---

Conserved subnet 154:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 3 organisms (p<2e-05).

Ortholog Groups
KOG0998	Synaptic vesicle protein EHS-1 and related EH domain proteins
KOG3601	Adaptor protein GRB2, contains SH2 and SH3 domains

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae
KOG0998 - KOG3601	Dap160 - drk	ZK1248.3 - sem-5 ZK1248.3 - DIP:25104N	Ede1 - Ysc84p Pan1 - Ysc84p End3 - Lsb2 End3 - Ysc84p End3 - Lsb1

---

Conserved subnet 155:
1 conserved interactions between 1 ortholog groups.
This subnet exists in 4 organisms (p<5e-05).

Ortholog Groups
KOG0867	Glutathione S-transferase

Conserved Interactions
Interaction	Homo sapiens	Drosophila melanogaster	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0867 - KOG0867	EF1G - EF1G GSTT2 - GSTT2	CG17524 - GstE2 GstE2 - CG17524 GstD4 - GstD6 GstD6 - GstD4	GTT1 - GTT2 GTT1 - GTT1 GTT2 - GTT2 GTT2 - GTT1 URE2 - URE2 Tef4p - Cam1p Cam1p - Tef4p	Glutathione S-Transferase - Glutathione S-Transferase

---

Conserved subnet 156:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<3e-09).

Ortholog Groups
KOG2326	DNA-binding subunit of a DNA-dependent protein kinase (Ku80 autoantigen)
KOG2327	DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG2326 - KOG2327	Ku80 - Ku70	R07E5.8 - Y47D3A.4	Yku80 - Yku70	AtKu80 - AtKu70

---

Conserved subnet 157:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<1e-09).

Ortholog Groups
KOG0962	DNA repair protein RAD50, ABC-type ATPase/SMC superfamily
KOG2310	DNA repair exonuclease MRE11

Conserved Interactions
Interaction	Homo sapiens	Caenorhabditis elegans	Saccharomyces cerevisiae	Arabidopsis thaliana
KOG0962 - KOG2310	Rad50 - Mre11	T04H1.4 - ZC302.1	RAD50 - MRE11	Rad50 - Mre11

---

Conserved subnet 158:
1 conserved interactions between 2 ortholog groups.
This subnet exists in 4 organisms (p<3e-11).

Ortholog Groups
KOG2239	Transcription factor containing NAC and TS-N domains
KOG2240	RNA polymerase II general transcription factor BTF3 and related proteins

Conserved Interactions
Interaction	Drosophila melanogaster	Caenorhabditis elegans	Saccharomyces cerevisiae	Oryza sativa
KOG2239 - KOG2240	CG4415 - CG11835 Nacalpha - bic Nacalpha - DIP:22390N Nacalpha - CG11835	Y65B4BR.5 - C56C10.8	Egd2 - Btt1	putative nascent polypeptide-associated complex alpha chain - Putative transcription factor BTF3

---